Best TWAS P=2e-09 · Best GWAS P=6.38e-13 conditioned to 0.00104
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | PLCB1 | 0.06 | 0.01 | lasso | 3 | 0.03 | 7.8e-05 | -0.36 | 5.2 | 1.9e-07 | -0.70 | 0.01 | 0.98 | TRUE |
| 2 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | PLCB1 | 0.23 | 0.09 | lasso | 9 | 0.09 | 1.7e-06 | -6.09 | 6.0 | 2.0e-09 | -0.55 | 0.53 | 0.36 | TRUE |