[Hub]/) : Traits : High blood pressure : ← →

chr11:110,721,187-112,491,227

Best TWAS P=3.11e-10 · Best GWAS P=3.11e-10 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex C11orf1 0.06 0.06 lasso 5 0.05 4.4e-07 5.6 -5.6 2.5e-08 -0.76 0.23 0.77 FALSE
2 GTEx Brain Putamen basal ganglia LAYN 0.24 0.12 lasso 7 0.13 6.2e-04 4.9 -5.4 6.5e-08 -0.81 0.11 0.48 FALSE
3 GTEx Esophagus Mucosa SIK2 0.13 0.03 lasso 4 0.02 2.2e-02 5.1 5.7 1.6e-08 0.91 0.10 0.68 FALSE
4 GTEx Skin Sun Exposed Lower leg CRYAB 0.07 0.04 lasso 10 0.02 1.3e-02 5.6 5.6 1.9e-08 0.73 0.10 0.79 FALSE
5 GTEx Skin Sun Exposed Lower leg C11orf1 0.06 0.05 lasso 2 0.02 9.6e-03 5.6 -5.6 2.1e-08 -0.73 0.16 0.66 FALSE
6 GTEx Testis PPP2R1B 0.34 0.21 lasso 10 0.36 1.5e-16 6.0 -5.5 2.9e-08 -0.81 0.07 0.93 FALSE
7 The Cancer Genome Atlas Breast Invasive Carcinoma LAYN 0.02 0.03 blup 33 0.03 3.7e-06 5.1 5.5 3.0e-08 0.80 0.06 0.94 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma SIK2 0.04 0.01 blup 35 0.01 6.7e-03 6.3 5.3 9.9e-08 0.95 0.01 0.95 FALSE
9 The Cancer Genome Atlas Colon Adenocarcinoma C11orf1 0.11 0.07 enet 2 0.08 3.4e-05 5.1 -5.2 2.3e-07 -0.71 0.00 0.92 FALSE
10 The Cancer Genome Atlas Pancreatic Adenocarcinoma LAYN 0.13 0.07 enet 8 0.07 9.9e-04 4.9 5.5 2.9e-08 0.68 0.02 0.72 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma SIK2 0.05 0.06 lasso 1 0.05 2.6e-06 6.3 6.3 3.1e-10 1.00 0.00 1.00 TRUE