Hub : Genes

SLC22A5

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.0550 0.0240 9.8e-04 0.040 NA 0.019 NA 0.038 3.1e-04 NA 1.0e-02 NA 4.2e-04
2 GTEx Artery Tibial 0.1842 0.0590 1.9e-06 0.123 NA 0.116 NA 0.110 7.5e-10 NA 2.5e-09 NA 6.1e-09
3 GTEx Brain Caudate basal ganglia 0.1920 0.1030 8.7e-03 0.032 NA 0.120 NA 0.085 4.2e-02 NA 2.7e-04 NA 2.0e-03
4 GTEx Brain Nucleus accumbens basal ganglia 0.1460 0.0750 8.0e-03 -0.001 NA 0.054 NA -0.005 3.4e-01 NA 1.4e-02 NA 4.6e-01
5 GTEx Brain Putamen basal ganglia 0.2660 0.0940 1.9e-04 0.050 NA 0.016 NA 0.072 2.5e-02 NA 1.3e-01 NA 8.8e-03
6 GTEx Breast Mammary Tissue 0.1040 0.0370 2.2e-05 0.020 NA 0.061 NA 0.060 3.2e-02 NA 4.5e-04 NA 5.2e-04
7 GTEx Breast Mammary Tissue (Male) 0.0863 0.0748 1.3e-01 0.077 NA 0.052 NA 0.058 7.8e-03 NA 2.5e-02 NA 1.8e-02
8 GTEx Breast Mammary Tissue (Female) 0.0443 0.0349 1.0e-01 -0.007 NA -0.008 NA 0.013 5.9e-01 NA 6.4e-01 NA 1.3e-01
9 GTEx Cells EBV-transformed lymphocytes 0.3690 0.0980 1.2e-06 0.046 NA 0.040 NA 0.105 1.3e-02 NA 2.0e-02 NA 2.8e-04
10 GTEx Cells Transformed fibroblasts 0.3240 0.0630 0.0e+00 0.279 NA 0.352 NA 0.354 4.7e-21 NA 2.0e-27 NA 1.6e-27
11 GTEx Colon Transverse 0.1170 0.0490 2.4e-04 0.070 NA 0.072 NA 0.029 3.1e-04 NA 2.5e-04 NA 1.5e-02
12 GTEx Esophagus Mucosa 0.1550 0.0460 5.2e-10 0.162 NA 0.161 NA 0.136 5.4e-11 NA 6.3e-11 NA 2.2e-09
13 GTEx Lung 0.1007 0.0312 1.7e-08 0.148 NA 0.131 NA 0.109 2.1e-11 NA 3.4e-10 NA 1.1e-08
14 GTEx Muscle Skeletal 0.0998 0.0434 3.5e-03 0.012 NA 0.006 NA 0.018 2.2e-02 NA 8.1e-02 NA 6.6e-03
15 GTEx Nerve Tibial 0.1695 0.0571 5.3e-05 0.106 NA 0.081 NA 0.091 6.0e-08 NA 2.4e-06 NA 5.5e-07
16 GTEx Skin Not Sun Exposed Suprapubic 0.1270 0.0420 2.0e-06 0.047 NA 0.051 NA 0.052 1.4e-03 NA 8.8e-04 NA 8.3e-04
17 GTEx Skin Sun Exposed Lower leg 0.2550 0.0660 3.6e-14 0.207 NA 0.186 NA 0.202 5.2e-17 NA 2.6e-15 NA 1.4e-16
18 GTEx Spleen 0.2560 0.0960 8.3e-04 0.280 NA 0.173 NA 0.281 6.8e-08 NA 3.4e-05 NA 6.6e-08
19 GTEx Stomach 0.0860 0.0420 5.4e-03 0.043 NA 0.010 NA 0.011 4.0e-03 NA 1.0e-01 NA 9.0e-02
20 GTEx Thyroid 0.1730 0.0650 2.1e-04 0.067 NA 0.116 NA 0.129 7.5e-06 NA 3.5e-09 NA 4.8e-10
21 GTEx Whole Blood 0.0860 0.0320 1.0e-05 0.119 NA 0.073 NA 0.100 4.5e-11 NA 2.8e-07 NA 1.7e-09
22 METSIM Adipose 0.0466 0.0170 8.8e-07 0.083 0.050 0.071 0.066 0.078 1.9e-12 5.0e-08 9.4e-11 4.1e-10 1.0e-11
23 NTR Blood 0.0241 0.0089 6.3e-05 0.010 0.014 0.015 0.014 0.017 2.6e-04 2.0e-05 8.3e-06 2.4e-05 2.3e-06
24 ROSMAP Brain Pre-frontal Cortex 0.0947 0.0290 1.7e-07 0.034 0.073 0.076 0.075 0.080 3.2e-05 9.9e-10 5.7e-10 6.5e-10 1.7e-10
25 YFS Blood 0.3835 0.0461 0.0e+00 0.362 0.353 0.368 0.369 0.365 2.2e-125 1.4e-121 4.2e-128 3.0e-128 1.2e-126
26 TCGA Breast Invasive Carcinoma 0.0522 0.0201 4.4e-16 0.073 0.083 0.085 NA 0.085 1.2e-14 1.6e-16 5.3e-17 NA 6.2e-17
27 TCGA Colon Adenocarcinoma 0.0750 0.0380 2.6e-04 0.037 0.065 0.060 NA 0.053 3.1e-03 1.2e-04 2.4e-04 NA 5.2e-04
28 TCGA Head and Neck Squamous Cell Carcinoma 0.0591 0.0247 1.4e-10 0.054 0.083 0.078 NA 0.075 1.1e-06 1.2e-09 3.9e-09 NA 9.2e-09
29 TCGA Kidney Renal Clear Cell Carcinoma 0.0580 0.0259 7.3e-05 0.040 0.044 0.031 NA 0.042 2.5e-05 8.9e-06 1.9e-04 NA 1.4e-05
30 TCGA Brain Lower Grade Glioma 0.1705 0.0552 0.0e+00 0.182 0.192 0.203 NA 0.191 3.3e-20 2.3e-21 1.4e-22 NA 3.2e-21
31 TCGA Lung Adenocarcinoma 0.0645 0.0382 4.7e-04 0.034 0.019 0.013 NA 0.023 6.6e-05 2.6e-03 9.9e-03 NA 9.3e-04
32 TCGA Lung Squamous Cell Carcinoma 0.0495 0.0242 1.7e-06 0.032 0.051 0.042 NA 0.047 1.2e-04 1.8e-06 1.4e-05 NA 4.6e-06
33 TCGA Ovarian Serous Cystadenocarcinoma 0.1180 0.0550 3.7e-05 0.036 0.068 0.051 NA 0.049 1.6e-03 2.2e-05 2.4e-04 NA 2.9e-04
34 TCGA Prostate Adenocarcinoma 0.1222 0.0708 4.1e-06 0.049 0.056 0.064 NA 0.077 6.3e-06 1.5e-06 2.8e-07 NA 1.8e-08
35 TCGA Rectum Adenocarcinoma 0.2690 0.1040 2.8e-06 0.214 0.199 0.240 NA 0.244 9.3e-06 2.0e-05 2.4e-06 NA 2.0e-06
36 TCGA Stomach Adenocarcinoma 0.0540 0.0320 3.5e-03 0.012 0.021 0.012 NA 0.020 4.6e-02 1.1e-02 4.2e-02 NA 1.2e-02
37 TCGA Thyroid Carcinoma 0.0290 0.0190 8.1e-03 0.019 0.007 0.001 NA 0.011 5.2e-03 6.0e-02 2.3e-01 NA 2.6e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37
Bipolar Disorder (2018) 1.2 1.9 4.3 1.0 1.8 1.3 -0.9 1.1 0.3 -0.8 -0.6 0.5 1.6 1.3 0.9 1.1 -1.3 1.7 1.5 1.6 -1.1 1.7 1.2 1.3 1.3 2.1 1.2 1.0 1.7 2.0 1.8 -0.4 0.5 1.4 1.9 1.9 1.2 2.1 1.9 1.4
Bipolar Disorder or Schizophrenia 1.1 2.7 5.9 1.7 2.4 1.6 -0.5 0.6 0.6 0.1 -0.6 1.1 2.1 1.8 1.5 1.6 -0.7 1.5 1.9 2.1 -1.8 2.1 1.6 2.0 2.0 1.3 1.0 1.8 1.9 2.3 2.0 -0.3 1.0 1.9 2.1 2.2 1.5 1.7 2.3 1.9
Depressed Affect (Nagel 2018) 1.2 2.6 6.7 -1.5 -1.5 -2.3 0.8 -0.1 -0.3 0.4 1.1 -0.2 -1.4 -2.2 -1.2 -1.0 2.0 -0.5 -2.0 -1.5 1.5 -2.2 -0.7 -1.6 -1.6 0.6 -0.0 -1.6 -2.6 -2.2 -2.3 -0.8 -1.5 -1.3 -2.4 -2.0 -2.1 -2.5 -2.5 -0.8
Depression (Nagel 2018) 2.1 3.2 8.9 -1.8 -1.6 -0.3 1.8 0.4 -1.3 -0.4 0.0 -0.9 -1.8 -2.2 -1.8 -1.6 1.5 -0.4 -2.7 -2.0 2.0 -2.2 -1.2 -2.0 -2.0 0.1 0.3 -1.9 -2.9 -2.5 -2.9 -0.3 -0.6 -1.5 -3.0 -1.7 -1.6 -2.9 -2.3 -1.6
Intelligence (Savage-Jansen 2018) 0.2 0.7 6.5 0.7 0.0 -1.0 0.9 0.3 -0.2 -0.9 0.6 0.8 0.4 0.0 0.4 0.7 2.6 0.0 -0.1 0.1 -0.2 -0.8 0.3 0.1 0.1 0.7 -0.2 0.1 -1.2 -0.9 -0.6 -0.5 -1.0 -0.5 -0.6 -1.3 -1.4 -1.3 -1.6 0.3
Neuroticism (Nagel 2018) 1.6 3.7 11.5 -2.0 -1.5 -1.9 0.9 -0.9 -0.3 1.0 0.9 -0.3 -1.6 -2.5 -1.6 -1.3 0.8 -0.1 -2.7 -2.0 2.0 -2.7 -0.6 -2.0 -2.0 0.8 0.4 -2.0 -3.3 -2.5 -3.1 -1.3 -1.6 -1.5 -3.3 -2.0 -2.1 -3.4 -2.8 -1.3
Schizophrenia (2018) 0.6 1.2 2.8 1.4 1.7 1.1 0.1 -0.1 0.5 0.8 -0.3 1.0 1.5 1.3 1.1 1.1 0.1 0.6 1.2 1.4 -1.4 1.3 1.1 1.5 1.5 -0.0 0.3 1.6 1.1 1.3 1.1 -0.0 0.8 1.4 1.2 1.3 1.0 0.5 1.4 1.3
Schizophrenia vs Biploar Disorder 0.6 0.8 2.8 1.0 1.0 0.6 0.4 0.5 -0.2 -0.7 0.1 1.4 1.2 0.7 1.0 0.8 1.7 -0.1 0.6 0.9 -1.4 1.0 0.9 1.4 1.4 -0.6 -0.7 1.5 0.9 0.7 0.7 -0.0 0.3 0.9 0.9 0.3 0.5 -0.1 0.7 0.9
Worry (Nagel 2018) 0.8 1.6 5.8 -1.4 -0.7 -0.4 0.8 -1.0 -0.6 1.2 -0.1 -0.4 -1.0 -1.4 -1.5 -1.0 -0.6 0.3 -2.1 -1.5 1.6 -1.6 -0.0 -1.5 -1.5 1.1 0.8 -1.5 -2.1 -1.3 -2.1 -1.1 -0.7 -0.6 -2.4 -0.5 -0.6 -2.4 -1.2 -1.0
Alzheimer’s Disease (in mother) 0.6 0.7 2.4 0.1 1.3 1.4 0.5 0.5 -0.4 0.4 -1.1 0.4 1.2 0.0 0.2 0.3 0.9 1.5 -0.1 0.6 -0.2 0.7 1.4 0.5 0.5 -0.1 0.9 0.4 0.6 0.9 0.2 -0.1 0.8 1.4 0.3 1.4 1.4 0.1 1.3 1.2
Alzheimer’s Disease (in father) 0.3 0.3 2.9 -0.0 0.2 -1.3 -1.7 -0.7 0.7 0.4 0.9 0.4 -0.1 -0.2 0.2 0.0 0.5 -0.1 -0.2 -0.1 -0.2 -0.2 0.0 0.1 0.1 0.9 0.1 0.2 -0.8 -0.2 -0.4 -0.8 -0.7 -0.0 -0.7 -0.0 0.1 -0.8 -0.6 -0.1
Alzheimer’s Disease (including proxy) 0.3 0.5 2.8 0.1 1.2 0.9 0.1 0.6 -0.5 0.3 -0.7 0.6 0.6 0.0 0.2 0.1 1.0 1.7 -0.8 0.1 0.1 0.3 1.3 0.3 0.3 0.8 1.2 0.3 -0.6 0.2 -0.6 -0.6 0.5 0.6 -0.7 0.9 0.6 -1.2 0.4 0.4
Crohns Disease (2017) 32.1 70.4 146.4 -11.4 -11.6 2.4 6.5 -0.4 -7.1 -2.6 -4.1 -9.4 -10.7 -11.2 -11.0 -10.8 -3.3 -7.9 -8.3 -10.3 9.7 -8.7 -9.9 -10.6 -10.6 -12.1 -4.1 -10.0 -6.6 -10.1 -8.3 6.8 2.2 -9.2 -7.3 -8.1 -5.6 -3.9 -6.8 -9.3
Irritable Bowel Disease (IBD) 22.2 52.8 121.0 -10.1 -9.7 2.5 6.0 -0.3 -5.5 -1.6 -2.9 -7.3 -9.3 -9.9 -9.3 -9.0 -2.1 -6.5 -7.2 -8.6 8.3 -7.3 -8.0 -9.0 -9.0 -11.0 -4.0 -8.3 -5.9 -9.2 -7.3 5.4 1.1 -8.6 -6.3 -8.0 -5.6 -3.9 -6.6 -8.3
Ulcerative Colitis (UC) 5.1 9.6 25.3 -4.6 -3.7 1.8 2.8 -0.2 -1.8 -0.0 -0.3 -2.5 -3.9 -4.2 -3.8 -3.6 -0.6 -2.4 -3.1 -3.4 3.4 -2.9 -2.7 -3.6 -3.6 -5.0 -1.9 -3.2 -2.7 -4.2 -3.2 2.0 -0.1 -4.1 -2.6 -4.1 -2.9 -2.0 -3.3 -3.7
Major Depression (MDD) 0.5 0.7 3.7 -1.7 -0.5 0.9 1.1 -0.4 0.2 1.3 0.1 -0.0 -0.4 -1.1 -0.8 -0.7 -0.2 -0.1 -0.7 -0.5 0.7 -0.8 -0.1 -0.7 -0.7 -0.7 -0.2 -0.9 -0.8 -1.2 -0.9 0.2 -0.3 -0.6 -0.5 -1.4 -1.9 -0.7 -1.1 -0.1
Reaction Time 0.2 0.4 1.6 -0.7 0.3 -0.7 0.0 0.1 0.8 0.9 0.1 0.6 -0.0 -0.5 -0.3 -0.1 -0.9 1.0 -0.2 0.0 -0.1 -0.4 0.7 0.2 0.2 1.1 1.0 0.7 -0.7 -0.0 -0.3 -1.3 -1.0 -0.5 -0.6 -0.1 -0.3 -0.5 -0.7 -0.1
Verbal and Numeric Reasoning (VNR) 0.3 0.8 3.6 1.0 0.4 -1.8 -0.7 -0.8 0.5 -0.4 1.9 1.4 0.8 0.7 1.2 1.3 1.5 -0.3 0.8 0.7 -1.0 -0.2 0.3 0.8 0.8 0.8 -0.8 0.8 0.0 0.3 0.3 -1.3 -1.5 0.5 0.0 -0.4 0.1 -0.5 -0.5 0.7
Breast Cancer 6.1 14.7 28.8 3.6 5.2 -0.9 -2.6 -0.3 3.6 1.3 1.4 3.5 5.1 3.8 4.4 4.2 1.9 2.9 4.2 4.8 -4.4 4.9 4.0 4.8 4.8 3.8 1.7 4.6 4.0 5.0 4.4 -1.2 0.6 5.4 4.3 4.5 3.7 3.1 4.3 5.0
Ovarian Cancer 0.3 0.4 1.4 0.8 0.1 -0.5 -1.0 -0.1 0.3 -1.0 0.1 0.0 0.3 0.5 0.4 0.5 1.1 -0.7 1.1 0.4 -0.7 1.2 -0.3 0.6 0.6 0.7 -0.5 0.4 0.6 0.5 0.9 0.5 0.2 0.3 0.9 0.2 0.3 1.0 0.2 0.5
Prostate Cancer 0.3 0.4 2.6 -0.1 0.0 -1.2 -0.9 -0.3 0.3 0.6 -0.3 0.3 -0.6 0.4 -0.0 -0.1 0.2 0.2 -0.5 -0.3 0.2 -0.6 -0.2 -0.2 -0.2 1.3 -0.0 -0.7 -0.9 -0.1 -0.7 -1.6 -0.9 -0.5 -1.1 -0.1 -1.0 -1.1 -0.5 -0.9
Age at First Birth 0.2 0.3 3.1 -0.9 0.1 0.2 -0.2 -1.8 0.4 1.4 -0.2 -0.2 -0.2 -0.7 -0.4 -0.4 -0.3 0.1 0.2 -0.1 0.3 0.5 -0.2 -0.2 -0.2 -0.3 -0.0 -0.1 0.3 0.4 0.2 -0.1 0.1 0.2 0.1 0.5 0.8 0.1 0.5 -0.4
Bipolar Disorder (2011) 0.4 0.4 2.4 -0.0 0.4 1.4 0.3 1.1 -0.7 -0.6 -0.9 -0.4 0.2 0.4 -0.2 -0.0 -1.5 1.0 0.1 0.2 0.4 0.4 0.8 -0.2 -0.2 0.4 1.0 -0.5 0.3 0.4 0.2 0.2 0.5 0.1 0.3 0.6 0.2 0.5 0.6 0.0
Body Mass Index (BMI) (2010) 0.6 0.8 3.0 1.0 0.6 1.4 0.8 -0.2 -0.5 -0.1 -0.3 -0.4 0.8 0.9 -0.3 0.2 -0.7 0.2 1.0 0.6 -0.2 1.3 0.3 0.3 0.4 0.5 0.6 0.2 1.0 1.2 1.2 0.8 1.1 1.0 1.2 1.5 1.4 1.7 1.4 0.8
Coronary Artery Disease (CAD) 1.2 1.4 7.3 0.6 1.1 2.2 0.3 0.8 -1.3 -1.0 -1.1 -0.1 1.1 0.4 -0.0 -0.0 0.4 -0.1 0.6 0.8 -0.8 1.6 0.2 0.8 0.8 -1.4 0.2 0.9 1.6 1.4 0.9 1.1 1.8 1.9 1.1 1.8 2.7 0.9 2.3 1.0
Crohns Disease (2012) 24.8 40.0 81.4 -8.1 -9.0 1.4 5.4 0.2 -5.7 -3.0 -2.9 -7.2 -7.9 -8.0 -8.3 -7.9 -1.4 -6.6 -6.3 -7.8 7.2 -6.5 -7.8 -8.0 -8.0 -8.7 -3.0 -7.5 -5.0 -7.7 -6.1 5.7 2.0 -6.8 -5.3 -6.1 -4.4 -2.6 -5.1 -6.7
Mean Putamen Volume 0.7 0.8 1.6 -0.8 -0.7 0.7 1.2 0.2 -0.7 -0.3 -0.1 -0.9 -0.8 -1.1 -1.0 -0.9 -0.8 0.5 -0.9 -1.0 1.2 -1.2 -0.2 -1.0 -1.1 0.3 0.5 -1.1 -1.1 -1.1 -1.0 0.2 -0.1 -1.2 -1.0 -0.9 -1.2 -0.4 -1.0 -1.0
Fasting Glucose 0.6 0.7 2.0 -1.1 -0.8 -0.6 -0.1 -1.1 0.0 0.1 -0.4 -0.2 -1.2 -1.4 -1.2 -1.2 0.0 -0.4 -0.6 -0.8 0.5 -1.0 -0.4 -0.5 -0.5 -0.2 -0.0 -0.5 -1.0 -0.9 -1.0 -0.6 -0.9 -1.1 -1.1 -1.0 -1.1 -0.7 -1.1 -1.1
HbA1C 0.2 0.2 1.9 -0.2 -0.0 0.4 0.4 1.4 0.1 -0.1 0.9 -0.4 0.0 -0.7 -0.3 -0.3 0.3 0.4 -0.3 0.3 1.1 -0.1 -0.2 -1.0 -1.0 -0.3 -0.3 -0.9 0.2 -0.2 -0.0 0.2 -0.1 0.1 0.0 -0.4 -0.2 -0.3 -0.2 0.4
HDL Cholesterol 1.3 2.1 7.3 -1.2 -0.2 0.1 1.1 0.4 -0.1 0.3 0.5 0.2 -1.1 -1.2 -0.8 -0.9 0.6 1.6 -2.0 -1.0 1.2 -2.0 0.6 -0.9 -0.9 1.0 1.3 -1.0 -2.5 -1.8 -2.2 -1.7 -1.4 -2.0 -2.4 -1.6 -2.5 -2.7 -2.3 -1.4
LDL Cholesterol 1.2 1.9 6.0 -0.6 -2.0 -1.1 -0.4 0.1 -2.2 -1.4 -0.5 -1.8 -1.3 -1.5 -1.7 -2.0 -1.4 -2.0 -1.0 -1.5 1.3 -1.7 -2.4 -1.7 -1.7 -0.5 -1.0 -1.8 0.2 0.2 -0.8 -0.3 -0.1 0.5 -1.4 0.9 2.4 0.3 0.7 -1.2
Lupus 2.4 3.6 7.5 -2.7 -2.3 -0.7 0.8 -1.1 -1.3 0.9 -0.3 -1.1 -2.6 -2.4 -1.8 -2.3 0.4 -1.3 -2.4 -2.3 1.9 -2.7 -1.7 -2.1 -2.1 -1.5 -0.9 -2.1 -2.1 -2.4 -2.5 -0.1 -0.5 -2.3 -2.4 -2.2 -1.7 -2.3 -2.0 -2.6
Neuroticism (2016) 0.9 1.2 5.5 -0.9 -0.7 -2.1 -0.3 -1.3 0.6 1.5 2.4 0.3 -0.6 -1.4 -0.7 -0.1 2.0 -0.6 -0.6 -0.6 0.4 -1.0 -0.2 -0.5 -0.5 0.5 -0.4 -0.5 -1.4 -1.0 -1.0 -1.1 -1.4 -1.1 -1.2 -1.2 -2.1 -1.3 -1.5 -0.5
Primary Biliary Cirrhosis 0.1 0.1 0.5 0.6 -0.3 -0.5 -0.2 -0.6 0.6 0.5 -0.5 0.3 -0.0 0.4 0.4 0.4 -0.3 -0.4 0.5 0.3 -0.2 -0.1 -0.3 -0.0 -0.0 0.3 -0.7 -0.2 0.4 0.1 0.4 -0.2 -0.5 -0.3 0.3 -0.4 -0.4 0.5 -0.2 -0.1
Rheumatoid Arthritis 1.3 1.8 8.3 0.9 2.4 1.2 0.4 -0.8 1.3 1.5 0.7 2.6 1.7 1.1 1.3 1.6 0.0 2.0 0.7 1.7 -1.5 0.7 2.9 1.8 1.8 0.9 0.8 1.8 0.1 0.7 0.3 -1.9 -1.1 0.8 0.4 0.2 -0.2 -1.0 0.0 1.0
Schizophrenia (2014) 0.8 1.8 4.1 1.5 2.0 1.4 -0.2 0.0 0.9 0.6 -0.5 1.5 1.7 1.8 1.3 1.4 0.5 1.0 1.5 1.7 -1.8 1.6 1.4 1.9 1.9 0.7 0.2 1.8 1.5 1.6 1.5 -0.4 0.5 1.3 1.6 1.3 0.8 0.8 1.6 1.3
Triglycerides 3.7 6.0 12.3 2.5 2.0 -1.1 -2.2 -0.9 2.4 0.4 2.0 2.3 2.9 2.5 2.6 2.7 1.1 -0.8 3.4 3.0 -3.3 3.0 0.8 3.0 3.0 -0.3 -1.9 2.9 3.5 3.1 3.5 0.1 -0.2 3.1 3.4 1.8 3.1 2.5 2.5 2.8
Type 2 Diabetes (T2D) (2012) 0.5 0.6 3.2 1.0 1.2 0.3 0.8 -0.1 0.6 1.2 0.7 1.1 0.7 0.4 0.7 0.9 1.8 0.7 0.7 1.0 -0.8 0.4 1.1 0.9 0.9 0.1 -0.3 0.6 -0.3 0.2 0.1 -1.1 -1.0 0.3 0.1 -0.3 -0.4 -0.4 -0.2 0.5
Ulcerative Colitis 5.8 8.4 27.5 -4.2 -3.8 0.5 1.8 -1.1 -1.6 0.4 -0.7 -2.5 -4.0 -4.4 -3.7 -3.4 -0.4 -3.2 -2.4 -3.1 3.1 -2.4 -3.3 -3.5 -3.5 -5.2 -2.8 -3.4 -1.6 -3.3 -2.5 1.8 -0.3 -3.7 -2.2 -3.4 -1.6 -1.3 -2.5 -4.0
Blood Eosinophil Count 77.8 599.1 1156.0 25.3 30.8 -14.2 -22.4 -13.1 34.0 22.4 21.8 33.2 27.9 24.0 29.3 32.3 26.3 14.8 29.8 32.3 -31.9 23.5 24.9 32.7 32.7 24.7 -1.4 31.6 20.3 25.7 26.1 -21.4 -15.3 20.0 23.5 12.2 10.7 10.2 12.0 22.8
Blood Platelet Count 11.7 135.8 246.5 13.7 13.7 -5.5 -9.9 -4.2 11.2 4.5 10.4 13.3 13.3 12.3 14.1 13.7 2.9 3.1 15.2 15.7 -15.7 13.1 9.7 15.5 15.5 9.1 -2.4 14.8 13.5 15.2 14.7 -7.7 -4.0 12.4 13.3 9.7 11.0 8.7 10.3 11.5
Blood Red Count 0.3 2.8 6.8 1.4 2.5 1.2 -0.1 0.0 0.8 0.7 0.3 1.2 2.4 1.4 1.4 1.6 -0.7 1.8 1.8 2.1 -1.7 2.1 2.6 2.1 2.1 1.4 1.3 1.7 1.9 2.3 1.8 -0.9 0.4 2.2 1.9 2.1 1.6 1.4 2.2 2.0
Blood White Count 18.7 138.4 246.5 13.9 14.7 -0.3 -5.5 -2.2 9.7 4.7 7.0 12.2 15.3 13.4 13.9 14.4 5.8 4.9 14.9 15.5 -15.2 15.5 11.3 15.7 15.7 6.4 -0.1 15.3 13.7 14.3 14.8 -2.4 0.7 13.7 15.0 10.1 9.5 9.8 11.6 14.4
Heel T-Score 0.6 4.9 18.4 2.8 2.0 0.8 -0.2 0.5 -0.7 0.1 0.9 1.2 2.6 2.5 2.9 2.4 0.1 -0.1 2.3 2.3 -2.2 2.8 1.4 2.2 2.2 -0.8 -0.7 2.2 3.2 2.9 2.6 0.9 1.7 3.6 2.6 2.8 4.3 2.2 3.4 2.7
BMI 0.4 2.6 10.3 2.1 1.1 -0.3 0.1 0.2 0.4 -1.1 0.8 0.4 1.4 1.9 1.1 1.3 -1.1 0.1 2.6 1.7 -1.5 2.5 0.9 1.5 1.5 2.3 0.4 0.9 2.4 2.4 2.8 0.1 0.3 1.2 2.6 1.9 1.6 3.2 1.8 1.4
Height 14.0 270.0 483.3 -19.2 -18.3 8.2 13.1 7.2 -16.6 -9.1 -16.0 -18.8 -19.3 -18.9 -21.5 -21.0 -7.8 -3.1 -21.5 -21.9 22.0 -18.8 -12.4 -21.5 -21.5 -7.8 5.6 -21.9 -19.3 -19.7 -20.2 7.8 4.7 -17.5 -19.3 -11.4 -14.9 -11.8 -13.9 -16.8
Waist Hip Ratio (WHR) 0.6 2.7 6.2 -1.7 -1.9 0.1 0.7 0.6 -1.6 -1.4 -1.2 -1.4 -2.2 -1.8 -1.6 -1.6 -0.2 -1.0 -2.4 -1.9 1.8 -2.5 -1.8 -2.0 -2.0 -0.9 -0.8 -2.2 -1.6 -1.9 -2.3 -0.3 -0.5 -1.2 -2.3 -1.5 -1.3 -1.8 -1.3 -2.1
Systolic Blood Pressure 0.5 2.5 7.7 1.8 1.4 0.0 -0.5 -0.5 0.0 -0.6 -0.4 0.6 1.6 1.4 1.2 1.0 -0.9 -0.2 1.8 1.7 -1.5 2.3 0.3 1.5 1.5 0.7 -0.9 1.0 2.8 2.6 2.2 -0.1 0.4 2.6 2.1 2.1 2.8 1.9 2.6 1.8
Smoking Status 0.7 1.7 5.6 -1.1 -2.2 -1.6 -0.5 -0.3 -1.0 -1.7 -0.5 -1.3 -1.9 -2.0 -1.6 -1.6 -0.0 -2.3 -0.5 -1.4 1.1 -1.2 -2.4 -1.5 -1.5 -1.5 -1.4 -1.6 -0.4 -1.0 -0.5 0.9 -0.0 -1.5 -0.7 -0.9 -0.0 0.4 -0.9 -1.6
Allergy or Eczema 5.1 13.3 26.2 4.4 5.1 -0.9 -2.2 -0.4 3.2 2.1 2.4 5.1 4.5 3.6 4.8 4.8 4.2 3.2 3.8 4.7 -4.6 3.5 4.6 4.9 4.9 4.0 0.3 4.1 3.3 4.3 3.5 -3.4 -1.7 3.8 3.1 2.8 3.0 1.1 2.8 3.4
Cardiovascular Disease 2.9 9.5 25.0 4.1 4.1 -1.6 -2.5 0.6 3.0 0.5 1.6 3.7 3.9 3.5 3.9 3.8 2.1 2.4 3.2 3.8 -4.0 3.3 3.2 4.2 4.2 5.0 0.8 3.7 2.4 3.6 3.3 -2.6 -1.3 3.0 2.9 2.4 1.2 1.5 2.0 3.4
Hypothyroidism (self reported) 1.5 3.5 7.1 -2.6 -1.6 1.8 1.2 -1.6 -1.0 0.6 0.4 -1.0 -2.4 -2.4 -2.2 -2.2 -2.4 -0.5 -2.4 -2.1 1.9 -1.8 -1.0 -1.8 -1.8 -2.2 -0.6 -1.6 -2.2 -2.5 -2.4 0.2 -0.3 -2.7 -2.1 -2.4 -1.8 -2.2 -2.2 -2.5
Respiratory disease 23.2 51.5 109.7 8.3 10.2 -0.1 -3.1 1.3 5.4 3.2 1.9 8.7 9.7 8.3 8.8 9.4 10.5 6.5 6.5 8.8 -8.8 8.0 8.9 9.6 9.6 7.8 2.5 8.7 6.1 8.0 6.9 -3.9 -0.5 8.3 6.6 6.3 5.3 2.6 6.2 8.3
Type 2 Diabetes (T2D) (2018) 0.6 1.0 4.2 0.2 0.5 -0.0 0.6 1.0 0.1 -0.3 -0.8 -0.4 0.9 -0.2 0.1 0.4 0.9 -0.4 1.0 0.6 -0.7 1.6 -0.2 0.7 0.7 -0.6 0.1 0.5 1.6 1.2 1.4 1.5 1.5 1.4 1.5 1.5 1.2 2.0 1.8 1.4
Lung FEV1/FVC ratio 11.7 59.5 130.0 -7.9 -10.9 -5.3 2.6 -5.5 -1.9 0.9 2.3 -5.4 -10.3 -8.7 -7.9 -7.8 -2.5 -9.1 -5.5 -8.0 7.0 -9.8 -10.0 -8.6 -8.6 -8.2 -7.4 -8.1 -7.5 -10.1 -7.6 0.7 -5.0 -10.4 -7.7 -11.4 -8.8 -5.7 -10.6 -9.3
Lung FVC 6.6 33.8 68.0 6.7 8.0 -1.9 -5.3 -2.2 8.2 4.1 5.8 7.9 6.7 6.7 8.2 8.2 0.3 5.3 6.6 7.9 -7.2 5.0 7.4 7.7 7.7 6.7 1.2 7.8 3.8 5.4 5.5 -5.6 -3.7 4.3 5.2 2.3 0.6 1.6 2.1 5.6
Neuroticism 1.0 2.4 7.2 -1.7 -1.3 -1.3 1.0 -0.9 -0.1 1.0 1.2 0.0 -1.5 -2.3 -1.3 -0.9 0.8 -0.6 -1.9 -1.4 1.5 -2.0 -0.5 -1.5 -1.5 -0.1 -0.4 -1.4 -2.4 -2.1 -2.3 -0.8 -1.4 -1.4 -2.3 -2.0 -1.7 -2.7 -2.4 -1.3
Chronotype (morning person) 0.8 1.8 7.3 2.7 1.3 -0.0 -0.4 0.8 0.0 -0.9 0.2 0.7 1.9 2.4 2.0 1.8 1.3 0.7 1.0 1.2 -1.3 1.4 1.1 1.3 1.3 1.6 1.0 1.2 1.0 1.3 1.0 0.4 0.9 1.8 1.2 1.6 1.1 0.8 1.5 1.8
Hair Pigment 0.0 1.3 5.1 0.2 1.8 1.4 0.4 -0.7 1.3 1.7 -0.4 1.7 1.5 0.6 0.8 1.0 0.5 1.9 0.4 1.2 -1.2 0.8 2.2 1.5 1.5 1.3 1.5 1.6 0.4 1.1 0.6 -0.9 0.3 1.3 0.6 1.0 -0.1 -0.1 0.8 1.4
Tanning 0.1 1.0 3.5 0.4 0.2 1.8 1.1 1.8 -1.2 -1.5 -1.9 -1.2 0.5 -0.0 -0.3 -0.2 -0.7 1.9 -0.2 -0.2 0.8 0.6 0.9 -0.3 -0.3 0.1 1.8 -0.6 0.8 0.7 0.5 0.9 1.5 0.8 0.7 1.3 0.9 1.1 1.3 1.1
Hand grip strength (left) 11.8 31.0 55.1 -7.3 -6.7 1.2 2.9 0.2 -4.3 -0.6 -4.2 -6.3 -7.0 -6.8 -7.3 -7.3 -3.6 -2.2 -7.0 -7.3 7.4 -6.8 -4.9 -7.4 -7.4 -3.7 0.7 -7.4 -6.4 -6.7 -6.9 1.9 0.7 -6.0 -6.8 -4.3 -4.4 -4.3 -5.0 -6.1
Number of treatments/medications taken 4.9 8.8 16.3 3.6 3.6 -2.1 -1.7 -0.5 3.1 2.2 2.0 3.7 3.7 3.2 3.9 4.0 3.5 1.4 3.3 4.0 -4.0 2.7 2.5 4.0 4.0 2.8 -0.6 3.5 3.0 3.5 3.2 -2.6 -1.8 3.2 2.9 1.9 1.9 1.5 2.1 3.1
Average weekly spirits intake 0.2 0.2 1.0 0.9 -0.0 -0.4 0.6 -0.3 -0.9 -0.3 0.9 -0.3 0.1 0.3 0.4 0.1 0.9 -0.0 -0.6 -0.3 0.3 -0.0 -0.2 -0.3 -0.3 1.0 0.5 -0.3 -0.5 -0.1 -0.5 0.1 0.5 0.5 -0.5 0.5 -0.0 -0.3 0.2 0.3
Sensitivity / hurt feelings 1.6 2.8 6.8 -2.1 -2.1 -1.0 0.2 -0.6 -1.2 -0.6 1.2 -1.1 -2.0 -2.6 -2.2 -2.0 -0.2 -1.5 -1.7 -2.0 1.9 -2.3 -1.6 -2.0 -2.0 -1.3 -1.0 -1.9 -1.8 -2.0 -2.0 -0.3 -1.1 -1.6 -2.2 -1.8 -1.1 -1.8 -1.9 -1.9
Frequency of depressed mood in last 2 weeks 3.8 5.4 11.7 -2.8 -2.8 -1.5 0.9 -0.4 -0.8 -0.1 -0.4 -1.4 -2.6 -3.4 -2.9 -2.4 1.3 -1.5 -2.8 -2.7 2.7 -3.1 -2.4 -3.0 -3.0 -0.3 -0.7 -3.1 -3.0 -2.8 -3.0 -0.5 -1.5 -2.2 -3.4 -2.4 -1.8 -2.7 -3.0 -2.2
Hearing difficulty/problems: Yes 0.4 0.5 3.9 0.6 1.0 0.3 0.1 0.5 -0.0 -0.2 0.4 0.1 1.1 0.9 0.6 0.7 0.2 1.3 -0.1 0.4 -0.3 0.8 0.8 0.6 0.6 2.0 1.3 0.4 -0.2 0.6 0.0 -0.5 0.3 1.3 0.1 1.0 0.1 0.0 0.5 1.4
Relative age of first facial hair 2.1 4.3 12.2 2.1 3.2 1.2 -0.0 0.3 1.5 0.5 -0.2 2.7 3.2 2.2 2.1 2.5 3.4 2.7 1.3 2.3 -2.1 2.5 3.5 2.6 2.6 2.0 1.7 2.6 1.0 1.7 1.4 -0.3 0.5 2.6 1.6 1.7 1.2 0.2 1.5 3.0
Other serious medical condition/disability diagnosed by doctor 0.5 0.7 3.8 0.7 0.7 -0.2 0.2 -0.4 0.7 0.3 0.8 0.7 1.0 0.7 0.8 1.1 1.9 -0.4 1.0 1.1 -1.1 1.0 0.2 1.0 1.0 -0.2 -0.9 1.0 1.1 0.6 1.0 0.3 -0.2 0.6 1.2 -0.1 0.5 0.8 0.4 0.9
Ever used hormone-replacement therapy (HRT) 0.2 0.2 1.6 0.8 0.6 1.1 1.3 -0.5 -0.5 0.5 0.2 0.3 0.4 0.8 0.6 0.4 -0.7 0.5 0.0 0.3 -0.2 0.2 0.6 0.3 0.3 -0.5 0.1 0.3 0.3 0.2 0.0 -0.0 0.2 0.5 0.3 0.1 0.1 -0.0 0.5 0.4
Ever had hysterectomy (womb removed) 0.6 0.6 4.0 0.5 -0.2 -0.8 -0.4 -0.8 0.4 -0.0 2.0 1.2 -0.3 -0.1 0.3 -0.2 0.1 -0.9 0.2 0.3 -0.5 -0.8 -0.1 0.3 0.3 -0.0 -1.5 0.6 -0.3 -0.4 -0.2 -1.5 -2.0 -0.4 -0.3 -1.4 -0.8 -1.0 -1.1 -0.3
Systolic blood pressure, automated reading 0.3 0.8 2.7 0.7 -0.2 0.3 1.3 0.7 -1.7 -1.5 -0.8 -0.7 0.5 0.5 0.2 -0.1 0.1 -1.0 0.1 0.1 -0.2 1.0 -0.8 0.1 0.1 -0.5 -0.7 -0.1 1.3 0.8 0.8 1.3 1.2 1.4 0.9 1.0 1.6 1.1 1.4 1.1
Eye problems/disorders: Diabetes related eye disease 1.5 1.6 4.6 -1.6 -1.9 -0.5 0.9 0.5 -0.9 -1.1 -0.9 -1.5 -1.6 -2.0 -1.7 -1.4 0.6 -1.6 -1.1 -1.6 1.4 -0.9 -2.1 -1.7 -1.7 -1.2 -0.7 -1.9 -0.7 -1.4 -0.8 1.6 0.6 -1.3 -0.7 -1.0 -1.0 0.1 -0.8 -1.1
Angina 1.1 1.4 4.2 1.1 1.2 1.0 1.5 1.3 -0.7 -1.2 -0.4 0.4 1.8 1.1 0.5 0.7 1.9 0.2 0.8 1.1 -1.0 2.0 0.7 1.1 1.1 0.7 0.7 1.3 1.1 1.1 1.1 1.1 1.4 1.6 1.4 1.4 1.1 0.9 1.5 1.9
Medication for hormone replacement therapy 1.2 1.3 6.1 1.5 0.7 0.6 -0.6 0.2 -0.0 -1.2 -0.2 -0.2 1.1 1.1 0.6 0.9 -1.1 -0.3 1.5 1.2 -0.7 1.6 0.4 0.8 0.8 0.5 -0.3 0.2 2.1 1.7 1.9 0.4 0.5 1.2 2.0 1.4 0.9 2.5 1.8 1.2
Vitamin and mineral supplements 0.5 0.7 3.4 1.2 0.8 -1.0 -1.2 0.6 0.9 -0.2 0.5 0.5 1.0 0.9 1.2 1.1 -0.2 0.3 1.0 0.8 -0.8 0.8 0.5 0.8 0.8 1.9 0.5 0.7 0.6 1.0 0.9 -0.3 0.0 0.7 0.7 0.9 0.5 0.8 0.6 0.9
Supplements: Zinc 0.6 0.6 2.6 -0.0 -0.8 1.6 0.6 -0.2 -1.0 -1.3 -1.2 -0.8 -0.3 -0.4 -0.9 -0.8 -1.6 0.4 -0.8 -0.8 1.1 -0.8 -0.1 -0.9 -0.9 0.4 0.2 -1.5 -0.3 -0.5 -0.4 -0.3 -0.5 -0.6 -0.4 -0.6 -0.8 0.0 -0.5 -0.4
Medication: Co-codamol 0.8 0.9 7.7 -0.3 -0.6 0.5 0.7 0.5 -1.0 -0.9 -1.6 -1.3 0.1 -0.3 -0.5 -0.3 1.2 -1.2 0.0 -0.6 0.4 0.8 -1.3 -0.5 -0.5 -1.1 -0.1 -0.6 0.5 -0.1 0.4 2.8 2.3 0.5 0.7 0.7 0.4 1.1 0.9 0.4
Medication: Metformin 1.5 2.1 9.5 0.6 0.8 -0.8 -0.4 0.7 0.6 -0.1 -0.5 -0.3 1.1 0.4 0.8 0.9 -0.2 -0.4 2.0 1.3 -1.3 2.0 -0.2 1.2 1.2 -0.1 -0.1 0.9 2.6 2.3 2.4 1.0 1.1 1.9 2.3 2.1 2.2 3.1 2.5 1.5
Diabetes (father) 0.4 0.6 3.9 0.2 -0.5 -1.3 -0.5 -1.1 0.2 1.8 0.3 -0.1 -0.1 -0.1 -0.3 0.2 2.0 -1.5 0.4 0.0 -0.1 0.6 -1.0 -0.1 -0.1 -1.0 -1.2 -0.3 0.8 0.5 0.6 0.4 0.1 0.4 0.4 0.2 0.9 0.6 0.5 0.1
Diabetes (mother) 0.7 0.9 3.8 -0.1 1.0 -1.0 -1.8 -1.0 1.9 1.3 0.1 1.4 0.8 0.1 0.9 0.9 0.0 0.7 0.8 1.0 -1.1 0.4 0.8 1.1 1.1 0.3 -0.3 0.9 0.8 1.1 0.8 -1.8 -1.3 0.9 0.5 0.3 1.0 -0.0 0.3 0.8
Severe depression (siblings) 0.3 0.4 0.9 0.5 0.9 0.4 -0.6 -0.5 0.6 -0.3 0.4 0.6 0.9 0.4 0.6 0.7 0.1 0.8 0.7 0.8 -0.7 0.7 1.0 0.8 0.8 0.6 0.3 0.7 0.5 0.5 0.6 -0.3 -0.3 0.6 0.8 0.2 0.0 0.4 0.4 0.9
Pack years adult smoking proportion 1.7 2.6 13.1 -1.3 -1.4 2.0 3.6 0.7 -2.4 -1.1 -2.0 -1.4 -1.2 -2.0 -1.7 -1.7 0.7 -0.5 -2.1 -1.7 1.7 -1.3 -0.9 -1.7 -1.7 -2.5 0.1 -1.7 -1.5 -2.0 -1.9 1.4 1.1 -0.8 -1.4 -1.2 -1.5 -1.4 -0.9 -0.7
Impedance of leg (right) 0.9 4.1 9.5 1.9 2.7 0.7 -1.7 0.8 1.3 -0.1 0.9 2.6 2.6 2.4 2.9 2.7 0.1 1.4 2.0 2.6 -2.7 2.0 2.1 2.8 2.8 0.1 -0.2 3.1 2.3 2.4 1.9 -0.8 0.0 2.9 2.1 1.7 2.4 0.8 2.3 2.2
Leg fat-free mass (left) 8.2 43.7 89.5 -7.2 -7.6 2.1 5.6 2.6 -6.4 -3.8 -6.2 -7.8 -8.1 -7.6 -9.1 -8.6 -3.7 -1.4 -8.0 -8.6 8.9 -7.5 -5.1 -8.8 -8.8 -1.4 2.2 -9.5 -7.7 -7.6 -7.6 2.2 0.9 -7.9 -7.5 -4.7 -6.4 -3.9 -6.1 -7.2
Trunk fat percentage 0.1 0.4 4.6 0.1 -0.2 0.9 2.1 0.3 -0.7 -0.9 -0.7 -0.7 -0.1 -0.2 -0.6 -0.1 -1.0 0.5 0.5 -0.1 0.2 0.2 0.2 -0.1 -0.1 0.9 0.7 -0.4 0.0 -0.1 0.4 0.7 0.5 -0.5 0.6 -0.1 -0.8 1.1 -0.1 0.0
Hand grip strength (right) 12.8 34.8 63.2 -8.0 -7.1 1.6 2.8 0.3 -4.7 -1.6 -3.8 -6.6 -7.6 -7.6 -7.8 -7.7 -4.8 -2.7 -7.3 -7.7 7.7 -6.9 -5.2 -7.8 -7.8 -4.2 0.2 -7.9 -6.5 -6.9 -7.0 1.8 0.5 -6.6 -7.0 -4.6 -4.3 -4.5 -5.2 -6.8
Townsend deprivation index at recruitment 0.2 0.3 1.3 0.4 0.9 1.1 0.1 -0.3 0.6 0.7 -0.1 0.6 0.7 0.5 0.6 0.4 -0.1 0.7 0.4 0.7 -0.4 0.6 1.1 0.6 0.6 0.4 0.3 0.5 0.4 0.4 0.5 -0.1 0.1 0.5 0.7 0.2 -0.1 0.4 0.4 0.8
Current tobacco smoking 0.9 1.5 4.5 -1.0 -1.7 0.5 1.3 -0.5 -1.9 -1.7 -1.2 -1.3 -1.4 -1.7 -1.8 -1.8 -1.0 -1.7 -0.7 -1.3 1.2 -1.1 -1.5 -1.4 -1.4 -2.1 -0.7 -1.2 -0.7 -1.1 -1.0 1.0 0.5 -0.9 -0.8 -0.8 -0.5 -0.4 -0.6 -1.0
Average weekly fortified wine intake 0.6 0.7 3.5 -0.1 -0.2 0.4 1.2 0.2 -1.1 -1.3 0.3 -0.4 -1.0 -0.3 -0.5 -0.7 -1.9 0.7 -0.4 -0.5 0.8 -0.7 -0.1 -0.7 -0.7 1.6 0.3 -0.8 -0.7 -0.3 -0.8 -1.6 -0.9 -1.0 -1.0 -0.2 -0.4 -0.7 -0.5 -1.4
Maternal smoking around birth 0.9 1.3 8.8 -0.2 -0.7 1.6 3.0 1.4 -1.9 -1.2 -1.7 -0.8 -0.3 -0.2 -0.6 -0.5 1.5 0.2 -1.6 -1.1 0.9 -0.8 -0.3 -0.9 -0.9 -0.4 0.5 -0.9 -1.4 -1.5 -1.4 1.1 1.0 -0.7 -0.9 -0.9 -1.2 -1.2 -0.9 -0.1
Fed-up feelings 1.4 2.6 6.8 -1.6 -1.8 -1.6 1.0 0.0 -0.4 -0.2 0.8 -0.3 -1.3 -2.0 -1.5 -1.2 1.5 -1.3 -1.7 -1.4 1.4 -2.2 -1.2 -1.6 -1.6 -0.6 -0.8 -1.4 -2.3 -2.4 -2.2 -0.4 -1.4 -1.5 -2.1 -2.5 -2.4 -2.3 -2.6 -1.0
Frequency of unenthusiasm / disinterest in last 2 weeks 1.9 2.5 11.1 -1.5 -0.6 0.7 1.9 0.0 -0.6 0.4 -0.2 0.2 -1.3 -1.7 -1.2 -1.0 1.3 0.5 -2.3 -1.3 1.2 -1.9 0.0 -1.1 -1.1 -0.2 0.3 -1.0 -2.9 -2.3 -2.7 -1.0 -1.1 -1.7 -2.7 -2.0 -1.9 -3.3 -2.5 -1.7
Relative age voice broke 1.2 1.8 6.5 0.8 2.4 0.8 -0.7 -0.4 1.9 1.2 0.3 2.3 1.6 0.8 1.5 1.8 1.6 2.5 0.6 1.6 -1.3 0.7 2.5 1.6 1.6 1.6 1.1 1.8 -0.2 0.6 0.3 -1.4 -0.7 0.8 0.3 0.3 0.0 -1.0 -0.0 1.3
Taking other prescription medications 3.0 4.6 9.9 2.4 2.7 -0.5 -0.2 -0.3 1.8 0.9 1.1 2.8 2.7 1.9 2.6 2.8 3.1 0.9 2.4 2.9 -3.0 2.3 1.9 3.0 3.0 1.2 -0.9 2.5 2.7 2.5 2.6 -1.2 -0.9 2.2 2.5 1.2 1.8 1.4 1.8 2.1
Age when periods started (menarche) 2.9 6.9 18.1 -4.2 -2.9 1.6 2.3 0.0 -2.2 -0.5 -1.0 -2.1 -3.3 -3.7 -3.9 -3.6 -2.2 -1.2 -3.0 -3.2 2.7 -3.1 -1.9 -2.8 -2.8 -3.3 -0.8 -2.5 -2.6 -3.1 -2.9 0.3 -0.4 -3.3 -2.9 -2.7 -2.0 -2.3 -2.7 -3.3
Bilateral oophorectomy (both ovaries removed) 1.0 1.1 3.6 -1.1 -0.8 0.2 0.3 -1.4 0.4 1.4 -0.0 -0.1 -1.1 -1.0 -0.8 -1.0 -0.7 -0.1 -0.9 -0.8 0.9 -1.2 -0.3 -0.9 -0.9 -1.5 -0.6 -1.0 -1.3 -1.5 -1.1 -0.3 -1.0 -1.5 -1.0 -1.9 -1.9 -1.3 -1.8 -1.0
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.2 0.6 -0.0 -0.4 -0.5 0.2 0.6 -0.6 -0.0 0.3 -0.3 0.0 -0.5 0.0 -0.1 0.8 -0.1 -0.6 -0.4 0.4 -0.5 -0.2 -0.4 -0.4 -0.1 -0.1 -0.4 -0.5 -0.4 -0.5 0.6 0.4 0.6 -0.5 -0.1 -0.1 -0.5 -0.2 0.7
Tinnitus: Yes, but not now, but have in the past 0.3 0.3 2.0 0.4 -0.7 0.0 1.4 0.3 -1.1 -1.2 -0.9 -0.6 -0.5 -0.0 -0.6 -0.8 0.1 -0.3 -0.3 -0.6 0.6 -0.6 -0.6 -0.7 -0.7 0.2 0.2 -0.9 -0.2 -0.3 -0.4 0.3 0.3 -0.3 -0.4 0.0 -0.1 0.0 -0.0 -0.5
Qualifications: CSEs or equivalent 0.5 0.7 2.5 -0.6 -0.5 1.0 0.9 1.6 -1.3 -1.5 -0.6 -1.1 -0.7 -0.4 -0.6 -0.9 -0.4 0.1 -1.2 -0.9 1.1 -0.5 -0.3 -1.0 -1.0 0.3 0.9 -1.0 -1.0 -0.8 -0.9 0.8 1.0 -0.3 -0.8 -0.0 0.0 -0.5 -0.3 -0.3
Serious illness, injury or assault to yourself 0.5 0.6 1.9 -0.6 -0.6 0.5 1.2 0.2 -1.4 -1.4 -0.6 -0.9 -0.7 -0.7 -0.8 -0.7 -0.3 0.3 -1.2 -1.1 1.0 -0.6 -0.6 -0.9 -0.9 0.4 0.7 -1.0 -0.9 -0.7 -1.1 0.4 0.5 -0.2 -1.1 0.1 -0.2 -0.7 -0.2 -0.5
High blood pressure 6.0 16.8 30.8 5.2 5.0 -0.3 -1.3 1.3 3.1 -0.2 1.9 3.6 5.3 5.2 5.2 5.0 1.5 2.4 5.0 5.3 -5.0 5.5 3.9 5.3 5.3 3.9 0.6 4.9 4.8 5.0 5.4 -0.6 0.2 4.3 5.5 3.5 2.6 4.3 3.9 4.9
Hayfever, allergic rhinitis or eczema 8.7 18.9 37.7 4.8 5.8 -1.4 -3.4 -0.4 4.2 2.5 3.0 6.1 5.4 4.6 5.7 5.5 3.5 3.5 4.4 5.5 -5.6 3.9 5.2 5.9 5.9 4.7 0.2 5.1 4.0 5.2 4.1 -4.5 -2.4 4.8 3.6 3.2 3.7 1.2 3.2 4.4
Multivitamins +/- minerals 0.6 0.7 2.3 -1.2 -1.0 0.3 0.6 -1.0 -0.6 0.8 -0.3 -0.6 -1.2 -1.1 -1.3 -0.9 1.2 -0.8 -1.0 -1.0 0.9 -0.5 -0.8 -0.9 -0.9 -1.5 -0.4 -0.9 -0.7 -0.9 -0.8 0.6 0.3 -0.7 -0.7 -0.6 -0.5 -0.8 -0.5 -0.9
Stomach or abdominal pain in last month 2.9 3.6 8.8 -2.3 -2.1 1.0 1.6 -0.9 -1.7 0.5 -1.2 -2.0 -2.1 -2.0 -2.5 -2.4 -0.8 -0.7 -2.4 -2.4 3.0 -2.3 -1.6 -2.9 -2.9 -1.7 0.0 -2.9 -2.0 -2.3 -2.4 1.0 0.1 -1.6 -2.2 -1.5 -0.9 -1.5 -1.5 -1.7
Supplements: Glucosamine 0.2 0.3 1.1 0.1 -0.6 0.3 -0.4 -0.9 -0.5 0.1 -0.4 -0.8 -0.4 -0.2 -0.2 -0.4 -0.4 0.0 -0.2 -0.4 0.7 -0.4 -0.5 -0.7 -0.7 -0.9 -0.1 -1.0 0.4 0.1 0.0 0.6 0.6 0.2 0.1 0.4 0.8 0.7 0.5 -0.2
Diverticular disease/diverticulitis (self-reported) 0.9 1.1 4.7 -1.1 -0.4 1.5 1.1 0.4 -0.7 0.2 -1.9 -1.6 -0.2 -0.6 -0.8 -0.7 -0.4 0.6 -1.3 -1.3 1.6 0.3 -0.1 -1.2 -1.2 0.0 1.8 -1.2 -0.9 -0.7 -0.9 2.0 2.2 0.2 -0.6 0.7 -0.3 -0.1 0.3 0.3
Medication: Atenolol 2.4 3.0 7.7 1.8 1.7 -0.2 -0.5 -1.2 1.6 0.8 1.0 1.2 2.2 1.2 1.6 1.8 0.7 -0.0 2.5 2.1 -2.2 2.6 0.7 2.2 2.2 1.1 -0.2 2.1 2.2 2.1 2.6 0.7 0.8 2.0 2.8 1.5 1.2 2.1 1.9 2.2
Medication: Levothyroxine sodium 1.1 1.9 4.3 -1.8 -1.3 0.1 -0.4 -1.8 -0.2 0.4 1.3 -0.5 -2.0 -1.9 -1.1 -1.5 -2.0 -1.0 -1.2 -1.3 0.9 -1.6 -1.1 -1.1 -1.1 -1.7 -0.9 -0.8 -1.4 -1.6 -1.5 -0.6 -0.8 -2.1 -1.4 -1.8 -1.5 -1.3 -1.7 -1.8
Sitting height 7.7 54.3 110.2 -8.5 -8.7 1.6 3.4 2.2 -6.7 -4.0 -6.5 -8.7 -9.4 -8.4 -9.5 -9.3 -5.3 -1.8 -9.2 -9.8 10.0 -8.9 -5.8 -9.9 -9.9 -3.2 1.9 -10.5 -8.3 -8.5 -8.9 2.2 0.9 -8.5 -8.7 -5.2 -6.3 -5.0 -6.4 -8.7
Chronic bronchitis/emphysema (father) 1.9 2.2 4.1 0.7 1.3 -0.5 -1.3 -1.9 2.0 1.5 0.7 1.2 1.9 0.7 1.5 1.6 0.7 0.0 1.9 1.8 -1.8 1.5 0.9 1.8 1.8 -0.6 -0.3 2.0 1.9 1.8 1.8 0.2 0.3 2.0 1.9 1.2 1.6 1.5 1.7 2.0
High blood pressure (mother) 2.1 2.9 6.9 1.5 2.1 -0.3 -1.4 -1.0 2.6 2.1 1.5 1.5 2.1 1.4 2.4 2.5 0.9 1.4 1.8 1.9 -1.7 2.4 1.9 2.0 2.0 1.8 0.7 2.1 1.4 1.7 1.8 0.1 0.3 1.7 1.9 1.3 1.3 1.1 1.2 2.1
Body mass index (BMI) 0.4 1.7 5.2 2.1 1.1 -0.1 1.2 0.1 0.4 -0.2 0.1 0.4 1.6 1.6 1.2 1.3 -0.1 0.6 1.9 1.4 -1.1 2.0 1.1 1.2 1.2 2.2 0.9 0.7 1.4 1.6 1.9 0.4 0.6 1.3 2.0 1.4 0.4 2.3 1.2 1.8
Impedance of leg (left) 1.6 7.8 16.9 2.8 3.5 0.2 -2.5 0.1 2.3 0.7 1.5 3.3 3.5 3.3 4.0 3.8 0.5 1.6 3.0 3.6 -3.8 2.8 2.7 3.8 3.8 0.5 -0.3 4.1 3.2 3.3 3.0 -0.9 0.0 3.6 3.1 2.3 3.1 1.5 3.0 3.0
Leg predicted mass (left) 8.2 43.4 89.5 -7.2 -7.6 2.1 5.6 2.5 -6.4 -3.9 -6.0 -7.8 -8.1 -7.5 -9.1 -8.6 -3.8 -1.4 -7.9 -8.6 8.9 -7.4 -5.1 -8.7 -8.7 -1.4 2.2 -9.5 -7.6 -7.6 -7.5 2.2 0.8 -7.9 -7.5 -4.7 -6.3 -3.9 -6.1 -7.2
Trunk fat mass 1.1 4.7 10.6 -2.0 -2.5 1.2 3.2 1.1 -2.5 -1.9 -2.6 -3.0 -2.5 -2.4 -3.1 -2.6 -1.9 -0.1 -2.0 -2.7 2.8 -2.0 -1.4 -2.7 -2.7 0.4 1.3 -3.3 -2.2 -2.3 -1.9 1.3 0.7 -2.6 -1.8 -1.3 -2.5 -0.2 -1.8 -2.0
Waist circumference 0.6 2.2 6.3 -1.0 -1.9 0.4 2.5 1.2 -2.0 -1.9 -1.8 -2.3 -1.6 -1.3 -2.1 -1.7 -1.1 -0.7 -1.3 -1.9 1.9 -1.2 -1.5 -2.0 -2.0 0.7 0.7 -2.5 -1.0 -1.2 -1.0 1.2 0.8 -1.3 -1.0 -0.4 -1.3 0.6 -0.7 -1.1
Number of incorrect matches in round 0.4 0.6 4.3 -1.4 -0.7 0.4 -0.0 -1.7 0.2 1.0 -0.2 -0.5 -0.4 -1.5 -1.0 -0.9 0.1 -0.7 -0.7 -0.6 0.5 -0.4 -0.7 -0.6 -0.6 -2.1 -0.4 -0.2 -0.4 -0.6 -0.6 0.8 0.5 -0.4 -0.5 -0.3 0.6 -0.4 -0.3 -0.3
Past tobacco smoking 0.6 1.2 2.8 -1.3 -0.7 1.0 1.1 -1.4 -0.3 1.5 -0.5 -0.6 -0.9 -1.0 -1.3 -1.0 -1.7 0.2 -1.0 -0.9 1.2 -1.5 0.1 -1.1 -1.1 -1.3 0.4 -1.1 -1.3 -1.2 -1.5 -0.5 -0.4 -0.6 -1.3 -1.0 -1.5 -1.6 -1.0 -0.7
Alcohol usually taken with meals 0.1 0.2 1.2 0.2 0.2 -0.5 -0.4 -1.1 0.8 0.5 0.2 -0.0 0.1 -0.0 0.1 0.4 -0.4 0.1 0.8 0.3 -0.2 0.8 -0.0 0.3 0.3 0.3 0.2 0.2 0.5 0.4 0.8 0.1 -0.1 -0.2 0.7 0.2 -0.6 0.9 0.1 0.1
Nervous feelings 0.3 0.6 3.6 0.4 0.9 -0.5 -0.0 -0.8 1.1 1.9 0.9 1.3 1.0 0.3 0.9 1.1 0.7 0.7 0.0 0.5 -0.5 0.4 0.9 0.5 0.5 1.4 0.5 0.5 -0.3 0.3 -0.1 -0.7 -0.3 1.0 -0.1 0.3 -0.1 -0.7 0.2 1.0
Frequency of tenseness / restlessness in last 2 weeks 3.5 5.4 11.5 -2.7 -2.8 0.1 1.7 0.9 -2.4 -0.9 -2.1 -2.5 -2.4 -3.1 -2.9 -2.9 -0.1 -0.8 -3.3 -3.1 3.2 -2.9 -2.1 -3.2 -3.2 -0.8 0.4 -3.4 -2.8 -2.8 -3.2 0.9 0.4 -1.6 -3.2 -1.4 -1.2 -2.0 -1.8 -2.1
Hearing difficulty/problems with background noise 0.8 1.3 6.2 1.0 1.3 -1.4 -1.5 -0.4 1.5 0.7 1.4 1.4 1.1 0.8 1.2 1.2 -0.9 0.8 1.1 1.4 -1.2 0.6 1.1 1.2 1.2 2.0 -0.1 1.0 0.7 1.2 0.8 -2.5 -1.8 0.9 0.5 0.4 0.6 0.0 0.2 0.8
Hair/balding pattern: Pattern 2 2.7 3.5 10.0 -2.0 -1.4 1.1 2.0 0.1 -2.5 -0.1 -1.4 -1.5 -2.0 -1.6 -2.2 -2.4 0.2 0.0 -3.2 -2.6 2.7 -1.7 -1.1 -2.4 -2.4 -0.5 0.8 -2.4 -2.6 -2.0 -3.0 0.1 0.6 -0.9 -3.1 -0.4 -0.5 -2.8 -1.1 -1.8
Had menopause 0.7 0.8 4.0 0.4 0.4 1.3 1.8 1.8 -1.2 -1.4 -2.0 -0.7 0.5 -0.1 -0.1 -0.2 0.3 0.8 -0.4 -0.3 0.5 0.9 0.1 -0.2 -0.2 0.4 1.5 -0.2 -0.0 0.1 0.0 1.6 1.9 0.6 0.3 1.0 0.0 0.5 0.8 1.0
Had other major operations 0.8 1.0 3.9 -0.3 -0.3 0.3 1.0 -1.0 0.2 0.8 0.2 0.5 -1.0 -0.7 -0.4 -0.4 -1.2 0.4 -0.5 -0.3 0.4 -1.4 0.3 -0.4 -0.4 -0.2 -0.5 -0.6 -1.0 -1.0 -1.1 -1.9 -2.0 -1.6 -1.2 -1.8 -1.3 -1.4 -1.7 -1.5
Forced vital capacity (FVC) 1.0 3.7 8.6 -1.9 -1.2 0.2 -0.7 1.0 -0.2 -0.7 -2.0 -1.7 -2.2 -1.9 -1.7 -1.6 -2.9 1.5 -2.2 -1.9 2.6 -2.6 -0.1 -2.3 -2.3 1.7 1.9 -2.6 -2.7 -2.1 -2.3 -0.9 -0.7 -2.6 -2.4 -1.4 -2.7 -1.7 -2.2 -2.2
Heel bone mineral density (BMD) T-score, automated (right) 0.1 0.2 1.4 0.3 -0.3 -0.7 0.2 -0.6 -0.4 0.5 0.8 0.4 0.0 -0.4 0.4 0.2 0.3 -0.7 -0.0 0.1 -0.2 -0.3 -0.2 0.0 0.0 -0.8 -1.2 -0.1 -0.0 -0.2 -0.2 -0.0 -0.4 0.6 -0.2 -0.6 0.3 -0.7 -0.2 0.4
Ever unenthusiastic/disinterested for a whole week 0.3 0.4 1.8 0.7 -0.1 -1.1 -1.3 -0.6 0.6 -0.0 1.3 0.7 0.2 0.3 0.6 0.7 0.2 -0.5 0.2 0.3 -0.4 -0.2 -0.3 0.2 0.2 0.8 -0.9 0.2 -0.0 0.0 -0.0 -1.0 -1.2 -0.1 -0.2 -0.6 -0.1 -0.5 -0.5 -0.3
Qualifications: None of the above 0.7 1.6 5.4 -1.4 -0.5 -1.2 0.1 -1.8 1.5 2.3 1.5 1.1 -0.8 -1.8 -0.8 -0.5 1.8 -1.5 0.2 -0.2 -0.2 -0.6 -0.7 -0.1 -0.1 -2.0 -2.0 0.4 -0.9 -1.2 -0.8 -0.6 -1.5 -1.4 -0.7 -2.1 -0.9 -1.7 -1.8 -1.1
Financial difficulties in last 2 years 1.2 1.6 3.8 -1.2 -1.9 -1.1 0.6 -0.5 -1.1 -0.7 -0.5 -1.4 -1.4 -1.6 -1.6 -1.6 -1.3 -1.3 -1.4 -1.5 1.8 -1.5 -1.8 -2.0 -2.0 -0.2 -0.7 -1.9 -1.0 -1.2 -1.3 0.2 -0.5 -0.7 -1.5 -0.8 -0.4 -0.6 -1.0 -0.9
Mouth/teeth dental problems 0.7 1.1 4.3 1.6 0.6 -0.5 -1.9 1.0 -0.1 -1.3 -1.2 -0.4 0.3 1.5 0.8 0.6 -1.3 0.9 0.8 0.6 -0.5 0.8 0.2 0.5 0.5 2.1 0.9 0.2 1.2 1.6 1.2 -0.5 0.2 0.7 0.8 1.8 1.3 1.4 1.5 0.2
Heart attack 2.3 3.0 6.8 1.9 2.1 1.4 0.7 0.4 0.4 0.9 -1.3 0.6 2.3 1.7 1.2 1.6 1.1 1.1 1.7 1.8 -1.3 2.6 1.5 1.6 1.6 1.1 1.2 1.5 2.0 2.1 2.0 1.0 1.8 2.5 2.2 2.5 1.8 1.9 2.6 2.5
Allergy 16.8 38.6 71.2 -7.0 -8.4 1.1 4.0 -0.7 -5.2 -2.6 -2.5 -7.5 -8.2 -7.0 -7.7 -8.0 -6.3 -4.9 -6.3 -7.8 7.7 -6.7 -7.2 -8.2 -8.2 -6.7 -1.5 -7.3 -5.9 -7.6 -6.3 4.3 1.2 -7.5 -5.8 -5.8 -5.3 -2.9 -5.7 -7.2
Pain all over the body in last month 2.1 2.3 5.7 -1.6 -1.4 -2.1 -0.3 -1.9 0.9 1.2 0.3 0.1 -1.8 -1.8 -1.1 -1.0 1.7 -1.9 -0.6 -0.8 0.6 -1.5 -1.8 -1.0 -1.0 -1.7 -1.9 -0.9 -1.4 -1.8 -1.3 -0.4 -1.7 -1.9 -1.4 -2.4 -1.9 -1.8 -2.2 -1.9
Diabetes (self-reported) 0.6 0.9 5.2 0.1 0.3 0.2 1.2 1.4 0.0 -0.8 -1.2 -0.6 0.6 -0.0 0.2 0.4 -0.1 -0.2 1.1 0.6 -0.6 1.6 -0.3 0.5 0.5 -0.5 0.1 0.4 1.6 1.0 1.5 1.6 1.4 0.6 1.7 1.1 0.7 2.3 1.5 0.8
Hayfever/allergic rhinitis (self-reported) 2.5 3.3 6.7 2.1 2.6 -0.3 -0.7 0.9 1.1 0.3 1.4 2.5 2.4 2.1 2.1 2.2 0.8 1.8 1.5 2.3 -2.3 1.5 2.4 2.5 2.5 2.2 0.4 2.1 1.7 2.4 1.7 -2.2 -0.9 2.3 1.3 1.7 1.7 0.6 1.6 1.8
Medication: Ramipril 2.1 2.7 5.7 1.9 2.0 1.1 0.3 -0.1 0.9 0.6 -0.2 1.4 2.2 2.0 1.8 1.7 -0.4 0.5 2.4 2.3 -2.1 2.2 1.7 2.2 2.2 0.2 -0.4 1.9 2.2 1.9 2.1 -0.1 0.2 1.9 2.3 1.1 1.4 1.7 1.7 1.9
Medication: Simvastatin 0.2 0.3 2.3 -0.3 0.1 -0.6 0.7 0.1 0.9 1.2 0.5 0.1 0.2 -0.8 -0.1 0.1 1.5 0.4 -0.4 -0.1 0.0 -0.5 0.1 0.0 0.0 0.3 0.5 0.2 -0.9 -0.6 -0.7 -0.3 -0.2 -0.1 -0.6 -0.4 -1.2 -0.9 -0.6 0.4
Fluid intelligence score 0.3 0.7 7.0 0.9 0.3 -1.6 -0.3 -0.0 0.3 -0.2 1.0 1.3 0.6 0.2 0.8 0.9 2.6 -0.4 0.5 0.6 -0.9 -0.5 0.0 0.7 0.7 0.3 -1.1 0.5 -0.3 -0.1 -0.0 -1.2 -1.5 0.3 -0.3 -0.8 -0.3 -0.9 -0.9 0.4
Illnesses of siblings 2.8 3.9 8.9 -2.3 -2.3 0.5 1.2 0.6 -0.9 -1.2 -2.1 -1.8 -2.3 -2.5 -2.3 -2.2 -1.3 -0.0 -2.1 -2.3 2.3 -2.4 -1.3 -2.3 -2.3 -1.0 0.5 -2.2 -2.6 -2.7 -2.1 1.0 -0.0 -3.0 -2.0 -2.3 -2.8 -1.3 -2.6 -2.2
Neuroticism score 1.2 2.5 6.8 -2.1 -1.4 -1.6 0.4 -1.5 0.3 1.5 1.3 -0.1 -1.3 -2.6 -1.5 -0.8 1.2 -0.6 -2.2 -1.6 1.6 -2.0 -0.7 -1.6 -1.6 0.1 -0.2 -1.5 -2.4 -2.1 -2.3 -0.6 -1.3 -1.1 -2.3 -1.9 -1.7 -2.5 -2.3 -1.0
Weight 3.9 19.4 43.8 -4.5 -5.2 1.6 4.7 2.2 -4.7 -3.1 -4.7 -5.7 -5.2 -4.8 -6.0 -5.6 -3.0 -0.8 -5.1 -5.8 6.0 -4.6 -3.3 -5.9 -5.9 -0.4 2.1 -6.6 -4.8 -4.9 -4.7 2.3 1.4 -5.0 -4.5 -2.7 -4.3 -1.7 -3.7 -4.3
Impedance of arm (right) 0.1 0.6 4.4 -1.2 -0.8 0.3 -0.5 0.1 -0.1 -1.3 0.2 -0.2 -0.8 -0.9 -0.6 -0.4 -1.2 -0.7 -0.4 -0.4 0.1 -1.1 -1.0 -0.3 -0.3 -2.1 -1.3 0.1 -0.1 -0.8 -0.5 0.1 -0.6 -0.8 -0.4 -1.3 -0.1 -0.4 -0.7 -1.0
Arm fat percentage (right) 0.4 1.5 6.1 1.9 0.8 -0.5 0.7 -0.2 0.8 -0.4 0.6 0.3 1.4 1.4 1.1 1.5 -0.4 0.3 2.2 1.4 -1.2 1.7 0.7 1.2 1.2 1.8 0.2 0.7 1.6 1.4 2.1 0.4 0.1 0.9 2.1 0.8 0.3 2.5 0.9 1.5
Trunk fat-free mass 8.2 47.2 102.2 -7.4 -8.0 1.8 4.9 3.0 -6.7 -4.0 -6.7 -8.1 -8.5 -7.7 -9.2 -8.8 -3.5 -1.5 -8.6 -9.2 9.4 -7.9 -5.3 -9.3 -9.3 -1.5 2.4 -10.1 -8.0 -7.9 -8.0 2.3 1.1 -7.9 -8.0 -4.6 -6.4 -4.2 -6.1 -7.4
Hip circumference 0.3 1.4 4.5 -0.6 -1.4 0.5 1.8 0.6 -1.2 -1.1 -2.0 -1.9 -1.0 -1.2 -1.8 -1.3 -1.6 0.3 -0.7 -1.5 1.7 -0.8 -0.5 -1.6 -1.6 1.2 1.4 -2.1 -0.8 -0.7 -0.4 0.9 0.7 -1.4 -0.5 -0.1 -1.1 1.0 -0.6 -0.7
Time employed in main current job 0.3 0.4 1.9 -0.1 -0.7 -0.9 -0.5 -1.2 1.1 0.6 1.1 0.2 -0.4 -0.2 0.1 0.1 0.4 -1.1 0.4 0.1 -0.1 -0.2 -0.9 -0.2 -0.2 -1.1 -1.4 -0.1 0.2 -0.2 0.1 -0.1 -0.7 -0.2 0.1 -0.8 0.1 0.0 -0.5 -0.5
Alcohol intake versus 10 years previously 0.7 1.1 4.9 0.2 1.5 -0.3 -1.5 -1.4 1.9 1.9 0.4 1.2 0.1 0.2 0.8 0.9 -0.9 2.2 0.3 0.5 -0.4 0.7 2.0 0.8 0.8 2.1 1.8 0.9 -0.5 0.5 0.1 -1.3 -0.4 -0.1 -0.2 0.7 0.3 -0.4 -0.0 -0.0
Father’s age at death 7.3 9.8 19.7 -4.4 -4.1 0.7 1.6 1.3 -3.6 -2.0 -2.4 -4.3 -3.8 -3.7 -4.1 -4.1 -1.7 -2.1 -4.0 -4.4 3.9 -2.7 -3.7 -4.0 -4.0 -3.1 -0.0 -3.9 -2.8 -3.4 -3.2 2.8 1.8 -3.0 -2.9 -1.8 -1.9 -1.3 -1.9 -3.2
Worrier / anxious feelings 0.8 1.6 4.8 -1.7 -1.7 -1.4 0.5 -1.1 -0.2 -0.4 0.9 -0.4 -1.3 -2.2 -1.7 -1.2 0.9 -1.8 -1.3 -1.3 1.1 -1.3 -1.7 -1.4 -1.4 0.3 -1.1 -1.1 -1.4 -1.4 -1.3 -0.1 -0.9 -1.0 -1.4 -1.4 -0.7 -1.4 -1.6 -1.1
Frequency of tiredness / lethargy in last 2 weeks 3.0 4.9 11.7 -2.2 -2.0 -2.1 -0.0 -2.2 0.4 1.4 0.3 -0.2 -2.2 -2.9 -1.9 -1.5 1.0 -1.1 -2.4 -2.0 1.9 -3.3 -1.7 -2.1 -2.1 0.3 -0.8 -2.2 -3.2 -2.9 -3.0 -1.7 -2.3 -2.5 -3.4 -2.9 -2.5 -3.4 -3.4 -2.2
Falls in the last year 0.3 0.4 3.3 -0.7 -0.0 0.7 1.8 -0.1 0.3 0.7 -0.0 0.4 -0.2 -0.5 -0.3 0.1 -0.1 0.3 -0.3 -0.1 0.2 -0.2 0.2 -0.1 -0.1 -0.3 -0.3 -0.4 -0.5 -0.8 -0.4 -0.2 -0.7 -0.9 -0.1 -1.4 -1.8 -0.4 -1.0 -0.1
Hair/balding pattern: Pattern 3 3.0 4.5 13.1 2.3 1.4 -1.8 -2.0 -0.4 2.7 0.1 2.8 2.1 1.6 2.2 2.6 2.7 0.3 -0.2 3.6 3.0 -2.7 2.0 1.0 2.4 2.4 0.6 -1.8 2.3 3.1 2.4 3.4 -0.7 -1.5 1.0 3.3 0.4 1.4 2.8 1.2 1.3
Number of live births 1.5 2.2 12.3 -1.0 -1.8 1.1 1.7 1.0 -2.0 -1.3 -0.9 -2.5 -0.7 -0.7 -1.5 -1.4 0.0 -2.6 -0.8 -1.5 1.3 0.5 -2.8 -1.6 -1.6 -2.2 -0.8 -1.3 0.3 -0.7 -0.2 3.5 2.6 0.3 0.4 0.2 0.3 1.2 0.8 0.1
Forced expiratory volume in 1-second (FEV1) 3.3 11.3 24.7 -3.7 -3.9 -1.0 0.1 0.0 -0.7 -0.4 -1.5 -3.0 -4.7 -3.9 -3.7 -3.5 -3.6 -0.9 -3.2 -3.7 4.2 -4.7 -2.7 -4.3 -4.3 -0.5 -0.2 -4.5 -4.0 -4.2 -3.8 -0.5 -1.8 -5.0 -3.9 -3.9 -4.2 -2.6 -4.4 -4.5
Pulse rate 0.1 0.2 0.8 -0.1 -0.6 0.3 0.7 -0.4 -0.7 -0.6 0.4 -0.6 -0.3 -0.4 -0.2 -0.2 -0.9 -0.7 -0.0 -0.3 0.2 -0.2 -0.7 -0.3 -0.3 -0.2 -0.3 -0.1 0.2 -0.0 0.2 0.5 0.3 -0.5 0.1 -0.0 0.5 0.5 0.1 -0.5
Happiness 2.1 2.6 6.6 -2.4 -1.5 -0.6 0.7 0.4 -0.6 0.3 -1.1 -1.0 -1.3 -2.3 -2.4 -2.0 0.1 -0.1 -2.4 -1.9 1.9 -2.2 -1.1 -1.9 -1.9 0.2 0.6 -2.0 -2.4 -1.9 -2.4 -0.5 -0.7 -0.9 -2.6 -1.2 -1.6 -2.2 -1.7 -1.1
Noisy workplace 2.9 3.6 11.1 2.7 1.9 1.1 -0.2 1.6 -0.6 -1.9 -0.4 0.1 2.4 2.7 1.8 1.5 -0.4 1.9 1.0 1.4 -1.1 2.1 1.6 1.4 1.4 3.3 2.5 1.4 1.6 2.4 1.7 0.3 1.6 2.6 1.6 3.3 2.2 2.1 2.7 2.4
Qualifications: A levels/AS levels or equivalent 0.4 0.9 8.7 1.5 0.5 -0.8 -1.2 1.0 0.1 -1.1 -1.0 -0.2 0.7 1.5 1.1 0.8 -1.0 1.3 0.5 0.6 -0.2 0.4 0.8 0.3 0.3 2.9 1.6 -0.1 0.4 0.9 0.7 -0.3 0.0 0.8 0.6 1.1 0.2 1.2 0.7 1.0
Serious illness, injury or assault of a close relative in last 2 years 2.1 2.4 7.3 -1.7 -2.3 -2.5 -1.2 0.7 -1.5 -2.0 -0.6 -1.9 -1.6 -1.8 -1.9 -1.9 1.1 -2.1 -1.7 -2.0 1.8 -1.7 -2.7 -2.1 -2.1 -0.0 -0.6 -2.2 -1.1 -1.1 -1.3 0.6 0.1 -0.5 -1.7 -0.3 0.4 -0.5 -0.7 -0.9
Mouth/teeth dental problems: Dentures 1.1 1.9 12.7 -0.8 0.0 2.7 3.6 1.9 -1.8 -0.5 -1.1 -0.7 -0.1 -0.5 -0.5 -0.4 2.8 0.2 -1.1 -0.8 0.8 0.6 0.5 -0.5 -0.5 -2.2 0.8 -0.0 -1.2 -1.6 -1.0 3.0 2.6 -0.5 -0.2 -0.6 -0.9 -0.7 -0.4 0.3
Asthma 25.7 50.6 100.2 8.2 9.9 -0.8 -3.6 0.3 5.4 3.4 3.0 8.8 9.5 8.1 8.7 9.2 10.0 5.3 6.9 9.0 -8.9 7.9 8.1 9.5 9.5 7.0 1.2 8.7 6.6 8.3 7.0 -4.2 -1.0 8.5 6.7 6.2 6.0 2.8 6.4 8.0
Medication: Ibuprofen (e.g. Nurofen) 0.3 0.4 1.6 -0.4 -0.1 0.3 1.2 -0.1 -0.8 -0.1 -1.0 -0.5 -0.3 -0.3 -0.6 -0.6 -1.3 0.7 -1.0 -0.5 0.8 -0.9 -0.1 -0.6 -0.6 0.3 0.6 -0.7 -0.8 -0.6 -1.0 -0.6 -0.2 -0.1 -1.0 -0.2 -0.7 -0.9 -0.4 -0.3
Medication: Cholesterol lowering 1.5 2.3 5.4 1.8 1.8 -0.6 -0.4 -0.3 1.0 1.6 0.7 1.2 1.7 1.2 1.4 1.4 0.7 0.4 1.8 1.9 -1.7 1.5 0.9 1.7 1.7 1.1 0.2 1.7 1.9 2.3 1.8 -0.9 0.0 2.3 1.5 2.2 2.3 1.3 2.1 1.8
Depression (self-reported) 0.3 0.4 3.4 -0.3 -0.2 -0.8 -1.1 -1.0 1.0 1.9 0.3 -0.1 -0.8 -0.6 0.3 0.6 -0.7 -0.2 0.1 -0.1 0.6 -0.1 -0.2 -0.6 -0.6 0.0 -0.7 -1.0 0.3 0.1 -0.2 -0.5 -0.7 -0.2 -0.3 -0.1 0.9 0.0 0.1 -1.0
Medication: Lansoprazole 0.4 0.5 2.9 -0.3 -0.0 1.1 1.7 0.5 -1.4 -1.0 -0.7 -0.5 0.1 -0.1 -0.2 -0.6 0.1 0.6 -1.1 -0.5 0.7 -0.3 0.0 -0.6 -0.6 0.1 0.9 -0.7 -0.3 -0.1 -0.7 0.4 0.8 0.5 -0.6 0.7 0.9 -0.5 0.6 -0.1
Prospective memory result 0.7 0.8 2.1 1.3 0.9 -0.4 -1.0 -1.2 0.7 0.5 1.4 0.7 1.2 1.0 1.4 1.2 -0.1 0.1 0.8 0.8 -1.1 1.1 0.3 1.0 1.0 1.1 0.0 1.1 0.7 1.0 0.8 -0.2 0.3 1.4 0.8 1.0 0.8 0.5 0.9 1.1
Lung cancer (father) 1.9 2.2 4.6 -1.6 -2.1 0.3 1.1 0.0 -2.0 -1.0 -1.2 -1.7 -1.5 -1.5 -2.0 -2.1 0.5 -1.7 -1.6 -1.9 1.8 -1.8 -2.1 -2.0 -2.0 -1.8 -0.5 -2.1 -1.0 -1.4 -1.5 1.4 0.8 -0.8 -1.5 -0.7 0.3 -0.5 -0.7 -1.1
Illnesses of mother 2.4 2.9 7.0 -1.7 -2.6 -0.4 0.7 0.3 -1.7 -0.8 -1.5 -2.4 -2.4 -1.2 -2.6 -2.3 -1.4 -1.8 -1.2 -2.0 1.9 -2.1 -2.6 -2.3 -2.3 -1.7 -0.4 -2.3 -1.1 -1.6 -1.3 1.0 0.3 -2.0 -1.4 -1.1 -1.4 -0.0 -1.1 -2.2
Forced expiratory volume in 1-second (FEV1), Best measure 3.7 11.7 29.1 -3.6 -3.7 -1.0 0.0 -0.2 -0.2 -0.4 -1.0 -2.5 -4.8 -4.1 -3.5 -3.4 -4.1 -0.5 -3.0 -3.5 4.0 -5.0 -2.1 -4.1 -4.1 -0.6 -0.3 -4.3 -4.2 -4.3 -3.9 -1.3 -2.7 -5.4 -4.0 -4.4 -4.6 -2.9 -4.9 -4.7
Pulse wave Arterial Stiffness index 0.8 0.9 5.9 -0.5 -1.2 0.1 1.4 0.2 -2.0 -2.4 0.4 -0.9 -1.2 -1.1 -1.1 -1.2 -1.6 -1.4 -0.7 -0.8 0.7 -0.9 -1.3 -0.9 -0.9 -0.4 -0.9 -0.9 0.1 -0.3 -0.5 0.0 -0.2 -0.6 -0.6 -0.3 0.4 -0.1 -0.0 -1.4
Impedance of arm (left) 0.2 0.9 5.0 -1.6 -0.7 0.7 -0.3 -0.2 -0.1 -0.6 0.4 -0.0 -1.0 -1.2 -0.8 -0.6 -1.1 -0.4 -0.7 -0.6 0.3 -1.3 -0.7 -0.4 -0.4 -2.2 -1.2 0.1 -0.6 -1.1 -1.0 -0.2 -0.8 -1.2 -0.8 -1.6 -0.4 -1.1 -1.1 -1.4
Arm fat mass (right) 0.5 2.2 7.2 -0.8 -1.7 0.7 2.7 0.9 -1.7 -1.6 -1.9 -2.4 -1.4 -1.3 -2.0 -1.6 -1.7 0.1 -1.0 -1.8 2.0 -1.1 -0.9 -1.9 -1.9 0.9 1.3 -2.6 -1.3 -1.3 -0.9 1.2 0.8 -1.6 -0.8 -0.6 -1.8 0.6 -1.0 -0.9
Trunk predicted mass 8.2 46.8 102.0 -7.4 -8.0 1.7 4.8 2.9 -6.7 -3.9 -6.7 -8.1 -8.5 -7.7 -9.2 -8.8 -3.5 -1.5 -8.5 -9.1 9.4 -7.9 -5.3 -9.2 -9.2 -1.6 2.4 -10.1 -7.9 -7.8 -7.9 2.3 1.0 -7.8 -8.0 -4.6 -6.3 -4.2 -6.0 -7.4
Standing height 14.2 140.8 255.6 -14.3 -13.6 3.8 7.5 4.7 -11.0 -6.4 -10.8 -13.2 -14.8 -14.1 -15.7 -15.2 -6.4 -2.8 -15.2 -15.6 15.6 -14.3 -9.3 -15.4 -15.5 -5.6 3.0 -16.0 -13.7 -14.0 -14.4 4.1 1.7 -13.6 -14.1 -8.8 -10.5 -8.5 -10.6 -13.4
Length of working week for main job 0.5 0.5 1.8 0.8 0.7 1.1 0.6 0.8 -0.4 -0.5 -1.1 0.1 1.1 0.8 0.4 0.4 -0.2 0.9 0.0 0.4 -0.4 0.7 0.7 0.5 0.5 0.1 1.2 0.5 0.3 0.7 0.2 0.3 1.1 1.3 0.4 1.2 0.7 0.5 1.0 1.1
Exposure to tobacco smoke at home 0.8 0.9 3.7 -0.8 -0.9 0.5 0.6 0.9 -0.3 -0.3 -0.9 -1.3 -0.8 -1.0 -0.6 -0.5 1.6 -0.2 -0.8 -1.1 1.0 -0.2 -0.5 -0.9 -0.9 -0.6 0.7 -0.6 -1.0 -1.3 -0.8 1.9 1.3 -1.1 -0.4 -0.7 -1.9 -0.1 -0.7 -0.7
Breastfed as a baby 0.7 0.8 4.1 -1.2 -1.1 0.4 0.2 0.6 -1.0 -0.9 -0.3 -1.8 -1.1 -0.2 -1.4 -1.5 -2.0 -0.4 -0.8 -1.1 1.1 -0.5 -0.9 -1.1 -1.1 -0.9 0.9 -1.0 -0.3 -0.4 -0.3 1.0 0.9 -0.6 -0.2 0.3 -0.6 0.9 0.1 -0.5
Tense / ‘highly strung’ 1.1 1.8 6.6 -1.4 -0.4 0.9 1.5 0.4 -1.1 1.0 -0.5 -0.5 -0.6 -1.1 -1.0 -0.7 0.4 1.1 -2.3 -1.7 1.8 -1.3 0.3 -1.5 -1.5 0.5 1.6 -1.3 -2.6 -1.8 -2.5 -0.2 0.2 -0.6 -2.3 -0.6 -1.5 -2.4 -1.2 -0.7
Seen doctor (GP) for nerves, anxiety, tension or depression 0.7 1.0 4.1 -0.7 -1.1 0.1 2.0 0.1 -0.5 0.5 -0.6 -1.2 -1.1 -1.0 -0.9 -0.5 -0.7 0.0 -1.0 -1.1 1.5 -1.0 -0.4 -1.4 -1.4 0.7 0.8 -1.7 -1.2 -1.2 -1.3 0.7 0.3 -1.1 -1.1 -0.6 -1.0 -0.5 -0.8 -1.1
Hair/balding pattern: Pattern 4 0.7 1.8 11.4 1.2 0.6 0.9 -0.4 0.5 1.4 0.3 0.4 -0.2 1.0 1.3 1.4 1.3 -3.4 -0.2 2.2 1.4 -1.1 1.6 0.0 1.0 1.0 -0.8 -0.6 0.9 2.2 1.2 2.2 1.0 0.5 0.2 2.6 0.2 -0.0 2.9 1.1 0.9
Birth weight of first child 2.8 5.0 10.6 -2.6 -2.5 -0.2 0.7 0.6 -2.1 -1.4 -0.9 -1.9 -3.2 -2.4 -2.7 -2.9 -2.5 -0.7 -2.6 -2.6 2.8 -3.0 -1.9 -2.8 -2.8 -1.1 -0.2 -2.8 -2.5 -2.4 -2.8 -0.7 -1.0 -2.6 -3.0 -1.9 -1.8 -2.0 -2.2 -3.1
Peak expiratory flow (PEF) 3.5 8.2 17.6 -3.0 -3.5 0.2 1.3 1.4 -1.7 -1.3 -2.0 -3.4 -3.7 -2.6 -3.4 -3.3 -2.3 -0.9 -3.0 -3.5 3.9 -3.3 -2.5 -3.9 -3.9 -1.2 0.2 -4.2 -3.2 -3.7 -3.1 1.1 -0.2 -3.9 -2.9 -3.0 -3.7 -1.7 -3.3 -3.2
Pulse wave reflection index 1.1 1.4 3.0 1.0 1.5 -0.9 -1.2 -0.8 1.4 -0.3 1.7 1.7 1.0 1.1 1.3 1.3 -0.7 0.7 1.5 1.7 -1.4 1.2 1.3 1.5 1.5 1.5 -0.2 1.4 1.1 1.4 1.3 -1.6 -1.2 0.6 1.1 0.5 0.5 0.5 0.5 0.6
Ever highly irritable/argumentative for 2 days 0.3 0.3 1.2 0.2 -0.2 0.7 0.9 -0.1 -0.7 0.2 -1.0 -0.7 -0.3 -0.4 -0.6 -0.3 -0.2 0.7 -0.5 -0.6 1.0 -0.4 0.1 -0.8 -0.8 0.9 1.1 -1.0 -0.6 -0.4 -0.6 0.5 0.5 0.1 -0.5 0.2 -0.8 0.0 0.0 -0.0
Loud music exposure frequency 0.8 0.9 3.2 0.7 1.3 -0.3 -0.6 0.6 0.9 0.3 -0.4 0.5 1.1 1.3 1.1 1.1 1.2 1.0 0.7 0.9 -0.8 1.5 0.9 0.9 0.9 1.8 0.9 0.6 0.7 1.2 1.0 -0.0 0.5 1.2 1.0 1.3 0.5 0.8 1.1 1.4
Qualifications: O levels/GCSEs or equivalent 0.8 1.3 3.8 -0.0 -1.4 -0.4 0.3 1.1 -1.3 -1.0 -1.2 -1.4 -1.5 -0.4 -0.8 -1.2 -0.7 0.3 -1.4 -1.4 1.5 -1.9 -1.0 -1.5 -1.5 1.4 1.0 -1.8 -1.3 -1.0 -1.2 -0.3 -0.2 -1.2 -1.4 -0.5 -1.3 -0.5 -1.0 -1.3
Mouth/teeth dental problems: Bleeding gums 1.5 2.0 5.4 0.6 0.7 -1.5 -2.0 -2.0 1.9 1.1 2.3 1.4 1.2 0.7 1.2 1.3 -1.0 -1.1 2.0 1.7 -1.9 0.9 0.3 1.6 1.6 -0.4 -1.6 1.7 2.1 1.5 1.8 -0.7 -0.9 1.2 1.8 0.3 1.1 1.5 1.0 1.1
Blood clot in the leg (DVT) 1.2 1.6 5.4 -1.6 -1.7 0.4 0.9 1.2 -1.9 -0.6 -1.6 -2.3 -1.2 -1.2 -2.0 -1.7 -1.1 -1.3 -0.9 -1.6 1.6 -0.8 -1.9 -1.7 -1.7 -1.3 0.1 -1.8 -0.2 -0.7 -0.8 1.3 1.0 -0.4 -0.7 0.1 -0.3 0.6 0.1 -0.7
Medication: Paracetamol 1.6 2.7 5.7 -1.3 -1.9 -0.7 1.5 1.5 -1.8 -1.4 -1.4 -1.9 -1.9 -1.3 -1.8 -1.8 -0.6 -0.1 -2.2 -1.9 2.2 -2.4 -1.4 -2.3 -2.3 0.3 0.8 -2.3 -2.2 -1.9 -2.2 0.2 -0.2 -1.4 -2.4 -1.0 -1.0 -1.4 -1.7 -1.4
Headache pain in last month 0.3 0.6 4.7 0.2 -0.0 1.0 1.1 -0.7 -0.3 0.9 0.4 -0.3 -0.1 0.4 -0.1 -0.0 -2.2 1.0 -1.0 -0.4 0.9 -1.0 0.5 -0.7 -0.7 1.2 1.1 -0.8 -0.7 -0.3 -0.9 -0.8 -0.3 -0.1 -0.8 0.1 -0.4 -0.7 -0.2 -0.1
Medication for cholesterol, blood pressure or diabetes 3.4 5.6 11.1 -2.6 -3.0 0.7 1.3 0.1 -1.9 -1.4 -0.9 -2.0 -3.0 -2.1 -2.4 -2.3 -1.7 -0.8 -2.9 -3.1 2.9 -2.7 -1.7 -3.0 -3.0 -1.4 -0.1 -2.9 -2.9 -3.3 -2.9 0.8 -0.1 -3.3 -2.7 -2.9 -3.0 -2.1 -2.9 -3.0
Glaucoma (self-reported) 1.6 1.9 4.6 1.9 1.8 1.0 1.2 1.9 0.1 -0.5 -0.6 0.2 1.7 1.9 1.2 1.3 0.8 2.1 1.1 1.3 -1.0 1.8 1.7 1.3 1.3 2.1 2.1 1.0 0.5 1.0 1.3 0.7 1.3 1.3 1.6 1.4 -0.5 1.5 1.1 2.0
Gout (self-reported) 0.8 1.1 7.8 -1.0 0.4 0.6 0.6 1.9 -0.3 -1.1 -1.5 -0.6 -0.5 -0.8 -0.9 -0.7 -0.1 2.3 -1.3 -0.7 1.1 -0.6 1.0 -0.7 -0.7 1.7 2.8 -0.4 -1.6 -0.5 -1.2 -0.6 0.3 -0.7 -1.3 0.5 -0.8 -0.8 -0.6 -0.2
Hypothyroidism/myxoedema (self-reported) 1.9 3.7 8.6 -2.3 -1.5 0.7 0.8 -1.8 -0.4 0.8 1.4 -0.4 -2.5 -2.4 -1.7 -1.9 -1.4 -0.6 -2.2 -1.9 1.6 -2.3 -1.0 -1.6 -1.6 -1.3 -0.7 -1.3 -2.7 -2.7 -2.6 -0.9 -1.2 -2.9 -2.5 -2.8 -2.3 -2.7 -2.8 -2.6
Medication: Amlodipine 3.7 5.2 11.5 1.9 3.1 0.8 -0.5 0.0 2.0 0.5 0.5 1.7 3.4 2.3 2.5 2.6 1.5 1.7 2.4 2.9 -2.5 3.2 2.4 2.8 2.8 2.1 1.3 2.8 2.5 2.7 2.8 0.3 0.9 2.8 3.1 2.4 1.0 2.4 2.6 3.3
Medication: Ventolin 100micrograms inhaler 4.5 5.8 21.8 2.5 2.6 -2.0 -2.7 -0.4 2.0 2.0 1.1 2.7 3.0 2.6 2.9 3.0 4.7 1.1 1.8 2.4 -2.7 2.4 1.9 2.8 2.8 2.8 0.1 2.2 2.3 3.0 2.2 -1.8 -0.6 3.3 1.9 2.4 2.7 0.9 2.4 2.6
Birth weight 3.1 6.8 14.6 -3.1 -3.5 0.4 1.9 0.3 -2.4 -1.7 -2.0 -2.8 -3.8 -3.5 -3.4 -3.4 -1.5 -2.3 -2.5 -3.2 3.0 -2.9 -3.0 -3.3 -3.3 -2.9 -1.0 -3.2 -2.0 -2.8 -2.5 1.3 0.3 -3.5 -2.5 -2.2 -1.2 -1.0 -2.1 -3.8
Chronic bronchitis/emphysema (mother) 2.2 2.6 5.7 2.1 2.4 0.9 -0.3 0.0 0.5 -0.0 0.5 1.9 2.2 2.0 1.8 1.8 1.1 1.4 1.0 1.9 -1.9 1.6 1.8 2.1 2.1 1.9 0.4 1.8 1.7 2.1 1.4 -1.2 -0.0 2.2 1.3 1.9 2.3 0.6 2.0 1.5
High blood pressure (siblings) 3.7 5.4 10.9 2.9 2.6 -0.6 -1.6 -0.4 0.9 0.1 2.3 2.2 2.9 2.8 3.0 2.7 0.7 0.1 2.6 2.8 -3.0 2.7 1.5 2.9 2.9 1.3 -0.7 2.8 3.0 3.1 2.6 -1.2 -0.1 3.3 2.4 2.4 3.0 1.8 2.8 2.6
Forced vital capacity (FVC), Best measure 0.9 3.4 11.1 -1.6 -0.9 0.1 -0.8 0.9 0.2 -0.6 -1.4 -1.2 -2.2 -1.9 -1.4 -1.3 -3.3 1.8 -1.9 -1.6 2.3 -2.6 0.4 -1.9 -1.9 1.5 1.8 -2.2 -2.5 -1.8 -2.1 -1.6 -1.4 -2.7 -2.2 -1.5 -2.6 -1.7 -2.3 -2.2
Body fat percentage 0.3 1.1 3.8 1.4 0.9 0.4 1.5 0.1 0.2 -0.5 0.2 0.2 1.2 1.1 0.8 1.2 -0.5 0.7 1.7 1.1 -1.0 1.4 0.9 1.1 1.1 1.6 0.6 0.7 1.1 1.1 1.6 0.5 0.5 0.7 1.7 0.8 -0.0 1.9 0.8 1.3
Leg fat percentage (right) 1.8 6.5 13.8 3.7 2.7 -0.3 0.3 0.2 1.3 -0.4 1.3 1.9 3.3 3.3 3.2 3.3 0.6 1.2 3.6 3.1 -3.0 3.4 2.2 3.0 3.0 2.9 0.6 2.6 2.9 3.1 3.4 -0.1 0.4 3.0 3.5 2.4 1.5 3.2 2.5 3.4
Arm fat-free mass (right) 6.7 34.2 75.2 -6.2 -6.7 1.9 4.8 2.5 -6.1 -3.3 -6.1 -7.0 -7.2 -6.5 -8.0 -7.7 -3.0 -1.2 -7.2 -7.8 8.1 -6.5 -4.3 -7.9 -7.9 -1.1 2.3 -8.7 -6.7 -6.5 -6.7 2.2 1.3 -6.6 -6.7 -3.6 -5.1 -3.4 -4.9 -6.3
Exposure to tobacco smoke outside home 4.7 6.2 11.6 -3.3 -3.0 -0.3 1.8 0.3 -2.1 -1.7 -0.6 -2.2 -3.4 -3.0 -3.0 -2.9 -0.2 -1.0 -3.2 -3.1 2.8 -3.4 -2.1 -3.0 -3.0 -1.1 0.1 -2.8 -3.1 -3.1 -3.1 0.3 -0.2 -3.2 -3.3 -2.4 -2.6 -2.3 -2.7 -3.2
Comparative body size at age 10 1.4 3.8 11.0 3.1 2.2 -0.7 -0.1 -0.9 2.5 0.8 2.3 2.8 2.2 2.9 3.3 3.0 1.8 0.7 2.5 2.6 -2.4 1.9 1.7 2.4 2.4 2.5 -0.6 2.4 1.3 1.4 1.9 -1.4 -1.4 0.8 1.9 -0.0 -0.0 0.5 0.2 1.8
Number of full brothers 1.3 1.7 8.6 -2.2 -1.6 -0.1 -0.6 -1.4 -0.3 0.8 -0.1 -1.4 -1.6 -2.2 -1.7 -1.6 -1.2 -2.1 -0.6 -1.3 1.2 -0.7 -2.0 -1.4 -1.4 -2.9 -1.3 -1.2 -0.4 -0.9 -1.0 0.5 0.1 -0.9 -1.0 -0.7 0.5 -0.3 -0.5 -1.3
Worry too long after embarrassment 0.9 1.5 5.0 -0.5 -0.8 -1.7 -0.3 -0.8 -0.2 -0.5 1.6 0.5 -0.6 -1.5 -0.2 -0.1 1.1 -0.2 -1.4 -0.8 0.6 -1.8 -0.4 -0.8 -0.8 1.1 -0.4 -0.6 -1.9 -1.4 -1.7 -1.6 -1.9 -0.8 -1.8 -1.7 -1.5 -2.2 -1.9 -0.7
Seen a psychiatrist for nerves, anxiety, tension or depression 1.9 2.5 5.6 -1.8 -2.2 -0.7 1.0 -1.8 -0.5 0.4 0.1 -1.1 -2.2 -2.4 -1.9 -1.5 -0.5 -1.8 -0.9 -1.6 1.6 -1.8 -1.9 -1.9 -1.9 -1.6 -1.5 -1.9 -1.3 -1.9 -1.6 0.2 -0.9 -1.8 -1.5 -2.1 -1.0 -1.2 -1.7 -2.3
Wheeze or whistling in the chest in last year 4.0 7.1 19.3 2.6 4.2 1.4 -0.1 0.8 1.5 1.0 -0.1 2.7 3.8 2.9 2.6 3.2 4.4 3.4 1.9 3.0 -2.9 3.4 3.9 3.5 3.5 3.0 2.5 3.2 1.5 2.7 2.2 -0.5 1.2 3.0 2.3 2.8 1.6 0.9 2.4 3.4
Number of children fathered 1.0 1.1 5.0 -0.8 -1.2 -0.5 0.5 -1.1 -0.4 0.8 0.7 -0.3 -1.7 -1.2 -0.6 -0.7 -0.3 -1.4 -0.4 -0.9 0.6 -1.3 -1.3 -0.9 -0.9 -2.2 -1.7 -0.8 -0.5 -1.0 -1.0 -0.6 -1.0 -1.3 -1.1 -1.4 -0.2 -1.1 -1.0 -2.1
Reason for reducing amount of alcohol drunk: Health precaution 2.5 2.9 6.3 1.4 2.1 0.4 -0.5 0.0 1.2 0.2 0.3 1.0 2.2 1.3 1.6 1.5 -0.2 1.0 2.2 2.1 -2.0 2.4 1.6 2.1 2.1 0.5 0.8 2.3 2.0 2.1 2.3 0.7 1.2 2.2 2.5 2.1 1.4 2.3 2.1 2.5
Age at first live birth 0.9 1.6 3.6 1.2 1.8 0.8 0.6 -0.4 -0.0 -0.1 0.3 0.8 1.5 1.4 1.0 0.9 -1.3 0.8 1.5 1.7 -1.4 1.8 1.1 1.5 1.5 0.8 0.2 1.3 1.8 1.9 1.6 -0.7 0.1 1.3 1.5 1.7 1.8 1.3 1.7 0.9
Pulse wave peak to peak time 0.4 0.4 4.5 -0.5 0.3 0.0 -1.1 -0.0 1.4 2.1 -1.0 0.1 0.3 0.1 0.1 0.3 1.2 1.1 -0.2 -0.2 0.2 -0.0 0.7 -0.0 -0.0 -0.1 1.1 -0.0 -0.9 -0.5 -0.4 0.2 0.2 -0.1 -0.3 -0.2 -1.0 -0.4 -0.6 0.6
Health satisfaction 0.6 0.8 4.6 0.7 -0.0 -1.9 -1.0 -0.6 0.1 -0.1 -0.0 0.2 1.0 0.1 0.3 0.6 2.1 -1.5 0.6 0.5 -0.7 1.0 -1.1 0.4 0.4 0.9 -0.6 0.3 1.0 1.0 0.7 0.0 0.1 1.4 0.5 1.1 1.6 0.7 1.1 1.0
Shortness of breath walking on level ground 1.5 1.8 4.4 1.9 1.2 -1.1 -1.1 -0.4 0.9 0.4 1.0 1.1 1.6 2.1 1.5 1.7 1.8 0.3 1.4 1.4 -1.5 1.6 1.0 1.5 1.5 1.6 0.3 1.3 1.5 1.7 1.6 -0.2 0.1 1.7 1.5 1.4 1.3 1.3 1.4 1.8
Qualifications: College or University degree 0.6 1.8 5.1 2.2 1.1 -0.4 -1.4 0.2 0.4 -1.1 0.5 0.3 1.3 2.0 1.8 1.5 -1.4 0.7 1.6 1.4 -1.1 1.6 0.7 1.1 1.1 2.3 0.4 0.6 1.7 2.0 1.9 -0.5 0.0 1.1 1.7 1.7 1.0 2.0 1.6 1.0
Eye problems/disorders: None of the above 0.7 0.8 2.8 -1.1 -0.3 0.7 0.0 -1.4 -0.1 0.9 -0.4 0.0 -0.4 -0.7 -0.8 -0.9 -0.7 0.8 -1.2 -0.8 1.0 -1.5 0.4 -0.8 -0.8 0.1 0.7 -0.7 -1.4 -1.0 -1.5 -0.9 -0.5 -0.5 -1.5 -0.7 -0.9 -1.7 -1.0 -0.3
Mouth/teeth dental problems: Loose teeth 0.7 0.8 1.7 -1.0 -1.3 -0.5 1.1 -0.3 -0.4 -0.0 0.5 -0.6 -1.1 -1.2 -0.5 -0.9 -0.4 -1.1 -1.0 -1.2 1.0 -0.5 -1.0 -1.1 -1.1 -0.6 -0.9 -0.9 -0.8 -1.3 -0.9 0.7 -0.2 -1.0 -0.8 -1.3 -0.8 -0.7 -1.1 -0.7
Emphysema/chronic bronchitis 1.1 1.3 8.3 -0.9 -0.5 1.5 1.9 2.3 -1.2 -1.3 -2.9 -1.4 0.2 -0.6 -1.3 -0.8 0.8 0.7 -1.2 -0.9 1.1 -0.0 -0.1 -0.8 -0.8 -0.0 1.6 -1.0 -0.7 -0.7 -0.5 2.1 1.8 0.3 -0.1 0.3 -0.6 0.3 0.1 0.7
Medication for pain relief, constipation, heartburn 0.5 0.9 4.4 -0.8 -1.2 0.3 -2.0 -0.7 0.2 0.6 0.1 -1.3 -0.6 -0.6 -0.2 -0.3 -1.2 -1.5 0.2 -0.8 0.5 0.2 -1.3 -0.7 -0.7 -2.1 -1.0 -0.7 0.9 0.1 0.5 1.8 1.3 -0.1 0.6 0.3 0.9 1.4 0.8 -0.7
Neck or shoulder pain in last month 0.8 1.2 6.7 0.7 1.4 2.0 1.6 0.7 -0.6 0.6 -1.1 0.7 0.8 0.9 0.2 0.3 -0.6 2.6 -0.8 0.2 0.1 -0.4 2.3 0.4 0.4 1.9 2.1 0.2 -1.1 -0.3 -0.9 -1.1 -0.2 0.1 -0.7 0.1 -1.2 -1.3 -0.2 0.4
Medication: Blood pressure 4.6 8.0 14.8 3.3 3.3 -0.7 -1.9 0.3 2.1 0.3 0.5 2.1 3.7 2.9 3.0 2.9 2.2 0.9 3.5 3.5 -3.5 3.4 1.9 3.5 3.5 1.6 0.2 3.4 3.6 3.8 3.7 -0.0 0.7 3.8 3.6 3.2 3.5 3.0 3.4 3.7
Angina (self-reported) 1.1 1.5 4.5 1.2 1.1 0.7 1.2 1.2 -0.7 -1.3 -0.3 0.3 1.8 1.1 0.4 0.7 1.8 -0.2 0.9 1.1 -1.0 2.1 0.4 1.1 1.1 0.5 0.5 1.2 1.3 1.2 1.3 1.3 1.4 1.7 1.5 1.5 1.4 1.2 1.6 1.9
Migraine (self-reported) 0.4 0.5 3.9 0.8 0.7 0.2 -0.2 0.2 -0.5 -0.7 -0.4 0.2 0.3 1.1 0.2 0.2 -1.7 1.5 0.1 0.4 0.2 -0.4 0.7 0.0 0.0 2.0 0.7 -0.3 0.1 0.7 0.0 -1.5 -1.0 0.5 -0.3 0.8 0.9 -0.1 0.3 0.3
Medication: Ibuprofen 0.2 0.3 1.2 -0.1 -0.0 0.1 0.9 -0.2 -0.6 0.3 -0.8 -0.3 -0.2 -0.0 -0.2 -0.3 -1.1 0.5 -0.8 -0.3 0.5 -0.8 0.0 -0.4 -0.4 0.4 0.3 -0.5 -0.5 -0.3 -0.8 -0.7 -0.3 0.0 -0.8 -0.1 -0.2 -0.9 -0.1 -0.3
Medication: Allopurinol 0.5 0.7 5.3 -0.3 0.7 0.5 0.8 2.2 -0.6 -1.1 -1.4 -0.3 -0.2 -0.0 -0.4 -0.3 0.0 1.9 -0.6 -0.1 0.4 -0.1 0.9 -0.0 -0.1 1.3 2.3 0.2 -0.6 0.2 -0.4 -0.6 0.5 -0.4 -0.4 1.0 0.0 0.0 0.3 -0.2
Medication: Omeprazole 1.0 1.2 2.9 0.5 1.7 0.0 -0.0 -0.2 0.9 0.4 0.9 1.7 1.3 1.0 1.0 1.1 0.7 1.1 1.2 1.7 -1.5 1.2 1.6 1.7 1.7 1.0 -0.0 1.6 1.1 1.1 1.3 -1.3 -1.1 0.4 1.3 0.1 0.2 0.5 0.3 1.1
Medication: Seretide 50 evohaler 13.1 15.1 26.0 4.6 4.7 -1.2 -3.3 -0.8 3.1 2.7 2.5 4.6 4.9 4.2 5.1 5.1 4.5 1.7 3.9 4.8 -5.0 3.9 3.8 5.1 5.1 2.3 -0.4 4.8 4.3 4.7 4.1 -1.9 -0.5 5.0 4.0 3.3 4.2 2.0 3.8 4.3
Mean time to correctly identify matches 0.2 0.3 1.6 -0.2 0.7 -0.7 0.1 0.5 1.1 0.9 0.4 0.8 0.5 -0.2 0.4 0.5 0.1 0.9 0.3 0.5 -0.7 0.3 0.8 0.8 0.8 0.8 0.8 1.3 -0.3 0.2 0.2 -0.7 -0.5 -0.2 -0.0 0.1 -0.3 -0.1 -0.4 0.4
Heart disease (mother) 0.3 0.3 4.2 0.6 0.1 0.9 0.6 -0.1 -0.7 -0.9 2.1 0.7 0.2 0.2 0.7 0.1 0.1 -0.7 -0.1 0.0 -0.4 0.0 0.2 0.3 0.3 -0.8 -0.7 0.8 -0.2 -0.3 -0.3 -0.1 -0.2 0.1 -0.1 -0.6 0.2 -0.9 -0.3 0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria 2.5 3.0 5.6 -2.2 -2.2 -0.3 0.9 1.7 -2.2 -1.3 -1.5 -2.2 -2.1 -2.1 -2.3 -2.4 0.5 -1.7 -2.1 -2.2 1.9 -1.4 -2.4 -2.2 -2.2 -2.0 -0.5 -2.2 -1.5 -1.7 -1.7 1.7 1.2 -1.2 -1.7 -0.6 -0.1 -0.9 -0.8 -1.4
Whole body fat mass 0.6 2.7 8.6 -1.2 -1.8 1.0 2.9 0.9 -1.9 -1.6 -2.1 -2.4 -1.7 -1.6 -2.4 -1.9 -1.7 0.1 -1.2 -1.9 2.2 -1.3 -0.9 -2.0 -2.0 0.8 1.3 -2.7 -1.5 -1.5 -1.1 1.2 0.7 -1.9 -1.0 -0.8 -2.0 0.4 -1.2 -1.3
Leg fat mass (right) 0.2 0.8 4.7 0.4 -0.5 0.6 2.2 1.1 -1.2 -1.5 -1.3 -1.4 -0.1 0.0 -0.6 -0.4 -1.2 0.5 0.1 -0.5 0.8 0.2 -0.0 -0.6 -0.6 1.8 1.4 -1.2 -0.2 -0.0 0.3 0.9 0.8 -0.3 0.3 0.5 -0.8 1.5 0.0 0.3
Arm predicted mass (right) 6.5 33.4 72.7 -6.0 -6.4 2.3 5.1 2.8 -6.2 -3.4 -6.3 -7.0 -7.0 -6.4 -7.8 -7.5 -3.0 -0.8 -7.2 -7.7 8.0 -6.2 -4.1 -7.8 -7.8 -0.9 2.7 -8.5 -6.7 -6.4 -6.7 2.3 1.6 -6.3 -6.6 -3.3 -5.2 -3.4 -4.7 -6.0
Pulse rate, automated reading 0.7 2.4 5.2 2.0 1.6 0.4 0.1 -1.0 1.3 0.7 1.0 1.6 1.7 1.8 1.9 2.0 -1.0 0.5 2.2 2.1 -2.1 1.6 1.2 2.0 2.0 0.6 -0.3 2.1 2.1 1.9 2.2 -0.4 -0.3 1.4 2.3 1.0 1.1 1.8 1.4 1.5
Alcohol intake frequency. 0.2 0.4 3.3 -0.0 0.6 0.1 -0.4 -0.6 0.4 1.0 -0.8 0.1 0.2 0.1 0.3 0.5 -0.1 1.4 -0.2 -0.1 0.2 0.4 1.0 0.1 0.1 1.8 1.4 -0.2 -0.2 0.4 -0.0 -0.4 0.4 0.1 -0.1 0.9 0.1 0.1 0.5 0.1
Comparative height size at age 10 12.7 70.2 125.4 -9.3 -9.7 2.9 6.4 4.0 -8.7 -5.3 -6.6 -9.1 -10.5 -9.3 -10.5 -10.4 -3.6 -2.5 -10.5 -11.0 10.8 -10.3 -6.7 -10.8 -10.8 -4.3 1.3 -11.2 -9.6 -10.2 -10.3 2.8 0.8 -9.8 -10.0 -6.9 -7.5 -6.5 -7.8 -9.7
Number of full sisters 1.8 2.2 5.0 -1.2 -1.4 1.5 2.2 0.6 -1.7 -1.3 -2.1 -1.3 -1.5 -1.5 -1.8 -1.8 -0.5 0.1 -1.7 -1.8 1.8 -1.5 -0.8 -1.7 -1.7 -1.2 0.5 -1.8 -1.6 -1.9 -1.8 1.0 0.6 -1.7 -1.4 -1.3 -2.1 -1.0 -1.2 -1.4
Suffer from ‘nerves’ 0.8 1.2 3.5 -1.3 -0.7 0.1 0.7 0.3 -1.0 0.3 -1.3 -0.8 -1.0 -0.9 -1.4 -1.1 -0.3 0.6 -1.9 -1.4 1.6 -1.3 -0.5 -1.5 -1.5 1.2 1.2 -1.5 -1.6 -0.9 -1.7 -0.6 -0.1 -0.3 -1.9 0.1 -0.4 -1.5 -0.5 -0.8
Overall health rating 0.3 0.7 3.5 0.1 0.3 -0.7 1.8 -0.9 0.6 0.7 0.7 1.5 0.4 -0.3 0.1 0.5 1.9 -0.5 0.1 0.6 -0.8 -0.3 0.1 0.6 0.6 0.8 -1.2 0.2 -0.2 -0.2 -0.2 -1.5 -1.7 0.0 -0.3 -1.0 -0.6 -1.0 -0.8 -0.1
Chest pain or discomfort 0.2 0.3 2.4 0.2 0.3 -0.6 0.5 0.4 0.6 -0.4 0.3 0.1 0.4 0.2 0.2 0.5 1.6 -0.2 0.6 0.6 -0.5 0.7 -0.1 0.5 0.5 1.3 0.1 0.2 0.5 0.4 0.7 0.4 0.1 0.2 0.8 0.2 -0.2 0.9 0.2 0.6
Had major operations 0.8 0.9 3.8 1.0 0.4 -1.1 -0.3 1.5 -0.4 -1.9 0.0 0.3 0.9 1.4 0.9 1.0 1.2 -0.1 0.8 0.7 -0.9 1.1 0.4 0.9 0.9 0.6 -0.1 0.4 1.4 1.2 1.2 0.4 0.3 1.3 1.3 0.9 1.0 1.2 1.2 1.2
Age at last live birth 0.4 0.6 3.6 0.4 0.4 1.6 1.9 0.1 -1.0 -0.4 -0.9 -0.6 0.6 0.5 0.0 -0.0 -1.4 -0.0 0.3 0.4 -0.1 1.1 -0.2 0.2 0.2 -0.2 -0.0 0.2 1.0 0.7 0.6 0.9 1.1 0.7 0.8 1.0 1.2 1.0 1.2 0.4
Family relationship satisfaction 2.5 3.1 10.7 -3.3 -2.0 -0.4 -0.3 -0.4 -0.6 0.9 -1.4 -1.6 -1.9 -2.4 -2.3 -2.0 0.3 -0.4 -2.6 -2.3 2.5 -2.1 -1.6 -2.5 -2.5 -0.9 0.1 -2.6 -1.9 -2.0 -2.3 0.8 0.2 -1.4 -2.4 -1.1 -1.1 -1.5 -1.4 -1.5
Leg pain on walking 0.3 0.4 3.5 0.5 -0.5 -0.9 -0.4 0.8 -0.9 -1.9 -0.0 -0.6 0.2 0.3 -0.2 -0.2 0.3 -1.1 0.3 -0.2 -0.2 0.4 -0.9 0.0 0.0 0.4 -0.1 -0.0 0.5 0.4 0.5 0.6 0.5 0.6 0.4 0.7 0.5 1.0 0.6 0.4
Qualifications: NVQ or HND or HNC or equivalent 0.3 0.4 3.3 0.3 -0.6 -1.0 0.4 1.5 -0.8 -1.8 0.5 0.0 -0.3 -0.1 -0.4 -0.5 0.9 -0.9 -0.3 -0.3 0.2 -0.4 -0.8 -0.4 -0.4 -0.2 -0.7 -0.3 -0.5 -0.5 -0.2 -0.0 -0.6 -0.4 -0.4 -0.8 -0.4 -0.5 -0.9 -0.1
Commuting to job workplace: Car/motor vehicle 0.6 0.6 3.4 -0.7 -0.4 1.8 1.2 0.6 -1.6 -1.1 -0.5 -1.2 -0.2 -0.3 -0.7 -0.7 -0.3 -0.5 -1.0 -0.8 0.6 -0.2 -0.4 -0.6 -0.6 -1.0 0.5 -0.5 -0.4 -0.6 -0.6 1.5 1.7 -0.1 -0.4 0.3 0.6 -0.2 0.3 -0.2
Illness, injury, bereavement, stress in last 2 years 3.9 4.7 10.1 1.8 3.1 -0.2 -2.2 -1.0 3.0 3.2 1.5 2.8 2.4 2.3 3.0 3.0 0.5 2.1 2.4 2.8 -2.7 2.3 3.2 3.0 3.0 0.8 0.8 3.1 1.7 2.2 2.1 -1.6 -0.4 1.6 2.2 1.2 0.3 0.8 1.4 1.8
Medication: Aspirin 2.8 3.7 8.4 2.4 2.6 -0.0 0.3 0.5 0.9 -0.6 1.5 2.1 2.7 2.5 1.9 2.1 2.3 0.8 2.0 2.4 -2.5 2.8 2.0 2.7 2.7 1.9 0.8 2.9 1.5 2.0 2.1 -0.5 0.3 2.2 2.2 1.6 0.7 1.0 1.6 2.7
Supplements: Vitamin C 0.5 0.6 5.6 -0.0 0.0 0.5 0.4 -0.6 -0.4 -0.1 0.7 0.7 -0.3 0.1 -0.3 -0.5 -2.4 0.9 -0.4 0.0 0.3 -1.4 0.8 -0.2 -0.2 0.5 0.1 -0.4 -0.4 -0.1 -0.7 -2.1 -1.7 -0.2 -0.9 -0.5 -0.1 -0.8 -0.6 -0.5
Knee pain experienced in last month 0.3 0.5 1.2 0.6 0.8 -0.4 -0.3 0.1 0.9 0.8 0.0 0.3 0.7 0.8 1.1 1.0 -0.1 1.1 0.3 0.6 -0.8 0.7 0.8 0.9 0.9 0.8 1.1 0.7 0.4 0.5 0.6 0.1 0.5 0.4 0.7 0.6 -0.3 0.8 0.6 0.7
Hypertension (Self-reported) 5.8 16.2 29.7 5.1 4.8 -0.4 -1.3 1.4 3.0 -0.1 1.5 3.5 5.3 4.9 5.1 5.0 1.9 2.2 4.9 5.2 -5.0 5.4 3.8 5.2 5.2 3.7 0.4 4.8 4.8 4.9 5.4 -0.4 0.3 4.3 5.4 3.4 2.7 4.2 3.9 4.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.6 0.7 3.2 0.2 0.9 -0.3 -0.3 -0.5 0.5 1.1 0.4 0.4 1.3 1.0 0.7 0.6 0.2 0.7 0.1 0.8 -0.6 0.9 0.7 0.8 0.8 0.8 0.4 0.6 1.0 1.1 0.8 -0.1 0.1 1.8 0.9 1.0 1.3 0.6 1.1 1.7
Illnesses of father: Heart disease 3.9 5.4 16.3 2.8 1.9 2.2 1.0 3.4 -2.1 -2.5 -2.3 -0.8 2.6 2.8 1.3 1.1 -0.6 2.0 0.7 1.2 -0.5 2.3 1.8 1.0 1.0 2.7 2.9 0.3 2.4 2.8 2.0 1.5 3.0 3.3 2.2 4.0 2.9 2.9 3.8 3.0
Illnesses of siblings: Diabetes 1.3 1.5 9.0 0.2 1.7 -0.1 -1.3 -1.7 2.5 3.0 1.4 2.1 0.8 0.6 1.1 1.2 0.3 1.5 1.0 1.4 -1.2 0.5 1.8 1.4 1.3 0.4 -0.1 1.2 0.7 1.0 0.7 -2.1 -1.5 0.4 0.5 0.1 0.2 -0.5 0.2 0.2
Smoking status: Previous 1.0 1.6 3.6 1.4 1.2 -1.2 -1.5 1.4 1.2 -0.3 0.8 1.1 1.2 1.5 1.6 1.5 1.9 0.6 1.1 1.2 -1.5 1.6 0.7 1.5 1.5 1.9 0.0 1.3 1.3 1.4 1.6 -0.1 -0.0 0.6 1.3 1.1 1.3 1.4 0.9 0.9
Forced expiratory volume in 1-second (FEV1), predicted 7.8 16.3 33.5 -4.7 -4.4 0.7 1.4 1.5 -3.7 -2.5 -4.2 -4.3 -5.2 -4.6 -5.4 -5.2 -3.6 -0.5 -5.3 -5.2 5.5 -5.1 -3.1 -5.4 -5.4 -0.5 1.2 -5.8 -4.6 -4.3 -4.9 0.2 -0.1 -4.4 -5.1 -2.5 -2.8 -3.0 -3.4 -4.8
Whole body fat-free mass 8.2 47.1 100.0 -7.4 -8.0 2.0 5.3 2.9 -6.8 -4.0 -6.6 -8.1 -8.5 -7.7 -9.3 -8.9 -3.6 -1.5 -8.4 -9.1 9.4 -7.8 -5.3 -9.2 -9.2 -1.5 2.4 -10.0 -7.9 -7.9 -7.9 2.4 1.1 -8.0 -7.9 -4.7 -6.4 -4.1 -6.2 -7.5
Leg fat-free mass (right) 7.9 42.0 87.4 -7.1 -7.5 1.9 5.2 2.2 -6.2 -3.5 -6.0 -7.7 -8.0 -7.4 -8.9 -8.4 -3.7 -1.5 -7.8 -8.5 8.8 -7.4 -5.1 -8.6 -8.6 -1.5 2.1 -9.3 -7.4 -7.5 -7.4 2.2 0.8 -7.8 -7.4 -4.7 -6.2 -3.8 -6.0 -7.2
Arm fat percentage (left) 0.4 1.4 4.8 1.8 0.9 -0.3 0.8 -0.4 0.9 -0.0 0.7 0.5 1.4 1.3 1.1 1.5 -0.3 0.4 2.2 1.4 -1.3 1.6 0.9 1.3 1.3 1.7 0.3 0.9 1.4 1.3 2.0 0.2 0.0 0.8 2.0 0.7 0.2 2.2 0.8 1.5
Average weekly red wine intake 1.2 1.8 7.0 1.0 0.7 -2.2 -2.0 -2.1 2.6 2.4 2.6 1.8 0.5 1.2 1.8 1.5 0.1 0.2 1.4 1.3 -1.2 0.1 0.8 1.1 1.1 0.8 -0.9 1.2 0.4 0.6 0.8 -2.0 -2.3 0.0 0.5 -0.7 -0.7 -0.3 -0.6 0.3
Handedness (chirality/laterality): Left-handed 0.3 0.4 2.4 -0.2 -0.1 -1.5 -0.4 -0.5 0.1 -0.3 1.3 0.9 -0.5 -0.0 0.2 -0.1 0.5 -0.7 0.1 0.2 -0.4 -0.5 -0.1 0.2 0.2 -0.2 -1.1 0.3 -0.5 -0.3 -0.4 -1.2 -1.2 -0.3 -0.7 -0.6 0.3 -1.0 -0.8 -0.7
Mood swings 0.7 1.3 3.9 -0.7 -0.3 -1.4 -0.2 -1.4 1.3 2.0 2.0 1.0 -0.3 -0.9 -0.0 0.3 1.7 0.1 -0.9 -0.3 0.4 -1.1 0.5 -0.4 -0.4 0.4 -0.2 -0.3 -1.6 -1.3 -1.2 -1.1 -1.7 -0.7 -1.2 -1.7 -1.7 -1.9 -1.9 -0.2
Loneliness, isolation 0.5 0.7 2.2 -0.7 -0.5 -1.1 -0.0 0.0 0.1 -0.7 0.9 0.2 -0.5 -1.5 -0.6 -0.5 0.7 0.3 -0.9 -0.5 0.7 -1.2 -0.1 -0.7 -0.7 0.5 -0.0 -0.8 -1.2 -0.9 -1.1 -0.9 -1.3 -0.3 -1.3 -1.0 -1.0 -1.4 -1.3 -0.1
Long-standing illness, disability or infirmity 2.2 3.3 7.8 1.6 1.5 -1.3 -0.5 -0.3 1.6 -0.0 1.0 1.6 2.0 1.0 1.8 2.2 2.4 -0.5 2.7 2.3 -2.7 2.2 0.6 2.4 2.4 0.5 -1.4 2.1 2.8 2.3 2.8 -0.1 -0.3 1.8 2.8 1.1 1.7 2.3 1.7 1.9
Ever had bowel cancer screening 0.5 0.6 3.1 -0.8 -0.6 1.1 1.7 -0.3 -0.8 0.3 -0.6 -0.6 -0.8 -0.7 -1.0 -0.7 -0.2 -0.2 -0.7 -0.7 0.6 -0.9 -0.1 -0.6 -0.6 -1.6 0.1 -0.8 -0.6 -1.1 -0.8 1.1 0.7 -0.9 -0.4 -0.8 -1.0 -0.3 -0.5 -0.7
Diabetes diagnosed by doctor 0.7 1.2 4.0 0.4 0.7 0.1 1.1 1.9 -0.0 -1.2 -1.2 -0.4 1.0 -0.0 0.6 0.7 0.7 0.2 1.0 0.7 -0.7 1.8 -0.0 0.8 0.8 0.4 0.6 0.6 1.4 1.2 1.4 1.5 1.5 1.1 1.6 1.5 0.9 2.0 1.6 1.3
Ever had stillbirth, spontaneous miscarriage or termination 1.3 1.4 7.5 0.7 -0.1 0.7 0.3 1.5 -0.9 -1.8 -1.2 -0.8 0.5 0.6 0.1 -0.1 -1.3 -1.2 1.4 0.7 -0.5 1.6 -0.8 0.3 0.3 -0.5 -0.8 0.0 2.2 1.4 1.8 1.4 1.0 0.8 1.9 1.2 1.6 2.7 1.8 0.3
Friendships satisfaction 0.6 0.7 2.5 -1.5 -0.7 0.2 0.4 -0.3 -0.3 0.3 -1.0 -0.8 -0.4 -1.2 -0.9 -0.8 -0.2 0.6 -1.6 -1.2 1.4 -1.0 -0.0 -1.2 -1.2 0.1 1.1 -1.3 -1.1 -0.9 -1.3 0.5 0.4 -0.0 -1.2 -0.1 -0.3 -0.8 -0.3 -0.1
Qualifications: nursing, teaching 1.1 1.7 10.2 1.3 0.5 1.6 -0.4 1.0 -1.2 -3.2 -2.2 -1.3 0.8 0.8 0.3 0.2 -2.6 2.1 0.2 0.1 0.4 0.3 0.9 -0.1 -0.1 2.3 2.3 -0.6 0.7 1.0 0.7 0.6 1.2 0.6 0.7 1.8 0.9 1.9 1.4 0.5
Commuting to job workplace: Walk 0.7 0.8 5.5 0.7 0.2 -2.3 -1.4 -0.6 1.3 0.4 0.5 1.1 -0.2 0.3 0.4 0.5 0.8 0.4 0.5 0.3 -0.2 -0.1 0.0 0.2 0.2 1.7 -0.5 0.1 -0.6 -0.1 -0.1 -1.7 -2.0 -0.7 -0.4 -0.9 -1.4 -0.9 -1.1 -0.6
Eye problems/disorders: Cataract 0.4 0.5 3.9 0.1 -0.3 -1.3 -1.0 0.1 0.2 -0.5 1.6 0.5 -0.6 -0.2 0.4 0.2 -0.2 -1.4 0.4 0.3 -0.5 0.3 -0.7 0.2 0.2 -0.5 -2.0 0.2 0.5 0.3 0.5 -0.8 -1.2 -0.3 0.1 -0.5 0.6 0.0 -0.3 -0.8
Mouth/teeth dental problems: Mouth ulcers 0.2 0.4 1.6 -0.9 -0.3 0.7 1.1 -1.2 -0.3 0.9 -0.3 -0.3 0.1 -1.3 -0.9 -0.9 -0.6 0.1 -0.5 -0.3 0.7 -0.8 -0.2 -0.7 -0.7 -0.6 0.0 -0.9 -0.5 -0.5 -0.7 -0.2 -0.2 0.3 -0.6 -0.3 -0.4 -0.6 -0.3 0.1
Medication for cholesterol 2.8 4.2 8.2 -2.5 -2.3 0.8 0.8 -0.2 -2.3 -0.3 -1.6 -2.3 -2.7 -2.6 -2.6 -2.6 -1.7 -0.6 -2.8 -2.9 2.8 -2.4 -1.8 -2.8 -2.8 -2.0 0.5 -2.4 -2.1 -2.0 -2.7 0.9 1.0 -1.5 -2.8 -0.5 0.4 -1.9 -1.0 -2.4
Medication: Laxatives (e.g. Dulcolax, Senokot) 2.3 2.7 10.6 -1.3 -0.2 1.0 2.8 1.0 -1.1 -1.2 -0.1 0.8 -1.5 -1.6 -1.1 -1.1 -0.2 0.9 -1.7 -0.8 0.7 -2.0 0.6 -0.6 -0.6 -0.2 0.1 -0.4 -2.6 -2.1 -2.3 -1.9 -1.7 -2.2 -2.4 -2.3 -2.4 -3.3 -2.6 -2.0
Back pain experienced in last month 2.7 3.9 11.1 -2.1 -2.4 -1.4 0.8 -1.9 0.2 1.3 1.0 -0.4 -2.5 -2.4 -2.1 -1.7 -0.3 -1.9 -1.5 -1.7 1.4 -2.6 -1.6 -1.7 -1.7 -1.7 -1.9 -1.8 -2.0 -2.5 -2.0 -0.9 -2.2 -2.8 -2.1 -3.3 -2.4 -2.2 -3.0 -2.7
Mineral and other dietary supplements 0.2 0.3 1.1 -0.7 -0.4 -0.3 0.1 0.1 0.1 0.9 0.1 0.0 -0.4 -0.6 -0.4 -0.2 0.1 -0.7 -0.6 -0.5 0.3 -0.2 -0.6 -0.4 -0.4 -0.3 -0.2 -0.2 -1.0 -0.9 -0.8 0.1 -0.1 -0.5 -0.8 -0.8 -0.8 -1.1 -0.8 -0.4
Breast cancer (self-reported) 2.8 3.4 8.8 -2.1 -2.4 -0.1 0.5 -0.3 -1.2 -0.5 -1.4 -1.3 -2.4 -2.0 -2.1 -2.1 -0.8 -0.8 -2.0 -2.2 2.1 -3.0 -1.5 -2.3 -2.3 -1.1 -0.2 -2.2 -2.3 -2.3 -2.3 -0.2 -0.8 -2.3 -2.4 -2.0 -1.8 -1.8 -2.3 -1.9
Asthma (self-reported) 25.3 50.4 98.2 8.3 9.9 -0.5 -3.6 0.3 5.3 3.4 2.8 8.6 9.4 8.1 8.8 9.3 9.6 5.6 6.8 8.9 -8.7 7.8 8.2 9.4 9.4 7.2 1.4 8.6 6.6 8.3 7.0 -4.3 -0.8 8.6 6.6 6.4 6.0 2.8 6.6 8.0
Osteoporosis (self-reported) 0.9 1.1 4.2 -0.8 -0.3 0.2 0.6 0.7 -0.6 -0.7 -0.1 0.4 -0.4 -1.0 -0.4 -0.6 1.1 0.6 -1.2 -0.8 0.6 -1.7 0.1 -0.6 -0.6 0.3 0.0 -0.5 -1.7 -1.5 -1.6 -1.1 -1.2 -1.0 -1.5 -1.7 -1.8 -2.0 -1.7 -0.7
Osteoarthritis (self-reported) 3.6 4.7 10.0 2.1 1.8 -2.3 -1.8 -2.5 3.0 1.9 3.2 2.6 2.1 1.7 2.5 2.7 0.2 -0.3 3.1 3.0 -3.0 1.6 1.1 2.7 2.7 0.8 -1.9 2.6 2.7 2.4 2.7 -1.9 -2.1 1.5 2.5 0.4 1.4 1.6 1.0 1.5
Medication: Aspirin 2.0 2.7 6.2 2.2 2.1 -0.0 0.4 0.7 0.6 -1.0 1.6 2.0 2.2 2.1 1.5 1.7 2.2 0.3 1.7 2.0 -2.2 2.3 1.5 2.3 2.3 1.7 0.3 2.5 1.3 1.7 1.7 -0.6 -0.1 1.7 1.8 1.1 0.4 0.7 1.1 2.1
Medication: Gliclazide 0.5 0.6 3.2 -0.3 -0.9 -0.7 0.9 1.6 -1.0 -1.8 -0.4 -1.0 -0.4 -1.0 -0.6 -0.4 -0.0 -1.2 0.2 -0.3 0.1 0.1 -1.2 -0.3 -0.3 -1.0 -0.7 -0.5 0.7 0.1 0.4 1.0 0.5 -0.0 0.4 0.2 0.8 1.1 0.4 -0.1
Illnesses of father: None of the above (group 1) 1.8 2.2 6.4 -2.0 -1.5 -0.1 -0.1 -0.5 0.2 0.4 0.5 -0.2 -1.9 -1.6 -1.5 -1.5 -1.2 -0.4 -1.1 -1.4 1.3 -2.0 -0.8 -1.3 -1.3 -1.2 -0.9 -1.1 -2.0 -2.1 -1.7 -0.7 -1.5 -2.4 -1.9 -2.4 -1.9 -1.9 -2.5 -2.3
Smoking status: Current 0.8 1.2 4.0 -0.8 -1.5 0.5 1.1 -0.5 -1.7 -1.9 -0.9 -1.2 -1.2 -1.6 -1.5 -1.5 -1.1 -1.8 -0.4 -1.1 1.0 -0.8 -1.5 -1.2 -1.2 -2.0 -0.8 -1.0 -0.3 -0.8 -0.6 1.1 0.6 -0.7 -0.4 -0.6 -0.2 0.1 -0.3 -0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.8 1.6 7.5 -0.1 -0.3 -1.8 -0.8 -1.1 1.7 0.8 1.7 0.8 -1.1 -0.6 0.1 0.0 -0.5 -0.0 0.4 0.1 0.1 -1.4 -0.1 -0.2 -0.2 0.7 -0.8 -0.1 -1.4 -1.3 -0.7 -1.7 -2.5 -2.2 -0.8 -2.4 -2.7 -1.2 -2.6 -1.4
Whole body water mass 8.4 48.0 102.0 -7.4 -8.0 2.0 5.4 3.0 -6.9 -4.0 -6.8 -8.2 -8.5 -7.8 -9.4 -9.0 -3.6 -1.5 -8.5 -9.2 9.5 -7.8 -5.3 -9.3 -9.3 -1.5 2.5 -10.1 -8.0 -7.9 -8.0 2.5 1.1 -8.0 -8.0 -4.7 -6.5 -4.2 -6.2 -7.5
Leg predicted mass (right) 7.9 42.1 88.4 -7.1 -7.6 2.0 5.3 2.2 -6.2 -3.5 -6.1 -7.7 -8.0 -7.4 -8.9 -8.4 -3.7 -1.5 -7.8 -8.5 8.8 -7.3 -5.1 -8.6 -8.6 -1.5 2.1 -9.4 -7.4 -7.5 -7.4 2.2 0.8 -7.8 -7.4 -4.6 -6.2 -3.8 -5.9 -7.2
Arm fat mass (left) 0.4 1.7 6.0 -0.7 -1.5 0.5 2.4 0.7 -1.4 -1.3 -1.7 -2.1 -1.2 -1.2 -1.8 -1.4 -1.4 0.0 -0.8 -1.5 1.8 -0.9 -0.8 -1.6 -1.6 0.9 1.2 -2.2 -1.1 -1.1 -0.7 1.1 0.7 -1.5 -0.6 -0.5 -1.6 0.7 -1.0 -0.8
Number of self-reported non-cancer illnesses 6.4 11.1 29.8 4.1 4.3 -0.7 -0.9 0.3 2.8 1.3 1.0 3.8 4.7 3.5 4.0 4.7 5.5 1.7 3.5 4.2 -4.2 4.2 3.1 4.4 4.4 3.0 -0.0 3.8 3.2 3.6 3.6 -0.8 0.0 3.9 3.7 2.5 2.3 1.9 2.8 4.2
Average weekly champagne plus white wine intake 0.2 0.3 2.0 -0.9 -0.5 -0.3 -0.2 0.0 0.4 0.3 -0.6 -0.0 -0.2 -0.3 -0.4 -0.4 0.4 -0.2 -0.3 -0.3 0.2 -0.3 -0.3 -0.2 -0.2 -1.1 -0.2 -0.4 -0.6 -0.8 -0.4 0.4 -0.3 -0.5 -0.2 -1.1 -1.4 -0.5 -0.9 -0.2
Miserableness 1.9 3.2 9.8 -2.1 -1.6 -2.2 0.8 -0.9 0.9 1.6 0.9 0.2 -1.4 -2.7 -1.6 -1.0 2.3 -0.8 -1.9 -1.6 1.3 -2.2 -1.0 -1.5 -1.5 0.2 -0.6 -1.5 -2.7 -2.5 -2.2 -0.6 -1.7 -2.0 -2.4 -2.6 -2.6 -2.6 -3.1 -1.1
Guilty feelings 0.9 1.3 2.4 -1.2 -1.5 -1.3 0.1 -1.5 0.0 1.2 0.9 -0.7 -1.0 -1.5 -0.9 -0.6 0.8 -1.1 -1.5 -1.4 1.2 -1.4 -1.2 -1.4 -1.4 -0.1 -0.4 -1.4 -1.5 -1.5 -1.5 0.3 -0.6 -1.0 -1.5 -1.3 -0.9 -1.3 -1.5 -0.8
Wears glasses or contact lenses 0.4 0.4 1.8 1.3 0.3 -0.1 0.4 -0.3 0.1 0.1 0.8 0.1 0.3 1.0 0.6 0.6 -0.8 -0.4 1.3 0.8 -0.8 0.3 -0.2 0.7 0.7 -0.3 -0.6 0.7 1.0 0.7 0.9 -0.1 -0.0 0.2 1.0 0.2 0.3 0.9 0.6 0.2
Ever taken oral contraceptive pill 1.3 1.5 4.4 1.2 1.1 -0.1 -1.3 0.7 0.3 0.6 0.6 0.5 1.3 1.7 1.4 1.2 -0.4 -0.1 1.2 1.3 -1.3 1.2 0.5 1.3 1.3 -0.2 -0.5 1.3 2.0 1.8 1.5 -0.1 0.5 1.6 1.4 1.5 2.1 1.3 1.9 1.2
Hearing aid user 0.8 0.9 4.7 0.7 0.4 -1.5 -1.2 -2.2 1.2 1.4 1.6 1.4 0.3 0.3 0.9 0.9 0.2 -0.6 0.9 0.9 -1.1 0.1 -0.1 0.8 0.8 -0.4 -1.7 1.1 0.8 0.6 0.5 -1.4 -1.5 0.4 0.2 -0.3 1.2 -0.2 0.0 -0.1
Mother’s age at death 0.2 0.2 1.9 -0.2 -0.3 -1.4 -0.9 -1.4 0.6 0.7 0.7 -0.3 -0.1 -0.2 -0.2 -0.2 0.0 -0.6 0.4 0.1 -0.0 -0.1 -0.5 -0.1 -0.1 0.5 -0.1 -0.1 0.3 0.3 0.3 -0.2 -0.2 0.1 0.1 0.4 0.5 0.6 0.1 -0.0
Financial situation satisfaction 0.2 0.2 1.1 -0.0 0.2 0.3 0.1 0.3 -0.0 0.0 -0.6 -0.4 0.6 0.1 -0.0 -0.0 0.3 0.1 -0.6 -0.2 0.3 0.6 -0.1 -0.2 -0.2 0.6 0.8 -0.1 0.0 0.2 -0.1 0.7 1.0 0.9 -0.1 1.0 0.8 0.1 0.7 0.9
Tinnitus: Yes, now most or all of the time 1.1 1.3 4.2 1.0 1.0 -1.0 -1.5 -0.3 0.6 0.7 0.2 0.3 1.4 1.9 1.2 1.5 -0.1 0.4 0.7 1.2 -0.8 1.3 0.8 0.9 0.9 1.3 0.4 0.3 1.5 1.6 1.2 -0.1 0.2 2.0 1.2 1.7 1.6 1.4 1.7 1.6
Commuting to job workplace: Public transport 0.4 0.5 3.4 -0.2 -0.4 0.4 1.1 0.4 -1.2 -1.2 -1.8 -0.4 -0.4 -0.6 -1.2 -1.1 -0.3 0.5 -0.7 -0.6 0.8 -0.8 -0.1 -0.8 -0.8 0.3 0.6 -0.9 -0.7 -0.5 -0.7 -0.0 -0.1 -0.3 -0.7 -0.2 -0.9 -0.3 -0.5 -0.2
Eye problems/disorders: Glaucoma 1.6 1.9 4.0 1.8 1.7 -0.4 -0.2 0.7 1.1 0.4 0.6 0.5 1.6 1.8 1.5 1.7 1.2 1.3 1.8 1.6 -1.4 2.0 1.2 1.6 1.6 1.8 1.1 1.3 1.2 1.5 1.8 0.4 0.7 1.4 1.9 1.5 0.2 1.7 1.3 1.8
Medication: Blood pressure 7.3 13.8 28.8 4.6 4.8 -0.3 -1.0 0.3 3.8 0.9 2.9 4.4 4.6 4.7 5.4 5.2 1.8 2.4 4.8 5.1 -5.0 4.7 4.2 5.2 5.2 3.4 0.0 4.9 3.6 3.7 4.5 -1.3 -0.9 2.8 4.9 1.5 0.3 2.9 2.1 4.1
Pain type(s) experienced in last month: Hip pain 1.9 2.4 12.7 -1.1 -0.8 2.5 3.6 1.9 -2.3 -1.0 -1.9 -2.1 -1.0 -1.1 -1.7 -1.6 -0.2 1.0 -2.0 -1.6 2.1 -0.9 -0.2 -1.7 -1.7 -0.1 1.6 -1.9 -1.5 -1.5 -1.5 1.6 1.6 -1.1 -1.1 -0.4 -1.3 -0.5 -0.7 -0.5
Supplements: Fish oil (including cod liver oil) 0.6 0.8 5.1 1.2 0.2 -0.3 0.0 -0.3 -0.8 -1.2 -0.0 -0.3 0.4 0.7 0.5 0.3 -0.4 -0.6 1.0 0.6 -0.5 0.8 -0.3 0.4 0.4 -0.3 -0.5 0.3 1.8 1.4 1.2 0.3 0.6 1.3 1.0 1.5 2.2 1.7 1.7 0.5
High cholesterol (Self-reported) 0.5 0.9 2.6 -0.7 -0.9 -1.2 0.3 1.0 -0.8 -0.4 -0.3 -0.9 -0.7 -1.1 -0.9 -1.0 1.4 -0.4 -1.5 -1.2 1.2 -1.4 -1.2 -1.3 -1.3 0.8 0.5 -1.2 -1.4 -0.9 -1.4 -0.2 -0.1 -0.1 -1.6 -0.1 -0.7 -1.2 -0.7 -0.0
Medication: Bendroflumethiazide 8.3 12.5 24.8 4.1 3.8 -2.7 -3.3 -1.0 4.4 2.2 3.1 3.8 3.9 3.6 4.8 4.6 2.2 0.5 5.0 4.8 -4.7 3.8 2.4 4.6 4.6 2.1 -1.2 4.5 4.1 4.3 4.7 -1.9 -1.3 3.1 4.3 2.4 2.4 3.1 2.7 3.4
Medication: Paracetamol 0.6 1.0 3.2 -0.5 -0.7 -0.9 0.7 1.4 -0.7 -0.6 -0.6 -0.7 -0.9 -0.4 -0.7 -0.6 0.0 0.7 -1.5 -0.9 1.2 -1.8 -0.2 -1.2 -1.2 1.2 1.0 -1.2 -1.7 -1.1 -1.5 -0.6 -0.7 -0.5 -1.8 -0.5 -0.6 -1.3 -1.2 -0.5
Medication: Lisinopril 0.7 1.0 6.1 -0.3 0.8 -0.8 -0.7 2.5 1.2 -0.8 0.0 0.4 1.1 0.3 0.3 0.5 0.9 0.7 0.8 0.9 -1.1 1.2 0.8 1.2 1.2 1.0 0.9 1.0 0.8 1.0 1.5 0.4 0.2 0.7 1.4 0.7 -0.1 1.5 0.4 1.7
Medication: Atorvastatin 0.7 0.9 3.5 1.3 0.9 0.1 -0.1 1.2 -0.4 -0.9 -0.4 0.1 1.3 1.5 0.8 0.4 -0.9 1.0 0.3 0.8 -0.4 0.4 0.6 0.5 0.5 1.9 1.1 0.2 0.9 1.3 0.7 -0.5 0.2 1.5 0.6 1.6 1.3 0.9 1.3 1.3
Illnesses of father: High blood pressure 0.9 1.2 2.9 1.7 1.5 0.5 0.2 0.4 0.3 -0.9 0.5 1.3 1.6 1.5 1.4 1.1 0.5 0.8 1.0 1.5 -1.3 1.3 1.3 1.4 1.4 1.1 0.1 1.4 1.1 1.1 1.1 -0.6 -0.4 0.9 1.3 0.5 0.3 0.5 0.7 1.5
Alcohol drinker status: Never 0.5 0.6 3.1 0.3 0.8 1.8 0.8 1.0 -1.0 -0.2 -1.4 -0.1 0.8 1.0 0.5 0.5 0.9 1.2 -0.5 0.0 -0.1 0.7 1.2 0.4 0.4 0.2 1.0 0.1 0.2 0.3 0.0 0.7 1.2 0.7 0.4 0.7 0.0 0.1 1.0 0.7
Ever smoked 0.3 0.5 2.4 0.5 -0.2 -1.2 -0.7 0.6 -0.1 -1.6 0.1 0.1 0.2 -0.2 0.3 0.1 0.8 -1.2 0.7 0.3 -0.6 1.0 -0.9 0.4 0.4 0.3 -0.9 0.4 1.0 0.7 1.1 0.5 0.2 0.2 0.8 0.5 1.1 1.3 0.5 0.2
Basal metabolic rate 7.5 41.8 89.7 -6.9 -7.4 2.1 5.4 2.9 -6.5 -3.9 -6.5 -7.8 -7.9 -7.2 -8.7 -8.3 -3.6 -1.2 -7.9 -8.5 8.9 -7.2 -4.8 -8.7 -8.7 -1.2 2.5 -9.5 -7.4 -7.4 -7.4 2.5 1.2 -7.5 -7.3 -4.3 -6.1 -3.7 -5.7 -6.9
Leg fat percentage (left) 2.2 8.0 17.0 4.1 2.9 -0.7 -0.2 -0.3 1.7 0.1 1.6 2.2 3.6 3.6 3.7 3.8 0.8 1.0 4.0 3.4 -3.4 3.7 2.3 3.4 3.4 2.9 0.4 3.0 3.3 3.5 3.8 -0.1 0.5 3.3 3.9 2.6 1.8 3.5 2.8 3.7
Arm fat-free mass (left) 6.8 34.3 78.0 -6.0 -6.9 2.1 5.2 2.9 -6.2 -3.7 -6.5 -7.5 -7.0 -6.5 -8.0 -7.6 -3.2 -1.3 -7.1 -7.8 8.2 -6.2 -4.6 -8.0 -8.0 -1.3 2.5 -8.8 -6.4 -6.4 -6.4 3.0 1.9 -6.4 -6.3 -3.4 -5.2 -2.8 -4.6 -6.0
Number of operations (self-reported) 1.2 1.7 5.6 -0.9 -1.2 1.2 2.3 2.2 -2.4 -2.0 -1.9 -1.7 -1.1 -1.0 -1.6 -1.6 0.1 -0.3 -1.4 -1.5 1.6 -0.6 -0.8 -1.5 -1.5 -1.0 0.6 -1.9 -0.8 -1.1 -1.1 1.6 1.3 -0.6 -0.6 -0.3 -1.0 0.0 -0.2 -0.5
Average weekly beer plus cider intake 3.2 4.6 10.3 -2.4 -2.5 1.9 3.1 1.0 -3.2 -1.6 -2.1 -2.7 -2.2 -2.5 -2.8 -2.8 -0.9 -1.6 -2.5 -2.6 2.7 -2.0 -2.1 -2.8 -2.8 -2.5 -0.4 -2.7 -1.5 -2.3 -2.1 2.1 1.3 -1.6 -1.9 -1.3 -0.7 -0.7 -1.1 -1.8
Irritability 0.4 0.6 4.3 -0.8 0.3 -1.3 -1.0 -1.4 1.3 2.1 1.6 0.9 0.1 -0.6 0.3 0.4 -0.0 0.7 -0.6 0.2 0.1 -0.5 1.2 0.1 0.1 0.2 0.3 0.2 -0.6 -0.3 -0.6 -1.1 -1.2 0.2 -0.6 -0.6 -0.4 -1.1 -0.6 0.1
Risk taking 0.6 0.9 5.5 0.5 -0.4 1.1 0.6 1.0 -1.7 -2.3 -1.7 -1.4 -0.3 0.0 -0.4 -0.5 0.3 -0.6 0.4 -0.3 0.7 1.0 -0.7 -0.7 -0.7 -0.4 0.2 -0.9 0.7 0.4 0.5 1.8 1.8 0.4 0.7 1.1 0.8 1.5 1.2 0.1
Ever had prostate specific antigen (PSA) test 0.4 0.4 2.0 0.3 0.8 0.2 -0.4 -0.1 0.9 1.1 0.7 0.6 0.5 1.2 0.7 0.8 1.4 0.6 0.3 0.5 -0.7 0.7 0.7 0.9 0.9 0.6 0.7 0.9 0.0 0.2 0.3 0.1 0.4 0.2 0.6 0.2 -1.0 0.1 0.3 0.5
Fractured/broken bones in last 5 years 2.3 3.0 5.4 -1.6 -2.2 0.8 1.5 1.1 -1.8 -1.4 -2.2 -2.2 -1.8 -1.6 -2.1 -2.0 -0.0 -1.0 -1.8 -2.2 2.3 -1.5 -1.7 -2.3 -2.3 -1.5 0.0 -2.2 -1.5 -2.2 -1.7 2.0 1.1 -1.9 -1.2 -1.5 -2.0 -0.5 -1.2 -1.6
Age started oral contraceptive pill 1.0 1.3 6.0 -0.2 -0.1 1.8 1.1 1.1 -2.0 -1.9 -1.5 -1.5 -0.1 0.2 -0.3 -0.5 -1.6 -0.2 -0.5 -0.6 0.6 0.8 -0.3 -0.5 -0.5 -1.5 0.7 -0.3 0.6 0.4 0.2 2.2 2.4 0.8 0.4 1.5 1.6 1.1 1.6 0.3
Diastolic blood pressure, automated reading 3.1 9.5 21.0 4.3 3.4 -1.4 -1.5 -1.0 2.9 1.7 2.9 3.7 3.7 4.1 4.6 4.4 0.6 1.2 3.7 4.1 -4.0 3.1 2.8 4.1 4.1 2.7 -0.9 3.8 3.2 3.4 3.5 -2.2 -1.6 3.2 3.4 1.5 1.8 1.8 2.0 3.3
Ever depressed for a whole week 0.2 0.3 2.3 0.2 0.3 0.5 0.4 1.1 -0.1 -0.6 -1.1 -0.1 0.5 0.2 -0.2 0.2 0.3 1.0 -0.4 0.1 0.2 0.1 0.5 -0.1 -0.1 1.5 1.2 -0.4 -0.2 0.1 -0.0 0.1 0.2 -0.0 -0.0 0.4 -0.5 0.3 0.2 0.2
Unable to work because of sickness or disability 0.6 0.8 3.5 0.4 -0.1 1.1 1.6 1.4 -1.2 -1.9 -1.4 -0.8 0.6 0.2 0.2 0.2 0.3 -0.3 0.2 0.1 -0.0 1.0 -0.4 0.0 0.0 -0.2 -0.0 -0.2 1.0 0.5 0.7 1.5 1.3 1.0 1.1 0.7 0.2 1.5 1.1 0.9
Commuting to job workplace: Cycle 1.9 2.3 7.7 -0.9 -1.1 2.1 2.3 2.6 -2.8 -2.4 -1.8 -1.9 -1.2 -0.9 -1.6 -1.7 -1.6 0.9 -1.8 -1.6 1.9 -1.5 -0.2 -1.7 -1.7 0.0 1.5 -1.8 -1.3 -1.3 -1.6 0.9 1.1 -1.0 -1.4 -0.2 -0.8 -0.5 -0.4 -1.1
Myopia 0.4 0.5 3.1 0.1 0.6 1.3 0.7 1.2 -0.7 -1.2 -0.7 -0.5 0.5 0.2 -0.4 -0.3 -0.7 1.2 -0.1 -0.1 0.3 0.6 0.8 0.0 0.0 0.8 1.7 -0.1 -0.3 0.1 0.0 1.0 1.3 0.6 0.2 0.9 0.1 0.4 0.5 0.8
Vascular/heart problems diagnosed by doctor 6.9 18.9 34.3 -5.5 -5.6 -0.1 1.0 -1.0 -3.4 -0.7 -2.1 -4.1 -5.8 -5.6 -5.5 -5.4 -1.8 -2.9 -5.0 -5.7 5.3 -5.9 -4.6 -5.8 -5.8 -4.4 -1.1 -5.4 -4.6 -5.1 -5.3 1.0 -0.2 -4.6 -5.5 -3.7 -2.5 -3.8 -4.0 -5.3
Cholesterol lowering medication 0.6 0.9 5.9 -0.6 -0.7 -0.7 1.0 1.0 -0.2 -0.7 -0.4 -0.5 -0.2 -0.5 -0.4 -0.4 1.7 -0.3 -1.3 -0.9 0.7 -0.9 -0.6 -0.8 -0.8 0.4 0.4 -0.7 -1.6 -1.6 -1.4 0.5 0.0 -0.6 -1.0 -1.3 -2.4 -1.1 -1.4 0.3
Medication: Omeprazole (e.g. Zanprol) 3.2 3.9 9.3 1.7 3.0 0.5 0.5 -0.0 1.3 0.7 1.5 2.7 2.7 2.0 2.2 2.3 1.2 2.1 2.1 2.8 -2.6 2.3 3.0 2.9 2.9 1.8 0.5 2.8 1.9 2.1 2.2 -1.4 -0.8 1.5 2.4 1.0 0.6 1.1 1.2 2.4
Pain experienced in last month 0.3 0.6 4.3 -0.6 -0.6 0.2 -0.8 1.4 -1.2 -2.1 -0.4 -0.7 -0.3 -0.5 -0.7 -0.9 -0.7 -0.8 -0.1 -0.4 0.2 0.1 -1.0 -0.3 -0.3 -0.7 -0.6 -0.3 0.8 0.5 0.4 0.3 0.5 0.3 0.1 0.8 1.6 0.7 0.8 -0.4
Supplements: Calcium 1.3 1.4 9.2 -0.9 -0.5 2.3 2.1 1.5 -1.2 -0.9 -3.0 -1.1 -0.6 -0.9 -0.9 -1.0 0.1 1.3 -1.1 -0.9 1.5 -0.8 0.2 -1.2 -1.2 -0.7 1.0 -1.6 -0.8 -1.1 -0.9 1.1 0.8 -1.0 -0.5 -0.7 -1.5 0.1 -0.6 -0.3
Basal cell carcinoma (self-reported) 2.4 2.9 6.8 -2.5 -2.2 -1.0 0.6 -1.0 -0.4 0.2 -0.7 -1.6 -2.1 -2.6 -1.9 -1.8 1.5 -1.7 -1.6 -1.9 1.6 -1.9 -2.1 -1.9 -1.9 -1.8 -1.0 -2.0 -1.6 -2.1 -1.8 0.7 -0.3 -2.1 -1.6 -2.0 -1.6 -1.2 -1.8 -2.3
Heart attack/myocardial infarction (self-reported) 2.6 3.4 7.5 1.9 2.4 1.5 0.7 0.5 0.6 1.2 -1.3 0.8 2.5 1.8 1.4 1.7 1.0 1.4 1.8 2.0 -1.5 2.7 1.8 1.8 1.8 1.1 1.4 1.7 2.0 2.3 2.0 0.8 1.8 2.7 2.3 2.7 1.9 1.9 2.7 2.6
Deep venous thrombosis (DVT) (self-reported) 0.8 1.0 3.9 -1.0 -1.4 0.2 0.5 1.2 -1.6 -0.9 -1.3 -2.0 -1.0 -0.8 -1.5 -1.2 -0.9 -1.3 -0.5 -1.2 1.2 -0.5 -1.8 -1.3 -1.3 -0.9 -0.0 -1.4 0.1 -0.3 -0.3 1.2 0.9 -0.2 -0.3 0.2 0.0 0.9 0.3 -0.5
Heart disease (siblings) 0.3 0.3 2.3 0.7 -0.5 0.1 1.3 0.2 -1.5 -0.6 0.5 -0.7 -0.1 0.0 -0.2 -0.4 0.8 -1.3 -0.2 -0.4 0.4 -0.3 -0.8 -0.5 -0.5 -0.3 -0.3 -0.3 -0.2 -0.2 -0.6 0.2 0.4 0.6 -0.5 0.2 0.3 -0.3 0.3 0.0
Alcohol drinker status: Previous 1.8 2.0 5.4 -1.5 -2.3 -0.9 0.3 -0.8 -1.5 -0.0 -1.5 -2.0 -2.1 -1.7 -1.9 -1.6 0.2 -2.1 -0.9 -1.7 1.6 -1.2 -2.3 -1.9 -1.9 -1.6 -0.9 -1.9 -0.5 -1.1 -0.9 1.4 0.6 -1.5 -0.9 -0.7 -0.2 0.3 -0.5 -1.9
Pack years of smoking 1.5 2.2 10.8 -1.1 -1.1 2.0 3.3 0.6 -2.2 -0.9 -2.1 -1.5 -0.9 -1.8 -1.4 -1.4 0.8 -0.3 -1.9 -1.5 1.6 -1.0 -0.8 -1.5 -1.5 -2.4 0.3 -1.5 -1.2 -1.7 -1.6 1.8 1.5 -0.6 -1.1 -0.9 -1.1 -1.0 -0.6 -0.4
Impedance of whole body 0.1 0.7 2.9 -0.1 0.9 0.8 -0.9 -0.2 0.7 0.2 0.8 1.4 0.7 0.4 0.9 1.0 -0.5 0.3 0.6 1.0 -1.3 0.1 0.6 1.2 1.2 -1.6 -1.0 1.7 0.8 0.4 0.4 -0.5 -0.5 0.7 0.6 -0.2 0.9 -0.4 0.5 0.1
Leg fat mass (left) 0.2 0.7 3.5 0.5 -0.4 0.4 1.9 0.8 -1.0 -1.3 -1.2 -1.2 0.0 0.1 -0.5 -0.3 -1.1 0.5 0.3 -0.4 0.6 0.3 0.0 -0.5 -0.5 1.8 1.4 -1.1 -0.0 0.1 0.4 0.9 0.9 -0.2 0.5 0.6 -0.7 1.5 0.2 0.4
Arm predicted mass (left) 7.1 36.1 81.2 -6.2 -7.0 1.9 5.2 2.6 -6.2 -3.3 -6.3 -7.3 -7.3 -6.8 -8.1 -7.8 -3.1 -1.3 -7.3 -8.0 8.3 -6.6 -4.6 -8.2 -8.2 -1.4 2.3 -9.0 -6.8 -6.7 -6.8 2.5 1.4 -6.8 -6.7 -3.8 -5.4 -3.3 -5.1 -6.4