Best TWAS P=8.94e-08 · Best GWAS P=1.68e-08 conditioned to 0.0326
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Heart Atrial Appendage | MAP2K5 | 0.16 | 0.08 | lasso | 5 | 0.16 | 1.3e-07 | -4.3 | 5.2 | 1.5e-07 | 0.79 | 0.10 | 0.90 | FALSE |
| 2 | GTEx | Muscle Skeletal | MAP2K5 | 0.08 | 0.03 | lasso | 6 | 0.05 | 1.9e-05 | 4.6 | 5.3 | 8.9e-08 | 0.83 | 0.03 | 0.97 | TRUE |