Best TWAS P=5.33e-16 · Best GWAS P=3.81e-25 conditioned to 2.55e-13
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Tibial | ATP2B1 | 0.08 | 0.01 | enet | 10 | 0.03 | 0.0035 | -9.5 | -8.1 | 5.3e-16 | 0.37 | 0.12 | 0.55 | TRUE |
2 | GTEx | Prostate | POC1B | 0.25 | 0.00 | enet | 37 | 0.01 | 0.1640 | -9.9 | 5.8 | 7.6e-09 | -0.54 | 0.03 | 0.58 | FALSE |
3 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | LOC338758 | 0.14 | 0.00 | enet | 6 | 0.01 | 0.0619 | 2.1 | -6.2 | 5.3e-10 | 0.31 | 0.00 | 0.18 | TRUE |