Best TWAS P=3.07e-08 · Best GWAS P=2.89e-08 conditioned to 4.7e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Hypothalamus | PSMG1 | 0.46 | 0.20 | lasso | 5 | 0.16 | 1.5e-04 | 4.5 | 5.3 | 1.3e-07 | -0.06 | 0.14 | 0.80 | FALSE |
| 2 | GTEx | Esophagus Mucosa | BRWD1-IT2 | 0.08 | 0.06 | lasso | 5 | 0.06 | 3.9e-05 | -4.9 | -5.3 | 1.1e-07 | 0.09 | 0.07 | 0.91 | FALSE |
| 3 | GTEx | Lung | PSMG1 | 0.12 | 0.13 | lasso | 5 | 0.12 | 3.4e-09 | -5.5 | 5.5 | 3.2e-08 | -0.11 | 0.02 | 0.98 | FALSE |
| 4 | GTEx | Stomach | PSMG1 | 0.23 | 0.02 | lasso | 8 | 0.05 | 1.8e-03 | -4.7 | 5.5 | 3.7e-08 | -0.13 | 0.04 | 0.91 | FALSE |
| 5 | METSIM | Adipose | PSMG1 | 0.05 | 0.01 | bslmm | 638 | 0.02 | 3.6e-04 | 4.7 | 5.5 | 3.1e-08 | -0.19 | 0.08 | 0.91 | TRUE |