Best TWAS P=3.23e-09 · Best GWAS P=3.62e-07 conditioned to 0.483
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | PIGV | 0.09 | 0.07 | enet | 25 | 0.13 | 3.4e-08 | 4.4 | -5.6 | 2.0e-08 | 0.04 | 0.16 | 0.79 | TRUE |
| 2 | GTEx | Thyroid | ZDHHC18 | 0.11 | 0.10 | lasso | 4 | 0.13 | 4.2e-10 | 5.0 | 5.2 | 2.5e-07 | -0.05 | 0.02 | 0.98 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | CD164L2 | 0.16 | 0.13 | bslmm | 220 | 0.16 | 2.4e-20 | -4.6 | -5.6 | 1.7e-08 | 0.88 | 0.07 | 0.92 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CD164L2 | 0.04 | 0.06 | blup | 36 | 0.06 | 9.2e-08 | -4.8 | -5.4 | 7.6e-08 | 0.96 | 0.02 | 0.97 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | FCN3 | 0.03 | 0.03 | blup | 35 | 0.02 | 8.0e-03 | -4.7 | 5.9 | 3.2e-09 | -0.74 | 0.02 | 0.65 | TRUE |