TWAS
hub
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Usage
Models
Genes
Traits
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Traits
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High blood pressure
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chr2:26,223,547-27,689,899
Best TWAS P=1.71e-08 · Best GWAS P=2.01e-33 conditioned to 1.31e-24
26.2M
26.4M
26.6M
26.8M
27M
27.2M
27.4M
27.6M
0
10
20
30
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
METSIM
Adipose
SLC35F6
0.04
0.01
blup
362
0.02
1.1e-03
3.1
5.6
1.7e-08
0.49
0.11
0.40
TRUE
3
ROSMAP
Brain Pre-frontal Cortex
KCNK3
0.24
0.15
lasso
3
0.15
6.5e-19
5.3
-5.2
2.3e-07
-0.35
1.00
0.00
TRUE
1
GTEx
Skin Sun Exposed Lower leg
SLC35F6
0.10
0.04
lasso
4
0.05
4.2e-05
-4.3
5.2
1.9e-07
0.38
0.45
0.08
FALSE