[Hub]/) : Traits : Medication: Blood pressure : ← →

chr5:130,830,617-132,425,049

Best TWAS P=7.73e-08 · Best GWAS P=8.19e-08 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta P4HA2 0.12 0.14 lasso 2 0.11 1.2e-06 -5.2 -5.2 1.5e-07 0.97 0.01 0.99 FALSE
2 GTEx Artery Aorta P4HA2-AS1 0.08 0.03 lasso 3 0.01 6.6e-02 -5.3 -5.2 1.5e-07 0.99 0.02 0.95 FALSE
3 GTEx Artery Tibial P4HA2 0.12 0.15 lasso 6 0.14 3.2e-11 -5.4 -5.3 1.0e-07 0.99 0.01 0.99 FALSE
4 GTEx Esophagus Mucosa P4HA2 0.23 0.10 lasso 6 0.14 6.1e-10 -5.2 -5.2 1.5e-07 0.94 0.01 0.99 FALSE
5 GTEx Esophagus Mucosa SLC22A5 0.16 0.16 enet 8 0.16 6.3e-11 -5.2 5.4 7.7e-08 -0.95 0.01 0.98 TRUE
6 GTEx Lung SLC22A5 0.10 0.15 enet 11 0.13 3.4e-10 -5.2 5.2 2.2e-07 -0.94 0.02 0.98 FALSE
7 GTEx Skin Not Sun Exposed Suprapubic PDLIM4 0.13 0.08 lasso 2 0.06 2.6e-04 -5.2 5.2 2.2e-07 -0.84 0.04 0.93 FALSE
8 GTEx Skin Sun Exposed Lower leg PDLIM4 0.09 0.08 lasso 8 0.09 1.0e-07 -5.2 5.2 2.3e-07 -0.91 0.02 0.98 FALSE
9 GTEx Thyroid P4HA2 0.08 0.07 enet 9 0.06 3.5e-05 -5.4 -5.2 1.9e-07 0.98 0.01 0.99 FALSE
10 GTEx Whole Blood SLC22A5 0.09 0.12 lasso 2 0.10 1.7e-09 -5.2 5.2 1.7e-07 -0.90 0.01 0.99 FALSE
11 METSIM Adipose SLC22A5 0.05 0.08 lasso 1 0.08 1.0e-11 -5.2 5.2 1.7e-07 -0.90 0.02 0.98 FALSE
12 The Cancer Genome Atlas Breast Invasive Carcinoma SLC22A4 0.05 0.01 enet 7 0.02 1.6e-05 -5.2 5.4 7.7e-08 -0.83 0.01 0.97 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma P4HA2 0.21 0.35 enet 10 0.35 4.7e-35 -5.2 -5.2 1.9e-07 0.98 0.00 0.99 FALSE