Best TWAS P=2.09e-08 · Best GWAS P=4.36e-09 conditioned to 0.0791
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Testis | NT5C2 | 0.20 | 0.03 | lasso | 8 | 0.08 | 2.8e-04 | -4.9 | -5.5 | 3.3e-08 | 0.86 | 0.05 | 0.90 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | CNNM2 | 0.11 | 0.08 | lasso | 3 | 0.07 | 2.2e-09 | -5.3 | -5.3 | 1.2e-07 | 0.99 | 0.02 | 0.98 | FALSE |
| 3 | YFS | Blood | NT5C2 | 0.13 | 0.10 | bslmm | 382 | 0.11 | 7.3e-35 | -5.7 | -5.6 | 2.1e-08 | 0.94 | 0.01 | 0.99 | TRUE |