Best TWAS P=8.71e-09 · Best GWAS P=2.14e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | LIME1 | 0.04 | 0.00 | bslmm | 439 | 0.01 | 3.3e-02 | -4.3 | 5.4 | 8.1e-08 | -0.17 | 0.22 | 0.18 | TRUE |
| 2 | CommonMind | Brain Pre-frontal Cortex | ZBTB46 | 0.11 | 0.08 | lasso | 3 | 0.07 | 1.2e-08 | -5.6 | -5.8 | 8.7e-09 | 1.00 | 0.00 | 1.00 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | ZBTB46 | 0.11 | 0.07 | lasso | 1 | 0.06 | 5.2e-08 | -5.6 | -5.6 | 2.1e-08 | 1.00 | 0.00 | 1.00 | FALSE |