TWAS
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Traits
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High blood pressure
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chr15:67,138,238-68,789,191
Best TWAS P=8.94e-08 · Best GWAS P=1.68e-08 conditioned to 0.0326
67.2M
67.4M
67.6M
67.8M
68M
68.2M
68.4M
68.6M
68.8M
0
2
4
6
8
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Muscle Skeletal
MAP2K5
0.08
0.03
lasso
6
0.05
1.9e-05
4.6
5.3
8.9e-08
0.83
0.03
0.97
TRUE
1
GTEx
Heart Atrial Appendage
MAP2K5
0.16
0.08
lasso
5
0.16
1.3e-07
-4.3
5.2
1.5e-07
0.79
0.10
0.90
FALSE