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chr2:60,466,491-62,123,953

Best TWAS P=6.42e-10 · Best GWAS P=4.66e-08 conditioned to 0.0283

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Visceral Omentum	AC016747.3	0.14	0.13	enet	15	0.16	7.6e-09	4.3	-5.6	2.3e-08	-0.33	0.56	0.42	FALSE
2	GTEx	Brain Cerebellar Hemisphere	AHSA2	0.35	0.22	enet	12	0.38	7.8e-11	-4.8	-5.6	2.7e-08	-0.26	0.32	0.65	FALSE
3	GTEx	Brain Cerebellum	KIAA1841	0.10	0.05	lasso	3	0.05	1.2e-02	-5.3	-5.2	2.2e-07	-0.25	0.10	0.65	FALSE
4	GTEx	Brain Cortex	AHSA2	0.25	0.13	enet	13	0.23	5.8e-07	4.7	-5.6	1.7e-08	-0.31	0.33	0.56	FALSE
5	GTEx	Brain Hippocampus	AHSA2	0.34	0.40	enet	17	0.35	5.9e-09	4.3	-5.2	1.6e-07	-0.28	0.47	0.49	FALSE
6	GTEx	Brain Nucleus accumbens basal ganglia	KIAA1841	0.17	0.16	lasso	3	0.18	1.7e-05	-4.7	-5.4	5.7e-08	-0.36	0.18	0.55	FALSE
7	GTEx	Brain Nucleus accumbens basal ganglia	AHSA2	0.44	0.34	enet	13	0.39	1.7e-11	4.1	-5.2	2.0e-07	-0.28	0.59	0.38	FALSE
8	GTEx	Brain Putamen basal ganglia	AHSA2	0.32	0.39	enet	14	0.36	2.6e-09	4.0	-5.4	7.4e-08	-0.28	0.56	0.40	FALSE
9	GTEx	Colon Transverse	AHSA2	0.24	0.25	lasso	10	0.32	7.8e-16	3.8	-5.3	1.3e-07	-0.37	0.69	0.29	FALSE
10	GTEx	Colon Transverse	AC010733.5	0.12	0.00	lasso	6	0.00	4.5e-01	4.5	-6.2	6.4e-10	-0.60	0.05	0.42	TRUE
11	GTEx	Esophagus Muscularis	NONOP2	0.07	0.00	enet	31	0.01	4.8e-02	5.3	-5.2	1.9e-07	-0.61	0.04	0.65	FALSE
12	GTEx	Heart Left Ventricle	AHSA2	0.13	0.08	lasso	8	0.07	1.2e-04	4.4	-5.5	4.1e-08	-0.32	0.34	0.62	FALSE
13	GTEx	Lung	RP11-493E12.2	0.06	0.04	lasso	3	0.01	2.6e-02	5.1	5.3	9.3e-08	0.65	0.04	0.86	FALSE
14	GTEx	Stomach	AHSA2	0.22	0.17	enet	21	0.24	1.0e-11	4.3	-5.3	1.4e-07	-0.29	0.58	0.40	FALSE
15	GTEx	Uterus	PUS10	0.34	0.21	lasso	8	0.14	7.4e-04	-4.4	-5.6	1.9e-08	-0.48	0.06	0.29	FALSE
16	ROSMAP	Brain Pre-frontal Cortex	PEX13	0.10	0.06	blup	330	0.10	1.7e-12	4.9	5.6	1.7e-08	0.80	0.03	0.96	FALSE
17	YFS	Blood	PEX13	0.01	0.00	blup	334	0.01	6.7e-03	-4.0	5.5	4.8e-08	0.49	0.10	0.40	FALSE
18	The Cancer Genome Atlas	Colon Adenocarcinoma	AHSA2	0.10	0.11	enet	10	0.11	4.1e-07	-5.0	-5.2	2.5e-07	-0.21	0.01	0.98	FALSE
19	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	PUS10	0.04	0.00	blup	64	0.03	3.8e-04	4.9	-5.8	5.2e-09	-0.64	0.02	0.44	FALSE
20	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	PEX13	0.06	0.03	lasso	3	0.04	1.3e-02	5.2	5.5	4.6e-08	0.54	0.01	0.78	FALSE
21	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	AHSA2	0.20	0.11	blup	39	0.22	3.5e-09	4.7	-5.1	2.8e-07	-0.23	0.02	0.96	FALSE
22	The Cancer Genome Atlas	Rectum Adenocarcinoma	C2orf74	0.44	0.28	enet	16	0.29	1.4e-07	4.7	5.1	2.8e-07	0.25	0.01	0.98	FALSE
23	The Cancer Genome Atlas	Skin Cutaneous Melanoma	PEX13	0.11	0.00	blup	40	0.03	6.6e-02	-4.4	6.0	2.0e-09	0.62	0.01	0.40	FALSE
24	The Cancer Genome Atlas	Testicular Germ Cell Tumors	AHSA2	0.25	0.20	enet	12	0.22	2.1e-08	4.7	-5.2	1.9e-07	-0.16	0.02	0.96	FALSE
25	The Cancer Genome Atlas	Thyroid Carcinoma	PEX13	0.03	0.03	enet	6	0.04	1.9e-04	5.1	5.6	2.6e-08	0.80	0.02	0.90	FALSE