TWAS
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Traits
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Traits
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Medication: Blood pressure
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chr3:137,189,600-138,819,532
Best TWAS P=5.67e-08 · Best GWAS P=1.7e-07 conditioned to 1
137.2M
137.4M
137.6M
137.8M
138M
138.2M
138.4M
138.6M
138.8M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Brain Frontal Cortex BA9
DBR1
0.18
0.10
lasso
5
0.11
9.7e-04
5.1
5.4
5.7e-08
0.96
0.02
0.90
TRUE
3
The Cancer Genome Atlas
Brain Lower Grade Glioma
MRAS
0.03
0.01
blup
49
0.01
9.6e-03
4.7
-5.2
1.7e-07
-0.72
0.03
0.75
FALSE
1
GTEx
Artery Aorta
MRAS
0.52
0.53
lasso
5
0.54
2.5e-34
5.2
5.2
1.9e-07
1.00
0.00
1.00
FALSE