Best TWAS P=1.24e-08 · Best GWAS P=6.81e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | YEATS4 | 0.25 | 0.12 | enet | 11 | 0.21 | 5.0e-12 | 5.0 | 5.7 | 1.5e-08 | 0.86 | 0.02 | 0.98 | FALSE |
| 2 | GTEx | Pituitary | YEATS4 | 0.29 | 0.05 | lasso | 7 | 0.08 | 5.3e-03 | 5.2 | 5.7 | 1.2e-08 | 0.98 | 0.02 | 0.93 | TRUE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | YEATS4 | 0.07 | 0.06 | blup | 73 | 0.06 | 4.2e-13 | 4.8 | 5.5 | 3.4e-08 | 0.93 | 0.04 | 0.96 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | YEATS4 | 0.26 | 0.18 | enet | 17 | 0.29 | 4.9e-33 | -2.9 | 5.2 | 2.0e-07 | 0.69 | 0.85 | 0.04 | FALSE |