TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Cholesterol lowering medication
:
←
→
chr11:63,044,593-64,701,030
Best TWAS P=1.64e-08 · Best GWAS P=1.78e-07 conditioned to 1
63M
63.2M
63.4M
63.6M
63.8M
64M
64.2M
64.4M
64.6M
0
2
4
6
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
ROSMAP
Brain Pre-frontal Cortex
VEGFB
0.10
0.07
enet
6
0.05
1.5e-07
5.2
-5.7
1.6e-08
-0.96
0.00
1.00
TRUE
1
CommonMind
Brain Pre-frontal Cortex
COX8A
0.06
0.00
bslmm
323
0.02
8.0e-04
2.0
-5.5
3.7e-08
-0.18
0.12
0.12
TRUE