Best TWAS P=4.7e-10 · Best GWAS P=1.08e-10 conditioned to 0.0135
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellum | RP11-819C21.1 | 0.18 | 0.08 | enet | 2 | 0.02 | 8.8e-02 | 6.1 | -5.3 | 1.2e-07 | -0.76 | 0.04 | 0.66 | FALSE |
| 2 | GTEx | Breast Mammary Tissue (Male) | RP11-819C21.1 | 0.15 | -0.01 | lasso | 1 | -0.01 | 7.0e-01 | 6.1 | -6.1 | 1.2e-09 | -0.80 | 0.04 | 0.23 | FALSE |
| 3 | GTEx | Heart Left Ventricle | CWF19L2 | 0.10 | 0.07 | lasso | 4 | 0.05 | 1.4e-03 | 4.3 | 5.2 | 1.5e-07 | 0.69 | 0.12 | 0.82 | FALSE |
| 4 | GTEx | Muscle Skeletal | CWF19L2 | 0.08 | 0.05 | lasso | 3 | 0.05 | 1.1e-05 | 6.1 | 6.2 | 4.7e-10 | 0.80 | 0.01 | 0.99 | TRUE |
| 5 | GTEx | Testis | CWF19L2 | 0.20 | 0.09 | lasso | 6 | 0.09 | 1.0e-04 | 6.1 | 5.9 | 4.0e-09 | 0.72 | 0.07 | 0.90 | FALSE |
| 6 | The Cancer Genome Atlas | Colon Adenocarcinoma | CWF19L2 | 0.11 | 0.01 | blup | 105 | 0.02 | 3.0e-02 | -2.3 | 5.4 | 6.2e-08 | 0.62 | 0.03 | 0.06 | FALSE |