Best TWAS P=3.74e-14 · Best GWAS P=4.65e-15 conditioned to 0.0104
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Pancreas | RP5-1029K10.2 | 0.20 | 0.00 | enet | 49 | 0.06 | 2.3e-03 | -7.4 | -5.3 | 8.8e-08 | 0.34 | 0.05 | 0.50 | FALSE |
| 2 | METSIM | Adipose | ZNF652 | 0.05 | 0.03 | lasso | 8 | 0.05 | 6.2e-08 | 4.4 | 5.1 | 3.0e-07 | -0.69 | 0.11 | 0.89 | FALSE |
| 3 | The Cancer Genome Atlas | Colon Adenocarcinoma | ZNF652 | 0.09 | 0.01 | enet | 12 | 0.05 | 5.5e-04 | -7.0 | 5.4 | 7.1e-08 | -0.55 | 0.02 | 0.33 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | ZNF652 | 0.03 | 0.03 | enet | 5 | 0.03 | 2.6e-04 | -7.4 | 7.5 | 5.2e-14 | -0.90 | 0.02 | 0.94 | FALSE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ZNF652 | 0.06 | 0.03 | lasso | 4 | 0.02 | 1.6e-03 | -7.7 | 7.0 | 2.1e-12 | -0.76 | 0.01 | 0.97 | FALSE |
| 6 | The Cancer Genome Atlas | Lung Adenocarcinoma | ZNF652 | 0.05 | 0.02 | blup | 55 | 0.02 | 2.5e-03 | -7.8 | 7.6 | 3.7e-14 | -0.87 | 0.01 | 0.96 | TRUE |