TWAS
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Traits
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High blood pressure
:
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chr4:110,590,479-112,179,424
Best TWAS P=2.95e-07 · Best GWAS P=6.43e-13 conditioned to 5.94e-09
110.6M
110.8M
111M
111.2M
111.4M
111.6M
111.8M
112M
112.2M
0
2
4
6
8
10
12
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
ROSMAP
Brain Pre-frontal Cortex
ENPEP
0.04
0.01
blup
486
0.01
0.0057
4.9
-5.1
2.9e-07
-0.33
0.19
0.3
TRUE