TWAS
hub
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Usage
Models
Genes
Traits
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Traits
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High blood pressure
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chr12:69,057,879-70,476,863
Best TWAS P=1.24e-08 · Best GWAS P=6.81e-08 conditioned to 1
69M
69.2M
69.4M
69.6M
69.8M
70M
70.2M
70.4M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Pituitary
YEATS4
0.29
0.05
lasso
7
0.08
5.3e-03
5.2
5.7
1.2e-08
0.98
0.02
0.93
TRUE
1
GTEx
Artery Aorta
YEATS4
0.25
0.12
enet
11
0.21
5.0e-12
5.0
5.7
1.5e-08
0.86
0.02
0.98
FALSE
3
The Cancer Genome Atlas
Breast Invasive Carcinoma
YEATS4
0.07
0.06
blup
73
0.06
4.2e-13
4.8
5.5
3.4e-08
0.93
0.04
0.96
FALSE
4
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
YEATS4
0.26
0.18
enet
17
0.29
4.9e-33
-2.9
5.2
2.0e-07
0.69
0.85
0.04
FALSE