Best TWAS P=3.92e-08 · Best GWAS P=1.7e-10 conditioned to 0.000911
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ATG7 | 0.07 | 0.07 | lasso | 3 | 0.07 | 3.3e-09 | -4.6 | 5.3 | 8.6e-08 | -0.89 | 0.09 | 0.91 | FALSE |
| 2 | GTEx | Muscle Skeletal | ATG7 | 0.06 | 0.02 | lasso | 4 | 0.03 | 8.6e-04 | -5.7 | 5.5 | 3.9e-08 | -0.90 | 0.05 | 0.93 | TRUE |
| 3 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | ATG7 | 0.06 | 0.01 | lasso | 2 | 0.02 | 1.2e-02 | -3.9 | 5.3 | 1.2e-07 | -0.81 | 0.13 | 0.33 | FALSE |
| 4 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | ATG7 | 0.05 | 0.05 | lasso | 4 | 0.03 | 3.2e-04 | -5.2 | 5.3 | 9.9e-08 | -0.87 | 0.03 | 0.93 | FALSE |