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chr20:61,522,825-62,912,463

Best TWAS P=1.59e-11 · Best GWAS P=6.4e-11 conditioned to 0.0235

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
9	GTEx	Whole Blood	STMN3	0.10	0.00	lasso	3	0.00	1.2e-01	5.5	-6.7	1.6e-11	-0.75	0.04	0.64	TRUE
4	GTEx	Brain Cortex	STMN3	0.25	0.09	lasso	7	0.11	6.8e-04	6.2	6.6	3.7e-11	0.86	0.04	0.87	FALSE
18	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	STMN3	0.07	0.01	blup	41	0.05	4.2e-04	6.4	6.5	6.8e-11	0.86	0.01	0.95	FALSE
11	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	STMN3	0.02	0.02	blup	43	0.02	1.7e-03	6.3	6.4	1.3e-10	0.91	0.01	0.90	FALSE
22	The Cancer Genome Atlas	Prostate Adenocarcinoma	ZGPAT	0.05	0.06	lasso	3	0.06	5.5e-07	6.4	-6.4	1.5e-10	-0.85	0.04	0.95	FALSE
12	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	TNFRSF6B	0.03	0.01	blup	44	0.02	7.1e-04	6.0	6.3	2.6e-10	0.86	0.03	0.90	FALSE
8	GTEx	Thyroid	SLC2A4RG	0.12	0.06	lasso	5	0.04	2.4e-04	6.0	-6.3	3.7e-10	-0.80	0.07	0.90	FALSE
14	The Cancer Genome Atlas	Brain Lower Grade Glioma	LIME1	0.02	0.03	blup	47	0.02	6.2e-03	6.2	6.2	4.8e-10	0.82	0.01	0.88	FALSE
16	The Cancer Genome Atlas	Lung Adenocarcinoma	TNFRSF6B	0.02	0.01	enet	7	0.01	6.9e-03	6.0	6.2	5.9e-10	0.81	0.05	0.62	FALSE
3	GTEx	Brain Cerebellum	STMN3	0.33	0.12	lasso	10	0.20	1.8e-06	5.9	6.1	8.1e-10	0.81	0.02	0.97	FALSE
13	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SLC2A4RG	0.03	0.01	blup	48	0.02	2.4e-03	6.0	-6.1	1.3e-09	-0.77	0.01	0.91	FALSE
1	CommonMind	Brain Pre-frontal Cortex	ARFRP1	0.07	0.07	lasso	3	0.06	5.3e-08	5.6	-6.1	1.4e-09	-0.77	0.23	0.77	FALSE
24	The Cancer Genome Atlas	Thyroid Carcinoma	LIME1	0.05	0.03	blup	47	0.04	3.9e-05	6.0	6.0	2.7e-09	0.75	0.04	0.95	FALSE
5	GTEx	Breast Mammary Tissue (Female)	GMEB2	0.36	0.06	lasso	4	0.05	1.2e-02	6.5	5.9	2.8e-09	0.92	0.01	0.92	FALSE
23	The Cancer Genome Atlas	Testicular Germ Cell Tumors	LIME1	0.10	0.02	blup	47	0.04	1.5e-02	5.5	5.9	3.6e-09	0.75	0.01	0.57	FALSE
2	CommonMind	Brain Pre-frontal Cortex	STMN3	0.07	0.02	lasso	4	0.05	2.8e-06	6.4	5.9	3.9e-09	0.73	0.02	0.97	FALSE
25	The Cancer Genome Atlas	Thyroid Carcinoma	ZGPAT	0.05	0.04	blup	60	0.03	2.3e-04	6.0	-5.8	5.8e-09	-0.82	0.03	0.96	FALSE
17	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	RTEL1	0.05	0.04	blup	56	0.03	4.2e-03	4.7	5.8	6.7e-09	0.75	0.03	0.45	FALSE
21	The Cancer Genome Atlas	Prostate Adenocarcinoma	SLC2A4RG	0.05	0.01	blup	48	0.02	2.0e-03	5.5	-5.7	9.1e-09	-0.64	0.04	0.80	FALSE
20	The Cancer Genome Atlas	Prostate Adenocarcinoma	LIME1	0.04	0.05	blup	47	0.05	9.0e-06	5.3	5.7	9.5e-09	0.69	0.18	0.80	FALSE
19	The Cancer Genome Atlas	Prostate Adenocarcinoma	ARFRP1	0.03	0.02	lasso	2	0.02	1.2e-03	5.6	-5.6	2.7e-08	-0.67	0.12	0.44	FALSE
7	GTEx	Testis	RTEL1	0.19	0.06	lasso	5	0.14	8.0e-07	6.2	5.5	3.2e-08	0.76	0.02	0.97	FALSE
6	GTEx	Cells Transformed fibroblasts	CTD-3184A7.4	0.09	0.00	enet	28	0.00	1.4e-01	4.4	5.4	6.5e-08	0.51	0.04	0.71	FALSE
10	YFS	Blood	LIME1	0.12	0.19	enet	15	0.19	5.3e-59	5.2	5.3	1.1e-07	0.64	0.87	0.13	FALSE
15	The Cancer Genome Atlas	Brain Lower Grade Glioma	ZGPAT	0.05	0.04	blup	60	0.05	7.2e-07	6.0	-5.3	1.1e-07	-0.78	0.03	0.97	FALSE