TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Hayfever, allergic rhinitis or eczema
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chr1:153,225,886-155,138,557
Best TWAS P=9.34e-12 · Best GWAS P=5.78e-14 conditioned to 0.000975
153.5M
154M
154.5M
155M
0
5
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
6
YFS
Blood
IL6R
0.04
0.04
lasso
3
0.04
5.1e-12
6.83
-6.8
9.3e-12
-0.95
0.01
0.99
TRUE
5
GTEx
Whole Blood
C1orf43
0.10
0.00
enet
37
0.00
2.8e-01
0.83
5.2
2.6e-07
0.24
0.05
0.11
TRUE
4
GTEx
Esophagus Muscularis
IL6R
0.10
0.00
enet
15
0.00
5.3e-01
6.94
-6.8
1.3e-11
-0.67
0.01
0.87
FALSE
3
GTEx
Colon Transverse
IL6R
0.18
0.06
lasso
3
0.06
9.2e-04
6.48
-6.4
1.3e-10
-0.92
0.09
0.79
FALSE
2
GTEx
Colon Sigmoid
IL6R
0.22
0.08
lasso
4
0.05
9.2e-03
6.83
-5.8
7.1e-09
-0.93
0.03
0.73
FALSE
1
GTEx
Adipose Subcutaneous
CRTC2
0.04
0.00
lasso
3
0.01
6.7e-02
2.45
-5.7
1.0e-08
-0.45
0.05
0.60
FALSE