Best TWAS P=1.42e-07 · Best GWAS P=4.98e-07 conditioned to 0.373
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellum | PDPR | 0.23 | 0.06 | enet | 20 | 0.11 | 3.7e-04 | -4.1 | -5.2 | 1.9e-07 | -0.58 | 0.03 | 0.30 | FALSE |
| 2 | GTEx | Colon Sigmoid | PDXDC2P | 0.30 | 0.16 | enet | 13 | 0.14 | 8.8e-06 | 4.2 | -5.3 | 1.4e-07 | -0.82 | 0.04 | 0.88 | FALSE |
| 3 | GTEx | Esophagus Gastroesophageal Junction | RP11-296I10.6 | 0.26 | 0.22 | enet | 15 | 0.20 | 7.9e-08 | -4.2 | -5.3 | 1.4e-07 | -0.87 | 0.05 | 0.88 | TRUE |
| 4 | GTEx | Stomach | RP11-296I10.6 | 0.24 | 0.15 | enet | 14 | 0.16 | 4.5e-08 | -4.2 | -5.2 | 2.2e-07 | -0.70 | 0.09 | 0.80 | FALSE |
| 5 | GTEx | Thyroid | PDXDC2P | 0.41 | 0.27 | lasso | 10 | 0.30 | 5.0e-23 | 4.5 | -5.2 | 1.9e-07 | -0.87 | 0.03 | 0.93 | FALSE |