TWAS
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Usage
Models
Genes
Traits
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Traits
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Cholesterol lowering medication
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chr9:106,846,396-108,380,721
Best TWAS P=2.79e-07 · Best GWAS P=3.1e-07 conditioned to 0.0639
106.8M
107M
107.2M
107.4M
107.6M
107.8M
108M
108.2M
108.4M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Cells Transformed fibroblasts
ABCA1
0.2
0.04
lasso
3
0.03
0.0016
-4.4
-5.1
2.8e-07
0.76
0.02
0.75
TRUE