[Hub]/) : Traits : Allergy :

chr6:25,266,147-26,689,223

Best TWAS P=5.51e-12 · Best GWAS P=1.45e-12 conditioned to 0.019

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous U91328.19 0.40 0.46 lasso 8 0.46 4.2e-41 -6.0 6.0 2.7e-09 -0.87 0.76 0.24 FALSE
2 GTEx Adipose Visceral Omentum U91328.19 0.21 0.25 lasso 8 0.27 3.7e-14 -6.0 6.5 1.2e-10 -0.93 0.01 0.99 FALSE
3 GTEx Adrenal Gland U91328.19 0.28 0.12 lasso 10 0.14 1.3e-05 -3.9 6.0 2.1e-09 -0.86 0.04 0.96 FALSE
4 GTEx Artery Aorta U91328.19 0.32 0.24 lasso 7 0.25 8.3e-14 -7.0 6.9 6.8e-12 -0.94 0.01 0.99 FALSE
5 GTEx Artery Tibial U91328.19 0.26 0.32 lasso 5 0.31 1.6e-24 -6.0 6.0 1.6e-09 -0.88 0.45 0.55 FALSE
6 GTEx Brain Caudate basal ganglia U91328.19 0.23 0.16 lasso 10 0.16 3.1e-05 -5.1 6.3 2.4e-10 -0.75 0.18 0.75 FALSE
7 GTEx Brain Frontal Cortex BA9 U91328.19 0.17 0.16 lasso 4 0.18 1.8e-05 -5.1 5.2 1.8e-07 -0.83 0.04 0.92 FALSE
8 GTEx Breast Mammary Tissue U91328.19 0.38 0.39 lasso 5 0.38 2.2e-20 -6.0 6.0 1.7e-09 -0.87 0.30 0.70 FALSE
9 GTEx Breast Mammary Tissue (Male) U91328.19 0.35 0.15 enet 25 0.15 2.9e-04 -6.0 5.6 2.5e-08 -0.78 0.02 0.95 FALSE
10 GTEx Breast Mammary Tissue (Female) U91328.19 0.39 0.27 lasso 6 0.23 1.4e-07 -6.0 5.9 3.8e-09 -0.85 0.04 0.96 FALSE
11 GTEx Cells Transformed fibroblasts U91328.19 0.58 0.62 lasso 8 0.60 6.2e-56 -6.0 6.0 1.5e-09 -0.87 0.72 0.28 FALSE
12 GTEx Esophagus Gastroesophageal Junction U91328.19 0.28 0.07 lasso 7 0.21 4.3e-08 -5.1 5.1 2.9e-07 -0.76 0.02 0.97 FALSE
13 GTEx Esophagus Mucosa U91328.19 0.45 0.42 lasso 7 0.44 6.3e-32 -6.0 6.1 1.3e-09 -0.90 0.12 0.88 FALSE
14 GTEx Esophagus Muscularis TRIM38 0.06 0.04 lasso 4 0.02 1.7e-02 -7.0 6.9 5.5e-12 -0.85 0.07 0.86 TRUE
15 GTEx Esophagus Muscularis U91328.19 0.36 0.30 lasso 10 0.30 1.7e-18 -7.0 6.5 1.1e-10 -0.96 0.01 0.99 FALSE
16 GTEx Heart Atrial Appendage U91328.19 0.25 0.17 enet 6 0.13 2.0e-06 -6.0 6.4 1.9e-10 -0.92 0.02 0.98 FALSE
17 GTEx Heart Left Ventricle U91328.19 0.20 0.18 lasso 5 0.15 2.4e-08 -6.0 6.0 2.4e-09 -0.86 0.09 0.91 FALSE
18 GTEx Lung U91328.19 0.20 0.22 enet 15 0.24 2.9e-18 -7.1 6.6 3.4e-11 -0.95 0.01 0.99 FALSE
19 GTEx Muscle Skeletal U91328.19 0.28 0.26 enet 15 0.32 1.3e-31 -6.0 5.6 2.1e-08 -0.80 0.52 0.48 FALSE
20 GTEx Nerve Tibial U91328.19 0.46 0.38 lasso 10 0.36 1.4e-26 -6.0 5.9 4.0e-09 -0.87 0.73 0.27 FALSE
21 GTEx Ovary U91328.19 0.37 0.17 enet 18 0.34 4.7e-09 -5.1 5.4 6.9e-08 -0.84 0.01 0.98 FALSE
22 GTEx Prostate U91328.19 0.30 0.39 lasso 2 0.37 3.0e-10 -6.0 6.0 2.1e-09 -0.87 0.04 0.96 FALSE
23 GTEx Skin Not Sun Exposed Suprapubic U91328.19 0.39 0.37 lasso 11 0.34 2.4e-19 -6.0 6.3 2.4e-10 -0.91 0.04 0.96 FALSE
24 GTEx Skin Sun Exposed Lower leg U91328.19 0.29 0.34 lasso 6 0.34 5.6e-29 -6.0 6.0 1.4e-09 -0.86 0.61 0.39 FALSE
25 GTEx Thyroid U91328.19 0.21 0.17 lasso 5 0.17 6.4e-13 -6.0 5.9 4.4e-09 -0.85 0.10 0.90 FALSE
26 GTEx Uterus U91328.19 0.38 0.05 enet 21 0.04 6.2e-02 -7.1 6.5 6.5e-11 -0.85 0.02 0.91 FALSE
27 GTEx Vagina U91328.19 0.45 0.27 lasso 4 0.26 9.4e-07 -6.0 5.9 2.8e-09 -0.85 0.03 0.96 FALSE
28 METSIM Adipose U91328.19 0.19 0.24 lasso 23 0.25 1.7e-36 -6.0 5.9 3.0e-09 -0.85 0.85 0.15 FALSE