Best TWAS P=3.54e-08 · Best GWAS P=1.26e-08 conditioned to 0.0707
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | KAT2B | 0.19 | 0.00 | lasso | 5 | 0.00 | 4.4e-01 | -5.7 | 5.2 | 2.1e-07 | -0.88 | 0.03 | 0.51 | FALSE |
| 2 | GTEx | Nerve Tibial | KAT2B | 0.28 | 0.27 | enet | 9 | 0.29 | 1.8e-20 | -5.0 | -5.5 | 3.5e-08 | 0.87 | 0.03 | 0.97 | TRUE |
| 3 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | SGOL1 | 0.03 | 0.04 | blup | 70 | 0.04 | 2.6e-04 | 4.3 | 5.5 | 4.9e-08 | -0.52 | 0.05 | 0.80 | FALSE |