[Hub]/) : Traits : High blood pressure :

chr12:47,737,273-49,444,545

Best TWAS P=6.3e-09 · Best GWAS P=1.33e-09 conditioned to 0.246

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SENP1 0.05 0.02 blup 555 0.04 1.7e-05 5.4 -5.5 4.2e-08 0.12 0.23 0.77 TRUE
2 GTEx Lung ZNF641 0.08 0.10 lasso 2 0.08 8.0e-07 5.3 5.2 1.6e-07 -0.07 0.01 0.98 FALSE
3 GTEx Nerve Tibial ZNF641 0.14 0.11 lasso 4 0.08 2.3e-06 5.1 5.3 1.2e-07 -0.07 0.02 0.98 FALSE
4 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma HDAC7 0.05 0.02 blup 85 0.01 7.5e-03 -5.8 -5.8 6.3e-09 0.82 0.00 0.97 TRUE
5 The Cancer Genome Atlas Thyroid Carcinoma ZNF641 0.11 0.12 enet 10 0.12 5.2e-12 5.2 5.5 4.4e-08 -0.08 0.00 1.00 FALSE