Best TWAS P=6.39e-12 · Best GWAS P=3.66e-10 conditioned to 0.0637
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellar Hemisphere | AGT | 0.67 | 0.50 | enet | 12 | 0.40 | 3.4e-11 | 6.2 | -6.2 | 7.5e-10 | -0.98 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Brain Cerebellum | AGT | 0.60 | 0.40 | lasso | 6 | 0.36 | 1.4e-11 | 6.2 | 6.4 | 2.0e-10 | 0.93 | 0.00 | 1.00 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | AGT | 0.07 | 0.02 | enet | 12 | 0.04 | 1.8e-05 | 5.3 | 6.9 | 6.4e-12 | 0.73 | 0.02 | 0.97 | TRUE |
| 4 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | AGT | 0.11 | 0.05 | blup | 125 | 0.04 | 1.4e-03 | 5.6 | 5.6 | 1.9e-08 | 0.68 | 0.02 | 0.85 | FALSE |