Best TWAS P=1.71e-08 · Best GWAS P=2.01e-33 conditioned to 1.31e-24
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Sun Exposed Lower leg | SLC35F6 | 0.10 | 0.04 | lasso | 4 | 0.05 | 4.2e-05 | -4.3 | 5.2 | 1.9e-07 | 0.38 | 0.45 | 0.08 | FALSE |
| 2 | METSIM | Adipose | SLC35F6 | 0.04 | 0.01 | blup | 362 | 0.02 | 1.1e-03 | 3.1 | 5.6 | 1.7e-08 | 0.49 | 0.11 | 0.40 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | KCNK3 | 0.24 | 0.15 | lasso | 3 | 0.15 | 6.5e-19 | 5.3 | -5.2 | 2.3e-07 | -0.35 | 1.00 | 0.00 | TRUE |