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chr1:151,313,774-152,712,747

Best TWAS P=7.42e-20 · Best GWAS P=1.8e-19 conditioned to 0

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	The Cancer Genome Atlas	Colon Adenocarcinoma	LINGO4	0.29	0.07	enet	15	0.07	8.3e-05	5.94	9.1	7.4e-20	-0.28	0.06	0.12	TRUE
8	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	LINGO4	0.32	0.09	lasso	8	0.13	3.3e-06	5.94	6.7	1.6e-11	-0.21	0.07	0.28	TRUE
10	The Cancer Genome Atlas	Prostate Adenocarcinoma	THEM4	0.03	0.01	blup	59	0.01	9.8e-03	3.94	-5.7	1.4e-08	0.31	0.05	0.22	TRUE
5	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	LINGO4	0.24	0.07	lasso	4	0.11	1.7e-12	5.94	5.6	2.0e-08	0.03	0.98	0.00	TRUE
9	The Cancer Genome Atlas	Prostate Adenocarcinoma	LINGO4	0.53	0.20	lasso	4	0.23	1.1e-23	5.94	5.5	3.4e-08	0.04	1.00	0.00	TRUE
4	The Cancer Genome Atlas	Glioblastoma Multiforme	TDRKH	0.24	0.05	blup	49	0.05	1.0e-02	0.44	5.5	4.1e-08	-0.46	0.01	0.36	TRUE
1	GTEx	Colon Sigmoid	S100A11	0.18	0.13	lasso	3	0.14	1.1e-05	5.16	5.2	2.5e-07	-0.08	0.22	0.04	TRUE
7	The Cancer Genome Atlas	Lung Adenocarcinoma	LINGO4	0.20	0.07	lasso	4	0.07	3.7e-08	5.94	5.2	2.5e-07	0.00	1.00	0.00	TRUE
6	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	LINGO4	0.24	0.00	enet	10	0.09	9.5e-06	-0.01	6.4	1.6e-10	-0.08	0.02	0.04	FALSE
2	The Cancer Genome Atlas	Breast Invasive Carcinoma	LINGO4	0.15	0.03	lasso	4	0.05	8.9e-10	5.94	5.8	8.0e-09	0.02	0.96	0.00	FALSE
11	The Cancer Genome Atlas	Thyroid Carcinoma	LINGO4	0.43	0.15	lasso	7	0.20	2.3e-19	5.94	5.6	2.2e-08	0.04	1.00	0.00	FALSE