Best TWAS P=4.18e-09 · Best GWAS P=1.56e-08 conditioned to 0.00969
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | HAUS8 | 0.16 | 0.02 | lasso | 7 | 0.02 | 4.7e-03 | 4.6 | -5.3 | 1.2e-07 | -0.62 | 0.13 | 0.82 | FALSE |
| 2 | GTEx | Esophagus Muscularis | MYO9B | 0.13 | 0.02 | lasso | 5 | 0.05 | 9.5e-04 | 3.8 | -5.9 | 4.2e-09 | -0.62 | 0.03 | 0.95 | TRUE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | HAUS8 | 0.05 | 0.06 | enet | 12 | 0.06 | 2.9e-12 | 4.6 | -5.3 | 9.7e-08 | -0.57 | 0.35 | 0.64 | FALSE |
| 4 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | HAUS8 | 0.21 | 0.11 | enet | 9 | 0.10 | 6.2e-05 | -5.0 | -5.5 | 3.0e-08 | -0.56 | 0.05 | 0.73 | FALSE |
| 5 | The Cancer Genome Atlas | Stomach Adenocarcinoma | HAUS8 | 0.06 | 0.04 | blup | 55 | 0.04 | 1.0e-03 | 4.5 | -5.6 | 1.7e-08 | -0.64 | 0.04 | 0.35 | FALSE |