TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Medication: Blood pressure
:
←
chr20:61,667,526-62,912,463
Best TWAS P=8.71e-09 · Best GWAS P=2.14e-08 conditioned to 1
61.6M
61.8M
62M
62.2M
62.4M
62.6M
62.8M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
CommonMind
Brain Pre-frontal Cortex
ZBTB46
0.11
0.08
lasso
3
0.07
1.2e-08
-5.6
-5.8
8.7e-09
1.00
0.00
1.00
TRUE
1
CommonMind
Brain Pre-frontal Cortex
LIME1
0.04
0.00
bslmm
439
0.01
3.3e-02
-4.3
5.4
8.1e-08
-0.17
0.22
0.18
TRUE
3
ROSMAP
Brain Pre-frontal Cortex
ZBTB46
0.11
0.07
lasso
1
0.06
5.2e-08
-5.6
-5.6
2.1e-08
1.00
0.00
1.00
FALSE