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chr1:7,686,056-11,137,778

Best TWAS P=5.66e-14 · Best GWAS P=1.91e-12 conditioned to 0.0996

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
21	METSIM	Adipose	RERE	0.08	0.12	lasso	17	0.13	1.8e-19	-5.6	-7.5	5.7e-14	-0.84	0.50	0.50	TRUE
5	GTEx	Brain Caudate basal ganglia	KIF1B	0.25	0.00	lasso	5	0.02	1.1e-01	4.7	5.7	1.3e-08	-0.03	0.04	0.31	TRUE
10	GTEx	Esophagus Mucosa	RP5-1115A15.1	0.06	0.06	lasso	4	0.05	3.0e-04	6.9	-7.1	1.2e-12	-0.87	0.05	0.88	FALSE
16	GTEx	Skin Not Sun Exposed Suprapubic	RP5-1115A15.1	0.08	0.04	enet	8	0.04	3.0e-03	7.0	-7.0	2.3e-12	-0.97	0.02	0.95	FALSE
20	GTEx	Whole Blood	RERE	0.19	0.15	lasso	4	0.13	2.7e-12	6.9	-7.0	3.1e-12	-0.86	0.03	0.97	FALSE
25	YFS	Blood	RERE	0.09	0.15	lasso	4	0.16	5.7e-49	6.7	-7.0	3.1e-12	-0.86	0.11	0.89	FALSE
30	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	RERE	0.22	0.04	lasso	10	0.08	4.1e-04	6.9	-7.0	3.4e-12	-0.81	0.10	0.72	FALSE
22	NTR	Blood	RERE	0.04	0.04	lasso	8	0.03	2.0e-11	7.0	-6.9	5.6e-12	-0.94	0.02	0.98	FALSE
9	GTEx	Esophagus Mucosa	RERE	0.13	0.16	lasso	3	0.16	7.2e-11	6.9	-6.9	5.7e-12	-0.86	0.03	0.97	FALSE
11	GTEx	Lung	RERE	0.07	0.05	lasso	4	0.05	2.0e-04	6.7	-6.9	6.5e-12	-0.98	0.02	0.97	FALSE
19	GTEx	Thyroid	RP5-1115A15.1	0.09	0.12	lasso	2	0.09	1.5e-07	6.6	-6.8	9.5e-12	-0.85	0.09	0.91	FALSE
12	GTEx	Lung	RP5-1115A15.1	0.05	0.08	lasso	1	0.07	1.0e-05	6.6	-6.6	3.8e-11	-0.86	0.04	0.93	FALSE
26	The Cancer Genome Atlas	Breast Invasive Carcinoma	RERE	0.02	0.03	lasso	2	0.03	4.7e-07	6.7	-6.5	6.7e-11	-0.87	0.08	0.91	FALSE
14	GTEx	Pancreas	RERE	0.11	0.12	lasso	4	0.07	5.9e-04	-5.9	-6.5	8.5e-11	-0.59	0.21	0.41	FALSE
4	GTEx	Adipose Visceral Omentum	RERE	0.22	0.17	lasso	5	0.17	5.2e-09	6.9	-6.4	1.5e-10	-0.86	0.06	0.94	FALSE
27	The Cancer Genome Atlas	Esophageal Carcinoma	RERE	0.10	0.07	blup	154	0.06	5.2e-03	6.2	-6.4	1.5e-10	-0.92	0.04	0.55	FALSE
6	GTEx	Breast Mammary Tissue	RERE	0.19	0.08	enet	10	0.14	8.0e-08	-5.9	-6.3	2.3e-10	-0.73	0.19	0.78	FALSE
23	ROSMAP	Brain Pre-frontal Cortex	RERE	0.15	0.15	lasso	7	0.15	1.5e-18	-5.8	-6.3	2.9e-10	-0.67	0.96	0.04	FALSE
1	CommonMind	Brain Pre-frontal Cortex	SLC45A1	0.04	0.05	enet	9	0.02	1.8e-03	5.3	6.3	3.1e-10	0.75	0.69	0.24	FALSE
17	GTEx	Skin Sun Exposed Lower leg	RERE	0.14	0.05	lasso	8	0.08	4.3e-07	6.9	-6.3	3.3e-10	-0.88	0.04	0.96	FALSE
2	GTEx	Adipose Subcutaneous	RERE	0.20	0.23	lasso	2	0.24	1.7e-19	-5.6	-6.3	4.0e-10	-0.66	0.98	0.02	FALSE
3	GTEx	Adipose Subcutaneous	RP5-1115A15.1	0.14	0.07	enet	20	0.10	2.6e-08	6.6	-6.2	4.7e-10	-0.81	0.06	0.94	FALSE
13	GTEx	Nerve Tibial	RERE	0.12	0.09	enet	16	0.11	5.6e-08	-5.8	-6.1	9.3e-10	-0.59	0.90	0.10	FALSE
18	GTEx	Skin Sun Exposed Lower leg	RP5-1115A15.1	0.07	0.03	enet	13	0.03	1.5e-03	6.9	-6.1	1.4e-09	-0.81	0.05	0.92	FALSE
8	GTEx	Cells Transformed fibroblasts	RERE	0.12	0.08	lasso	4	0.05	6.0e-05	-5.8	-6.0	2.6e-09	-0.60	0.70	0.26	FALSE
24	YFS	Blood	ENO1	0.07	0.06	lasso	7	0.06	5.1e-19	-5.3	6.0	2.6e-09	0.51	0.98	0.02	FALSE
29	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	RERE	0.04	0.02	blup	154	0.02	8.7e-04	6.5	-5.8	7.7e-09	-0.90	0.03	0.89	FALSE
31	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	RERE	0.12	0.01	enet	10	0.03	4.6e-02	6.5	-5.7	1.0e-08	-0.86	0.03	0.62	FALSE
7	GTEx	Breast Mammary Tissue	RP5-1115A15.1	0.10	0.07	lasso	2	0.03	7.0e-03	-5.6	-5.6	2.0e-08	-0.55	0.44	0.33	FALSE
15	GTEx	Skin Not Sun Exposed Suprapubic	RERE	0.12	0.05	lasso	4	0.05	1.3e-03	6.7	-5.6	2.5e-08	-0.81	0.08	0.87	FALSE
28	The Cancer Genome Atlas	Glioblastoma Multiforme	PEX14	0.12	0.00	blup	123	0.05	9.9e-03	4.9	-5.3	9.2e-08	-0.06	0.02	0.64	FALSE