TWAS
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Traits
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High blood pressure
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chr10:115,244,596-116,689,519
Best TWAS P=2.31e-13 · Best GWAS P=1.67e-21 conditioned to 1.56e-09
115.2M
115.4M
115.6M
115.8M
116M
116.2M
116.4M
116.6M
0
5
10
15
20
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
ADRB1
0.16
0.03
enet
31
0.07
4.1e-08
-9.5
7.3
2.3e-13
-0.60
0.00
0.98
TRUE
3
The Cancer Genome Atlas
Lung Adenocarcinoma
C10orf118
0.03
0.01
blup
42
0.02
1.9e-03
-2.9
5.7
1.5e-08
0.07
0.02
0.39
TRUE
1
ROSMAP
Brain Pre-frontal Cortex
TDRD1
0.06
0.02
bslmm
509
0.02
1.4e-03
-2.6
-5.3
1.5e-07
0.29
0.75
0.01
TRUE