Best TWAS P=9.26e-10 · Best GWAS P=1.09e-08 conditioned to 1.02e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | AC016747.3 | 0.14 | 0.13 | enet | 15 | 0.16 | 7.6e-09 | -4.2 | 5.2 | 1.6e-07 | 0.09 | 0.49 | 0.50 | FALSE |
| 2 | GTEx | Brain Cerebellar Hemisphere | AHSA2 | 0.35 | 0.22 | enet | 12 | 0.38 | 7.8e-11 | 4.7 | 5.3 | 9.1e-08 | 0.10 | 0.33 | 0.64 | FALSE |
| 3 | GTEx | Brain Cerebellum | KIAA1841 | 0.10 | 0.05 | lasso | 3 | 0.05 | 1.2e-02 | 5.6 | 5.4 | 5.2e-08 | 0.06 | 0.04 | 0.88 | FALSE |
| 4 | GTEx | Brain Nucleus accumbens basal ganglia | KIAA1841 | 0.17 | 0.16 | lasso | 3 | 0.18 | 1.7e-05 | 4.7 | 6.1 | 9.3e-10 | 0.07 | 0.08 | 0.80 | TRUE |
| 5 | GTEx | Colon Transverse | AC010733.5 | 0.12 | 0.00 | lasso | 6 | 0.00 | 4.5e-01 | -3.9 | 5.8 | 7.2e-09 | 0.06 | 0.06 | 0.30 | FALSE |
| 6 | GTEx | Heart Left Ventricle | AHSA2 | 0.13 | 0.08 | lasso | 8 | 0.07 | 1.2e-04 | -4.5 | 6.0 | 1.7e-09 | 0.07 | 0.14 | 0.84 | FALSE |
| 7 | GTEx | Stomach | AHSA2 | 0.22 | 0.17 | enet | 21 | 0.24 | 1.0e-11 | -4.5 | 5.2 | 2.5e-07 | 0.07 | 0.53 | 0.46 | FALSE |
| 8 | YFS | Blood | PEX13 | 0.01 | 0.00 | blup | 334 | 0.01 | 6.7e-03 | 4.1 | -5.5 | 3.5e-08 | -0.06 | 0.09 | 0.45 | FALSE |
| 9 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | PEX13 | 0.11 | 0.00 | blup | 40 | 0.03 | 6.6e-02 | 3.5 | -5.3 | 1.1e-07 | -0.01 | 0.01 | 0.25 | FALSE |