Best TWAS P=3.66e-14 · Best GWAS P=7.05e-14 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 5 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | FNDC4 | 0.13 | 0.06 | lasso | 2 | 0.05 | 1.1e-03 | 7.5 | -7.6 | 3.7e-14 | -0.99 | 0.00 | 0.96 | TRUE |
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | FNDC4 | 0.24 | 0.09 | enet | 9 | 0.17 | 1.9e-16 | -4.1 | -5.9 | 3.4e-09 | -0.70 | 0.41 | 0.59 | FALSE |
| 4 | GTEx | Thyroid | FNDC4 | 0.24 | 0.10 | enet | 23 | 0.16 | 2.2e-12 | -3.9 | -5.8 | 4.9e-09 | -0.69 | 0.67 | 0.33 | FALSE |
| 1 | GTEx | Esophagus Muscularis | NRBP1 | 0.07 | 0.04 | lasso | 6 | 0.04 | 1.3e-03 | -4.3 | 5.8 | 6.0e-09 | 0.82 | 0.02 | 0.97 | FALSE |
| 7 | The Cancer Genome Atlas | Thyroid Carcinoma | GCKR | 0.18 | 0.08 | enet | 5 | 0.13 | 1.7e-12 | -3.9 | -5.7 | 1.4e-08 | -0.64 | 0.91 | 0.09 | FALSE |
| 3 | GTEx | Testis | AC074117.10 | 0.14 | 0.08 | lasso | 6 | 0.12 | 4.5e-06 | -3.4 | 5.6 | 1.9e-08 | 0.85 | 0.05 | 0.95 | FALSE |
| 2 | GTEx | Testis | NRBP1 | 0.16 | 0.09 | lasso | 3 | 0.06 | 1.8e-03 | -4.3 | 5.4 | 7.7e-08 | 0.80 | 0.03 | 0.96 | FALSE |