[Hub]/) : Traits : Hayfever, allergic rhinitis or eczema :

chr1:7,686,056-9,637,591

Best TWAS P=1.21e-12 · Best GWAS P=8.03e-12 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SLC45A1 0.04 0.05 enet 9 0.02 1.8e-03 -5.2 -5.8 8.0e-09 0.79 0.65 0.29 FALSE
2 GTEx Adipose Subcutaneous RERE 0.20 0.23 lasso 2 0.24 1.7e-19 5.7 6.3 2.2e-10 -0.76 0.56 0.44 FALSE
3 GTEx Adipose Subcutaneous RP5-1115A15.1 0.14 0.07 enet 20 0.10 2.6e-08 -6.5 5.8 8.5e-09 -0.87 0.01 0.99 FALSE
4 GTEx Adipose Visceral Omentum RERE 0.22 0.17 lasso 5 0.17 5.2e-09 -6.8 6.0 1.9e-09 -0.91 0.00 1.00 FALSE
5 GTEx Breast Mammary Tissue RERE 0.19 0.08 enet 10 0.14 8.0e-08 6.0 5.6 2.1e-08 -0.70 0.19 0.79 FALSE
6 GTEx Breast Mammary Tissue RP5-1115A15.1 0.10 0.07 lasso 2 0.03 7.0e-03 5.7 5.7 9.3e-09 -0.62 0.15 0.77 FALSE
7 GTEx Breast Mammary Tissue (Male) RP5-1115A15.1 0.18 0.07 lasso 3 0.06 1.7e-02 -3.3 5.3 9.3e-08 -0.67 0.02 0.61 FALSE
8 GTEx Cells Transformed fibroblasts RERE 0.12 0.08 lasso 4 0.05 6.0e-05 5.9 6.0 2.6e-09 -0.66 0.24 0.75 FALSE
9 GTEx Esophagus Mucosa RERE 0.13 0.16 lasso 3 0.16 7.2e-11 -6.8 6.8 8.0e-12 -1.00 0.00 1.00 FALSE
10 GTEx Esophagus Mucosa RP5-1115A15.1 0.06 0.06 lasso 4 0.05 3.0e-04 -6.8 7.1 1.2e-12 -0.97 0.00 0.99 TRUE
11 GTEx Lung RERE 0.07 0.05 lasso 4 0.05 2.0e-04 -6.1 6.3 3.7e-10 -0.87 0.04 0.96 FALSE
12 GTEx Lung RP5-1115A15.1 0.05 0.08 lasso 1 0.07 1.0e-05 -6.5 6.5 6.3e-11 -0.98 0.01 0.98 FALSE
13 GTEx Nerve Tibial RERE 0.12 0.09 enet 16 0.11 5.6e-08 5.4 5.8 6.1e-09 -0.61 0.55 0.45 FALSE
14 GTEx Pancreas RERE 0.11 0.12 lasso 4 0.07 5.9e-04 5.9 6.4 1.8e-10 -0.63 0.06 0.82 FALSE
15 GTEx Skin Not Sun Exposed Suprapubic RP5-1115A15.1 0.08 0.04 enet 8 0.04 3.0e-03 -6.4 6.6 3.1e-11 -0.95 0.01 0.98 FALSE
16 GTEx Skin Sun Exposed Lower leg RERE 0.14 0.05 lasso 8 0.08 4.3e-07 -6.8 5.7 1.0e-08 -0.89 0.01 0.99 FALSE
17 GTEx Skin Sun Exposed Lower leg RP5-1115A15.1 0.07 0.03 enet 13 0.03 1.5e-03 -6.8 5.6 2.3e-08 -0.87 0.01 0.99 FALSE
18 GTEx Thyroid RP5-1115A15.1 0.09 0.12 lasso 2 0.09 1.5e-07 -6.5 6.7 2.2e-11 -0.98 0.01 0.99 FALSE
19 GTEx Whole Blood RERE 0.19 0.15 lasso 4 0.13 2.7e-12 -6.8 6.9 4.2e-12 -1.00 0.00 1.00 FALSE
20 METSIM Adipose RERE 0.08 0.12 lasso 17 0.13 1.8e-19 5.7 7.1 1.7e-12 -0.80 0.46 0.54 FALSE
21 NTR Blood RERE 0.04 0.04 lasso 8 0.03 2.0e-11 -6.5 6.2 5.5e-10 -0.87 0.04 0.96 FALSE
22 ROSMAP Brain Pre-frontal Cortex RERE 0.15 0.15 lasso 7 0.15 1.5e-18 5.9 6.1 9.7e-10 -0.71 0.44 0.56 FALSE
23 YFS Blood ENO1 0.07 0.06 lasso 7 0.06 5.1e-19 4.8 -5.4 6.3e-08 0.36 0.99 0.01 FALSE
24 YFS Blood RERE 0.09 0.15 lasso 4 0.16 5.7e-49 -6.7 6.9 6.7e-12 -0.97 0.01 0.99 FALSE
25 The Cancer Genome Atlas Breast Invasive Carcinoma RERE 0.02 0.03 lasso 2 0.03 4.7e-07 -6.7 6.4 1.7e-10 -0.96 0.00 0.99 FALSE
26 The Cancer Genome Atlas Esophageal Carcinoma RERE 0.10 0.07 blup 154 0.06 5.2e-03 -5.3 5.8 5.5e-09 -0.83 0.03 0.69 FALSE
27 The Cancer Genome Atlas Pancreatic Adenocarcinoma RERE 0.22 0.04 lasso 10 0.08 4.1e-04 -6.8 6.8 1.5e-11 -0.89 0.01 0.96 FALSE
28 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma RERE 0.12 0.01 enet 10 0.03 4.6e-02 -6.1 5.4 6.5e-08 -0.81 0.03 0.64 FALSE