TWAS
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Traits
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Traits
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High blood pressure
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chr11:42,881,882-44,596,817
Best TWAS P=6.94e-08 · Best GWAS P=2.36e-09 conditioned to 0.00719
42.8M
43M
43.2M
43.4M
43.6M
43.8M
44M
44.2M
44.4M
44.6M
0
2
4
6
8
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Whole Blood
RP11-613D13.5
0.06
0.01
lasso
4
0.00
1.2e-01
-5.4
-5.4
6.9e-08
0.83
0.04
0.60
TRUE
1
GTEx
Brain Cerebellar Hemisphere
HSD17B12
0.50
0.41
enet
33
0.29
3.0e-08
4.3
-5.3
1.0e-07
0.72
0.67
0.32
FALSE