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chr10:63,856,856-65,606,229

Best TWAS P=9.91e-13 · Best GWAS P=6.7e-12 conditioned to 0.328

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Skin Sun Exposed Lower leg	NRBF2	0.06	0.01	lasso	3	0.00	4.0e-01	-5.9	7.1	9.9e-13	-0.68	0.08	0.15	TRUE
3	GTEx	Muscle Skeletal	RP11-436D10.3	0.08	0.04	enet	13	0.06	3.2e-06	-6.8	7.0	1.9e-12	-0.87	0.00	1.00	TRUE
11	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	NRBF2	0.09	0.02	enet	6	0.04	1.4e-05	4.4	5.7	1.0e-08	-0.03	0.01	0.98	TRUE
10	The Cancer Genome Atlas	Lung Adenocarcinoma	ADO	0.14	0.05	blup	53	0.05	3.8e-06	-5.9	6.8	8.3e-12	-0.85	0.01	0.99	FALSE
13	The Cancer Genome Atlas	Thyroid Carcinoma	ADO	0.12	0.10	lasso	5	0.09	5.2e-09	-6.8	6.7	1.7e-11	-0.97	0.00	1.00	FALSE
12	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	ADO	0.06	0.04	blup	55	0.01	1.4e-01	-6.8	6.0	1.7e-09	-0.84	0.00	0.86	FALSE
2	GTEx	Muscle Skeletal	ADO	0.15	0.16	lasso	8	0.16	1.1e-15	5.4	5.9	3.5e-09	-0.76	0.77	0.23	FALSE
8	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ADO	0.10	0.03	enet	6	0.06	4.6e-07	5.1	5.6	2.7e-08	-0.79	0.00	0.99	FALSE
6	ROSMAP	Brain Pre-frontal Cortex	ADO	0.06	0.04	lasso	2	0.06	3.1e-08	-6.8	5.5	3.1e-08	-0.89	0.00	1.00	FALSE
5	GTEx	Testis	ADO	0.21	0.23	lasso	7	0.22	6.6e-10	5.4	-5.5	4.3e-08	0.74	0.68	0.32	FALSE
9	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	NRBF2	0.10	0.06	lasso	7	0.08	3.5e-09	5.0	5.2	1.6e-07	-0.04	0.00	0.99	FALSE
1	GTEx	Brain Cortex	NRBF2	0.30	0.26	enet	24	0.21	1.4e-06	5.1	5.2	1.9e-07	-0.06	0.92	0.01	FALSE
7	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	NRBF2	0.04	0.04	enet	5	0.03	1.3e-04	-4.7	5.2	2.4e-07	-0.06	0.01	0.93	FALSE