Best TWAS P=1.27e-08 · Best GWAS P=2.05e-07 conditioned to 0.0266
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | RP11-400F19.6 | 0.07 | 0.01 | lasso | 5 | 0.01 | 3.0e-02 | 5.0 | -5.2 | 2.1e-07 | -0.89 | 0.01 | 0.97 | FALSE |
| 2 | GTEx | Esophagus Muscularis | NAGLU | 0.29 | 0.09 | lasso | 5 | 0.07 | 6.2e-05 | 4.4 | -5.3 | 1.0e-07 | -0.78 | 0.11 | 0.80 | FALSE |
| 3 | GTEx | Esophagus Muscularis | RP11-400F19.8 | 0.17 | 0.05 | lasso | 4 | 0.02 | 3.9e-02 | 4.4 | -5.7 | 1.3e-08 | -0.60 | 0.04 | 0.42 | TRUE |