[Hub]/) : Traits : High blood pressure : ← →

chr15:40,360,741-42,749,023

Best TWAS P=4.57e-11 · Best GWAS P=2.87e-11 conditioned to 0.0986

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex EXD1 0.04 0.04 lasso 3 0.04 8.1e-06 6.0 -5.9 3.6e-09 -0.94 0.05 0.94 FALSE
2 GTEx Brain Cortex GCHFR 0.25 0.04 enet 15 0.05 1.4e-02 5.1 -5.4 8.3e-08 -0.77 0.04 0.72 FALSE
3 GTEx Colon Sigmoid NDUFAF1 0.15 0.06 lasso 4 0.06 5.2e-03 5.5 -6.1 8.7e-10 -0.70 0.16 0.59 FALSE
4 GTEx Esophagus Mucosa NDUFAF1 0.25 0.18 enet 26 0.24 4.3e-16 5.5 -5.2 2.0e-07 -0.60 0.92 0.08 FALSE
5 GTEx Esophagus Mucosa CHP1 0.19 0.10 lasso 7 0.09 1.4e-06 5.5 -5.8 7.0e-09 -0.94 0.02 0.98 FALSE
6 GTEx Lung OIP5-AS1 0.09 0.08 enet 14 0.12 2.8e-09 6.2 5.6 2.0e-08 0.88 0.02 0.98 FALSE
7 GTEx Skin Not Sun Exposed Suprapubic NDUFAF1 0.16 0.06 lasso 3 0.07 1.7e-04 5.5 -5.7 1.5e-08 -0.50 0.09 0.13 FALSE
8 GTEx Skin Sun Exposed Lower leg CHP1 0.06 0.04 enet 9 0.04 3.1e-04 6.2 -6.6 4.6e-11 -0.90 0.03 0.95 TRUE
9 NTR Blood INO80 0.02 0.02 enet 8 0.03 2.8e-09 5.2 -5.4 7.3e-08 -0.84 0.55 0.45 FALSE
10 YFS Blood MGA 0.01 0.00 blup 454 0.00 7.1e-02 5.9 6.0 1.9e-09 0.69 0.02 0.82 FALSE
11 The Cancer Genome Atlas Breast Invasive Carcinoma CHP 0.01 0.01 blup 54 0.01 1.4e-02 6.6 -6.2 5.5e-10 -0.92 0.01 0.90 FALSE