[Hub]/) : Traits : Allergy : ← →

chr12:120,502,726-122,037,099

Best TWAS P=1.51e-09 · Best GWAS P=4.94e-10 conditioned to 0.00589

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
6	GTEx	Nerve Tibial	SPPL3	0.24	0.16	enet	33	0.21	4.8e-15	-5.7	-6.0	1.5e-09	-0.71	0.03	0.97	TRUE
10	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	SPPL3	0.11	0.01	lasso	1	0.01	1.0e-01	-6.0	-6.0	2.0e-09	-0.81	0.02	0.65	FALSE
5	GTEx	Esophagus Muscularis	SPPL3	0.16	0.14	lasso	2	0.16	3.8e-10	-5.7	-6.0	2.1e-09	-0.73	0.05	0.95	FALSE
8	GTEx	Testis	SPPL3	0.31	0.30	lasso	3	0.27	2.0e-12	-5.7	-5.9	3.9e-09	-0.77	0.03	0.97	FALSE
3	GTEx	Brain Cerebellum	SPPL3	0.29	0.22	enet	9	0.24	8.6e-08	-5.7	-5.8	6.7e-09	-0.80	0.05	0.95	FALSE
11	The Cancer Genome Atlas	Brain Lower Grade Glioma	SPPL3	0.07	0.09	lasso	3	0.09	9.9e-11	-5.7	-5.7	9.8e-09	-0.76	0.05	0.95	FALSE
7	GTEx	Pancreas	SPPL3	0.14	0.10	lasso	3	0.09	9.3e-05	-6.0	-5.7	1.5e-08	-0.76	0.04	0.89	FALSE
4	GTEx	Breast Mammary Tissue (Female)	SPPL3	0.24	0.14	enet	7	0.03	5.1e-02	-6.0	-5.7	1.6e-08	-0.77	0.04	0.87	FALSE
1	GTEx	Adipose Subcutaneous	SPPL3	0.19	0.19	lasso	8	0.19	3.7e-15	-5.7	-5.5	2.8e-08	-0.75	0.03	0.97	FALSE
12	The Cancer Genome Atlas	Prostate Adenocarcinoma	SPPL3	0.04	0.04	blup	95	0.04	3.7e-05	-6.0	-5.5	3.4e-08	-0.76	0.03	0.97	FALSE
9	METSIM	Adipose	SPPL3	0.12	0.15	lasso	8	0.16	1.6e-22	-6.0	-5.5	3.7e-08	-0.77	0.01	0.99	FALSE
2	GTEx	Artery Aorta	SPPL3	0.18	0.15	enet	13	0.17	1.4e-09	-6.0	-5.2	1.9e-07	-0.69	0.02	0.98	FALSE