Best TWAS P=6.81e-10 · Best GWAS P=3.59e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | PRKD3 | 0.08 | 0.04 | lasso | 3 | 0.04 | 3.0e-05 | 5.8 | 6.2 | 6.8e-10 | 0.97 | 0.01 | 0.99 | TRUE |
| 2 | GTEx | Lung | QPCT | 0.15 | 0.01 | lasso | 7 | 0.00 | 2.8e-01 | 5.1 | 5.2 | 2.3e-07 | 0.86 | 0.02 | 0.75 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | PRKD3 | 0.09 | 0.08 | lasso | 2 | 0.07 | 6.4e-09 | 5.8 | 5.8 | 6.1e-09 | 0.99 | 0.00 | 1.00 | FALSE |