Best TWAS P=2.22e-08 · Best GWAS P=6.65e-12 conditioned to 8.09e-11
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | GUCY1A3 | 0.29 | 0.12 | lasso | 6 | 0.19 | 1.7e-10 | 4.8 | -5.2 | 2.6e-07 | 0.04 | 0.99 | 0.00 | FALSE |
| 2 | GTEx | Artery Aorta | RP11-588K22.2 | 0.22 | 0.11 | lasso | 11 | 0.11 | 1.6e-06 | 4.8 | -5.6 | 2.2e-08 | 0.07 | 0.73 | 0.05 | TRUE |