Best TWAS P=2.89e-10 · Best GWAS P=1.41e-10 conditioned to 0.0672
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Testis | MAP3K14-AS1 | 0.26 | 0.18 | lasso | 4 | 0.17 | 4.6e-08 | -6.1 | -5.6 | 2.7e-08 | 0.93 | 0.01 | 0.99 | FALSE |
| 2 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | LOC644172 | 0.08 | 0.00 | blup | 79 | 0.04 | 3.2e-04 | 3.9 | 5.2 | 2.4e-07 | -0.69 | 0.03 | 0.66 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | C17orf46 | 0.04 | 0.02 | enet | 5 | 0.04 | 4.1e-08 | 4.1 | -5.3 | 8.7e-08 | 0.79 | 0.01 | 0.98 | FALSE |
| 4 | The Cancer Genome Atlas | Colon Adenocarcinoma | C17orf46 | 0.07 | 0.00 | enet | 6 | 0.05 | 1.0e-03 | -6.4 | -6.0 | 1.7e-09 | 0.82 | 0.00 | 0.92 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | C17orf46 | 0.05 | 0.03 | blup | 36 | 0.03 | 4.8e-04 | 4.1 | -5.7 | 9.5e-09 | 0.84 | 0.02 | 0.93 | FALSE |
| 6 | The Cancer Genome Atlas | Stomach Adenocarcinoma | C17orf46 | 0.04 | 0.01 | lasso | 3 | 0.01 | 7.8e-02 | -6.2 | -6.1 | 1.2e-09 | 0.94 | 0.00 | 0.76 | FALSE |
| 7 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | MGC57346 | 0.11 | 0.12 | lasso | 2 | 0.11 | 1.1e-04 | -6.2 | 6.3 | 2.9e-10 | -0.88 | 0.01 | 0.91 | TRUE |