Best TWAS P=6.94e-08 · Best GWAS P=2.36e-09 conditioned to 0.00719
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Cerebellar Hemisphere | HSD17B12 | 0.50 | 0.41 | enet | 33 | 0.29 | 3.0e-08 | 4.3 | -5.3 | 1.0e-07 | 0.72 | 0.67 | 0.32 | FALSE |
2 | GTEx | Whole Blood | RP11-613D13.5 | 0.06 | 0.01 | lasso | 4 | 0.00 | 1.2e-01 | -5.4 | -5.4 | 6.9e-08 | 0.83 | 0.04 | 0.60 | TRUE |