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chr11:64,721,908-66,333,072

Best TWAS P=7.35e-11 · Best GWAS P=5.74e-12 conditioned to 4.33e-06

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	The Cancer Genome Atlas	Breast Invasive Carcinoma	RNASEH2C	0.05	0.00	blup	32	0.02	1.1e-04	1.2	-6.5	7.4e-11	0.42	0.00	0.80	TRUE
2	GTEx	Nerve Tibial	SIPA1	0.17	0.01	enet	19	0.06	6.8e-05	-5.1	6.0	1.9e-09	-0.42	0.07	0.79	FALSE
3	ROSMAP	Brain Pre-frontal Cortex	CTSW	0.06	0.03	bslmm	328	0.03	3.6e-05	2.8	-6.0	1.9e-09	0.46	0.47	0.24	FALSE
7	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SIPA1	0.04	0.00	blup	43	0.02	6.2e-03	-5.2	5.7	1.1e-08	-0.59	0.00	0.39	FALSE
5	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SIPA1	0.06	0.04	blup	43	0.05	4.6e-06	-3.6	5.4	6.1e-08	-0.52	0.02	0.93	FALSE
1	GTEx	Cells Transformed fibroblasts	SIPA1	0.19	0.00	enet	30	0.05	2.5e-04	4.4	5.4	8.1e-08	-0.48	0.05	0.82	FALSE
6	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	RNASEH2C	0.15	0.05	blup	32	0.05	3.1e-06	1.2	-5.3	9.0e-08	0.48	0.36	0.02	FALSE