Best TWAS P=3.4e-08 · Best GWAS P=3.45e-08 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | CAND1 | 0.07 | 0.05 | lasso | 4 | 0.06 | 2.3e-07 | 5.4 | -5.5 | 3.4e-08 | -0.97 | 0.01 | 0.99 | TRUE |
2 | GTEx | Adipose Subcutaneous | CAND1 | 0.11 | 0.06 | lasso | 6 | 0.05 | 6.4e-05 | 5.5 | -5.5 | 4.1e-08 | -0.95 | 0.02 | 0.98 | FALSE |
3 | GTEx | Artery Tibial | CAND1 | 0.07 | 0.03 | lasso | 3 | 0.03 | 1.7e-03 | 5.4 | -5.3 | 1.4e-07 | -0.96 | 0.03 | 0.96 | FALSE |
4 | GTEx | Lung | CAND1 | 0.11 | 0.00 | lasso | 5 | 0.00 | 2.1e-01 | 5.0 | -5.2 | 2.5e-07 | -0.89 | 0.02 | 0.94 | FALSE |