TWAS hub - PEX14

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1510	0.0420	8.5e-07	0.085	NA	0.100	NA	0.076	1.8e-07	NA	1.6e-08	NA	8.6e-07
2	GTEx	Adipose Visceral Omentum	0.1070	0.0430	1.3e-03	0.076	NA	0.040	NA	0.067	9.2e-05	NA	3.9e-03	NA	2.2e-04
3	GTEx	Liver	0.3070	0.1330	9.0e-03	0.018	NA	-0.008	NA	-0.010	1.0e-01	NA	6.2e-01	NA	9.1e-01
4	GTEx	Lung	0.1683	0.0473	2.4e-06	0.124	NA	0.088	NA	0.041	9.6e-10	NA	2.7e-07	NA	3.9e-04
5	GTEx	Vagina	0.7740	0.0890	2.6e-05	-0.009	NA	-0.006	NA	0.009	6.0e-01	NA	4.7e-01	NA	2.0e-01
6	METSIM	Adipose	0.1377	0.0282	0.0e+00	0.170	0.122	0.160	0.082	0.081	1.2e-24	8.8e-18	3.3e-23	3.0e-12	4.4e-12
7	YFS	Blood	0.0197	0.0070	5.5e-05	0.016	0.010	0.012	0.010	0.019	2.8e-06	1.7e-04	7.3e-05	1.8e-04	6.6e-07
8	TCGA	Glioblastoma Multiforme	0.1240	0.0660	8.7e-03	0.000	0.054	0.018	NA	0.022	3.2e-01	9.9e-03	9.1e-02	NA	7.0e-02
9	TCGA	Liver Hepatocellular Carcinoma	0.0820	0.0420	4.6e-03	0.013	0.044	0.046	NA	0.027	7.8e-02	3.8e-03	3.1e-03	NA	1.9e-02
10	TCGA	Prostate Adenocarcinoma	0.0721	0.0423	1.9e-03	-0.003	0.004	0.007	NA	-0.002	9.4e-01	1.0e-01	5.2e-02	NA	7.9e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Breast Cancer	11.4	27.4	69.6	-4.7	-4.8	-4.0	-5.9	6.0	-4.9	-4.8	-8.3	1.0	4.8
Ever had prostate specific antigen (PSA) test	5.8	6.7	18.3	2.0	2.4	1.8	2.7	-2.0	2.7	2.1	4.3	0.7	-3.5
Forced expiratory volume in 1-second (FEV1), predicted	5.3	11.0	17.2	-4.2	-3.9	-4.2	-3.8	-1.2	-3.5	-3.9	-0.8	-3.9	-1.6
Loneliness, isolation	4.0	5.6	8.2	-2.8	-2.4	-2.5	-2.4	-2.9	-2.5	-2.4	-1.2	-2.6	1.1
Breast cancer (self-reported)	3.8	4.5	13.8	2.1	1.7	1.5	2.2	-1.7	2.1	1.8	3.7	0.2	-2.6
Hair/balding pattern: Pattern 2	3.7	4.6	9.8	2.1	2.1	2.3	1.9	2.6	1.9	2.0	-0.2	3.1	2.0
Allergy	3.6	8.2	28.5	-2.8	-2.0	-1.5	-3.0	0.3	-2.3	-2.0	-5.3	-1.4	4.4
Asthma	3.6	7.1	27.0	2.3	1.6	1.1	2.7	-1.7	1.8	1.8	5.2	0.9	-4.3
Hand grip strength (right)	3.5	9.5	30.1	-3.0	-2.1	-1.6	-3.1	0.7	-2.4	-2.3	-5.3	-0.1	5.5
Multivitamins +/- minerals	3.4	4.3	6.1	2.4	2.1	2.2	2.3	-0.9	2.5	2.1	2.2	2.4	0.3
Asthma (self-reported)	3.4	6.8	26.7	2.1	1.5	1.0	2.6	-1.6	1.7	1.6	5.2	0.7	-4.3
Deep venous thrombosis (DVT) (self-reported)	3.1	4.0	10.4	2.1	1.7	1.5	2.3	-1.3	1.8	1.9	3.2	0.9	-2.3
Medication: Metformin	3.0	4.3	8.6	2.9	2.2	2.2	2.9	-0.3	2.0	2.3	1.9	1.4	-0.9
Primary Biliary Cirrhosis	2.9	4.1	7.1	2.5	2.4	2.5	2.7	1.0	2.0	2.4	1.1	1.4	-1.0
Respiratory disease	2.8	6.3	21.2	2.5	1.8	1.2	2.9	-1.4	1.9	2.0	4.6	0.3	-3.6
Chronic bronchitis/emphysema (father)	2.8	3.3	11.2	2.4	1.5	1.2	2.4	0.2	1.7	1.9	3.4	0.1	-0.6
Birth weight	2.8	6.0	9.7	3.0	3.0	3.0	3.1	-1.1	2.5	2.9	1.7	1.8	1.3
Taking other prescription medications	2.7	4.1	14.1	1.0	0.8	0.5	1.8	-2.7	0.7	1.0	3.8	0.4	-3.7
Hayfever/allergic rhinitis (self-reported)	2.7	3.5	6.7	2.3	1.8	1.5	2.4	1.0	1.6	1.7	2.6	1.2	-2.2
Prostate Cancer	2.6	3.6	10.4	1.6	1.8	1.5	1.8	-1.2	2.0	1.5	3.2	0.8	-2.4
Ever had hysterectomy (womb removed)	2.6	2.9	5.1	1.8	1.6	1.7	1.9	1.9	1.7	1.6	1.0	2.2	-1.4
Vitamin and mineral supplements	2.6	3.6	5.8	-2.0	-2.0	-1.9	-2.1	1.1	-2.4	-1.9	-2.4	-1.8	0.1
Happiness	2.6	3.2	7.3	-2.1	-2.0	-2.0	-1.6	-0.1	-2.2	-1.9	-1.1	-2.7	0.0
LDL Cholesterol	2.5	4.0	6.6	2.0	2.5	2.2	2.6	-1.7	2.1	2.5	1.8	0.7	0.1
Mean Putamen Volume	2.3	2.7	6.2	1.1	1.4	1.1	1.9	-2.5	1.0	1.5	1.9	-0.9	-2.1
Average weekly fortified wine intake	2.3	2.7	4.4	-1.8	-2.0	-1.9	-2.1	0.5	-1.8	-1.8	-1.6	-1.4	-0.3
Illnesses of siblings: Diabetes	2.3	2.8	12.5	-1.5	-1.5	-1.6	-1.1	-1.0	-1.1	-1.3	1.7	-0.7	-3.5
Alcohol drinker status: Never	2.3	2.7	4.7	-2.1	-1.8	-2.2	-1.7	-0.0	-1.7	-1.9	0.4	-1.9	-1.1
Hypothyroidism (self reported)	2.2	5.0	11.0	2.1	2.1	2.0	2.8	-1.7	1.9	2.3	3.3	0.4	-2.6
Ever used hormone-replacement therapy (HRT)	2.2	2.8	10.8	2.1	1.4	1.6	1.4	1.2	1.6	1.3	0.6	3.3	-0.1
Hayfever, allergic rhinitis or eczema	2.2	4.7	10.4	2.5	1.7	1.5	2.3	1.2	1.9	1.6	3.2	1.9	-3.0
Trunk fat-free mass	2.2	12.5	21.3	-4.6	-4.3	-4.1	-4.3	-2.4	-4.0	-4.2	-1.3	-2.8	-0.4
Trunk predicted mass	2.2	12.6	21.3	-4.6	-4.3	-4.2	-4.4	-2.3	-4.1	-4.2	-1.3	-2.8	-0.5
Blood clot in the leg (DVT)	2.2	2.9	7.9	1.8	1.4	1.2	1.9	-1.3	1.5	1.5	2.8	0.6	-2.0
Wheeze or whistling in the chest in last year	2.2	3.8	7.0	1.9	1.8	1.7	2.2	-0.9	1.7	2.0	2.5	1.7	-2.6
Whole body water mass	2.2	12.3	20.2	-4.5	-4.2	-4.1	-4.2	-2.8	-3.9	-4.1	-0.8	-3.2	-0.5
Number of self-reported non-cancer illnesses	2.2	3.7	8.8	2.0	1.6	1.5	2.1	-1.1	1.5	1.6	2.7	1.5	-3.0
Lung cancer (father)	2.1	2.4	4.0	1.9	2.0	1.7	2.0	-0.8	1.7	1.7	1.4	0.8	0.6
Standing height	2.1	20.8	32.3	-4.9	-5.2	-5.7	-4.2	-2.8	-4.9	-5.1	1.3	-5.6	-4.1
Glaucoma (self-reported)	2.1	2.4	4.6	-1.7	-2.1	-2.1	-2.0	-0.5	-1.4	-2.0	-0.2	-1.2	-1.0
Whole body fat-free mass	2.1	12.2	20.2	-4.5	-4.1	-4.1	-4.2	-2.8	-3.9	-4.1	-0.9	-3.2	-0.4
Number of children fathered	2.0	2.3	3.7	1.9	1.7	1.5	1.8	-0.7	1.5	1.5	0.7	1.9	-1.2
Medication: Allopurinol	2.0	2.7	4.4	-1.5	-1.6	-1.8	-1.1	-2.1	-1.1	-1.4	1.5	-1.7	-2.1
Leg fat-free mass (right)	2.0	10.9	16.6	-4.1	-3.8	-3.9	-3.9	-2.6	-3.5	-3.8	-0.6	-3.7	-0.3
Leg predicted mass (right)	2.0	10.9	16.6	-4.1	-3.8	-3.9	-3.9	-2.6	-3.5	-3.8	-0.6	-3.7	-0.2
Height	1.9	36.1	54.0	-6.4	-6.8	-7.3	-5.7	-3.0	-6.2	-6.5	1.2	-7.0	-6.9
Supplements: Zinc	1.9	2.1	3.7	1.6	1.9	1.8	1.5	-1.2	1.9	1.9	1.1	-0.1	0.2
Leg fat-free mass (left)	1.9	9.8	15.2	-3.9	-3.6	-3.6	-3.6	-3.0	-3.3	-3.5	-0.1	-3.4	-0.7
Maternal smoking around birth	1.9	2.8	4.9	-2.2	-2.1	-2.0	-2.1	-0.4	-1.7	-2.0	-0.2	-1.8	-0.0
Leg predicted mass (left)	1.9	9.9	15.3	-3.9	-3.6	-3.6	-3.6	-3.1	-3.2	-3.6	-0.1	-3.4	-0.7
Gout (self-reported)	1.9	2.6	3.6	-1.7	-1.6	-1.8	-1.5	-1.9	-1.4	-1.4	1.2	-1.7	-1.8
Exposure to tobacco smoke outside home	1.9	2.6	3.9	-2.0	-1.7	-1.6	-2.0	0.8	-1.8	-1.6	-1.9	-1.5	0.7
Basal cell carcinoma (self-reported)	1.9	2.3	3.4	1.9	1.8	1.8	1.6	-1.1	1.7	1.6	0.5	1.8	0.8
Ulcerative Colitis (UC)	1.8	3.4	5.2	1.7	2.2	2.2	2.1	-2.3	1.8	2.1	1.3	1.4	-0.3
Type 2 Diabetes (T2D) (2012)	1.8	2.0	3.9	-1.3	-1.7	-1.6	-1.9	0.4	-2.0	-1.8	-1.2	-0.3	0.7
Cardiovascular Disease	1.8	5.9	16.8	2.7	2.3	2.5	2.2	-1.6	2.8	2.4	1.8	4.1	0.0
Hand grip strength (left)	1.8	4.7	19.6	-1.6	-1.1	-0.6	-1.9	0.8	-1.4	-1.2	-3.9	0.6	4.4
Medication for hormone replacement therapy	1.8	2.1	5.7	1.4	1.6	1.6	1.2	0.2	1.7	1.6	0.6	2.4	0.7
Heart attack	1.8	2.3	5.7	-0.8	-1.1	-1.2	-0.4	-2.4	-0.6	-0.9	2.4	-1.4	-2.3
Diabetes diagnosed by doctor	1.8	2.9	5.2	2.0	1.3	1.4	2.2	-1.5	1.0	1.7	2.1	0.5	-2.3
Medication: Aspirin	1.8	2.4	5.5	1.8	1.2	1.2	1.8	-0.3	1.5	1.4	2.3	1.4	-1.6
Medication: Atorvastatin	1.8	2.2	9.7	-0.3	-0.9	-1.0	-0.1	-2.1	-0.8	-0.6	2.0	-1.2	-3.1
Heart attack/myocardial infarction (self-reported)	1.8	2.3	4.5	-1.1	-1.5	-1.5	-0.8	-2.1	-0.9	-1.2	2.0	-1.4	-2.0
Arm predicted mass (left)	1.8	8.9	15.7	-4.0	-3.5	-3.4	-3.6	-2.9	-3.3	-3.5	-0.9	-2.0	-0.1
Number of treatments/medications taken	1.7	3.1	7.0	1.8	1.5	1.6	1.7	-1.0	1.8	1.8	2.2	2.6	-1.0
Diabetes (father)	1.7	2.1	5.8	1.4	1.5	1.3	1.4	2.4	1.8	1.4	0.9	1.3	-0.4
Forced vital capacity (FVC)	1.7	6.6	10.2	-3.2	-3.0	-3.1	-2.8	0.9	-3.1	-3.1	-0.8	-2.3	-1.8
Diabetes (self-reported)	1.7	2.7	4.5	2.1	1.5	1.7	2.1	-1.1	1.2	1.9	1.5	1.1	-1.8
Falls in the last year	1.7	2.2	3.4	1.6	1.7	1.9	1.4	-1.3	1.5	1.7	-0.8	1.4	1.5
Medication: Amlodipine	1.7	2.3	8.4	0.9	1.3	1.6	0.9	-1.5	1.5	1.5	0.5	2.9	1.4
Forced vital capacity (FVC), Best measure	1.7	6.1	9.6	-3.1	-2.8	-2.9	-2.8	1.4	-3.0	-2.9	-1.4	-2.1	-1.0
Shortness of breath walking on level ground	1.7	2.0	5.0	1.0	1.1	1.1	1.2	-2.2	1.3	1.4	1.6	1.0	-1.8
Emphysema/chronic bronchitis	1.7	2.0	3.5	1.5	1.6	1.7	1.6	-0.5	1.6	1.9	1.2	1.1	0.4
Long-standing illness, disability or infirmity	1.7	2.6	11.0	0.5	0.4	0.2	0.9	-3.3	0.4	0.8	2.4	-0.6	-2.7
Supplements: Fish oil (including cod liver oil)	1.7	2.2	3.6	1.4	1.9	1.8	1.4	-1.5	1.7	1.6	1.1	1.2	-0.3
Basal metabolic rate	1.7	9.5	15.9	-4.0	-3.5	-3.6	-3.6	-3.1	-3.3	-3.5	-0.3	-2.9	-0.6
Arm fat-free mass (left)	1.7	8.5	15.2	-3.9	-3.4	-3.3	-3.5	-2.9	-3.2	-3.4	-0.7	-2.0	-0.3
Verbal and Numeric Reasoning (VNR)	1.6	3.9	6.8	-2.1	-2.2	-2.3	-2.6	0.5	-1.9	-2.6	-1.8	-1.9	0.7
Medication: Simvastatin	1.6	2.3	4.5	1.5	1.1	1.2	1.6	-1.9	1.2	1.3	2.1	1.7	-1.3
Medication: Ventolin 100micrograms inhaler	1.6	2.1	8.6	1.0	0.7	0.4	1.1	-1.6	1.1	1.0	2.9	0.6	-2.1
Arm predicted mass (right)	1.6	8.1	14.6	-3.8	-3.3	-3.2	-3.4	-3.1	-3.1	-3.2	-0.6	-2.2	0.2
Illness, injury, bereavement, stress in last 2 years	1.6	2.0	13.2	1.2	0.7	0.8	0.8	3.6	0.6	0.7	-0.6	1.4	-0.4
Supplements: Vitamin C	1.6	1.9	4.1	1.6	1.8	1.6	1.5	0.0	2.0	1.5	1.2	0.9	0.7
Systolic blood pressure, automated reading	1.5	4.5	10.2	-2.3	-2.5	-2.1	-3.2	1.1	-2.2	-2.5	-2.5	0.3	0.2
Impedance of arm (right)	1.5	7.0	22.7	2.7	1.6	0.9	2.9	0.7	1.8	1.6	4.7	-0.9	-4.8
Breastfed as a baby	1.5	1.8	6.6	-1.0	-0.9	-0.8	-1.2	2.1	-0.8	-1.1	-2.6	-0.2	1.2
Arm fat-free mass (right)	1.5	7.7	13.8	-3.7	-3.1	-3.0	-3.2	-3.1	-3.0	-3.1	-0.7	-2.2	0.2
Had major operations	1.5	1.7	7.6	0.9	0.3	0.0	1.1	-1.8	0.2	0.3	2.8	-0.4	-2.0
Average weekly red wine intake	1.5	2.2	5.5	1.9	1.2	1.4	1.0	1.5	1.8	1.4	0.6	2.3	0.7
Allergy or Eczema	1.4	3.7	10.8	2.3	1.0	0.8	2.0	1.5	1.4	1.0	3.3	0.9	-3.1
Diabetes (mother)	1.4	1.7	8.3	0.2	-0.4	0.1	-0.7	2.9	-0.1	-0.3	-2.0	1.5	1.4
Hypothyroidism/myxoedema (self-reported)	1.4	2.6	5.8	1.1	1.4	1.4	1.9	-2.0	1.3	1.6	2.4	0.0	-2.0
Financial situation satisfaction	1.4	1.7	3.3	-1.6	-1.1	-1.1	-1.2	-0.2	-1.5	-1.1	-1.4	-1.4	1.8
Medication: Paracetamol	1.4	2.2	4.3	1.8	1.4	1.8	1.1	1.2	1.6	1.7	-0.4	2.1	1.3
Crohns Disease (2012)	1.3	2.1	5.1	-1.2	-1.2	-1.4	-0.8	-0.9	-1.5	-1.4	1.1	-2.1	-2.2
Heel T-Score	1.3	10.4	40.4	0.3	-0.4	-1.3	1.6	-4.4	-0.8	-0.8	6.4	-3.1	-5.3
Lung FVC	1.3	6.5	10.8	-3.1	-2.3	-2.1	-3.1	3.1	-2.8	-2.4	-3.3	-1.1	1.0
Impedance of leg (right)	1.3	6.1	12.7	2.6	2.3	1.9	3.4	-0.3	2.1	2.3	3.6	1.6	-2.7
Forced expiratory volume in 1-second (FEV1)	1.3	4.3	6.8	-2.5	-2.4	-2.5	-2.3	0.7	-2.6	-2.5	-0.9	-2.1	-1.2
Impedance of arm (left)	1.3	6.0	18.2	2.5	1.6	0.9	2.8	0.3	1.6	1.6	4.3	-1.5	-4.1
Hair/balding pattern: Pattern 4	1.3	3.2	6.2	2.0	1.9	1.3	2.5	-2.2	1.6	1.9	1.7	-1.4	-1.1
Alcohol intake frequency.	1.3	2.9	5.2	-2.3	-1.8	-1.9	-1.9	-0.8	-1.9	-1.7	-0.3	-2.2	-1.0
Suffer from ‘nerves’	1.3	2.0	3.6	1.9	1.8	1.6	1.7	-0.2	1.6	1.6	0.8	1.0	0.8
Medication: Gliclazide	1.3	1.5	3.2	1.8	0.9	1.1	1.4	0.5	1.1	1.3	1.4	0.8	-1.4
Hearing aid user	1.3	1.5	5.0	0.9	0.6	0.4	1.4	0.7	0.6	0.8	2.2	-0.1	-2.2
Medication: Bendroflumethiazide	1.3	2.0	6.6	1.2	1.4	1.5	1.0	-1.4	1.3	1.3	0.3	2.6	1.2
Number of operations (self-reported)	1.3	1.9	4.5	1.4	0.8	0.6	1.3	-2.1	0.8	0.8	2.1	0.7	-2.0
Fractured/broken bones in last 5 years	1.3	1.6	3.7	1.9	1.3	1.5	1.8	0.6	1.2	1.5	0.6	1.2	-0.2
Heart disease (siblings)	1.3	1.6	2.6	-1.2	-1.6	-1.3	-1.6	0.4	-1.4	-1.5	-0.9	0.3	-1.5
Impedance of whole body	1.3	6.5	18.2	2.7	2.1	1.4	3.3	0.0	2.1	2.0	4.3	-0.2	-3.7
Blood Platelet Count	1.2	13.9	29.7	3.6	4.1	4.5	2.6	2.7	4.3	3.9	-0.7	5.5	3.3
Blood White Count	1.2	8.6	22.0	2.9	2.6	2.2	3.0	-0.8	2.7	2.6	4.7	0.9	-4.4
Other serious medical condition/disability diagnosed by doctor	1.2	1.6	11.4	-0.6	-0.2	-0.3	-0.0	-3.4	-0.5	-0.1	0.4	-1.7	-0.9
Sitting height	1.2	8.2	13.0	-3.3	-3.5	-3.6	-3.3	-2.2	-3.1	-3.3	-0.4	-2.7	-1.5
Fluid intelligence score	1.2	2.4	3.9	-1.3	-1.7	-1.7	-1.8	0.9	-1.6	-1.8	-1.6	-2.0	0.6
Medication for cholesterol, blood pressure or diabetes	1.2	1.9	5.8	-0.9	-0.2	-0.5	-0.8	2.4	-0.8	-0.7	-2.2	-2.0	1.5
Leg fat percentage (right)	1.2	4.2	12.4	1.2	1.8	1.7	2.0	-3.5	1.9	1.6	3.0	1.4	-1.0
Mean time to correctly identify matches	1.2	2.3	11.4	-1.2	-0.5	-0.7	-0.6	-3.4	-0.7	-0.4	1.7	-1.9	-1.4
Medication: Aspirin	1.2	1.6	4.5	1.4	0.9	1.0	1.5	-0.2	1.1	1.0	2.1	1.1	-1.5
Medication for cholesterol	1.2	1.8	4.0	-1.4	-1.3	-1.3	-1.4	-0.2	-1.3	-1.4	-1.3	-2.0	1.2
Guilty feelings	1.2	1.8	5.2	1.4	0.9	0.6	1.6	-1.2	0.9	0.8	2.3	-0.3	-1.9
Waist Hip Ratio (WHR)	1.1	5.1	8.8	2.9	2.4	2.6	3.0	-0.3	2.1	2.7	1.9	2.2	-0.8
Lung FEV1/FVC ratio	1.1	5.7	11.0	3.3	3.0	3.3	3.1	-0.7	2.4	2.9	0.8	0.9	-0.0
Eye problems/disorders: Diabetes related eye disease	1.1	1.2	3.2	1.3	1.3	1.4	1.8	0.3	0.9	1.4	0.4	0.5	0.4
Medication: Atenolol	1.1	1.3	7.6	0.2	-0.0	-0.2	0.4	-0.2	0.1	0.0	2.0	1.2	-2.8
Impedance of leg (left)	1.1	5.2	10.7	2.6	2.3	1.9	3.3	0.3	2.1	2.2	3.1	1.4	-2.3
Medication: Cholesterol lowering	1.1	1.7	6.9	0.5	-0.1	-0.0	0.6	-2.6	0.3	0.3	2.3	0.6	-2.0
Forced expiratory volume in 1-second (FEV1), Best measure	1.1	3.6	5.6	-2.2	-2.0	-2.1	-2.0	1.4	-2.4	-2.2	-1.2	-1.9	-1.3
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.7	3.1	1.5	1.6	1.8	1.7	0.3	1.5	1.5	0.8	1.0	-0.1
Medication: Paracetamol	1.1	1.8	3.3	1.6	1.2	1.6	1.1	0.9	1.2	1.5	-0.7	1.8	1.2
Medication for pain relief, constipation, heartburn	1.1	1.9	3.2	-1.5	-1.5	-1.8	-1.6	0.3	-1.6	-1.7	-0.5	-1.7	-0.2
Smoking status: Previous	1.1	1.7	7.5	0.7	0.6	0.7	0.9	-1.1	0.4	0.8	1.4	1.9	-2.7
Handedness (chirality/laterality): Left-handed	1.1	1.4	5.5	0.1	-0.2	-0.4	0.1	-2.2	0.2	-0.0	2.3	-0.6	-1.7
Illnesses of father: None of the above (group 1)	1.1	1.3	4.3	-0.8	-0.7	-0.8	-0.9	0.7	-0.9	-1.0	-2.1	-2.0	0.4
Ever taken oral contraceptive pill	1.1	1.2	2.6	-0.8	-1.2	-1.3	-1.4	-1.6	-1.1	-1.3	-0.1	-1.0	0.4
High cholesterol (Self-reported)	1.1	1.9	5.7	1.4	0.8	0.7	1.3	-1.6	0.9	0.9	2.4	0.7	-2.0
HbA1C	1.0	1.1	2.8	-1.5	-1.2	-1.1	-1.3	0.6	-0.8	-0.5	-0.7	-1.7	0.0
Trunk fat percentage	1.0	4.2	16.4	0.9	1.3	0.8	1.6	-3.3	1.5	1.1	4.0	-0.4	-2.2
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.2	6.8	-0.3	-1.0	-1.3	0.1	-2.0	-1.0	-0.8	2.6	-1.3	-2.2
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.1	2.3	-1.5	-1.2	-1.3	-1.3	-1.1	-1.0	-1.1	-0.2	-0.8	0.2
Body fat percentage	1.0	4.1	14.4	1.0	1.4	1.0	1.7	-3.4	1.7	1.2	3.8	0.0	-1.9
Health satisfaction	1.0	1.3	5.0	-0.8	-0.6	-0.3	-0.7	-2.2	-0.5	-0.5	-1.0	-0.5	2.2
Commuting to job workplace: Public transport	1.0	1.2	3.1	-1.1	-1.3	-1.1	-1.1	-0.2	-1.1	-1.1	-0.1	-0.8	-1.7
Eye problems/disorders: Glaucoma	1.0	1.2	2.3	-1.2	-1.5	-1.3	-1.5	-1.0	-0.8	-1.4	-0.5	-0.4	-0.1
Average weekly beer plus cider intake	1.0	1.4	2.6	-1.3	-1.2	-1.2	-1.0	-0.8	-1.6	-1.2	-1.2	-1.2	0.9
Reaction Time	0.9	1.7	6.9	-1.3	-0.7	-0.9	-0.8	-2.6	-0.7	-0.6	1.4	-2.0	-0.5
Type 2 Diabetes (T2D) (2018)	0.9	1.7	3.6	1.7	1.0	1.2	1.9	-1.0	1.0	1.3	1.9	0.3	-1.1
Diverticular disease/diverticulitis (self-reported)	0.9	1.1	2.0	1.4	1.2	1.2	1.1	0.9	1.1	1.3	0.3	0.5	0.7
Medication: Levothyroxine sodium	0.9	1.5	4.5	0.1	0.4	0.3	1.1	-2.1	0.2	0.6	2.1	-1.1	-1.7
Past tobacco smoking	0.9	1.6	5.9	-0.7	-0.8	-0.9	-0.9	1.3	-0.5	-1.0	-0.9	-1.9	2.4
Had other major operations	0.9	1.1	1.8	1.3	1.0	1.0	1.3	-1.0	0.9	1.1	1.3	0.8	-0.3
Pain all over the body in last month	0.9	1.0	1.8	1.3	1.1	1.1	1.2	-0.2	1.3	1.1	0.7	0.7	-0.5
Prospective memory result	0.9	1.1	2.1	0.9	1.0	1.1	1.2	-1.0	1.2	0.9	1.4	1.1	-0.3
Exposure to tobacco smoke at home	0.9	1.0	4.1	-1.0	-0.1	-0.1	-0.8	0.1	-0.5	-0.3	-1.9	0.0	2.0
Mouth/teeth dental problems: Loose teeth	0.9	1.0	2.0	-1.2	-1.1	-0.9	-1.4	1.4	-1.1	-0.9	-1.1	0.1	-0.1
Pulse rate, automated reading	0.9	2.9	18.0	-0.0	-0.3	0.2	-0.1	1.1	-0.5	-0.2	-2.9	-0.9	4.2
Age at last live birth	0.9	1.3	4.1	-1.0	-0.6	-0.8	-0.4	-1.7	-1.1	-0.6	-1.2	-2.0	-0.7
Family relationship satisfaction	0.9	1.1	4.0	-0.7	-1.2	-1.2	-0.6	-0.8	-1.2	-1.1	-0.4	-2.0	-0.4
Knee pain experienced in last month	0.9	1.3	2.8	1.2	1.3	1.5	1.1	0.3	1.2	1.3	-0.2	1.7	1.0
Leg fat percentage (left)	0.9	3.4	10.0	1.1	1.8	1.5	1.8	-3.2	1.8	1.5	2.7	1.2	-0.6
Schizophrenia vs Biploar Disorder	0.8	1.1	2.1	1.5	1.2	1.1	1.4	0.7	0.8	1.2	0.5	1.1	0.1
Triglycerides	0.8	1.2	2.5	-1.1	-0.8	-1.0	-0.7	-1.4	-1.4	-0.9	-0.8	-1.6	-1.1
Age when periods started (menarche)	0.8	1.9	5.1	-1.3	-1.2	-1.3	-1.5	2.3	-1.3	-1.4	-0.7	-0.6	-1.3
Tinnitus: Yes, but not now, but have in the past	0.8	0.9	1.6	0.7	1.2	1.3	1.3	0.8	1.1	1.1	0.3	0.3	0.8
Nervous feelings	0.8	1.5	2.8	1.7	1.5	1.3	1.5	1.0	1.5	1.4	0.3	-0.1	-0.6
Pulse rate	0.8	1.3	8.1	0.0	-0.4	-0.0	-0.0	-0.5	-0.3	-0.3	-1.8	-1.1	2.8
Length of working week for main job	0.8	0.9	2.2	0.8	1.0	0.8	1.0	0.3	0.9	0.9	1.0	1.5	-0.7
Comparative height size at age 10	0.8	4.5	14.1	-1.1	-1.2	-1.6	-0.4	-2.7	-0.8	-1.1	3.3	-2.3	-3.8
Ever had bowel cancer screening	0.8	1.0	1.4	1.2	0.9	0.8	1.1	0.6	1.2	0.9	1.2	0.8	-1.0
Commuting to job workplace: Walk	0.8	0.9	4.0	-0.2	-0.5	-0.3	-1.1	2.0	-0.1	-0.7	-1.3	0.8	0.2
Mouth/teeth dental problems: Mouth ulcers	0.8	1.3	2.6	1.6	1.0	1.0	1.1	1.1	1.5	1.0	0.8	1.2	0.6
Mineral and other dietary supplements	0.8	1.1	1.9	-1.1	-1.3	-1.4	-0.9	1.1	-1.2	-1.1	-0.1	-0.8	-0.6
Average weekly champagne plus white wine intake	0.8	1.1	2.2	-0.8	-1.1	-1.3	-0.8	1.5	-0.9	-1.1	0.0	-1.4	-0.6
Irritability	0.8	1.3	2.3	-1.5	-1.2	-1.3	-1.3	0.8	-1.0	-1.4	-1.0	-1.2	0.1
Cholesterol lowering medication	0.8	1.2	1.9	1.4	1.1	1.0	1.3	-0.8	0.9	1.1	1.2	1.0	-0.9
Pain experienced in last month	0.8	1.4	3.9	-1.1	-0.9	-1.2	-0.6	-1.4	-1.4	-1.0	0.7	-1.1	-2.0
Depressed Affect (Nagel 2018)	0.7	1.6	4.5	-1.3	-1.4	-1.4	-1.0	-2.1	-1.2	-1.3	0.1	-0.7	-0.9
Alzheimer’s Disease (in father)	0.7	0.8	3.5	0.4	0.7	0.6	0.7	-1.9	0.6	0.7	1.0	-0.2	-1.0
Coronary Artery Disease (CAD)	0.7	0.9	2.0	-1.3	-0.9	-0.8	-1.3	-0.1	-1.1	-0.8	-0.5	-0.1	1.4
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.6	7.1	0.7	0.0	-0.3	1.0	-1.8	-0.2	0.2	2.7	-0.5	-2.1
Trunk fat mass	0.7	3.0	13.3	-0.6	-0.2	-0.6	0.0	-3.7	0.2	-0.4	3.1	-1.3	-2.0
Weight	0.7	3.6	11.4	-2.2	-1.7	-1.8	-1.6	-3.4	-1.3	-1.7	1.4	-1.8	-1.1
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.1	2.6	1.2	1.0	0.9	1.3	-1.6	1.0	1.1	1.2	-0.2	0.3
Pulse wave reflection index	0.7	0.8	2.5	0.3	0.6	0.7	0.3	-0.5	0.8	0.7	1.1	1.6	-1.4
Pulse wave peak to peak time	0.7	0.8	2.1	-0.5	-0.7	-0.9	-0.5	1.4	-1.1	-0.7	-0.5	-1.4	-0.0
Medication: Blood pressure	0.7	1.2	5.1	0.7	-0.0	0.3	0.3	-1.9	0.7	0.4	1.3	2.3	-0.8
Heart disease (mother)	0.7	0.9	7.0	-0.1	-0.4	-0.6	-0.3	0.1	-0.4	-0.4	0.7	-0.5	-2.6
Hypertension (Self-reported)	0.7	1.8	8.7	1.0	0.7	1.0	0.4	-2.1	1.1	0.9	0.6	3.0	0.4
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.8	3.3	0.3	0.3	0.2	0.7	-1.2	0.2	0.5	1.8	0.2	-1.3
Osteoarthritis (self-reported)	0.7	0.9	1.8	1.0	1.1	1.3	0.9	-1.4	1.1	1.0	-0.1	0.7	-0.3
Mother’s age at death	0.7	0.8	5.6	-0.3	-0.5	-0.7	-0.5	-0.9	-0.5	-0.6	-0.5	-2.4	-0.5
Ever smoked	0.7	1.2	5.5	0.7	0.7	0.8	0.9	-1.4	0.3	0.9	0.8	0.9	-2.3
Diastolic blood pressure, automated reading	0.7	2.1	5.0	-1.4	-1.6	-1.2	-2.2	0.1	-1.2	-1.6	-2.1	0.4	1.0
Alcohol drinker status: Previous	0.7	0.8	3.0	-0.8	-0.7	-0.8	-0.4	-0.5	-0.8	-0.7	0.0	-1.1	-1.7
Depression (Nagel 2018)	0.6	0.8	2.0	-0.7	-1.0	-1.1	-0.7	-1.4	-0.5	-0.9	0.4	-1.4	-0.4
Schizophrenia (2018)	0.6	1.2	2.0	1.0	1.4	1.4	1.2	-0.1	1.3	1.2	0.3	0.9	1.1
Worry (Nagel 2018)	0.6	1.3	2.4	1.4	1.6	1.4	1.4	0.4	1.3	1.3	0.3	0.3	-0.4
Major Depression (MDD)	0.6	0.8	5.3	0.1	-0.0	0.1	-0.3	0.9	0.4	-0.1	-0.7	0.8	2.3
Lupus	0.6	1.0	5.2	-0.1	0.1	-0.1	0.1	-2.3	-0.1	-0.1	0.0	-2.1	-0.3
Chronotype (morning person)	0.6	1.3	2.4	1.4	1.4	1.5	1.1	0.7	1.6	1.3	0.1	1.1	0.6
Relative age of first facial hair	0.6	1.2	4.1	-0.4	-0.8	-0.5	-1.1	-0.7	-0.7	-0.9	-1.4	1.4	2.0
Medication: Co-codamol	0.6	0.7	1.6	1.0	1.1	1.2	1.3	0.2	0.9	1.1	0.2	0.4	-0.1
Qualifications: CSEs or equivalent	0.6	0.8	5.1	0.3	0.6	0.6	0.3	0.0	0.5	0.5	-0.9	0.7	2.3
Ever unenthusiastic/disinterested for a whole week	0.6	0.8	4.6	0.1	-0.2	-0.0	0.2	2.1	-0.3	-0.1	-1.1	-0.1	1.2
Medication: Ramipril	0.6	0.8	4.5	-0.8	-0.5	-0.3	-0.3	-2.1	-0.4	-0.1	0.9	-0.9	-0.6
Illnesses of siblings	0.6	0.8	2.3	0.7	1.1	0.8	1.1	0.5	0.8	0.8	0.1	-1.0	1.5
Arm fat percentage (right)	0.6	2.4	8.1	0.7	1.1	0.8	1.1	-2.4	1.4	1.0	2.8	-0.1	-1.8
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	7.0	0.2	-0.2	-0.2	-0.2	2.6	-0.1	-0.3	-0.7	-0.3	1.2
Number of full brothers	0.6	0.7	2.7	0.5	0.5	0.6	0.4	0.9	0.5	0.6	0.1	1.5	-1.6
Leg fat mass (right)	0.6	2.2	15.4	-0.8	-0.1	-0.2	-0.0	-3.9	0.1	-0.2	2.2	-0.2	-0.9
Number of full sisters	0.6	0.8	3.9	-0.5	-0.7	-0.8	-0.2	0.3	-0.6	-0.6	1.2	-0.4	-2.0
Chest pain or discomfort	0.6	0.9	1.4	1.1	1.0	1.1	1.2	-0.8	0.8	1.1	0.4	1.2	0.1
Leg pain on walking	0.6	0.8	2.7	-0.5	-0.6	-0.5	-0.7	-1.6	-0.4	-0.6	-0.5	-1.5	0.7
Arm fat percentage (left)	0.6	2.6	8.2	0.8	1.2	1.0	1.2	-2.6	1.5	1.1	2.9	-0.3	-1.6
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	1.1	0.2	0.9	1.1	0.7	-0.5	1.1	1.0	1.0	1.0	-0.5
Bipolar Disorder or Schizophrenia	0.5	1.1	2.2	0.7	1.3	1.3	1.0	0.4	1.5	1.1	0.3	0.8	1.4
HDL Cholesterol	0.5	0.9	1.6	1.3	1.0	1.0	1.3	0.7	1.1	1.0	0.8	0.7	0.1
Schizophrenia (2014)	0.5	1.1	2.0	1.1	1.4	1.4	1.1	0.4	1.3	1.3	0.5	0.8	0.8
Blood Eosinophil Count	0.5	4.1	13.8	-0.6	-2.1	-2.3	-0.6	1.9	-1.8	-2.0	2.0	-1.3	-3.7
Systolic Blood Pressure	0.5	2.4	5.9	-1.3	-1.7	-1.4	-2.4	1.3	-1.3	-1.6	-2.0	1.4	0.2
Average weekly spirits intake	0.5	0.6	1.5	0.8	0.7	0.5	0.5	0.5	1.2	0.6	0.6	1.0	-1.2
Pack years adult smoking proportion	0.5	0.7	4.1	-0.7	-0.5	-0.2	-0.8	0.6	-0.2	-0.2	-1.0	0.4	2.0
Serious illness, injury or assault to yourself	0.5	0.6	2.2	0.2	0.5	0.4	0.6	-1.5	0.6	0.5	0.3	0.1	1.5
Supplements: Glucosamine	0.5	0.6	1.7	-0.8	-0.8	-0.6	-1.2	0.3	-0.4	-0.9	-1.3	-0.4	0.4
Alcohol usually taken with meals	0.5	0.7	4.9	0.2	0.2	0.2	-0.2	2.2	0.4	0.2	0.1	1.1	1.1
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	2.7	0.6	0.6	0.8	0.1	0.7	0.7	0.5	-1.2	1.0	1.6
Financial difficulties in last 2 years	0.5	0.6	1.3	-1.1	-0.9	-0.6	-1.1	-0.3	-0.8	-0.7	-0.7	0.0	1.0
Noisy workplace	0.5	0.6	1.4	0.4	0.7	0.8	0.8	-1.2	0.7	0.8	0.9	-0.7	-0.1
Mouth/teeth dental problems: Dentures	0.5	0.8	4.8	-0.6	-0.3	0.0	-0.8	0.4	-0.6	-0.3	-2.2	0.1	1.2
Medication: Lansoprazole	0.5	0.5	1.3	0.8	0.4	0.5	0.7	-0.2	0.9	0.5	0.9	1.1	-0.8
Illnesses of mother	0.5	0.6	2.3	0.1	0.5	0.2	0.8	-1.5	0.4	0.5	1.5	-0.5	-0.7
Loud music exposure frequency	0.5	0.5	2.2	-0.4	-0.4	-0.2	0.1	1.5	-0.6	-0.3	-1.2	-0.7	0.4
Neck or shoulder pain in last month	0.5	0.7	2.8	0.4	0.2	0.4	0.0	1.3	0.6	0.2	-1.4	0.3	1.7
Whole body fat mass	0.5	2.3	11.5	-0.4	0.1	-0.2	0.2	-3.4	0.3	-0.1	2.7	-0.8	-1.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	4.6	-0.3	-0.1	0.0	-0.1	-2.1	-0.2	-0.0	0.7	-0.6	-0.3
Tinnitus: Yes, now most or all of the time	0.5	0.6	2.8	-0.0	0.0	0.1	-0.1	-1.1	-0.3	-0.2	-1.2	0.4	1.7
Medication: Lisinopril	0.5	0.6	1.6	-0.6	-1.3	-1.3	-0.7	-0.0	-0.7	-1.1	-0.1	0.0	-0.4
Age started oral contraceptive pill	0.5	0.6	1.4	-0.6	-0.8	-0.9	-0.6	-0.4	-1.2	-0.8	0.6	-0.5	-0.7
Supplements: Calcium	0.5	0.5	3.1	0.1	0.0	-0.0	0.0	-1.8	0.1	0.0	0.6	-1.4	-0.1
Pack years of smoking	0.5	0.7	4.1	-0.5	-0.4	-0.1	-0.7	0.7	-0.1	-0.1	-0.9	0.7	2.0
Crohns Disease (2017)	0.4	0.9	2.8	-0.5	-0.8	-0.8	-0.4	-0.9	-0.9	-0.9	0.5	-1.7	-1.3
Irritable Bowel Disease (IBD)	0.4	1.0	2.1	0.9	1.0	1.0	1.2	-1.4	0.8	0.9	1.2	0.0	-0.9
Ovarian Cancer	0.4	0.5	0.9	-1.0	-0.7	-0.8	-0.8	0.7	-0.8	-0.7	-0.4	0.3	-0.8
Age at First Birth	0.4	0.6	1.9	-0.4	-0.7	-0.6	-0.8	0.7	-0.7	-0.8	-1.4	-0.4	0.7
Body Mass Index (BMI) (2010)	0.4	0.5	1.4	0.8	0.8	0.7	0.6	-0.0	1.2	0.8	0.8	0.1	0.2
Ulcerative Colitis	0.4	0.7	3.1	0.4	0.6	0.6	0.7	-1.8	0.3	0.7	1.0	-0.1	-0.7
Hair Pigment	0.4	12.4	25.3	-4.2	-3.6	-3.0	-4.5	0.5	-3.3	-3.6	-5.0	-2.1	3.3
Severe depression (siblings)	0.4	0.4	0.9	1.0	0.4	0.5	0.9	1.0	0.4	0.3	0.9	0.5	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.6	2.3	-0.1	-0.5	-0.6	0.1	-0.8	-0.2	-0.3	1.1	-1.5	-0.7
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	1.9	0.8	0.3	0.5	0.4	0.9	0.5	0.3	-0.5	1.4	0.6
High blood pressure	0.4	1.1	7.6	0.5	0.1	0.4	-0.1	-1.7	0.5	0.2	0.1	2.8	0.2
Waist circumference	0.4	1.4	5.5	0.2	0.6	0.5	0.6	-2.2	0.8	0.5	2.4	0.6	-0.9
Qualifications: None of the above	0.4	0.8	4.5	-0.2	0.0	0.1	0.4	-2.1	-0.2	0.2	0.8	0.5	-1.5
Hip circumference	0.4	1.6	5.4	-0.9	-0.5	-0.8	-0.4	-2.3	-0.3	-0.7	2.2	-0.9	-1.5
Father’s age at death	0.4	0.5	1.6	-0.2	-0.4	-0.3	-0.3	1.2	-0.5	-0.6	-1.3	-1.0	0.6
Qualifications: A levels/AS levels or equivalent	0.4	0.8	2.2	1.1	1.0	1.1	0.8	1.5	0.8	0.9	0.1	0.7	0.3
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	2.0	-0.2	0.2	0.3	0.0	-1.0	-0.2	0.3	-1.1	-0.1	1.4
Pulse wave Arterial Stiffness index	0.4	0.5	2.8	0.1	0.3	0.5	0.2	-1.7	0.7	0.3	0.6	1.0	-0.2
Tense / ‘highly strung’	0.4	0.7	1.2	1.1	1.1	1.1	1.0	-0.1	0.9	1.1	-0.0	-0.2	0.2
Ever highly irritable/argumentative for 2 days	0.4	0.4	1.1	-0.7	-0.6	-0.6	-0.4	-1.0	-0.7	-0.6	0.1	-1.0	-0.2
Headache pain in last month	0.4	0.7	5.0	0.4	0.2	0.4	0.2	2.2	0.4	0.2	-0.0	0.6	0.8
Chronic bronchitis/emphysema (mother)	0.4	0.4	1.1	-1.1	-0.6	-0.8	-0.9	-0.3	-0.5	-0.8	-0.4	-0.5	-0.3
Worry too long after embarrassment	0.4	0.7	1.1	1.1	0.9	0.6	1.0	-0.8	0.9	0.9	0.6	-0.8	-0.7
Qualifications: College or University degree	0.4	1.4	4.7	-0.1	-0.2	-0.4	0.4	-1.5	-0.4	-0.2	2.0	-1.5	-2.2
Angina (self-reported)	0.4	0.6	1.0	-0.7	-1.0	-0.8	-0.8	-1.0	-0.5	-0.7	0.5	0.2	-0.9
Medication: Omeprazole	0.4	0.4	1.5	0.2	0.5	0.7	0.5	0.4	0.7	0.7	0.6	1.2	-0.2
Friendships satisfaction	0.4	0.5	1.0	-0.9	-0.7	-0.7	-1.0	-0.1	-0.5	-0.8	-0.1	-0.9	-0.8
Back pain experienced in last month	0.4	0.6	3.2	0.6	0.5	0.6	0.1	-0.1	1.1	0.6	-0.1	0.7	1.8
Osteoporosis (self-reported)	0.4	0.5	2.2	-0.6	-0.5	-0.3	-0.5	0.7	-0.7	-0.4	-1.5	-0.7	0.3
Arm fat mass (left)	0.4	1.6	8.7	-0.6	-0.1	-0.3	-0.2	-3.0	0.1	-0.2	2.1	-0.7	-1.5
Vascular/heart problems diagnosed by doctor	0.4	1.2	5.6	-0.4	0.1	-0.1	0.1	2.4	-0.4	0.0	-0.8	-2.1	0.6
Leg fat mass (left)	0.4	1.8	11.8	-0.8	-0.2	-0.4	-0.2	-3.4	0.0	-0.4	2.0	-0.3	-0.7
Intelligence (Savage-Jansen 2018)	0.3	1.0	2.0	-1.2	-0.9	-1.3	-1.3	-0.4	-0.8	-1.3	-0.1	-1.4	-0.1
Sensitivity / hurt feelings	0.3	0.6	1.3	1.1	0.7	0.8	0.7	1.1	0.6	0.7	-0.5	0.6	0.5
Hearing difficulty/problems: Yes	0.3	0.4	1.2	-0.4	-0.2	-0.0	-0.8	0.3	-0.4	-0.4	-1.1	-0.4	1.1
Angina	0.3	0.5	1.0	-0.5	-0.9	-0.7	-0.7	-1.0	-0.4	-0.6	0.5	0.1	-0.8
Fed-up feelings	0.3	0.6	3.3	-0.6	-0.7	-0.7	-0.7	-1.8	-0.4	-0.7	-0.2	-0.1	0.2
High blood pressure (mother)	0.3	0.5	2.7	0.7	0.3	0.6	0.2	0.6	0.6	0.4	-0.2	1.6	0.3
Number of incorrect matches in round	0.3	0.6	0.8	0.8	0.9	0.7	0.9	0.8	0.4	0.9	0.4	-0.2	-0.9
Hearing difficulty/problems with background noise	0.3	0.5	1.9	0.4	0.8	0.9	0.1	-0.3	0.8	0.7	-0.5	0.6	1.4
Alcohol intake versus 10 years previously	0.3	0.5	1.5	0.7	0.6	0.6	0.7	-1.2	0.4	0.8	0.5	-0.3	0.6
Hair/balding pattern: Pattern 3	0.3	0.4	1.3	0.4	0.3	0.1	0.4	-0.8	0.5	0.3	0.5	-1.0	-1.1
Number of live births	0.3	0.5	1.1	0.4	0.9	0.7	0.9	-0.5	0.5	0.7	1.1	0.3	-0.3
Arm fat mass (right)	0.3	1.4	8.4	-0.5	0.1	-0.1	-0.1	-2.9	0.3	-0.1	1.9	-0.4	-1.2
Birth weight of first child	0.3	0.6	1.4	0.9	0.5	0.5	0.7	0.2	1.1	0.5	0.1	-0.9	1.2
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	1.6	-0.4	-0.4	-0.4	-0.0	-1.2	-0.4	-0.4	0.7	-1.3	-0.2
High blood pressure (siblings)	0.3	0.5	2.8	0.2	0.3	0.6	-0.2	-0.6	0.4	0.5	-0.4	1.7	0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.9	-0.2	0.0	-0.1	0.1	-0.6	0.1	-0.1	1.1	0.2	-1.4
Overall health rating	0.3	0.6	4.8	-0.3	-0.5	-0.4	-0.4	-2.2	-0.0	-0.1	0.6	-0.2	-0.8
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	1.5	-0.5	-0.3	-0.3	-0.7	0.8	-0.6	-0.5	-1.2	-0.5	-0.3
Commuting to job workplace: Car/motor vehicle	0.3	0.4	0.9	0.6	0.6	0.4	0.8	-0.9	0.4	0.6	0.6	-0.6	0.4
Illnesses of father: Heart disease	0.3	0.5	1.1	-0.8	-0.6	-0.3	-1.0	-0.5	-0.6	-0.5	-1.0	0.3	0.5
Mood swings	0.3	0.5	1.0	-1.0	-0.9	-0.9	-0.5	-0.3	-0.8	-0.8	0.1	-0.4	-0.8
Qualifications: nursing, teaching	0.3	0.5	2.5	0.3	0.7	0.7	0.3	0.2	0.9	0.6	0.5	0.2	1.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	4.3	0.1	0.0	-0.1	-0.1	2.1	-0.2	-0.3	0.0	0.0	-1.1
Wears glasses or contact lenses	0.3	0.4	1.0	-0.3	-0.4	-0.4	-1.0	0.3	-0.0	-0.7	-0.8	0.3	0.8
Pain type(s) experienced in last month: Hip pain	0.3	0.4	2.4	-0.1	-0.1	0.0	-0.2	-1.6	-0.1	0.1	-0.4	-0.9	0.4
Illnesses of father: High blood pressure	0.3	0.3	0.6	-0.7	-0.7	-0.6	-0.7	-0.4	-0.5	-0.5	0.2	0.6	0.8
Unable to work because of sickness or disability	0.3	0.4	1.5	-0.5	-0.4	-0.5	-0.1	-1.2	-0.4	-0.3	0.1	-1.2	-0.2
Myopia	0.3	0.4	0.7	0.7	0.7	0.7	0.8	0.4	0.5	0.8	0.8	0.0	-0.4
Neuroticism (Nagel 2018)	0.2	0.4	1.0	0.5	0.5	0.3	0.8	-1.0	0.4	0.4	0.5	0.0	-1.0
Alzheimer’s Disease (in mother)	0.2	0.3	2.2	-0.0	0.0	0.1	-0.2	0.4	0.2	-0.0	-0.5	0.2	1.5
Bipolar Disorder (2011)	0.2	0.2	1.0	-0.3	-0.1	-0.0	-0.2	-1.0	0.0	0.0	-0.1	-0.3	0.9
Fasting Glucose	0.2	0.2	1.0	-0.5	-0.5	-0.3	-0.3	0.2	-1.0	-0.5	-0.5	-0.2	0.3
Rheumatoid Arthritis	0.2	0.3	1.5	-0.2	-0.1	0.2	-0.5	0.9	0.3	-0.1	-0.2	1.2	-0.3
BMI	0.2	1.4	10.8	0.0	0.4	0.3	0.2	-3.3	0.5	0.3	1.7	0.3	-0.0
Smoking Status	0.2	0.5	2.0	-0.0	-0.1	0.1	0.1	-1.4	-0.3	0.3	0.9	0.2	-1.3
Neuroticism	0.2	0.5	1.8	0.6	0.3	0.1	0.6	-1.1	0.3	0.1	0.9	-0.1	-1.3
Frequency of depressed mood in last 2 weeks	0.2	0.3	0.5	-0.4	-0.5	-0.6	-0.5	-0.7	-0.2	-0.5	0.5	-0.4	-0.6
Townsend deprivation index at recruitment	0.2	0.3	1.2	-0.5	-0.2	-0.4	-0.0	-0.6	-0.2	-0.2	1.1	-0.7	-0.3
Stomach or abdominal pain in last month	0.2	0.2	0.7	-0.1	0.2	0.2	0.3	-0.7	-0.1	0.2	0.1	-0.8	0.7
Body mass index (BMI)	0.2	0.8	5.6	-0.2	0.4	0.5	-0.0	-2.4	0.7	0.3	0.8	0.6	0.7
Had menopause	0.2	0.2	0.6	0.3	0.1	0.3	0.2	-0.4	0.1	0.2	0.5	0.8	-0.8
Mouth/teeth dental problems	0.2	0.3	0.6	-0.4	-0.5	-0.7	-0.2	-0.3	-0.5	-0.6	0.4	-0.8	-0.6
Neuroticism score	0.2	0.3	1.3	0.4	0.3	0.1	0.4	-1.1	0.4	0.2	0.8	-0.6	-0.6
Worrier / anxious feelings	0.2	0.3	0.6	0.6	0.7	0.6	0.8	-0.1	0.8	0.6	0.6	0.2	-0.6
Comparative body size at age 10	0.2	0.5	2.9	0.2	-0.2	-0.1	0.1	-1.4	0.1	-0.1	1.7	-0.5	-0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	0.4	0.6	0.5	0.5	0.6	0.5	0.4	0.2	0.5	0.2	0.1
Age at first live birth	0.2	0.4	2.0	-0.3	-0.1	-0.1	-0.1	-0.9	-0.5	-0.3	-1.4	-1.0	0.4
Eye problems/disorders: None of the above	0.2	0.2	0.7	-0.7	-0.2	-0.1	-0.1	-0.4	-0.8	-0.1	0.3	-0.5	-0.4
Migraine (self-reported)	0.2	0.3	2.4	0.3	0.3	0.3	0.4	1.6	0.3	0.2	0.3	-0.0	-0.1
Medication: Ibuprofen	0.2	0.2	0.8	0.2	0.4	0.5	0.5	-0.9	-0.0	0.5	-0.3	0.4	0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.3	1.3	0.1	0.2	0.0	0.4	-1.2	-0.1	0.1	0.5	-0.9	-0.3
Eye problems/disorders: Cataract	0.2	0.2	0.6	0.4	-0.1	0.1	-0.2	0.8	0.3	-0.0	-0.7	0.7	-0.2
Medication: Blood pressure	0.2	0.3	1.6	0.6	0.4	0.4	0.6	-0.2	0.4	0.4	0.6	1.3	-0.3
Risk taking	0.2	0.2	0.7	-0.3	-0.5	-0.3	-0.2	0.2	-0.9	-0.2	-0.7	-0.3	-0.7
Ever depressed for a whole week	0.2	0.2	0.9	-0.2	-0.5	-0.4	-0.2	0.4	-0.5	-0.3	0.0	-0.9	-0.6
Commuting to job workplace: Cycle	0.2	0.3	0.7	0.6	0.5	0.8	0.3	-0.1	0.5	0.8	-0.5	0.5	0.3
Bipolar Disorder (2018)	0.1	0.1	0.6	-0.1	0.4	0.4	0.1	0.4	0.8	0.2	0.0	0.1	0.3
Alzheimer’s Disease (including proxy)	0.1	0.2	1.1	-0.1	0.2	0.2	-0.1	-1.1	0.3	0.1	-0.0	-0.3	0.5
Neuroticism (2016)	0.1	0.1	0.8	0.5	0.2	0.3	0.4	0.9	0.1	0.1	0.2	0.1	0.4
Blood Red Count	0.1	1.0	5.3	-0.2	-0.4	-0.7	-0.2	1.3	-0.7	-0.4	1.3	-0.1	-2.3
Current tobacco smoking	0.1	0.1	0.2	-0.3	-0.1	-0.0	-0.2	-0.5	-0.3	0.1	-0.1	-0.5	0.3
Relative age voice broke	0.1	0.2	0.9	-0.1	-0.1	0.1	-0.3	-0.4	-0.1	-0.1	-0.7	0.1	0.9
Depression (self-reported)	0.1	0.1	0.6	-0.1	0.1	0.1	0.1	0.2	-0.1	0.1	-0.3	0.7	-0.8
Peak expiratory flow (PEF)	0.1	0.2	1.7	0.4	0.3	0.4	0.2	-0.0	0.2	0.2	-0.0	0.2	1.3
Medication: Seretide 50 evohaler	0.1	0.2	0.7	-0.0	-0.1	-0.0	0.0	-0.8	-0.2	0.1	0.3	0.3	-0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.2	1.4	-0.1	0.0	-0.0	0.0	-0.1	0.2	0.0	0.2	-0.2	1.2
Smoking status: Current	0.1	0.1	0.3	-0.3	-0.1	0.0	-0.2	-0.4	-0.2	0.1	-0.3	-0.5	0.6
Miserableness	0.1	0.2	2.0	0.3	-0.1	-0.1	-0.0	-1.4	0.0	-0.1	-0.0	-0.1	0.2
Tanning	0.0	0.5	1.3	-0.7	-0.4	-0.6	-0.6	0.6	-1.0	-0.6	-0.8	-0.5	-1.2
Time employed in main current job	0.0	0.1	0.4	-0.3	-0.0	0.1	-0.1	-0.1	-0.0	0.0	-0.0	-0.7	-0.1

Hub : Genes

PEX14

Models

Trait associations