[Hub]/) : Traits : Medication for pain relief, constipation, heartburn : ←

chr17:44,788,310-45,285,474

Best TWAS P=1.45e-07 · Best GWAS P=3.68e-07 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Esophagus Gastroesophageal Junction	LRRC37A2	0.38	0.49	enet	19	0.50	1.4e-20	-5.1	-5.3	1.4e-07	0.96	0.01	0.99	TRUE
1	GTEx	Brain Caudate basal ganglia	LRRC37A2	0.44	0.62	enet	34	0.68	1.2e-25	-4.7	-5.2	1.5e-07	0.96	0.01	0.98	FALSE
3	GTEx	Esophagus Muscularis	LRRC37A2	0.31	0.51	enet	22	0.51	4.5e-35	-5.1	-5.2	1.7e-07	0.99	0.01	0.99	FALSE
5	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	WNT3	0.04	0.03	blup	57	0.04	3.2e-05	-5.1	-5.2	1.7e-07	0.95	0.01	0.97	FALSE
4	GTEx	Uterus	LRRC37A2	0.64	0.54	lasso	11	0.56	1.1e-13	-5.1	-5.2	2.1e-07	0.97	0.01	0.98	FALSE
6	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	LRRC37A2	0.28	0.36	lasso	6	0.36	3.3e-16	-5.1	-5.1	3.1e-07	0.98	0.01	0.98	FALSE