TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
High blood pressure
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chr1:26,428,864-28,406,173
Best TWAS P=3.23e-09 · Best GWAS P=3.62e-07 conditioned to 0.483
26.5M
27M
27.5M
28M
28.5M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
5
The Cancer Genome Atlas
Thyroid Carcinoma
FCN3
0.03
0.03
blup
35
0.02
8.0e-03
-4.7
5.9
3.2e-09
-0.74
0.02
0.65
TRUE
1
GTEx
Esophagus Muscularis
PIGV
0.09
0.07
enet
25
0.13
3.4e-08
4.4
-5.6
2.0e-08
0.04
0.16
0.79
TRUE
3
ROSMAP
Brain Pre-frontal Cortex
CD164L2
0.16
0.13
bslmm
220
0.16
2.4e-20
-4.6
-5.6
1.7e-08
0.88
0.07
0.92
FALSE
4
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
CD164L2
0.04
0.06
blup
36
0.06
9.2e-08
-4.8
-5.4
7.6e-08
0.96
0.02
0.97
FALSE
2
GTEx
Thyroid
ZDHHC18
0.11
0.10
lasso
4
0.13
4.2e-10
5.0
5.2
2.5e-07
-0.05
0.02
0.98
FALSE