TWAS
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About
Usage
Models
Genes
Traits
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Traits
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High blood pressure
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chr3:10,617,048-12,293,966
Best TWAS P=3.92e-08 · Best GWAS P=1.7e-10 conditioned to 0.000911
10.6M
10.8M
11M
11.2M
11.4M
11.6M
11.8M
12M
12.2M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Muscle Skeletal
ATG7
0.06
0.02
lasso
4
0.03
8.6e-04
-5.7
5.5
3.9e-08
-0.90
0.05
0.93
TRUE
1
CommonMind
Brain Pre-frontal Cortex
ATG7
0.07
0.07
lasso
3
0.07
3.3e-09
-4.6
5.3
8.6e-08
-0.89
0.09
0.91
FALSE
4
The Cancer Genome Atlas
Head and Neck Squamous Cell Carcinoma
ATG7
0.05
0.05
lasso
4
0.03
3.2e-04
-5.2
5.3
9.9e-08
-0.87
0.03
0.93
FALSE
3
The Cancer Genome Atlas
Bladder Urothelial Carcinoma
ATG7
0.06
0.01
lasso
2
0.02
1.2e-02
-3.9
5.3
1.2e-07
-0.81
0.13
0.33
FALSE