Best TWAS P=5.67e-08 · Best GWAS P=1.7e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | MRAS | 0.52 | 0.53 | lasso | 5 | 0.54 | 2.5e-34 | 5.2 | 5.2 | 1.9e-07 | 1.00 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Brain Frontal Cortex BA9 | DBR1 | 0.18 | 0.10 | lasso | 5 | 0.11 | 9.7e-04 | 5.1 | 5.4 | 5.7e-08 | 0.96 | 0.02 | 0.90 | TRUE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | MRAS | 0.03 | 0.01 | blup | 49 | 0.01 | 9.6e-03 | 4.7 | -5.2 | 1.7e-07 | -0.72 | 0.03 | 0.75 | FALSE |