TWAS
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chr20:7,419,920-9,648,826
Best TWAS P=2e-09 · Best GWAS P=6.38e-13 conditioned to 0.00104
7.5M
8M
8.5M
9M
9.5M
0
2
4
6
8
10
12
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Ovarian Serous Cystadenocarcinoma
PLCB1
0.23
0.09
lasso
9
0.09
1.7e-06
-6.09
6.0
2.0e-09
-0.55
0.53
0.36
TRUE
1
ROSMAP
Brain Pre-frontal Cortex
PLCB1
0.06
0.01
lasso
3
0.03
7.8e-05
-0.36
5.2
1.9e-07
-0.70
0.01
0.98
TRUE