Best TWAS P=1.45e-07 · Best GWAS P=3.68e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Caudate basal ganglia | LRRC37A2 | 0.44 | 0.62 | enet | 34 | 0.68 | 1.2e-25 | -4.7 | -5.2 | 1.5e-07 | 0.96 | 0.01 | 0.98 | FALSE |
| 2 | GTEx | Esophagus Gastroesophageal Junction | LRRC37A2 | 0.38 | 0.49 | enet | 19 | 0.50 | 1.4e-20 | -5.1 | -5.3 | 1.4e-07 | 0.96 | 0.01 | 0.99 | TRUE |
| 3 | GTEx | Esophagus Muscularis | LRRC37A2 | 0.31 | 0.51 | enet | 22 | 0.51 | 4.5e-35 | -5.1 | -5.2 | 1.7e-07 | 0.99 | 0.01 | 0.99 | FALSE |
| 4 | GTEx | Uterus | LRRC37A2 | 0.64 | 0.54 | lasso | 11 | 0.56 | 1.1e-13 | -5.1 | -5.2 | 2.1e-07 | 0.97 | 0.01 | 0.98 | FALSE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | WNT3 | 0.04 | 0.03 | blup | 57 | 0.04 | 3.2e-05 | -5.1 | -5.2 | 1.7e-07 | 0.95 | 0.01 | 0.97 | FALSE |
| 6 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | LRRC37A2 | 0.28 | 0.36 | lasso | 6 | 0.36 | 3.3e-16 | -5.1 | -5.1 | 3.1e-07 | 0.98 | 0.01 | 0.98 | FALSE |