TWAS hub - CD164L2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	ROSMAP	Brain Pre-frontal Cortex	0.1558	0.0394	5.6e-17	0.134	0.160	0.160	0.162	0.152	7.3e-17	5.3e-20	4.6e-20	2.4e-20	4.7e-19
2	TCGA	Kidney Renal Clear Cell Carcinoma	0.0425	0.0184	2.4e-07	0.065	0.064	0.055	NA	0.061	9.0e-08	9.2e-08	8.7e-07	NA	2.1e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Medication: Amlodipine	16.5	23.2	28.6	-5.3	-4.2
High blood pressure	10.9	30.4	31.8	-5.6	-5.4
Vascular/heart problems diagnosed by doctor	10.8	29.4	29.5	5.4	5.4
Hypertension (Self-reported)	10.2	28.4	29.6	-5.4	-5.2
Medication: Bendroflumethiazide	9.9	15.0	18.3	-4.3	-3.4
Heart attack	9.2	11.8	13.2	-3.6	-3.2
Heart attack/myocardial infarction (self-reported)	8.4	10.8	12.6	-3.5	-3.0
Cardiovascular Disease	8.2	27.1	33.4	-5.8	-4.6
Medication: Blood pressure	7.0	13.3	16.3	-4.0	-3.2
Medication: Omeprazole (e.g. Zanprol)	6.9	8.4	8.5	-2.9	-2.9
Illnesses of father: High blood pressure	6.7	8.3	10.2	-2.5	-3.2
Systolic Blood Pressure	6.5	32.5	34.5	-5.9	-5.5
Osteoporosis (self-reported)	6.4	7.9	8.5	-2.7	-2.9
Medication: Blood pressure	5.8	10.2	12.5	-3.5	-2.8
Supplements: Glucosamine	5.6	7.3	7.5	2.7	2.7
Medication for cholesterol	5.6	8.5	11.4	3.4	2.4
Noisy workplace	5.2	6.4	7.5	-2.7	-2.3
Medication: Atenolol	5.1	6.3	7.7	-2.2	-2.8
Depression (self-reported)	5.0	6.0	8.9	3.0	1.8
Medication: Levothyroxine sodium	4.9	8.3	9.5	-3.1	-2.7
High cholesterol (Self-reported)	4.7	8.4	12.7	-3.6	-2.0
Medication: Lisinopril	4.7	6.1	6.5	-2.5	-2.4
Reaction Time	4.3	8.3	10.0	3.2	2.5
Medication for cholesterol, blood pressure or diabetes	4.1	6.8	10.0	3.2	1.9
Medication: Ramipril	4.0	5.1	6.7	-2.6	-1.9
Heart disease (mother)	3.9	4.7	5.2	-2.3	-2.0
Alcohol intake versus 10 years previously	3.8	5.7	6.4	-2.2	-2.5
Pulse wave Arterial Stiffness index	3.8	4.5	5.5	1.9	2.3
Had other major operations	3.7	4.5	5.2	-2.0	-2.3
Cholesterol lowering medication	3.7	5.5	7.4	-2.7	-1.9
Systolic blood pressure, automated reading	3.4	9.8	11.5	-2.8	-3.4
Exposure to tobacco smoke outside home	3.4	4.5	4.6	2.2	2.1
Alcohol intake frequency.	3.4	7.8	9.2	-2.5	-3.0
Maternal smoking around birth	3.3	4.7	4.9	2.1	2.2
High blood pressure (siblings)	3.3	4.7	4.8	-2.2	-2.1
Long-standing illness, disability or infirmity	3.3	5.1	5.6	-2.4	-2.1
Mean time to correctly identify matches	3.2	6.2	6.8	2.6	2.4
Illnesses of father: Heart disease	3.2	4.5	6.0	-1.7	-2.4
Pulse wave peak to peak time	3.1	3.6	4.6	-1.6	-2.1
Tinnitus: Yes, now most or all of the time	3.0	3.5	6.2	-2.5	-0.9
Major Depression (MDD)	2.9	3.5	4.4	-2.1	-1.6
Father’s age at death	2.9	3.8	4.8	1.7	2.2
Medication: Cholesterol lowering	2.9	4.4	7.1	-2.7	-1.3
Angina (self-reported)	2.9	3.8	4.9	-2.2	-1.7
Chest pain or discomfort	2.9	4.2	4.9	-2.2	-1.9
Medication: Aspirin	2.9	3.8	4.2	-2.1	-1.8
Wheeze or whistling in the chest in last year	2.8	5.0	5.3	-2.2	-2.3
Commuting to job workplace: Public transport	2.8	3.3	3.9	-1.7	-2.0
Deep venous thrombosis (DVT) (self-reported)	2.8	3.6	5.0	2.2	1.5
Medication: Simvastatin	2.7	4.0	6.2	-2.5	-1.3
Medication: Lansoprazole	2.7	3.1	3.3	1.8	1.7
Number of live births	2.6	3.7	3.8	1.9	1.9
Family relationship satisfaction	2.6	3.2	3.3	-1.8	-1.8
Sitting height	2.5	18.1	21.1	-3.9	-4.6
Impedance of leg (left)	2.5	12.3	12.6	-3.5	-3.5
Loneliness, isolation	2.5	3.4	4.2	-1.6	-2.1
Blood clot in the leg (DVT)	2.4	3.1	4.2	2.0	1.4
Blood Eosinophil Count	2.3	17.8	25.5	-5.0	-3.2
Ever highly irritable/argumentative for 2 days	2.3	2.8	3.0	1.6	1.7
Medication: Seretide 50 evohaler	2.3	2.7	3.2	-1.8	-1.5
Alzheimer’s Disease (in father)	2.2	2.4	3.8	-1.9	-1.0
Other serious medical condition/disability diagnosed by doctor	2.2	2.9	3.2	-1.6	-1.8
Angina	2.2	2.9	3.5	-1.9	-1.5
Impedance of leg (right)	2.2	10.6	11.2	-3.4	-3.2
Back pain experienced in last month	2.2	3.2	3.5	-1.7	-1.9
Number of self-reported non-cancer illnesses	2.2	3.8	4.6	-2.1	-1.7
Hypothyroidism/myxoedema (self-reported)	2.1	4.1	4.2	-2.0	-2.0
Average weekly champagne plus white wine intake	2.1	2.9	3.7	1.4	1.9
Medication: Atorvastatin	2.0	2.5	4.0	-2.0	-1.0
Pulse rate, automated reading	1.9	6.2	7.5	2.2	2.7
Medication: Aspirin	1.9	2.5	3.3	-1.8	-1.3
Medication: Gliclazide	1.8	2.0	2.7	1.2	1.6
BMI	1.7	9.6	10.6	2.9	3.3
Average weekly fortified wine intake	1.7	2.0	2.6	1.2	1.6
High blood pressure (mother)	1.7	2.4	3.6	-1.1	-1.9
Medication: Ventolin 100micrograms inhaler	1.7	2.2	2.5	-1.6	-1.4
Diastolic blood pressure, automated reading	1.7	5.1	5.9	-2.4	-2.1
Alzheimer’s Disease (in mother)	1.6	1.9	2.5	1.1	1.6
Sensitivity / hurt feelings	1.6	2.7	3.0	1.6	1.7
Supplements: Zinc	1.6	1.7	2.4	1.5	1.1
Medication: Co-codamol	1.6	1.8	3.3	0.6	1.8
Diverticular disease/diverticulitis (self-reported)	1.6	1.9	2.2	-1.5	-1.2
Medication: Omeprazole	1.6	1.9	2.1	-1.3	-1.4
Taking other prescription medications	1.5	2.3	2.8	-1.7	-1.4
Hair/balding pattern: Pattern 2	1.5	2.0	2.5	-1.2	-1.6
Seen a psychiatrist for nerves, anxiety, tension or depression	1.5	1.9	2.1	-1.3	-1.5
Illnesses of father: None of the above (group 1)	1.5	1.9	2.7	1.0	1.6
Alcohol drinker status: Previous	1.5	1.7	2.0	-1.4	-1.2
Primary Biliary Cirrhosis	1.4	2.0	2.7	-1.1	-1.6
Chronic bronchitis/emphysema (father)	1.4	1.7	1.9	1.2	1.4
Overall health rating	1.4	3.0	3.3	-1.8	-1.6
Mineral and other dietary supplements	1.4	1.9	3.0	-1.0	-1.7
Age at First Birth	1.3	1.9	2.7	-1.6	-1.1
Lung cancer (father)	1.3	1.6	3.0	1.7	0.3
Medication for pain relief, constipation, heartburn	1.3	2.3	2.9	1.7	1.3
Hearing aid user	1.3	1.5	2.1	-1.4	-0.9
Fractured/broken bones in last 5 years	1.3	1.6	1.6	1.3	1.3
Number of treatments/medications taken	1.2	2.1	3.3	-1.8	-1.0
Hearing difficulty/problems: Yes	1.2	1.9	2.7	-1.7	-1.0
Hand grip strength (right)	1.2	3.3	3.8	-1.7	-1.9
Age when periods started (menarche)	1.2	2.9	4.0	1.4	2.0
Heel bone mineral density (BMD) T-score, automated (left)	1.2	2.8	3.0	1.7	1.6
Pulse wave reflection index	1.2	1.5	2.1	0.9	1.4
Glaucoma (self-reported)	1.2	1.4	2.2	0.7	1.5
Supplements: Calcium	1.2	1.4	1.7	-1.3	-1.0
Ovarian Cancer	1.1	1.4	2.3	1.5	0.8
Lung FEV1/FVC ratio	1.1	5.7	6.2	2.3	2.5
Chronotype (morning person)	1.1	2.5	2.7	-1.6	-1.6
Leg fat-free mass (left)	1.1	6.0	6.3	2.5	2.4
Leg predicted mass (left)	1.1	5.8	6.0	2.5	2.4
Waist circumference	1.1	4.2	5.8	1.6	2.4
Leg pain on walking	1.1	1.4	1.6	-1.3	-1.1
Arm fat mass (left)	1.1	4.5	6.2	1.7	2.5
Pain type(s) experienced in last month: Hip pain	1.1	1.3	1.4	-1.1	-1.2
Ever had prostate specific antigen (PSA) test	1.1	1.3	1.7	1.0	1.3
Breast Cancer	1.0	2.4	3.1	-1.8	-1.3
Lupus	1.0	1.6	1.9	-1.4	-1.1
Respiratory disease	1.0	2.1	3.2	-1.8	-1.1
Illnesses of siblings	1.0	1.3	1.6	1.2	1.1
Peak expiratory flow (PEF)	1.0	2.3	2.5	-1.6	-1.5
Birth weight	1.0	2.3	3.5	1.9	1.0
Shortness of breath walking on level ground	1.0	1.2	1.3	-1.0	-1.1
Leg fat-free mass (right)	1.0	5.5	6.2	2.5	2.2
Leg predicted mass (right)	1.0	5.3	6.1	2.5	2.1
Ever depressed for a whole week	1.0	1.3	2.1	1.4	0.7
Heel T-Score	0.9	6.8	8.2	2.3	2.9
Falls in the last year	0.9	1.3	1.9	-1.4	-0.8
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.2	1.2	1.1	1.1
Arm fat mass (right)	0.9	3.8	5.4	1.5	2.3
Breastfed as a baby	0.9	1.1	2.2	0.2	-1.5
Qualifications: O levels/GCSEs or equivalent	0.9	1.4	2.3	0.7	1.5
Headache pain in last month	0.9	1.5	1.7	1.3	1.1
Arm fat percentage (left)	0.9	3.8	5.4	1.5	2.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	1.9	3.0	1.7	0.9
Commuting to job workplace: Cycle	0.9	1.1	1.3	-1.1	-0.9
Impedance of whole body	0.9	4.4	4.6	-2.0	-2.1
Multivitamins +/- minerals	0.8	1.0	1.1	1.0	1.1
Stomach or abdominal pain in last month	0.8	1.0	1.9	-0.4	-1.4
Hearing difficulty/problems with background noise	0.8	1.2	1.6	-1.3	-0.9
Hair/balding pattern: Pattern 3	0.8	1.1	1.1	1.1	1.1
Hair/balding pattern: Pattern 4	0.8	2.0	3.5	-1.9	-0.7
Migraine (self-reported)	0.8	0.9	1.9	0.2	1.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	0.9	1.0	0.9	1.0
Supplements: Vitamin C	0.8	0.9	1.4	1.2	0.7
Qualifications: nursing, teaching	0.8	1.3	1.4	1.2	1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	1.0	1.0	-1.0	-1.0
Number of operations (self-reported)	0.8	1.1	1.4	-1.2	-0.9
Irritability	0.8	1.3	1.8	0.9	1.3
Schizophrenia vs Biploar Disorder	0.7	0.9	1.7	0.5	1.3
Prostate Cancer	0.7	1.0	1.7	0.6	1.3
HbA1C	0.7	0.7	1.4	0.3	1.2
Triglycerides	0.7	1.2	1.3	1.0	1.1
Blood Platelet Count	0.7	7.9	9.0	-3.0	-2.6
Neuroticism	0.7	1.8	2.2	-1.5	-1.2
Ever used hormone-replacement therapy (HRT)	0.7	0.9	1.5	0.5	1.2
Body mass index (BMI)	0.7	3.0	4.5	1.3	2.1
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.6	2.5	1.6	0.9
Arm fat percentage (right)	0.7	2.6	3.9	1.1	2.0
Asthma	0.7	1.4	2.4	-1.5	-0.6
Prospective memory result	0.7	0.9	1.1	1.0	0.8
Length of working week for main job	0.7	0.7	1.0	-1.0	-0.7
Chronic bronchitis/emphysema (mother)	0.7	0.8	1.2	0.6	1.1
Number of full sisters	0.7	0.9	1.3	1.1	0.7
Illnesses of siblings: Diabetes	0.7	0.9	1.5	-1.2	-0.5
Eye problems/disorders: Cataract	0.7	0.8	1.2	0.6	-1.1
Asthma (self-reported)	0.7	1.3	2.2	-1.5	-0.7
Risk taking	0.7	1.1	1.3	-1.1	-0.9
HDL Cholesterol	0.6	0.9	1.4	0.7	1.2
Waist Hip Ratio (WHR)	0.6	2.5	3.5	1.3	1.9
Smoking Status	0.6	1.5	1.9	1.1	1.4
Hand grip strength (left)	0.6	1.5	1.8	-1.1	-1.3
Diabetes (mother)	0.6	0.7	0.7	0.9	0.8
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	1.3	-0.7	-1.1
Qualifications: None of the above	0.6	1.2	1.8	-0.8	-1.3
Weight	0.6	2.7	3.6	1.4	1.9
Number of children fathered	0.6	0.6	1.0	0.5	1.0
Medication: Ibuprofen	0.6	0.7	1.1	1.1	0.5
Smoking status: Previous	0.6	1.0	1.0	1.0	0.9
Ever had bowel cancer screening	0.6	0.8	1.5	0.0	1.2
Diabetes diagnosed by doctor	0.6	0.9	1.5	0.5	1.2
Osteoarthritis (self-reported)	0.6	0.8	1.0	0.8	1.0
Ever taken oral contraceptive pill	0.6	0.7	0.9	0.7	1.0
Basal metabolic rate	0.6	3.5	3.6	1.9	1.9
Verbal and Numeric Reasoning (VNR)	0.5	1.2	1.8	0.9	1.3
Blood Red Count	0.5	4.4	6.4	-1.6	-2.5
Allergy or Eczema	0.5	1.2	2.0	-1.4	-0.6
Hypothyroidism (self reported)	0.5	1.1	1.3	-1.1	-1.0
Alcohol usually taken with meals	0.5	0.8	0.9	0.9	0.9
Diabetes (self-reported)	0.5	0.8	1.2	0.6	1.1
Medication: Allopurinol	0.5	0.7	1.3	0.1	-1.1
Whole body fat-free mass	0.5	2.8	3.0	1.7	1.6
Handedness (chirality/laterality): Left-handed	0.5	0.6	0.8	0.9	0.6
Whole body water mass	0.5	3.0	3.2	1.8	1.7
Financial situation satisfaction	0.5	0.6	0.8	-0.6	-0.9
Age started oral contraceptive pill	0.5	0.6	0.7	-0.8	-0.7
Depressed Affect (Nagel 2018)	0.4	0.9	1.0	-0.9	-1.0
Schizophrenia (2014)	0.4	0.8	1.2	0.6	1.1
Severe depression (siblings)	0.4	0.4	0.6	-0.5	-0.8
Current tobacco smoking	0.4	0.7	1.3	0.3	1.2
Hayfever, allergic rhinitis or eczema	0.4	0.8	1.3	-1.1	-0.4
Nervous feelings	0.4	0.7	1.2	-0.5	-1.1
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	0.7	0.8	0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.7	1.3	0.3	1.1
Eye problems/disorders: None of the above	0.4	0.5	0.7	0.5	0.8
Emphysema/chronic bronchitis	0.4	0.5	0.5	0.7	0.7
Whole body fat mass	0.4	1.9	3.0	0.9	1.7
Age at last live birth	0.4	0.6	1.1	1.0	0.4
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	0.9	0.9	0.3
Commuting to job workplace: Car/motor vehicle	0.4	0.5	0.6	0.6	0.8
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	0.5	0.7	0.6
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	0.7	-0.7	-0.9
Guilty feelings	0.4	0.6	1.0	-1.0	-0.5
Leg fat mass (left)	0.4	1.5	2.3	0.9	1.5
Crohns Disease (2012)	0.3	0.4	0.7	0.4	0.9
Mean Putamen Volume	0.3	0.3	0.5	-0.4	-0.7
LDL Cholesterol	0.3	0.6	0.9	-0.9	-0.5
Type 2 Diabetes (T2D) (2018)	0.3	0.5	0.9	0.2	1.0
Frequency of depressed mood in last 2 weeks	0.3	0.5	0.9	1.0	0.1
Medication for hormone replacement therapy	0.3	0.3	0.6	0.1	0.8
Diabetes (father)	0.3	0.4	0.4	0.7	0.6
Qualifications: CSEs or equivalent	0.3	0.4	0.4	0.7	0.6
Trunk fat mass	0.3	1.2	1.9	0.7	1.4
Mouth/teeth dental problems	0.3	0.5	0.5	-0.7	-0.7
Fluid intelligence score	0.3	0.6	1.2	0.1	1.1
Mouth/teeth dental problems: Dentures	0.3	0.6	0.9	0.5	1.0
Trunk predicted mass	0.3	1.5	1.6	1.3	1.2
Exposure to tobacco smoke at home	0.3	0.3	0.6	-0.1	0.8
Arm fat-free mass (right)	0.3	1.7	1.8	1.2	1.4
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	0.4	0.6	0.5
Age at first live birth	0.3	0.6	0.9	1.0	0.6
Mouth/teeth dental problems: Loose teeth	0.3	0.3	0.4	0.6	0.5
Leg fat mass (right)	0.3	1.3	2.1	0.8	1.4
Suffer from ‘nerves’	0.3	0.4	0.7	0.8	0.4
Knee pain experienced in last month	0.3	0.5	1.0	-0.1	1.0
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	1.1	1.1	-0.1
Average weekly red wine intake	0.3	0.4	0.4	-0.7	-0.6
Friendships satisfaction	0.3	0.4	0.5	0.6	0.7
Breast cancer (self-reported)	0.3	0.3	0.3	-0.6	-0.6
Supplements: Fish oil (including cod liver oil)	0.3	0.4	0.7	0.4	0.8
Bipolar Disorder (2018)	0.2	0.3	0.6	-0.3	-0.7
Depression (Nagel 2018)	0.2	0.2	0.4	0.1	-0.7
Intelligence (Savage-Jansen 2018)	0.2	0.5	0.7	0.5	0.8
Worry (Nagel 2018)	0.2	0.4	0.5	-0.6	-0.7
Body Mass Index (BMI) (2010)	0.2	0.3	0.3	0.6	0.6
Rheumatoid Arthritis	0.2	0.2	0.4	0.0	-0.7
Ulcerative Colitis	0.2	0.2	0.5	-0.7	0.1
Tanning	0.2	2.8	3.2	-1.8	-1.6
Vitamin and mineral supplements	0.2	0.3	0.4	-0.5	-0.6
Relative age voice broke	0.2	0.2	0.4	0.1	0.7
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.4	-0.6	0.1
Number of incorrect matches in round	0.2	0.3	0.3	-0.5	-0.6
Past tobacco smoking	0.2	0.3	0.5	-0.3	-0.7
Trunk fat-free mass	0.2	1.4	1.4	1.2	1.1
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	0.7	-0.1	-0.8
Happiness	0.2	0.3	0.4	0.6	0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.5	0.9	-0.1	-1.0
Qualifications: College or University degree	0.2	0.7	1.1	-0.5	-1.1
Arm predicted mass (right)	0.2	0.8	0.9	0.8	1.0
Had major operations	0.2	0.2	0.5	0.0	0.7
Mood swings	0.2	0.3	0.3	0.6	0.5
Smoking status: Current	0.2	0.3	0.6	-0.1	0.8
Medication: Paracetamol	0.2	0.4	0.5	-0.5	-0.7
Ever smoked	0.2	0.3	0.5	-0.4	0.7
Arm fat-free mass (left)	0.2	1.0	1.1	1.0	1.0
Heart disease (siblings)	0.2	0.2	0.3	0.4	0.5
Arm predicted mass (left)	0.2	0.9	0.9	0.9	1.0
Schizophrenia (2018)	0.1	0.3	0.6	0.1	0.7
Alzheimer’s Disease (including proxy)	0.1	0.2	0.3	-0.5	0.3
Fasting Glucose	0.1	0.2	0.3	-0.5	-0.1
Relative age of first facial hair	0.1	0.2	0.5	-0.1	0.7
Ever had hysterectomy (womb removed)	0.1	0.1	0.2	0.4	-0.3
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	0.2	0.2	-0.4
Medication: Metformin	0.1	0.1	0.2	0.1	0.5
Trunk fat percentage	0.1	0.4	0.8	0.1	0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.2	0.1	-0.4
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.1	0.3	-0.4
Had menopause	0.1	0.1	0.1	-0.3	-0.3
Allergy	0.1	0.2	0.3	0.6	-0.3
Pain all over the body in last month	0.1	0.1	0.1	0.3	-0.2
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.2	-0.4	0.3
Impedance of arm (right)	0.1	0.7	0.9	-0.7	-0.9
Time employed in main current job	0.1	0.1	0.2	0.2	0.4
Forced expiratory volume in 1-second (FEV1)	0.1	0.3	0.4	-0.5	-0.6
Qualifications: A levels/AS levels or equivalent	0.1	0.3	0.4	0.5	0.7
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.2	0.4	-0.1
Birth weight of first child	0.1	0.2	0.4	-0.1	-0.6
Loud music exposure frequency	0.1	0.1	0.2	-0.3	0.4
Medication: Paracetamol	0.1	0.1	0.3	-0.5	-0.1
Gout (self-reported)	0.1	0.1	0.1	0.4	-0.3
Body fat percentage	0.1	0.5	1.0	0.0	1.0
Leg fat percentage (right)	0.1	0.3	0.3	-0.5	0.5
Number of full brothers	0.1	0.1	0.2	0.4	0.2
Worry too long after embarrassment	0.1	0.2	0.4	-0.0	0.6
Health satisfaction	0.1	0.1	0.3	0.1	-0.5
Comparative height size at age 10	0.1	0.7	0.7	0.8	0.8
Illness, injury, bereavement, stress in last 2 years	0.1	0.2	0.3	-0.5	0.2
Commuting to job workplace: Walk	0.1	0.1	0.1	0.1	0.3
Wears glasses or contact lenses	0.1	0.1	0.2	-0.5	-0.1
Mother’s age at death	0.1	0.1	0.2	0.2	-0.5
Eye problems/disorders: Glaucoma	0.1	0.1	0.2	-0.4	0.1
Leg fat percentage (left)	0.1	0.2	0.2	-0.5	0.5
Average weekly beer plus cider intake	0.1	0.1	0.3	0.1	0.5
Unable to work because of sickness or disability	0.1	0.1	0.2	0.4	0.1
Myopia	0.1	0.2	0.4	-0.6	0.0
Bipolar Disorder or Schizophrenia	0.0	0.0	0.0	-0.1	0.2
Neuroticism (Nagel 2018)	0.0	0.0	0.1	-0.2	-0.1
Crohns Disease (2017)	0.0	0.1	0.1	0.1	0.4
Irritable Bowel Disease (IBD)	0.0	0.1	0.2	-0.3	0.4
Ulcerative Colitis (UC)	0.0	0.0	0.0	-0.2	0.1
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0
Neuroticism (2016)	0.0	0.0	0.0	0.1	0.2
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0
Blood White Count	0.0	0.3	0.4	-0.4	0.6
Height	0.0	0.5	0.6	0.8	-0.6
Lung FVC	0.0	0.0	0.0	-0.2	-0.2
Hair Pigment	0.0	0.2	0.4	-0.3	-0.6
Average weekly spirits intake	0.0	0.1	0.1	0.3	-0.2
Pack years adult smoking proportion	0.0	0.0	0.1	0.3	0.1
Townsend deprivation index at recruitment	0.0	0.1	0.1	0.1	0.3
Fed-up feelings	0.0	0.0	0.1	-0.2	0.1
Serious illness, injury or assault to yourself	0.0	0.0	0.1	-0.1	-0.3
Forced vital capacity (FVC)	0.0	0.1	0.1	-0.4	-0.3
Financial difficulties in last 2 years	0.0	0.0	0.0	0.2	0.1
Neuroticism score	0.0	0.0	0.0	0.1	0.1
Hip circumference	0.0	0.1	0.2	0.0	0.4
Worrier / anxious feelings	0.0	0.0	0.0	0.2	0.1
Pulse rate	0.0	0.0	0.0	-0.1	-0.0
Illnesses of mother	0.0	0.1	0.1	0.1	0.3
Impedance of arm (left)	0.0	0.1	0.2	-0.3	-0.4
Standing height	0.0	0.1	0.1	0.3	-0.3
Tense / ‘highly strung’	0.0	0.1	0.1	-0.0	0.3
Mouth/teeth dental problems: Bleeding gums	0.0	0.1	0.1	-0.2	-0.2
Forced vital capacity (FVC), Best measure	0.0	0.2	0.3	-0.0	-0.6
Comparative body size at age 10	0.0	0.1	0.1	-0.2	-0.2
Neck or shoulder pain in last month	0.0	0.0	0.0	-0.2	0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.0	0.0	0.0	0.1	0.0
Miserableness	0.0	0.0	0.1	-0.2	-0.1
Alcohol drinker status: Never	0.0	0.0	0.0	0.2	-0.2
Pain experienced in last month	0.0	0.0	0.0	0.2	0.1
Basal cell carcinoma (self-reported)	0.0	0.0	0.0	-0.0	-0.1
Pack years of smoking	0.0	0.1	0.1	-0.2	-0.3

Hub : Genes

CD164L2

Models

Trait associations