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chr12:55,601,472-58,677,299

Best TWAS P=1.76e-21 · Best GWAS P=1.4e-27 conditioned to 0.0229

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
31	GTEx	Prostate	SUOX	0.22	0.04	enet	11	0.05	2.3e-02	-8.42	9.5	1.8e-21	0.04	0.04	0.74	TRUE
53	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	GPR182	0.07	0.00	lasso	2	0.00	8.8e-02	9.27	9.4	5.0e-21	0.75	0.00	0.89	TRUE
74	The Cancer Genome Atlas	Thyroid Carcinoma	STAT6	0.04	0.01	blup	47	0.01	2.3e-02	-7.17	-7.7	1.8e-14	-0.27	0.08	0.06	TRUE
61	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	RPS26	0.22	0.31	lasso	3	0.31	1.6e-35	-8.92	-9.2	5.0e-20	-0.03	0.02	0.98	FALSE
49	The Cancer Genome Atlas	Colon Adenocarcinoma	RPS26	0.43	0.48	lasso	4	0.47	1.8e-30	-8.92	-9.2	5.4e-20	-0.03	0.02	0.98	FALSE
65	The Cancer Genome Atlas	Prostate Adenocarcinoma	RPS26	0.33	0.52	enet	9	0.54	5.6e-66	-8.92	-9.2	5.9e-20	-0.03	0.02	0.98	FALSE
72	The Cancer Genome Atlas	Testicular Germ Cell Tumors	RPS26	0.46	0.64	lasso	4	0.65	8.5e-30	-8.92	-9.1	6.0e-20	-0.03	0.04	0.96	FALSE
48	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	RPS26	0.23	0.40	lasso	2	0.39	1.5e-20	-8.92	-9.1	8.2e-20	-0.03	0.02	0.98	FALSE
62	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	RPS26	0.30	0.20	lasso	4	0.24	3.9e-16	-8.92	-9.1	8.3e-20	-0.03	0.02	0.98	FALSE
60	The Cancer Genome Atlas	Lung Adenocarcinoma	RPS26	0.26	0.45	enet	9	0.47	3.6e-61	-8.92	-9.1	9.1e-20	-0.04	0.03	0.97	FALSE
50	The Cancer Genome Atlas	Esophageal Carcinoma	RPS26	0.19	0.13	lasso	5	0.11	2.4e-04	-8.92	-9.1	1.0e-19	-0.03	0.01	0.98	FALSE
71	The Cancer Genome Atlas	Stomach Adenocarcinoma	RPS26	0.19	0.32	lasso	5	0.34	2.0e-25	-8.88	-9.0	1.6e-19	-0.04	0.06	0.94	FALSE
1	CommonMind	Brain Pre-frontal Cortex	RPS26	0.48	0.62	lasso	5	0.63	5.9e-99	-8.92	-9.0	1.7e-19	-0.04	0.03	0.97	FALSE
68	The Cancer Genome Atlas	Soft Tissue Sarcoma	RPS26	0.23	0.31	lasso	3	0.30	2.4e-18	-8.92	-9.0	1.9e-19	-0.03	0.02	0.98	FALSE
55	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	RPS26	0.27	0.38	enet	8	0.40	5.0e-24	-8.92	-9.0	2.0e-19	-0.04	0.03	0.97	FALSE
46	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	RPS26	0.14	0.22	lasso	2	0.23	4.8e-19	-8.88	-8.9	3.6e-19	-0.04	0.04	0.96	FALSE
52	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	RPS26	0.17	0.29	lasso	4	0.29	6.2e-33	-8.88	-8.9	3.6e-19	-0.04	0.05	0.95	FALSE
47	The Cancer Genome Atlas	Breast Invasive Carcinoma	RPS26	0.30	0.44	enet	10	0.45	5.2e-104	-8.92	-8.9	5.1e-19	-0.03	0.02	0.98	FALSE
57	The Cancer Genome Atlas	Brain Lower Grade Glioma	RPS26	0.31	0.53	enet	8	0.55	1.7e-74	-8.92	-8.9	5.2e-19	-0.04	0.04	0.96	FALSE
58	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	RPS26	0.18	0.31	lasso	2	0.29	3.9e-14	-8.92	-8.9	5.6e-19	-0.03	0.03	0.97	FALSE
43	METSIM	Adipose	RPS26	0.30	0.40	lasso	5	0.41	7.2e-66	-8.88	-8.9	6.0e-19	-0.04	0.04	0.96	FALSE
67	The Cancer Genome Atlas	Rectum Adenocarcinoma	RPS26	0.24	0.18	lasso	2	0.20	1.9e-05	-8.92	-8.9	6.5e-19	-0.04	0.03	0.76	FALSE
76	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	RPS26	0.17	0.19	lasso	4	0.18	1.3e-05	-8.92	-8.9	7.0e-19	-0.04	0.02	0.98	FALSE
51	The Cancer Genome Atlas	Glioblastoma Multiforme	RPS26	0.41	0.38	enet	9	0.39	7.9e-13	-8.88	-8.8	1.0e-18	-0.04	0.06	0.94	FALSE
6	GTEx	Artery Tibial	RPS26	0.07	0.02	enet	5	0.01	3.5e-02	-8.92	-8.8	1.1e-18	-0.04	0.04	0.86	FALSE
15	GTEx	Esophagus Gastroesophageal Junction	SUOX	0.20	0.16	lasso	5	0.19	2.7e-07	-8.42	8.8	1.5e-18	0.04	0.06	0.94	FALSE
63	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	RPS26	0.36	0.44	lasso	7	0.42	2.4e-19	-8.88	-8.8	1.8e-18	-0.05	0.08	0.92	FALSE
64	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	RPS26	0.47	0.43	lasso	2	0.44	3.2e-19	-8.42	-8.7	2.5e-18	-0.04	0.06	0.94	FALSE
38	GTEx	Testis	SUOX	0.27	0.18	lasso	14	0.18	1.4e-08	-8.42	8.7	5.0e-18	0.04	0.08	0.92	FALSE
42	METSIM	Adipose	IKZF4	0.04	0.04	enet	3	0.04	1.0e-06	-8.51	-8.6	6.2e-18	-0.04	0.13	0.87	FALSE
34	GTEx	Skin Sun Exposed Lower leg	SUOX	0.23	0.30	lasso	3	0.29	1.9e-24	-8.42	8.6	6.4e-18	0.04	0.68	0.32	FALSE
13	GTEx	Colon Sigmoid	SUOX	0.23	0.18	lasso	4	0.15	7.9e-06	-8.42	8.6	1.0e-17	0.04	0.05	0.94	FALSE
69	The Cancer Genome Atlas	Skin Cutaneous Melanoma	RPS26	0.28	0.15	lasso	2	0.17	3.0e-05	-8.22	-8.6	1.1e-17	-0.04	0.01	0.94	FALSE
73	The Cancer Genome Atlas	Thyroid Carcinoma	RPS26	0.33	0.51	enet	19	0.50	7.3e-56	-8.92	-8.6	1.2e-17	-0.02	0.02	0.98	FALSE
20	GTEx	Heart Atrial Appendage	SUOX	0.09	0.10	enet	8	0.09	1.1e-04	-8.92	8.5	2.0e-17	0.05	0.05	0.86	FALSE
39	GTEx	Thyroid	SUOX	0.37	0.40	lasso	7	0.38	5.4e-31	-8.42	8.5	2.0e-17	0.04	0.70	0.30	FALSE
32	GTEx	Skin Not Sun Exposed Suprapubic	SUOX	0.10	0.14	lasso	2	0.12	2.5e-07	-8.42	8.5	2.4e-17	0.04	0.18	0.80	FALSE
41	GTEx	Whole Blood	RPS26	0.05	0.05	lasso	1	0.05	3.4e-05	-8.42	-8.4	3.7e-17	-0.05	0.05	0.93	FALSE
12	GTEx	Cells Transformed fibroblasts	RPS26	0.11	0.08	enet	15	0.09	3.4e-07	-8.88	-8.4	5.0e-17	-0.04	0.08	0.92	FALSE
11	GTEx	Breast Mammary Tissue (Female)	RPS26	0.20	0.11	lasso	3	0.10	6.6e-04	-8.42	-8.4	5.6e-17	-0.07	0.05	0.25	FALSE
18	GTEx	Esophagus Muscularis	SUOX	0.24	0.19	enet	16	0.15	2.3e-09	-8.42	8.3	7.4e-17	0.03	0.44	0.56	FALSE
8	GTEx	Brain Cortex	SUOX	0.16	0.11	lasso	4	0.10	1.1e-03	-8.42	8.3	8.2e-17	0.04	0.04	0.60	FALSE
24	GTEx	Muscle Skeletal	AC034102.1	0.28	0.31	lasso	4	0.31	2.3e-31	-8.13	8.3	9.2e-17	0.02	0.55	0.45	FALSE
22	GTEx	Muscle Skeletal	RAB5B	0.29	0.32	lasso	4	0.33	1.3e-33	-8.01	8.3	9.8e-17	0.02	0.71	0.29	FALSE
27	GTEx	Ovary	SUOX	0.23	0.14	enet	12	0.21	8.4e-06	-8.42	8.3	1.3e-16	0.01	0.07	0.53	FALSE
45	YFS	Blood	SUOX	0.11	0.09	bslmm	269	0.09	3.4e-27	-8.42	8.3	1.3e-16	0.03	0.70	0.30	FALSE
36	GTEx	Stomach	SUOX	0.15	0.17	enet	8	0.09	6.7e-05	-8.42	8.2	1.6e-16	0.04	0.50	0.45	FALSE
66	The Cancer Genome Atlas	Prostate Adenocarcinoma	SDR9C7	0.12	0.04	lasso	2	0.04	2.9e-05	7.80	8.1	6.1e-16	0.59	0.07	0.79	FALSE
54	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	RPS26	0.50	0.45	enet	13	0.52	1.4e-67	-8.88	-8.1	7.8e-16	-0.04	0.07	0.93	FALSE
26	GTEx	Nerve Tibial	RPS26	0.12	0.09	enet	7	0.11	3.0e-08	-7.86	-8.1	8.1e-16	-0.04	0.08	0.92	FALSE
2	GTEx	Artery Aorta	SUOX	0.36	0.30	lasso	7	0.35	3.8e-20	-8.42	8.1	8.3e-16	0.03	0.16	0.84	FALSE
7	GTEx	Brain Cerebellum	SUOX	0.24	0.20	lasso	6	0.20	1.2e-06	-8.42	7.9	3.9e-15	0.04	0.12	0.80	FALSE
25	GTEx	Nerve Tibial	SUOX	0.34	0.30	enet	22	0.35	8.5e-26	-8.42	7.8	6.1e-15	0.01	0.41	0.59	FALSE
37	GTEx	Stomach	RPS26	0.16	0.08	enet	5	0.05	1.8e-03	-8.42	-7.8	6.1e-15	-0.05	0.06	0.71	FALSE
28	GTEx	Ovary	RPS26	0.50	0.24	enet	25	0.22	5.0e-06	-8.51	-7.6	2.8e-14	-0.04	0.07	0.91	FALSE
23	GTEx	Muscle Skeletal	SUOX	0.11	0.04	lasso	7	0.04	4.4e-05	-8.42	7.6	3.7e-14	0.04	0.16	0.79	FALSE
40	GTEx	Whole Blood	SUOX	0.07	0.01	enet	20	0.02	1.1e-02	-8.92	7.4	1.0e-13	0.02	0.01	0.96	FALSE
4	GTEx	Artery Tibial	SUOX	0.18	0.14	enet	23	0.18	2.1e-14	-8.42	7.3	2.2e-13	0.01	0.20	0.80	FALSE
9	GTEx	Brain Nucleus accumbens basal ganglia	SUOX	0.18	0.08	lasso	4	0.10	1.1e-03	-8.42	7.3	3.8e-13	0.04	0.06	0.51	FALSE
10	GTEx	Breast Mammary Tissue	RPS26	0.29	0.05	enet	37	0.12	9.4e-07	-8.92	-7.2	6.4e-13	-0.08	0.05	0.95	FALSE
59	The Cancer Genome Atlas	Lung Adenocarcinoma	RAB5B	0.03	0.02	enet	7	0.02	4.3e-03	-8.01	-7.0	2.3e-12	-0.06	0.02	0.48	FALSE
3	GTEx	Artery Aorta	STAT6	0.12	0.07	enet	22	0.05	1.1e-03	-9.53	-6.9	3.8e-12	-0.30	0.51	0.04	FALSE
35	GTEx	Spleen	SUOX	0.34	0.31	enet	15	0.28	5.4e-08	-8.42	6.9	5.5e-12	0.01	0.14	0.74	FALSE
29	GTEx	Pancreas	SUOX	0.30	0.20	enet	23	0.30	3.5e-13	-8.42	6.7	1.8e-11	-0.01	0.12	0.87	FALSE
56	The Cancer Genome Atlas	Brain Lower Grade Glioma	ERBB3	0.07	0.02	blup	29	0.05	2.1e-06	-9.21	-6.7	2.3e-11	0.00	0.00	1.00	FALSE
19	GTEx	Esophagus Muscularis	RPS26	0.19	0.06	enet	46	0.05	9.3e-04	-8.92	-6.7	2.6e-11	-0.04	0.05	0.70	FALSE
5	GTEx	Artery Tibial	STAT6	0.08	0.03	enet	4	0.02	1.3e-02	-3.28	-6.5	6.4e-11	-0.07	0.29	0.06	FALSE
21	GTEx	Lung	SUOX	0.34	0.23	enet	38	0.26	4.6e-20	-8.42	6.4	2.0e-10	0.04	0.70	0.30	FALSE
75	The Cancer Genome Atlas	Thyroid Carcinoma	TMEM194A	0.15	0.07	blup	43	0.09	1.9e-09	-5.34	-6.2	7.1e-10	-0.44	0.68	0.12	FALSE
14	GTEx	Colon Transverse	SUOX	0.24	0.22	enet	24	0.25	3.8e-12	-8.42	6.0	2.2e-09	0.01	0.17	0.83	FALSE
30	GTEx	Pituitary	SUOX	0.44	0.13	enet	20	0.27	1.4e-07	-8.88	5.9	3.1e-09	0.01	0.08	0.50	FALSE
16	GTEx	Esophagus Gastroesophageal Junction	WIBG	0.16	0.02	lasso	5	0.04	1.9e-02	-0.59	5.5	4.4e-08	0.00	0.02	0.70	FALSE
17	GTEx	Esophagus Muscularis	LRP1	0.07	0.00	enet	12	0.00	3.6e-01	-3.11	5.5	4.8e-08	0.24	0.10	0.12	FALSE
44	METSIM	Adipose	SUOX	0.04	0.01	blup	288	0.02	1.1e-03	-8.51	5.4	5.4e-08	0.03	0.29	0.60	FALSE
70	The Cancer Genome Atlas	Stomach Adenocarcinoma	ERBB3	0.13	0.01	enet	12	0.03	1.9e-03	-8.88	5.3	1.3e-07	0.02	0.01	0.33	FALSE
33	GTEx	Skin Not Sun Exposed Suprapubic	KIF5A	0.13	0.00	enet	9	0.03	6.7e-03	-3.67	-5.2	2.4e-07	-0.10	0.35	0.04	FALSE