[Hub]/) : Traits : Cholesterol lowering medication :

chr9:135,883,620-136,399,075

Best TWAS P=1.13e-09 · Best GWAS P=1.31e-09 conditioned to 0.00566

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 The Cancer Genome Atlas Breast Invasive Carcinoma ABO 0.07 0.08 lasso 3 0.08 5.0e-16 5.2 5.2 2.3e-07 0.63 0.02 0.98 FALSE
2 The Cancer Genome Atlas Esophageal Carcinoma ABO 0.27 0.13 lasso 2 0.11 1.8e-04 5.2 5.2 2.6e-07 0.63 0.01 0.97 FALSE
3 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma ABO 0.31 0.38 lasso 5 0.42 3.1e-26 5.5 5.2 1.6e-07 0.54 0.00 1.00 FALSE
4 The Cancer Genome Atlas Brain Lower Grade Glioma ABO 0.26 0.23 enet 10 0.26 6.0e-29 5.2 5.2 2.2e-07 0.66 0.02 0.98 FALSE
5 The Cancer Genome Atlas Liver Hepatocellular Carcinoma ABO 0.23 0.23 lasso 2 0.24 2.2e-11 5.5 5.5 2.9e-08 0.53 0.00 1.00 FALSE
6 The Cancer Genome Atlas Lung Adenocarcinoma ABO 0.21 0.25 lasso 5 0.25 2.1e-29 5.2 5.2 1.6e-07 0.59 0.01 0.99 FALSE
7 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma ABO 0.28 0.22 lasso 8 0.22 1.2e-14 5.2 5.3 1.5e-07 0.63 0.01 0.99 FALSE
8 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma ABO 0.23 0.23 lasso 3 0.23 2.0e-09 5.2 5.3 1.4e-07 0.61 0.00 0.99 FALSE
9 The Cancer Genome Atlas Rectum Adenocarcinoma ABO 0.48 0.23 enet 10 0.27 4.7e-07 5.7 6.1 1.1e-09 0.65 0.00 0.98 TRUE