TWAS hub - WNT3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Visceral Omentum	0.1970	0.0580	3.6e-06	0.046	NA	0.102	NA	0.078	2.1e-03	NA	6.1e-06	NA	7.3e-05
2	GTEx	Artery Aorta	0.1600	0.0430	3.5e-08	0.225	NA	0.230	NA	0.235	1.3e-12	NA	7.1e-13	NA	3.6e-13
3	GTEx	Artery Coronary	0.1330	0.0570	3.2e-03	0.041	NA	0.007	NA	0.016	1.6e-02	NA	1.8e-01	NA	9.4e-02
4	GTEx	Brain Cerebellar Hemisphere	0.2390	0.1010	2.5e-03	0.022	NA	0.050	NA	0.047	8.9e-02	NA	2.0e-02	NA	2.3e-02
5	GTEx	Brain Cerebellum	0.2260	0.0870	4.2e-04	0.100	NA	0.057	NA	0.065	7.0e-04	NA	9.1e-03	NA	5.5e-03
6	GTEx	Brain Cortex	0.2900	0.1200	1.7e-03	0.171	NA	0.100	NA	0.094	1.8e-05	NA	1.0e-03	NA	1.5e-03
7	GTEx	Brain Hypothalamus	0.3310	0.1110	2.0e-04	0.055	NA	0.206	NA	0.048	2.1e-02	NA	1.4e-05	NA	2.9e-02
8	GTEx	Brain Nucleus accumbens basal ganglia	0.2210	0.0940	2.0e-03	0.080	NA	-0.007	NA	0.008	3.6e-03	NA	5.6e-01	NA	1.9e-01
9	GTEx	Cells Transformed fibroblasts	0.1440	0.0520	3.4e-05	0.038	NA	0.083	NA	0.066	7.3e-04	NA	8.0e-07	NA	1.2e-05
10	GTEx	Colon Transverse	0.1000	0.0430	2.5e-03	0.074	NA	0.087	NA	0.066	2.0e-04	NA	6.4e-05	NA	4.3e-04
11	GTEx	Esophagus Gastroesophageal Junction	0.1480	0.0640	3.0e-03	0.058	NA	0.018	NA	0.046	3.7e-03	NA	7.1e-02	NA	9.0e-03
12	GTEx	Esophagus Muscularis	0.1300	0.0400	4.8e-06	0.129	NA	0.105	NA	0.118	3.0e-08	NA	6.1e-07	NA	1.3e-07
13	GTEx	Heart Atrial Appendage	0.2000	0.0630	3.0e-06	0.147	NA	0.054	NA	0.128	3.8e-07	NA	1.8e-03	NA	2.4e-06
14	GTEx	Lung	0.1515	0.0487	4.1e-07	0.132	NA	0.068	NA	0.110	2.8e-10	NA	6.9e-06	NA	9.9e-09
15	GTEx	Nerve Tibial	0.1540	0.0496	4.8e-07	0.141	NA	0.132	NA	0.138	3.4e-10	NA	1.4e-09	NA	5.4e-10
16	GTEx	Pancreas	0.2080	0.0550	8.3e-07	0.129	NA	0.155	NA	0.142	4.5e-06	NA	4.3e-07	NA	1.5e-06
17	GTEx	Spleen	0.2270	0.0820	2.6e-03	0.070	NA	0.049	NA	0.128	7.2e-03	NA	2.2e-02	NA	3.6e-04
18	GTEx	Stomach	0.0880	0.0400	6.4e-03	0.078	NA	0.029	NA	0.062	1.4e-04	NA	1.6e-02	NA	6.4e-04
19	GTEx	Testis	0.1450	0.0540	1.5e-04	0.096	NA	0.139	NA	0.106	5.0e-05	NA	9.9e-07	NA	1.9e-05
20	GTEx	Thyroid	0.2740	0.0650	8.3e-16	0.315	NA	0.296	NA	0.302	1.2e-24	NA	5.6e-23	NA	1.6e-23
21	METSIM	Adipose	0.0443	0.0164	7.2e-05	0.030	0.029	0.034	0.034	0.039	2.4e-05	2.9e-05	6.4e-06	7.2e-06	1.6e-06
22	YFS	Blood	0.0240	0.0101	1.5e-03	0.015	0.010	0.021	0.014	0.015	5.6e-06	2.6e-04	1.7e-07	1.2e-05	5.4e-06
23	TCGA	Kidney Renal Clear Cell Carcinoma	0.0425	0.0215	8.6e-05	0.033	0.039	0.006	NA	0.026	1.2e-04	3.2e-05	6.4e-02	NA	5.7e-04
24	TCGA	Prostate Adenocarcinoma	0.0575	0.0220	6.2e-10	0.112	0.095	0.104	NA	0.113	8.8e-12	4.0e-10	5.5e-11	NA	7.6e-12
25	TCGA	Thyroid Carcinoma	0.0500	0.0230	2.2e-05	0.049	0.043	0.057	NA	0.058	1.3e-05	4.7e-05	3.1e-06	NA	2.7e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25
Hair/balding pattern: Pattern 4	71.0	172.1	259.2	-3.6	-15.4	-16.1	-8.6	-2.9	-6.1	-7.2	-14.9	-9.4	-15.4	-15.2	-15.4	-15.2	-15.4	-15.5	-15.4	-12.5	-15.7	-15.0	-14.9	-8.6	-0.0	-15.9	-15.8	-15.3
Hair/balding pattern: Pattern 3	40.3	60.0	102.0	-3.4	-8.9	-9.6	-6.3	-2.0	-5.8	-5.4	-8.6	-5.1	-9.0	-8.9	-8.8	-9.0	-8.9	-8.9	-9.4	-5.4	-9.1	-8.8	-8.7	-4.4	1.2	-10.1	-8.8	-8.7
Blood Red Count	33.2	321.0	462.2	8.4	20.5	21.3	13.6	2.2	15.8	11.2	19.0	15.5	20.4	20.2	20.4	21.3	20.5	20.4	20.1	14.9	20.4	18.6	20.1	15.6	-0.2	21.0	21.1	21.5
Relative age of first facial hair	29.9	61.6	114.5	1.4	8.9	10.0	4.5	1.1	4.8	3.4	9.1	5.8	9.0	9.1	8.8	9.1	8.9	8.9	9.5	6.3	9.1	9.1	9.0	5.4	-1.6	10.7	9.7	9.2
Lung FVC	28.1	142.9	243.4	-5.6	-13.5	-14.5	-10.6	-4.5	-7.6	-8.5	-13.6	-7.1	-13.5	-13.2	-13.4	-13.3	-13.6	-13.5	-13.9	-9.5	-13.8	-14.7	-13.6	-7.1	3.0	-15.6	-14.0	-14.1
Sensitivity / hurt feelings	26.5	45.3	89.3	2.0	7.6	8.5	4.4	1.4	4.5	4.1	7.6	3.8	7.6	7.5	7.5	7.7	7.7	7.6	7.6	6.1	7.7	8.0	7.6	4.7	-1.7	9.5	8.2	8.0
Neuroticism (Nagel 2018)	24.8	58.4	126.5	2.0	8.6	9.7	5.3	0.3	5.7	5.1	8.6	3.7	8.6	8.4	8.3	8.8	8.6	8.4	8.9	6.0	8.7	9.5	8.6	4.1	-2.6	11.2	9.4	9.1
Neuroticism	23.1	55.8	121.0	2.5	8.4	9.6	5.2	1.5	5.9	4.4	8.3	3.7	8.4	8.4	8.3	8.8	8.4	8.5	8.5	5.9	8.8	9.1	8.4	3.2	-2.6	11.0	8.8	8.6
Forced expiratory volume in 1-second (FEV1)	22.7	76.5	153.8	-2.8	-9.9	-10.6	-6.7	-1.3	-4.5	-4.8	-10.1	-4.7	-9.9	-9.6	-9.9	-9.9	-9.9	-9.9	-10.1	-7.2	-10.2	-11.5	-9.9	-5.3	2.5	-12.4	-10.5	-10.4
Depressed Affect (Nagel 2018)	22.5	47.3	96.2	2.7	7.8	8.6	4.6	-0.1	5.5	5.0	7.5	3.8	7.8	7.6	7.6	8.0	7.8	7.7	7.9	5.2	7.9	8.0	7.7	4.3	-2.3	9.8	8.3	8.2
Forced vital capacity (FVC), Best measure	22.5	82.4	169.0	-4.4	-10.2	-10.9	-7.4	-1.7	-5.4	-5.8	-10.4	-4.9	-10.1	-9.8	-10.1	-10.0	-10.3	-10.1	-10.7	-6.4	-10.4	-12.0	-10.3	-6.0	2.6	-13.0	-10.7	-10.8
Forced vital capacity (FVC)	22.3	86.0	176.9	-3.6	-10.4	-11.2	-7.2	-1.6	-4.8	-5.2	-10.7	-4.9	-10.4	-10.2	-10.5	-10.4	-10.5	-10.5	-10.9	-7.1	-10.8	-12.5	-10.5	-5.5	3.1	-13.3	-10.9	-10.9
Forced expiratory volume in 1-second (FEV1), Best measure	21.8	69.5	134.6	-3.8	-9.4	-10.0	-7.0	-1.9	-5.0	-5.6	-9.6	-4.6	-9.3	-9.0	-9.4	-9.2	-9.5	-9.3	-9.6	-6.3	-9.6	-10.7	-9.4	-5.6	1.6	-11.6	-9.9	-10.0
Ovarian Cancer	21.6	28.5	43.7	-1.2	-6.2	-6.6	-3.3	-0.7	-4.0	-2.3	-6.3	-4.1	-6.2	-6.3	-6.2	-6.5	-6.1	-6.2	-6.5	-5.0	-6.4	-5.8	-6.1	-3.4	0.1	-6.2	-6.3	-6.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	20.9	44.3	72.1	-1.9	-7.7	-8.1	-5.4	-2.2	-3.6	-4.2	-7.6	-4.2	-7.6	-7.6	-7.7	-7.6	-7.6	-7.7	-7.3	-5.8	-7.9	-8.0	-7.4	-4.8	0.3	-8.5	-7.7	-8.0
Neuroticism score	20.8	43.4	91.6	1.4	7.5	8.2	4.6	1.7	5.4	3.5	7.5	3.6	7.5	7.6	7.4	7.9	7.4	7.5	7.5	5.6	7.7	7.9	7.3	3.1	-1.8	9.6	7.7	7.5
Relative age voice broke	20.6	31.5	57.2	1.6	6.4	7.0	3.1	0.7	3.7	2.9	6.2	4.7	6.5	6.6	6.3	6.7	6.3	6.5	6.5	4.6	6.6	6.4	6.3	4.0	-0.6	7.6	6.8	6.6
Headache pain in last month	20.3	34.9	69.6	2.5	6.8	7.5	4.9	0.6	3.5	4.6	6.2	3.0	6.8	6.8	6.7	6.8	6.8	6.8	6.8	4.7	7.0	6.5	6.3	3.6	-2.6	8.3	6.5	7.3
Mood swings	19.7	35.7	71.6	2.4	6.7	7.4	4.2	0.9	5.2	4.4	6.6	3.5	6.7	6.7	6.7	7.1	6.7	6.8	6.6	4.9	6.9	7.1	6.6	2.9	-1.4	8.5	7.0	7.0
Medication: Paracetamol	17.7	29.4	44.5	2.7	6.2	6.7	4.4	-0.5	3.4	4.2	6.1	3.0	6.2	6.2	6.2	6.5	6.2	6.3	6.6	3.7	6.3	5.9	6.1	3.5	-2.9	6.7	6.3	6.3
Hair/balding pattern: Pattern 2	17.5	22.3	37.2	2.1	5.6	6.0	3.3	0.8	2.6	3.4	5.2	3.7	5.6	5.7	5.5	5.5	5.5	5.6	5.7	3.5	5.8	5.2	5.1	2.5	0.2	6.1	5.2	5.3
Medication: Paracetamol	17.5	27.1	41.0	2.4	6.0	6.4	4.5	0.2	2.9	3.8	6.1	2.9	6.0	6.0	5.8	6.1	6.0	5.9	6.4	3.8	6.0	5.9	6.0	3.4	-2.3	6.3	6.1	6.1
Frequency of tenseness / restlessness in last 2 weeks	17.4	27.0	48.2	3.7	6.0	6.4	4.7	0.3	4.0	3.8	5.1	3.7	6.0	6.1	5.7	6.3	5.9	5.9	5.1	3.1	6.0	6.5	5.6	3.2	-1.4	6.9	6.1	6.0
Mouth/teeth dental problems: Mouth ulcers	15.9	25.3	42.8	1.8	5.5	6.0	4.8	1.2	5.4	3.8	5.7	3.9	5.5	5.4	5.3	5.7	5.5	5.4	5.9	4.1	5.4	5.2	5.4	4.5	-0.8	6.5	5.7	5.8
Waist Hip Ratio (WHR)	14.1	63.6	92.4	3.8	8.9	9.1	7.6	5.0	7.3	5.3	9.0	6.7	8.9	9.0	8.8	9.1	8.8	8.9	9.6	7.4	8.9	7.3	8.8	7.0	0.3	8.6	9.2	9.0
Fed-up feelings	13.8	25.1	40.7	2.8	5.8	6.1	3.7	0.1	5.2	3.4	5.6	3.2	5.8	5.8	5.6	6.2	5.8	5.7	5.9	3.7	5.8	5.2	5.6	2.5	-1.3	6.4	5.8	5.6
Handedness (chirality/laterality): Left-handed	13.4	16.2	39.7	-2.4	-4.6	-5.3	-1.7	-0.3	-1.2	-2.6	-4.2	-1.9	-4.6	-4.5	-4.5	-4.7	-4.7	-4.5	-4.4	-2.8	-4.6	-5.3	-4.3	-2.3	2.6	-6.3	-4.6	-4.8
Irritability	13.0	22.1	45.9	0.3	5.3	5.9	2.8	1.9	3.4	1.8	5.9	2.0	5.3	5.1	5.2	5.3	5.4	5.2	6.0	3.4	5.4	5.2	5.5	2.8	-1.8	6.8	5.8	5.8
Average weekly champagne plus white wine intake	12.7	17.4	26.7	-2.4	-4.9	-4.8	-1.9	0.2	-3.5	-2.2	-4.3	-4.0	-4.9	-4.9	-4.9	-5.2	-4.8	-5.0	-4.8	-2.4	-5.0	-4.9	-4.6	-3.1	-1.3	-4.8	-4.9	-4.8
Peak expiratory flow (PEF)	12.5	29.1	57.2	-0.6	-6.1	-6.6	-3.2	0.2	-2.8	-2.1	-6.3	-3.2	-6.1	-6.0	-6.2	-6.3	-6.1	-6.2	-6.5	-4.9	-6.4	-6.6	-6.2	-3.4	1.4	-7.6	-6.5	-6.5
Worry (Nagel 2018)	12.0	25.3	57.8	-0.2	5.7	6.4	3.7	0.3	3.2	2.3	5.8	2.6	5.7	5.7	5.5	5.9	5.6	5.6	5.5	3.8	5.8	6.5	5.7	3.0	-1.3	7.6	6.2	6.0
Ever unenthusiastic/disinterested for a whole week	11.1	13.5	20.0	2.0	4.2	4.5	2.7	0.6	2.9	2.2	4.1	2.7	4.3	4.3	4.2	4.4	4.2	4.3	4.1	3.8	4.4	4.1	4.2	1.4	1.2	4.3	4.3	4.0
Miserableness	11.1	19.1	35.9	1.4	5.2	5.5	2.0	-0.6	2.3	2.4	4.9	2.4	5.2	5.3	5.1	5.5	5.0	5.2	5.0	4.2	5.3	5.3	4.8	1.4	-1.3	6.0	5.0	4.9
Blood Eosinophil Count	10.9	83.8	134.6	-4.4	-10.6	-11.6	-6.7	-0.6	-5.1	-6.3	-9.6	-6.6	-10.7	-10.7	-10.6	-10.4	-10.6	-10.8	-10.1	-8.2	-10.8	-10.3	-10.5	-6.9	1.4	-11.0	-10.7	-10.8
Mean Putamen Volume	10.4	11.9	16.9	-0.6	3.8	3.9	3.3	3.3	2.8	1.5	3.9	2.7	3.8	3.6	4.0	3.5	4.0	3.9	3.8	3.8	3.9	3.7	3.8	2.2	1.0	4.1	4.0	3.9
Qualifications: CSEs or equivalent	10.1	13.4	18.6	2.0	4.1	4.0	3.2	0.0	3.9	2.4	4.0	3.8	4.1	4.0	4.1	4.1	4.2	4.1	3.5	3.7	4.1	3.2	4.2	3.0	1.2	4.0	4.3	4.3
Sitting height	10.1	72.0	139.2	-4.2	-9.4	-9.8	-6.1	-0.1	-7.4	-3.8	-9.5	-6.9	-9.4	-9.4	-9.5	-10.4	-9.3	-9.5	-9.8	-5.8	-9.6	-10.1	-9.4	-7.1	2.4	-11.8	-10.0	-9.9
Nervous feelings	9.9	18.5	40.7	1.4	4.7	5.4	3.4	-0.4	3.6	2.5	4.8	3.0	4.7	4.9	4.5	5.1	4.5	4.7	4.4	3.4	4.8	5.6	4.8	3.0	-1.6	6.4	5.2	5.0
Time employed in main current job	9.8	11.4	27.1	-2.7	-3.6	-4.0	-2.7	-1.1	-3.9	-2.6	-3.4	-1.8	-3.6	-3.5	-3.7	-3.8	-3.6	-3.7	-3.7	-1.9	-3.8	-3.4	-3.5	-2.1	2.0	-5.2	-3.8	-4.0
Medication for pain relief, constipation, heartburn	9.8	16.7	27.3	-2.8	-4.5	-4.9	-3.4	0.6	-3.0	-3.6	-4.6	-1.9	-4.5	-4.6	-4.6	-4.8	-4.4	-4.6	-5.0	-3.4	-4.6	-4.6	-4.5	-2.4	2.1	-5.2	-4.7	-4.7
Neuroticism (2016)	9.7	13.9	26.5	1.5	4.2	4.4	2.5	0.5	3.1	3.1	4.3	2.4	4.1	3.8	4.0	4.2	4.2	3.9	3.9	3.3	4.2	4.4	4.3	3.0	-0.7	5.2	4.7	4.5
Supplements: Vitamin C	9.6	11.3	17.1	1.1	3.9	4.1	2.8	3.0	2.6	1.6	3.9	2.2	3.9	3.8	3.8	3.6	3.9	3.8	3.8	3.1	3.9	3.5	3.8	2.2	0.2	4.1	3.8	3.9
Hand grip strength (left)	9.4	24.7	62.4	-2.0	-5.4	-6.2	-3.2	-1.1	-4.1	-2.0	-5.2	-3.0	-5.4	-5.5	-5.4	-5.9	-5.4	-5.5	-5.7	-3.9	-5.7	-6.1	-5.3	-2.9	3.0	-7.9	-5.9	-5.7
Qualifications: College or University degree	9.0	28.3	47.8	-1.4	-6.2	-6.3	-2.4	1.5	-2.8	-2.3	-6.0	-4.0	-6.2	-6.3	-6.3	-6.5	-6.1	-6.3	-6.1	-5.1	-6.4	-6.9	-6.0	-3.8	0.2	-6.6	-6.0	-6.0
Primary Biliary Cirrhosis	8.9	12.6	23.2	-1.7	-4.1	-4.3	-1.9	0.2	-2.4	-2.6	-3.8	-2.8	-4.1	-4.1	-3.9	-4.1	-4.1	-4.0	-3.6	-3.4	-4.2	-4.2	-3.7	-2.9	-0.6	-4.8	-3.9	-4.3
Number of live births	8.8	12.5	19.4	0.5	3.9	4.2	2.1	0.7	1.7	1.7	3.9	2.6	4.0	4.1	4.0	4.3	3.9	4.0	4.2	3.2	4.1	3.9	4.0	3.8	-0.9	4.4	4.3	4.3
Alcohol intake frequency.	8.7	20.2	45.3	1.1	5.1	5.9	2.9	0.3	3.0	2.0	4.7	2.1	5.1	5.0	5.3	5.3	5.2	5.2	5.2	3.7	5.4	5.0	5.2	2.4	-1.7	6.7	5.2	5.5
Medication: Ibuprofen (e.g. Nurofen)	8.6	10.9	15.8	2.3	3.8	3.8	2.7	-0.4	2.0	2.6	3.9	2.2	3.9	3.9	3.9	3.9	3.8	4.0	3.3	2.8	4.0	3.5	3.8	2.4	-0.2	3.6	3.7	3.9
Worrier / anxious feelings	8.5	16.1	33.8	0.4	4.4	4.9	3.5	1.3	3.7	2.7	4.5	2.3	4.4	4.6	4.3	4.6	4.3	4.4	4.2	3.7	4.5	5.2	4.3	2.5	-1.1	5.8	4.6	4.5
Guilty feelings	8.5	12.8	22.9	1.5	4.0	4.4	3.4	1.9	3.8	3.2	3.8	2.0	4.0	4.0	3.7	4.1	4.0	3.8	4.2	2.1	4.1	4.0	3.8	1.6	-1.1	4.8	4.1	4.0
Hand grip strength (right)	7.6	20.6	46.3	-2.5	-4.9	-5.5	-3.7	-0.4	-4.2	-2.9	-4.7	-2.9	-5.0	-5.0	-4.9	-5.5	-4.9	-4.9	-4.9	-3.3	-5.2	-5.8	-4.9	-2.9	2.1	-6.8	-5.3	-5.1
Hearing difficulty/problems with background noise	7.4	11.8	20.5	1.5	4.0	4.0	2.3	-0.1	0.7	2.2	3.8	2.7	4.1	4.2	4.0	4.0	3.9	4.1	3.9	2.3	4.1	4.5	4.0	2.7	-0.2	4.1	4.0	3.9
Fractured/broken bones in last 5 years	7.4	9.5	18.0	-0.7	3.6	3.8	0.5	-1.4	0.1	-0.6	3.9	1.8	3.6	3.4	3.6	3.5	3.7	3.6	3.5	2.7	3.6	4.0	3.8	2.0	-0.3	4.2	3.9	3.7
Ever depressed for a whole week	7.4	9.2	16.3	1.7	3.4	3.7	2.7	1.2	1.8	1.7	3.3	1.7	3.5	3.4	3.5	3.5	3.4	3.5	4.0	2.7	3.6	3.3	3.2	2.0	-0.9	3.9	3.3	3.4
Breast Cancer	7.0	16.9	32.4	2.1	4.6	5.0	2.6	1.7	3.0	3.6	4.6	3.0	4.6	4.3	4.2	4.1	4.7	4.3	4.2	4.0	4.5	4.6	4.7	3.5	0.1	5.7	5.2	5.2
Systolic blood pressure, automated reading	7.0	20.4	34.1	3.0	-5.3	-5.2	-0.7	-2.1	4.7	1.2	-5.5	-3.2	-5.3	-5.5	-5.1	-4.2	-5.1	-5.3	-5.1	-5.6	-5.2	-5.8	-4.9	-3.3	-2.8	-3.9	-4.8	-4.7
Vitamin and mineral supplements	7.0	9.5	14.7	-1.1	-3.7	-3.7	-3.0	-1.2	-2.8	-2.6	-3.1	-2.4	-3.7	-3.6	-3.6	-3.8	-3.6	-3.7	-2.8	-3.1	-3.8	-3.0	-3.3	-1.3	-0.9	-3.2	-3.4	-3.6
Medication: Ibuprofen	7.0	8.3	12.6	2.2	3.3	3.3	2.4	-0.3	2.2	2.3	3.6	2.0	3.3	3.4	3.2	3.4	3.2	3.3	2.9	2.5	3.4	3.1	3.3	2.0	-0.5	3.3	3.2	3.4
Impedance of arm (left)	6.9	31.8	57.0	-1.7	-6.8	-6.8	-4.2	-2.7	-0.1	-2.9	-6.5	-3.0	-6.8	-6.6	-6.8	-6.1	-6.8	-6.8	-6.7	-3.5	-6.9	-7.5	-6.5	-3.1	0.6	-7.2	-6.5	-6.7
Frequency of depressed mood in last 2 weeks	6.7	9.4	24.5	2.5	3.5	4.0	2.3	0.3	2.1	2.5	3.0	1.6	3.4	3.3	3.2	3.6	3.6	3.3	2.7	2.1	3.4	3.6	3.4	1.2	-1.4	5.0	3.6	3.7
Loneliness, isolation	6.6	9.1	19.4	0.2	3.5	3.9	0.8	-0.1	2.0	0.7	3.6	1.9	3.5	3.5	3.4	3.5	3.4	3.4	3.8	3.1	3.6	3.6	3.4	1.2	-1.4	4.4	3.4	3.4
Heel T-Score	6.4	51.1	82.6	0.8	-8.3	-9.1	-2.5	0.2	-1.2	-0.7	-8.2	-4.1	-8.3	-8.3	-8.1	-8.3	-8.3	-8.2	-8.7	-8.9	-8.4	-8.9	-8.2	-5.0	2.2	-8.6	-8.6	-8.6
Diverticular disease/diverticulitis (self-reported)	6.4	7.5	14.7	1.0	-3.2	-3.4	-0.2	0.1	0.0	0.7	-3.8	-1.1	-3.2	-3.1	-3.1	-3.2	-3.2	-3.1	-3.7	-1.9	-3.2	-3.2	-3.5	-1.5	1.2	-3.8	-3.5	-3.2
Medication: Blood pressure	6.4	12.1	20.9	0.3	-4.3	-4.2	-0.5	-0.1	1.8	-1.8	-4.0	-2.0	-4.3	-4.5	-4.1	-4.3	-4.1	-4.3	-3.9	-4.6	-4.4	-4.5	-4.0	-1.5	-0.6	-3.3	-3.9	-3.5
Myopia	6.4	9.3	14.6	1.7	-3.7	-3.8	-0.1	-0.0	0.1	0.4	-3.7	-1.9	-3.7	-3.7	-3.6	-3.5	-3.6	-3.7	-3.8	-3.5	-3.7	-3.6	-3.4	-2.1	-0.6	-3.4	-3.4	-3.6
Worry too long after embarrassment	6.1	10.2	23.2	0.8	3.5	3.9	2.6	1.4	2.7	2.4	3.5	1.6	3.5	3.6	3.3	3.6	3.4	3.4	3.8	2.8	3.6	3.9	3.5	1.8	-2.1	4.8	3.7	3.6
Impedance of whole body	5.9	30.1	48.7	-1.4	-6.6	-6.7	-2.9	-1.3	-0.1	-1.8	-6.4	-3.1	-6.6	-6.5	-6.7	-6.0	-6.7	-6.7	-6.5	-3.5	-6.8	-7.0	-6.5	-3.4	0.5	-6.9	-6.7	-6.7
Impedance of arm (right)	5.8	26.9	51.2	-1.3	-6.2	-6.3	-3.3	-2.2	0.1	-2.6	-6.0	-2.4	-6.2	-6.0	-6.2	-5.4	-6.3	-6.2	-6.1	-2.8	-6.3	-7.1	-6.0	-2.8	1.2	-7.2	-6.0	-6.3
Depression (Nagel 2018)	5.7	8.6	24.3	1.3	3.3	3.8	2.5	0.5	2.3	1.9	3.1	0.9	3.3	2.9	3.0	3.2	3.6	3.0	2.8	1.8	3.2	3.4	3.5	1.1	-1.5	4.9	3.8	3.7
Noisy workplace	5.5	6.8	11.3	-0.2	2.7	3.1	2.1	1.7	1.1	1.8	3.3	1.4	2.7	2.5	2.8	2.7	2.9	2.7	3.3	2.7	2.7	2.8	3.0	3.0	-1.0	3.1	3.2	3.4
Age at first live birth	5.5	9.7	17.5	0.4	-3.7	-3.5	-2.1	0.3	-1.4	-0.7	-3.5	-2.6	-3.7	-3.6	-3.7	-3.8	-3.7	-3.7	-3.2	-3.4	-3.8	-4.2	-3.5	-2.3	-0.8	-3.6	-3.5	-3.6
Emphysema/chronic bronchitis	5.5	6.2	16.2	1.5	2.6	3.1	1.6	0.2	0.7	1.1	2.7	0.2	2.6	2.6	2.5	2.8	2.6	2.5	3.2	2.1	2.6	2.9	2.6	2.1	-2.1	4.0	3.2	3.4
Number of full brothers	5.3	6.7	17.1	-0.9	2.9	3.2	0.5	-0.5	0.9	0.1	3.0	1.4	2.8	2.9	3.0	3.0	2.8	3.0	3.7	1.7	3.1	3.5	2.9	1.4	-0.8	4.1	3.1	3.0
Qualifications: A levels/AS levels or equivalent	5.2	11.6	21.0	-2.1	-3.9	-3.7	-1.0	2.5	-1.1	-2.0	-3.4	-3.5	-3.9	-3.8	-3.8	-4.2	-3.9	-3.8	-3.2	-2.5	-3.8	-4.6	-3.8	-4.0	-1.0	-3.8	-3.8	-4.1
Leg pain on walking	5.2	6.5	18.6	1.7	2.8	3.1	2.4	0.5	2.2	1.3	2.9	0.6	2.8	2.7	2.8	2.9	2.9	2.8	3.0	1.4	3.0	3.2	2.8	0.2	-1.6	4.3	2.6	2.8
Ever had bowel cancer screening	5.2	6.1	11.2	0.2	-3.0	-3.1	-1.1	-1.0	-0.4	-0.5	-3.0	-1.6	-3.0	-3.0	-3.0	-2.7	-3.0	-3.0	-3.3	-1.9	-3.1	-2.7	-2.8	-1.2	-0.2	-3.0	-2.6	-3.1
Crohns Disease (2012)	5.0	8.1	15.0	-0.7	-3.1	-3.3	-2.7	-0.6	-3.2	-1.7	-3.4	-1.7	-3.1	-3.1	-3.2	-3.6	-3.0	-3.2	-3.0	-2.9	-3.4	-3.2	-3.2	-1.4	-0.1	-3.9	-3.1	-3.1
Trunk fat percentage	5.0	20.0	42.2	2.9	-5.2	-5.6	-1.6	-1.7	-0.2	-0.0	-5.3	-2.2	-5.2	-5.2	-5.2	-4.7	-5.2	-5.2	-5.5	-4.9	-5.4	-6.5	-4.8	-1.6	0.5	-6.0	-5.0	-5.1
Schizophrenia vs Biploar Disorder	4.9	6.5	11.0	-1.1	-2.9	-3.0	-1.2	0.4	-1.9	-1.3	-2.6	-2.3	-2.9	-3.0	-3.0	-3.3	-2.9	-3.0	-3.3	-1.9	-3.1	-2.6	-2.8	-1.8	-1.0	-3.1	-2.9	-3.0
Financial difficulties in last 2 years	4.9	6.6	13.4	1.1	3.0	2.9	1.3	-0.4	1.0	1.4	2.8	2.2	3.0	3.1	3.0	3.3	2.9	3.1	2.4	3.7	3.1	2.7	2.7	2.2	0.3	2.5	2.7	3.0
Systolic Blood Pressure	4.8	24.3	85.9	5.1	-5.3	-5.2	0.3	-2.8	9.3	2.5	-5.9	-1.5	-5.3	-5.4	-5.3	-3.5	-5.2	-5.4	-5.4	-6.3	-5.3	-6.4	-5.0	-3.1	-2.8	-3.2	-5.0	-4.6
Average weekly fortified wine intake	4.8	5.6	11.5	-1.2	-2.5	-2.4	-1.3	-1.5	-3.4	-1.6	-2.7	-2.8	-2.5	-2.5	-2.4	-2.6	-2.4	-2.5	-2.4	-2.3	-2.5	-1.4	-2.6	-3.1	-1.5	-2.2	-2.7	-2.7
Mouth/teeth dental problems	4.8	7.4	18.3	-1.8	-2.5	-3.1	-3.5	-1.3	-3.1	-2.7	-3.0	-0.5	-2.5	-2.2	-2.4	-2.5	-2.8	-2.4	-3.7	-1.6	-2.4	-3.3	-2.9	-1.8	2.6	-4.3	-3.2	-3.1
Illnesses of father: Heart disease	4.8	6.7	16.9	0.2	2.6	3.2	1.8	-0.5	2.5	1.0	3.0	1.0	2.6	2.5	2.7	2.8	2.7	2.6	3.8	2.0	2.7	2.9	2.8	1.6	-2.4	4.1	3.1	3.1
Medication for cholesterol	4.8	7.2	11.9	0.4	3.3	3.3	-0.0	-0.0	-1.1	2.1	3.0	1.6	3.3	3.4	3.1	3.1	3.2	3.2	3.1	3.5	3.3	3.2	2.9	2.0	0.1	2.8	2.9	3.0
Intelligence (Savage-Jansen 2018)	4.7	14.4	30.7	-0.1	-4.2	-4.4	-2.6	-0.5	-3.4	-2.9	-4.3	-2.9	-4.2	-4.0	-4.2	-4.3	-4.4	-4.1	-4.0	-2.9	-4.2	-5.2	-4.3	-2.2	-0.5	-5.5	-4.7	-4.5
Supplements: Zinc	4.5	4.9	7.2	1.5	2.5	2.6	1.6	0.5	1.8	2.0	2.4	1.8	2.5	2.5	2.4	2.4	2.6	2.5	2.5	1.6	2.5	2.2	2.5	1.9	0.1	2.7	2.5	2.7
Heart disease (siblings)	4.5	5.5	9.5	0.2	2.5	2.7	1.3	-0.3	2.4	1.0	2.1	2.7	2.6	2.8	2.6	3.0	2.4	2.6	2.6	2.4	2.7	3.1	2.1	2.1	0.1	3.1	2.5	2.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	4.4	5.3	14.7	-0.0	2.1	2.8	3.4	3.7	0.8	1.5	2.4	0.2	2.1	1.9	2.0	1.7	2.3	2.0	3.0	1.1	2.0	3.0	2.3	0.7	-2.5	3.8	2.4	2.3
High blood pressure (siblings)	4.2	6.1	10.6	0.0	-3.1	-3.0	-1.3	-1.1	1.0	-0.2	-3.3	-1.2	-3.1	-3.0	-3.0	-2.8	-3.1	-3.0	-2.8	-2.2	-3.1	-2.6	-3.1	-1.2	-0.3	-2.4	-3.0	-2.8
Medication for hormone replacement therapy	4.1	4.6	8.4	-0.9	-2.3	-2.5	-1.0	0.5	-1.8	-1.7	-2.4	-1.9	-2.3	-2.2	-2.2	-2.2	-2.4	-2.2	-2.9	-1.9	-2.2	-2.0	-2.4	-2.6	1.0	-2.5	-2.6	-2.7
Mouth/teeth dental problems: Bleeding gums	4.1	5.3	11.2	0.5	2.6	2.7	1.9	1.1	1.2	1.1	3.0	1.1	2.5	2.2	2.7	2.1	2.8	2.5	3.3	2.3	2.5	2.9	2.8	1.2	-0.3	2.8	2.9	2.8
Eye problems/disorders: Glaucoma	4.1	4.9	11.8	-0.8	2.4	2.7	0.7	1.1	1.4	0.6	3.1	1.5	2.4	2.5	2.6	2.2	2.4	2.6	3.0	1.5	2.6	2.5	2.4	1.4	-0.2	3.4	2.6	2.5
Exposure to tobacco smoke outside home	4.0	5.3	14.5	1.6	2.1	2.8	3.0	0.8	1.9	2.4	2.2	0.1	2.1	2.0	2.2	2.1	2.2	2.2	3.0	1.6	2.4	2.5	2.3	0.8	-2.6	3.8	2.8	2.7
Schizophrenia (2014)	3.9	8.7	15.5	0.7	-3.3	-3.5	-1.2	-1.1	-3.1	0.1	-3.5	-1.6	-3.3	-3.2	-3.4	-3.8	-3.3	-3.3	-3.4	-3.0	-3.4	-2.6	-3.7	-1.7	0.6	-3.9	-3.7	-3.5
High blood pressure	3.9	10.8	27.9	1.8	-3.9	-3.7	0.1	-0.1	4.3	-0.6	-3.6	-1.8	-3.9	-4.0	-3.7	-3.4	-3.7	-3.9	-3.6	-5.3	-3.9	-4.1	-3.4	-1.7	-2.1	-2.3	-3.3	-3.1
Prospective memory result	3.9	4.9	7.9	1.1	2.3	2.1	2.2	2.5	2.8	2.3	2.3	2.1	2.3	2.2	2.3	2.0	2.3	2.3	1.9	1.8	2.2	2.0	2.4	1.7	1.9	2.2	2.5	2.6
Ever highly irritable/argumentative for 2 days	3.8	4.6	8.2	1.8	2.4	2.8	1.5	-0.2	1.4	2.1	2.3	0.8	2.4	2.4	2.2	2.6	2.5	2.3	2.9	0.9	2.4	2.4	2.5	0.2	-1.2	2.8	2.5	2.4
Heart disease (mother)	3.8	4.7	9.0	0.6	2.4	2.6	3.0	1.2	1.2	2.0	2.2	1.0	2.4	2.6	2.4	2.5	2.2	2.5	2.4	2.1	2.5	2.5	2.2	1.5	-0.6	2.4	2.1	2.5
Hypertension (Self-reported)	3.8	10.4	27.1	2.3	-3.7	-3.6	0.5	-0.0	4.4	-0.1	-3.5	-1.9	-3.8	-3.9	-3.7	-3.2	-3.6	-3.8	-3.5	-5.2	-3.8	-3.9	-3.3	-1.8	-2.4	-2.1	-3.1	-3.0
Verbal and Numeric Reasoning (VNR)	3.7	9.0	15.1	-0.6	-3.4	-3.4	-2.2	-0.4	-2.8	-2.8	-3.1	-2.7	-3.4	-3.5	-3.5	-3.9	-3.3	-3.5	-2.5	-2.4	-3.5	-3.8	-3.1	-1.1	-1.2	-3.8	-3.5	-3.2
Hearing difficulty/problems: Yes	3.7	5.6	13.0	0.5	2.8	2.6	0.4	-1.1	-1.2	0.3	2.3	1.9	2.8	2.8	2.9	2.6	2.8	2.9	3.0	2.0	2.9	3.6	2.5	2.0	-0.4	2.5	2.6	2.7
Age at last live birth	3.7	5.4	13.1	0.4	-2.7	-2.5	-0.4	0.9	-1.3	0.3	-2.6	-2.1	-2.8	-2.7	-2.8	-2.7	-2.7	-2.8	-2.4	-2.3	-2.8	-3.6	-2.6	-0.8	-1.6	-2.8	-2.5	-2.4
Breast cancer (self-reported)	3.7	4.4	7.5	-0.8	-2.5	-2.7	-1.5	-1.2	-2.3	-0.6	-2.3	-1.3	-2.5	-2.4	-2.4	-2.4	-2.5	-2.4	-2.6	-1.8	-2.6	-2.0	-2.5	-0.2	0.2	-2.7	-2.4	-2.2
Fluid intelligence score	3.6	7.5	14.7	-0.4	-3.0	-3.2	-2.5	-1.0	-2.8	-2.0	-3.0	-2.5	-3.0	-3.0	-3.1	-3.3	-2.9	-3.1	-2.6	-2.1	-3.1	-3.3	-2.9	-1.4	-1.0	-3.8	-3.2	-3.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	3.6	4.2	6.8	-0.6	-2.4	-2.4	-1.5	-1.5	-1.4	-1.7	-2.3	-1.9	-2.4	-2.3	-2.2	-2.2	-2.5	-2.2	-2.6	-1.5	-2.3	-2.0	-2.4	-1.2	-1.2	-2.2	-2.3	-2.4
Multivitamins +/- minerals	3.5	4.4	6.9	0.8	2.6	2.5	1.8	0.3	2.2	2.0	2.2	1.6	2.5	2.4	2.5	2.6	2.6	2.5	1.6	2.2	2.6	1.8	2.3	0.7	0.9	2.1	2.5	2.5
Chronic bronchitis/emphysema (mother)	3.5	4.1	8.0	0.3	2.2	2.3	2.2	-0.2	0.3	1.4	2.0	1.8	2.2	2.1	2.4	2.4	2.2	2.3	2.2	2.0	2.2	2.8	2.1	2.6	0.3	2.1	2.3	2.5
Commuting to job workplace: Public transport	3.5	4.2	9.3	-0.7	-2.1	-2.5	-2.7	-1.4	-1.3	-1.8	-2.3	-1.0	-2.1	-2.1	-2.0	-2.2	-2.2	-2.0	-2.5	-1.9	-1.9	-2.0	-2.2	-3.0	0.3	-2.2	-2.3	-2.4
Pain experienced in last month	3.5	5.9	16.0	-0.8	-2.5	-2.9	-2.8	-1.3	-1.2	-0.6	-2.6	-0.5	-2.5	-2.6	-2.3	-2.5	-2.5	-2.4	-2.7	-2.0	-2.5	-3.6	-2.6	-1.4	2.5	-4.0	-2.7	-2.7
Medication: Amlodipine	3.4	4.7	12.1	1.7	-2.4	-2.5	-0.1	-1.2	1.2	0.8	-2.7	-1.5	-2.4	-2.4	-2.4	-1.9	-2.4	-2.4	-3.1	-3.5	-2.4	-2.6	-2.3	-1.9	-0.8	-2.0	-2.3	-2.4
Height	3.3	63.0	153.8	-2.7	-8.6	-9.5	-4.7	1.4	-5.1	-3.4	-9.3	-4.4	-8.7	-8.6	-8.8	-9.3	-8.7	-8.8	-10.4	-4.1	-8.9	-11.0	-8.6	-5.1	4.9	-12.4	-9.2	-9.2
Severe depression (siblings)	3.3	3.7	9.4	0.7	2.2	2.4	0.9	-0.2	1.4	1.9	2.0	0.6	2.2	2.0	2.2	2.2	2.3	2.2	1.8	3.1	2.3	2.1	2.0	0.4	-1.2	2.2	2.1	2.2
Age when periods started (menarche)	3.3	7.8	12.4	0.4	3.3	3.5	1.6	0.6	1.6	2.0	3.0	1.8	3.3	3.2	3.1	3.4	3.3	3.1	3.1	3.1	3.2	3.2	3.1	1.9	0.8	3.5	3.3	3.4
Tense / ‘highly strung’	3.3	5.4	13.3	-0.4	2.8	3.1	0.5	-0.2	1.1	-0.2	2.5	1.4	2.8	2.9	2.8	3.0	2.7	2.9	2.3	1.8	2.9	3.1	2.5	1.3	-0.6	3.6	2.6	2.5
Qualifications: O levels/GCSEs or equivalent	3.3	5.3	11.5	-3.4	-2.6	-2.4	-1.1	1.7	-0.4	-2.3	-2.4	-2.1	-2.6	-2.5	-2.5	-2.8	-2.5	-2.5	-2.1	-1.5	-2.6	-3.0	-2.5	-2.2	-0.8	-2.0	-2.2	-2.6
Smoking Status	3.2	7.6	19.9	-0.6	-3.0	-3.6	0.5	1.6	-1.6	0.2	-3.2	-1.5	-3.0	-2.9	-3.0	-2.8	-3.2	-3.0	-3.6	-2.2	-3.1	-3.8	-3.1	-0.7	1.6	-4.5	-3.1	-3.3
Illnesses of father: None of the above (group 1)	3.2	3.9	8.9	0.2	-2.0	-2.6	-1.7	-0.1	-1.1	0.2	-2.5	-0.7	-2.0	-1.8	-1.9	-1.8	-2.2	-1.9	-2.8	-1.6	-1.9	-2.4	-2.4	-1.2	2.2	-3.0	-2.6	-2.5
LDL Cholesterol	3.1	4.9	10.5	1.2	2.5	2.5	1.5	-0.3	1.4	1.3	2.5	1.1	2.5	2.4	2.7	2.8	2.5	2.6	3.2	0.2	2.6	2.6	2.4	1.5	-1.9	2.9	2.3	2.4
Comparative body size at age 10	3.1	8.6	20.1	3.9	3.2	2.7	3.9	2.3	4.5	3.0	2.4	3.2	3.2	3.3	3.3	3.3	3.0	3.3	2.1	2.7	3.3	1.5	2.7	1.4	1.6	1.8	2.5	2.8
Comparative height size at age 10	3.1	17.0	37.9	-1.6	-4.4	-5.0	-2.6	0.0	-2.5	-1.9	-4.7	-2.9	-4.5	-4.5	-4.5	-4.7	-4.4	-4.5	-4.9	-2.9	-4.5	-5.5	-4.5	-3.6	1.9	-6.2	-5.0	-5.0
Suffer from ‘nerves’	3.1	4.9	16.2	-1.2	2.2	2.8	2.0	0.7	1.4	0.2	2.5	0.6	2.3	2.5	2.2	2.6	2.1	2.3	2.2	1.2	2.3	3.3	2.4	1.6	-1.4	4.0	2.5	2.5
Lupus	3.0	4.5	10.5	0.7	-2.4	-2.7	-2.0	-2.2	-0.4	-1.1	-2.1	-0.9	-2.4	-2.4	-2.5	-2.5	-2.2	-2.5	-2.2	-1.6	-2.8	-2.9	-1.9	-0.2	-1.0	-3.2	-2.3	-2.3
Trunk fat mass	3.0	12.9	31.0	2.6	-4.0	-4.5	-1.0	-1.1	-0.4	0.1	-4.3	-1.6	-4.0	-4.0	-4.0	-3.8	-4.0	-4.0	-4.6	-3.8	-4.2	-5.6	-3.7	-1.2	1.1	-5.3	-3.9	-4.0
Medication: Omeprazole	3.0	3.6	8.0	-2.2	-2.0	-1.5	-2.1	-0.3	-2.3	-2.8	-1.7	-2.5	-1.9	-1.9	-2.0	-1.9	-1.9	-2.0	-1.5	-0.6	-1.9	-1.4	-1.8	-2.6	-1.4	-1.0	-1.8	-2.1
Past tobacco smoking	2.9	5.3	16.0	0.5	2.4	3.0	-0.5	-2.6	0.6	0.0	2.3	0.6	2.4	2.4	2.5	2.3	2.5	2.5	3.1	0.9	2.5	3.0	2.3	0.8	-2.8	4.0	2.3	2.8
Frequency of tiredness / lethargy in last 2 weeks	2.9	4.7	11.2	2.1	2.3	2.6	1.4	-0.3	1.6	2.2	1.8	0.3	2.3	2.3	2.2	2.5	2.2	2.3	1.5	1.8	2.4	2.3	2.3	1.0	-3.1	3.3	2.5	2.7
Glaucoma (self-reported)	2.9	3.4	8.3	-0.2	1.9	2.1	1.5	1.6	2.3	1.1	2.3	1.3	1.9	2.1	2.1	1.9	1.8	2.1	2.3	0.9	2.1	1.9	1.8	0.9	-0.4	2.9	2.1	1.9
Hearing aid user	2.9	3.3	6.6	2.3	1.9	1.9	1.1	-1.0	2.6	1.7	1.4	1.6	1.9	1.8	1.9	2.2	2.0	1.9	1.9	0.6	1.9	1.4	1.7	2.0	-0.5	2.2	1.7	2.2
Diastolic blood pressure, automated reading	2.9	9.0	13.2	0.8	-3.5	-3.3	-1.3	-1.2	0.1	-1.5	-3.6	-3.3	-3.5	-3.6	-3.4	-3.2	-3.4	-3.5	-3.0	-3.4	-3.5	-3.4	-3.4	-2.7	-3.2	-2.3	-3.4	-3.2
Schizophrenia (2018)	2.8	5.8	11.6	1.4	-2.7	-3.0	-0.1	-0.5	-2.1	0.2	-3.3	-0.5	-2.7	-2.4	-2.7	-3.0	-2.8	-2.6	-3.0	-2.1	-2.8	-2.2	-3.3	-1.2	0.4	-3.4	-3.1	-2.9
Major Depression (MDD)	2.8	3.3	10.9	2.4	1.7	1.9	2.6	0.1	3.3	2.5	2.2	1.6	1.3	1.1	1.1	1.7	1.3	1.1	2.0	0.6	1.6	0.9	2.6	2.1	0.1	1.0	2.6	1.7
Vascular/heart problems diagnosed by doctor	2.8	7.7	20.6	-1.6	3.2	3.1	-0.7	-0.2	-4.5	0.2	2.8	1.3	3.2	3.4	3.1	2.8	3.0	3.2	2.9	4.4	3.3	3.6	2.7	1.3	2.0	1.7	2.6	2.4
Frequency of unenthusiasm / disinterest in last 2 weeks	2.7	3.6	7.1	0.7	2.2	2.3	2.7	1.1	1.9	1.3	2.2	0.8	2.1	1.8	1.8	2.0	2.4	1.8	1.3	1.4	1.9	1.8	2.5	1.2	-0.6	2.5	2.6	2.6
Heel bone mineral density (BMD) T-score, automated (left)	2.7	6.2	14.9	1.2	-2.7	-2.9	0.1	-0.2	1.4	1.4	-3.0	-1.2	-2.7	-2.8	-2.7	-2.8	-2.6	-2.7	-3.2	-3.9	-2.8	-2.8	-2.8	-1.8	0.9	-2.6	-3.0	-2.8
Number of incorrect matches in round	2.7	4.5	9.8	-2.0	2.3	2.4	1.2	1.6	-0.3	-1.4	2.6	1.3	2.3	2.2	2.3	2.1	2.4	2.3	1.3	2.4	2.3	3.1	2.3	1.3	1.6	2.8	2.4	2.5
Illness, injury, bereavement, stress in last 2 years	2.7	3.3	5.7	-1.6	-2.1	-2.2	-1.5	0.1	-0.6	-1.3	-2.1	-0.8	-2.1	-1.9	-2.1	-2.1	-2.1	-2.1	-2.4	-2.1	-2.2	-2.1	-2.0	0.0	0.1	-2.0	-2.0	-1.9
Qualifications: nursing, teaching	2.7	4.2	7.8	0.3	-2.4	-2.7	-0.6	1.2	-0.8	-0.2	-2.2	-0.7	-2.4	-2.4	-2.5	-2.5	-2.4	-2.5	-2.6	-1.2	-2.6	-2.6	-2.1	-0.3	1.9	-2.8	-2.1	-2.4
Ever taken oral contraceptive pill	2.7	3.0	5.1	0.3	2.0	2.1	1.5	1.1	-0.4	1.7	2.0	1.0	2.0	2.0	2.1	1.7	2.0	2.1	1.8	2.3	2.1	1.6	2.0	0.9	-0.0	1.4	2.2	1.8
Risk taking	2.7	4.0	11.6	0.0	2.4	1.7	0.8	1.5	-0.2	0.2	1.9	2.9	2.4	2.3	2.4	2.2	2.3	2.4	1.0	2.6	2.3	2.1	1.9	1.9	3.4	0.6	1.8	2.0
Body fat percentage	2.6	10.3	22.8	3.3	-3.7	-4.0	-0.4	-1.2	0.6	0.7	-3.7	-1.5	-3.7	-3.7	-3.6	-3.3	-3.6	-3.7	-3.9	-4.1	-3.9	-4.8	-3.3	-0.5	0.1	-4.1	-3.4	-3.5
Commuting to job workplace: Car/motor vehicle	2.6	3.0	9.7	2.0	1.6	2.0	3.1	1.1	2.4	2.6	1.3	0.4	1.6	1.4	1.5	1.4	1.7	1.5	1.9	0.4	1.5	1.6	1.5	1.1	-1.2	2.2	1.5	2.0
Smoking status: Previous	2.6	3.9	11.8	-0.4	-2.0	-2.7	0.4	1.9	-0.6	0.1	-1.9	-0.3	-2.0	-2.0	-2.1	-2.0	-2.1	-2.1	-2.5	-1.1	-2.2	-2.6	-1.9	-0.4	3.3	-3.4	-1.8	-2.3
Diabetes (father)	2.5	3.1	8.8	0.5	2.0	2.3	0.7	0.8	1.6	0.3	1.6	0.6	2.0	1.8	1.9	1.9	2.0	1.9	2.5	0.8	2.1	1.8	1.7	0.4	-2.0	3.0	1.9	2.1
Impedance of leg (left)	2.5	12.4	20.6	-0.5	-4.3	-4.5	-0.9	-0.1	0.1	0.1	-4.1	-1.7	-4.3	-4.1	-4.4	-3.8	-4.3	-4.4	-4.3	-2.4	-4.4	-3.8	-4.3	-2.1	0.9	-4.4	-4.5	-4.5
Falls in the last year	2.5	3.3	9.0	-1.8	1.9	2.5	-0.9	-1.1	-1.3	-1.0	2.1	-0.7	1.9	1.7	1.7	1.6	2.0	1.7	2.1	1.9	1.8	2.3	2.0	0.5	-2.1	3.0	2.0	2.1
Pain type(s) experienced in last month: Hip pain	2.5	3.1	6.4	-0.5	2.1	2.1	0.9	-0.4	0.7	-0.8	2.1	1.4	2.0	1.9	2.0	1.9	2.1	2.0	2.1	1.7	2.1	2.4	2.2	0.5	-0.1	2.5	2.2	1.7
Impedance of leg (right)	2.4	11.4	18.6	-0.8	-4.2	-4.2	-0.5	0.9	0.4	0.2	-4.0	-2.1	-4.2	-4.0	-4.2	-3.6	-4.3	-4.2	-4.0	-2.3	-4.2	-3.8	-4.3	-1.9	0.1	-3.8	-4.3	-4.2
Medication: Atenolol	2.4	3.0	5.2	1.3	-2.1	-1.8	-0.4	0.0	2.1	0.2	-1.7	-1.3	-2.1	-2.0	-2.1	-2.0	-2.1	-2.0	-1.4	-2.3	-2.0	-2.2	-1.8	-1.5	-1.4	-0.8	-1.8	-1.8
Medication: Bendroflumethiazide	2.4	3.6	6.8	-0.6	-2.2	-2.3	-2.1	-1.9	0.6	-1.3	-2.2	-0.6	-2.2	-2.1	-1.9	-1.7	-2.2	-2.0	-2.4	-2.6	-2.1	-2.3	-2.1	-0.7	-0.3	-2.0	-2.3	-1.9
Medication: Lisinopril	2.4	3.0	5.5	-0.2	-2.1	-2.0	-0.7	-0.6	0.7	-1.4	-2.1	-0.9	-2.0	-1.8	-1.9	-1.7	-2.2	-1.9	-2.0	-1.8	-1.9	-2.3	-2.3	-1.4	0.3	-2.0	-2.2	-2.1
Medication: Omeprazole (e.g. Zanprol)	2.4	2.9	6.6	-1.2	-1.9	-1.6	-1.6	-0.1	-1.9	-1.9	-1.6	-2.3	-1.9	-1.9	-2.0	-1.9	-1.9	-1.9	-1.3	-0.8	-1.9	-1.4	-1.7	-2.6	-0.7	-1.2	-1.7	-2.0
Standing height	2.3	22.4	61.9	-3.1	-4.9	-5.4	-3.1	1.6	-3.2	-2.2	-5.2	-2.5	-4.9	-4.8	-5.0	-5.4	-4.9	-5.0	-5.9	-1.4	-5.0	-6.9	-5.0	-3.5	4.0	-7.9	-5.5	-5.6
Heel bone mineral density (BMD) T-score, automated (right)	2.1	4.7	10.8	1.1	-2.4	-2.6	0.1	-0.1	0.8	0.7	-2.8	-1.1	-2.4	-2.4	-2.4	-2.5	-2.4	-2.4	-2.7	-3.3	-2.5	-2.4	-2.6	-1.6	0.7	-2.4	-2.7	-2.6
Wheeze or whistling in the chest in last year	2.1	3.7	9.9	1.4	1.9	2.1	1.8	1.3	2.0	1.6	2.0	0.4	1.9	1.8	1.8	2.2	1.9	1.8	2.0	0.9	1.9	2.3	1.9	1.8	-1.6	3.1	2.1	2.5
Average weekly red wine intake	2.1	3.0	6.5	-1.4	-1.8	-2.1	-1.9	-0.3	-2.5	-1.5	-1.7	-1.0	-1.8	-1.8	-1.9	-2.2	-1.9	-1.9	-2.2	-0.3	-1.9	-1.3	-1.5	-0.3	1.8	-2.5	-1.6	-1.7
Average weekly beer plus cider intake	2.1	3.0	5.8	1.4	-1.8	-2.2	0.0	-0.9	-0.8	0.2	-2.4	-0.3	-1.8	-1.8	-2.0	-1.4	-1.9	-1.9	-2.3	-2.3	-1.8	-1.6	-2.1	-1.0	0.9	-2.4	-2.2	-2.0
Blood White Count	2.0	14.6	30.8	2.8	4.1	4.2	5.5	4.2	3.4	3.3	3.8	2.2	4.1	3.7	4.1	4.2	4.3	4.0	3.9	3.4	4.0	3.5	4.1	2.2	-0.2	4.0	4.5	4.5
Lung FEV1/FVC ratio	2.0	10.1	21.0	0.7	-3.7	-4.1	-1.6	-0.3	-1.4	-1.0	-3.6	-2.2	-3.7	-3.6	-3.6	-3.8	-3.7	-3.6	-3.0	-4.6	-3.8	-3.1	-3.5	-1.8	-0.2	-3.8	-4.0	-4.2
Ever had hysterectomy (womb removed)	2.0	2.2	4.8	1.4	1.7	1.6	0.2	-0.7	0.3	-0.3	2.2	1.2	1.6	1.3	1.6	1.1	1.9	1.5	2.0	0.8	1.5	1.3	2.1	2.2	0.8	1.4	2.0	2.0
High blood pressure (mother)	2.0	2.8	5.0	0.4	-1.9	-1.8	-2.2	-2.1	-0.1	-1.2	-2.2	-0.9	-1.8	-1.7	-2.0	-1.7	-1.9	-1.9	-2.1	-1.6	-2.0	-1.9	-1.8	-0.3	-1.0	-1.5	-1.9	-1.6
Osteoporosis (self-reported)	2.0	2.5	8.2	1.5	1.7	1.9	0.7	-0.3	1.1	1.3	1.4	1.2	1.7	1.9	1.7	2.1	1.6	1.8	1.5	0.0	1.9	2.2	1.3	0.5	-0.8	2.9	1.5	1.7
Ever smoked	2.0	3.6	13.7	-0.5	-1.9	-2.5	0.6	2.1	-0.9	0.2	-1.9	0.0	-1.9	-1.8	-1.9	-1.7	-2.0	-1.9	-2.8	-0.9	-2.0	-2.3	-1.8	-0.1	2.4	-3.7	-1.9	-2.1
Age started oral contraceptive pill	2.0	2.5	4.8	-0.7	-1.9	-1.7	-1.7	-1.7	-1.5	-1.0	-1.6	-1.5	-1.9	-1.9	-1.8	-1.7	-1.9	-1.8	-1.6	-2.2	-1.8	-1.2	-1.7	-0.8	-0.4	-1.3	-1.6	-1.6
Medication: Ventolin 100micrograms inhaler	1.9	2.4	5.8	0.4	-1.8	-1.5	-1.3	-1.6	0.3	-0.4	-1.6	-1.7	-1.8	-1.9	-1.9	-1.5	-1.7	-1.9	-1.8	-2.4	-1.9	-1.4	-1.6	-0.7	-1.8	-0.6	-1.6	-1.3
Number of operations (self-reported)	1.9	2.8	7.2	1.9	1.7	2.2	1.9	0.7	1.3	1.5	1.6	-0.4	1.7	1.4	1.4	1.7	2.0	1.4	1.9	1.0	1.5	1.6	1.8	-0.0	-1.5	2.7	2.2	1.9
Alcohol usually taken with meals	1.8	3.0	6.3	-1.7	-2.0	-1.9	-1.5	0.4	-1.4	-1.1	-2.0	-1.6	-2.0	-2.0	-2.0	-2.2	-1.9	-2.0	-2.5	-0.2	-2.0	-1.7	-1.9	-0.8	-0.3	-1.8	-1.8	-1.8
Happiness	1.8	2.2	5.3	0.9	1.6	1.8	-0.2	-0.9	0.5	0.3	1.8	0.8	1.6	1.7	1.7	1.9	1.6	1.7	2.3	1.2	1.8	1.4	1.7	0.7	-1.6	1.9	1.6	1.5
Qualifications: NVQ or HND or HNC or equivalent	1.8	2.2	5.1	1.2	1.7	1.6	1.4	-0.2	1.1	0.9	1.9	0.9	1.7	1.7	1.9	1.8	1.6	1.8	2.3	0.5	1.8	1.2	1.6	0.5	-0.0	1.6	1.6	1.5
Eye problems/disorders: Cataract	1.8	2.0	3.9	-1.1	1.5	1.4	0.7	1.0	0.4	0.2	1.9	0.5	1.5	1.4	1.6	1.4	1.5	1.5	1.9	1.4	1.5	1.9	1.8	1.3	0.1	1.9	2.0	1.6
Blood Platelet Count	1.7	19.4	49.8	4.9	4.8	4.7	5.2	0.8	7.1	4.3	4.6	3.4	4.7	4.6	4.5	5.6	4.8	4.6	4.8	3.5	4.7	2.6	4.6	2.2	0.3	4.0	4.7	4.3
Birth weight of first child	1.7	3.1	6.2	0.2	-1.9	-2.0	0.9	2.4	-0.4	0.9	-2.0	-1.7	-1.9	-1.9	-1.7	-2.1	-1.8	-1.8	-2.5	-0.8	-1.9	-2.5	-1.8	-1.6	0.3	-2.3	-1.8	-2.0
Medication: Blood pressure	1.7	2.9	8.7	2.9	-1.7	-1.7	0.9	0.0	2.9	1.5	-1.8	-0.6	-1.7	-1.7	-1.7	-1.1	-1.7	-1.7	-1.6	-2.4	-1.8	-2.1	-1.5	-0.8	-1.8	-1.2	-1.5	-1.5
Coronary Artery Disease (CAD)	1.6	1.9	10.3	0.4	1.3	1.6	1.3	-0.5	3.2	1.3	1.0	1.0	1.4	1.2	1.3	2.0	1.5	1.2	1.6	-0.2	1.2	1.1	1.3	0.1	-0.6	2.1	1.3	1.2
Age at First Birth	1.5	2.1	4.0	0.3	-1.6	-1.9	-1.2	-0.1	-0.6	-0.6	-1.9	-0.5	-1.6	-1.6	-1.5	-1.6	-1.6	-1.5	-1.9	-0.9	-1.6	-1.6	-1.9	-0.8	1.3	-2.0	-1.8	-1.5
Stomach or abdominal pain in last month	1.5	1.9	8.4	2.9	1.1	1.4	1.4	0.1	1.7	2.9	0.7	0.2	1.1	1.2	1.0	1.4	1.1	1.1	1.0	-0.3	1.1	1.4	1.0	0.6	-1.5	2.0	1.0	1.1
Qualifications: None of the above	1.5	3.3	11.2	0.4	2.1	2.2	0.8	-1.2	0.3	0.5	1.6	1.4	2.2	2.2	1.9	2.4	2.1	2.0	1.8	1.3	2.1	3.3	1.8	1.1	0.2	2.5	1.9	2.1
Medication: Lansoprazole	1.5	1.7	4.2	-0.1	-1.6	-1.7	-0.4	1.6	0.3	-0.6	-1.1	-0.9	-1.6	-1.8	-1.5	-1.9	-1.4	-1.6	-0.7	-2.1	-1.8	-1.5	-1.1	-0.3	-0.4	-1.4	-1.2	-1.3
Whole body fat mass	1.5	6.4	17.1	2.9	-2.7	-3.1	-0.2	-0.7	0.1	0.6	-2.9	-1.1	-2.7	-2.8	-2.7	-2.6	-2.7	-2.8	-3.2	-3.1	-2.9	-4.1	-2.4	-0.4	0.7	-3.7	-2.5	-2.7
Chest pain or discomfort	1.5	2.2	11.8	-0.5	-1.7	-1.3	0.1	0.1	0.5	-0.2	-1.2	-2.4	-1.7	-1.8	-1.8	-1.4	-1.6	-1.8	-0.8	-1.2	-1.7	-1.5	-1.4	-1.4	-3.4	-0.3	-1.4	-1.2
Illnesses of father: High blood pressure	1.5	1.9	3.9	1.6	-1.5	-1.6	0.0	-1.1	0.1	-0.0	-2.0	-0.6	-1.5	-1.3	-1.6	-1.2	-1.6	-1.5	-1.6	-1.9	-1.4	-1.5	-1.6	-1.4	-0.2	-1.6	-1.5	-1.4
Crohns Disease (2017)	1.4	3.1	7.3	2.1	-1.8	-2.1	-0.1	-0.2	0.3	1.3	-2.2	-0.6	-1.8	-2.0	-2.1	-2.0	-1.7	-2.1	-1.7	-2.7	-2.1	-2.5	-1.7	-0.8	-0.4	-2.2	-1.7	-1.6
Neck or shoulder pain in last month	1.4	2.0	3.9	-0.3	-1.6	-1.8	-0.7	-0.4	-1.7	-1.2	-1.2	-1.2	-1.6	-1.7	-1.6	-2.0	-1.5	-1.7	-1.6	-0.9	-1.8	-1.1	-1.4	-0.4	-0.5	-1.7	-1.5	-1.6
High cholesterol (Self-reported)	1.4	2.5	4.7	1.3	-1.9	-1.7	-1.1	-1.0	1.1	1.0	-1.4	-1.2	-1.9	-1.9	-2.0	-1.4	-1.8	-2.0	-1.1	-2.2	-2.0	-1.9	-1.7	-0.8	-1.6	-1.3	-1.4	-1.5
Cholesterol lowering medication	1.4	2.1	3.8	-0.9	-1.8	-1.6	-0.2	0.2	0.3	-1.1	-1.3	-1.6	-1.9	-1.9	-1.9	-1.5	-1.8	-1.9	-0.8	-1.9	-1.9	-1.3	-1.5	-0.7	-1.6	-1.0	-1.3	-1.3
Pulse wave Arterial Stiffness index	1.3	1.5	4.2	-0.2	-1.3	-1.2	0.3	1.7	0.2	-0.7	-1.4	-2.0	-1.3	-1.6	-1.2	-1.2	-1.1	-1.4	-1.6	-1.2	-1.2	-1.2	-1.2	-1.7	-1.3	-0.2	-1.0	-1.0
Shortness of breath walking on level ground	1.3	1.5	3.0	-0.2	1.3	1.5	0.6	0.7	1.0	0.1	1.6	0.2	1.3	1.1	1.4	1.4	1.4	1.3	1.5	1.4	1.4	1.1	1.6	0.5	-0.5	1.7	1.7	1.6
Number of full sisters	1.3	1.6	3.0	-0.5	1.6	1.5	0.6	0.2	0.7	0.4	1.2	1.2	1.7	1.7	1.5	1.7	1.6	1.5	1.3	1.0	1.6	1.4	1.2	-0.2	1.3	1.0	1.3	1.2
Alcohol drinker status: Never	1.3	1.5	4.5	0.5	1.3	1.6	0.9	0.6	1.2	1.0	0.7	-0.2	1.4	1.6	1.6	1.8	1.2	1.6	0.9	1.2	1.7	1.6	0.9	-0.4	-1.0	2.1	0.8	1.0
Fasting Glucose	1.2	1.4	3.0	0.7	-1.4	-1.7	0.3	1.0	0.3	-0.5	-1.6	-0.7	-1.4	-1.3	-1.4	-1.0	-1.6	-1.4	-1.6	-0.7	-1.3	-1.4	-1.5	-0.3	0.0	-1.5	-1.3	-1.4
Cardiovascular Disease	1.2	4.1	37.7	3.6	-1.5	-1.2	2.3	-0.0	6.1	2.0	-1.3	-0.1	-1.5	-1.4	-1.3	-0.2	-1.5	-1.4	-1.2	-3.3	-1.4	-2.1	-1.3	-0.9	-2.3	0.1	-1.0	-0.8
Eye problems/disorders: None of the above	1.2	1.4	4.9	-0.1	-1.1	-1.2	-0.2	-1.6	-0.7	-0.8	-1.8	-0.3	-1.1	-1.1	-1.1	-0.7	-1.1	-1.1	-2.0	-0.3	-1.2	-1.2	-1.2	-1.1	0.0	-2.2	-1.4	-1.3
Mean time to correctly identify matches	1.2	2.3	17.1	-0.9	-0.9	-0.3	-1.9	-2.2	-4.1	-1.8	-0.5	-2.3	-0.9	-1.0	-0.9	-1.1	-0.8	-0.9	-0.5	-0.8	-0.7	2.1	-0.7	-1.8	-2.1	1.3	-0.5	-0.5
Mineral and other dietary supplements	1.2	1.6	3.1	0.1	-1.5	-1.4	-1.3	-1.6	-0.5	-1.3	-1.4	-0.7	-1.4	-1.3	-1.3	-1.2	-1.5	-1.3	-1.2	-1.8	-1.4	-1.2	-1.4	-0.6	-1.0	-0.9	-1.5	-1.4
Bipolar Disorder or Schizophrenia	1.1	2.6	5.1	2.0	-1.7	-1.8	0.0	-1.0	-1.8	1.3	-2.3	-0.3	-1.7	-1.5	-1.6	-1.8	-1.8	-1.5	-1.5	-2.0	-1.6	-1.1	-2.2	-0.6	0.1	-2.0	-2.1	-1.8
Alzheimer’s Disease (including proxy)	1.1	1.6	3.5	-0.7	-1.4	-1.6	-1.2	-0.4	-1.1	-1.1	-1.9	-0.7	-1.4	-1.3	-1.3	-1.4	-1.5	-1.3	-1.4	-1.0	-1.3	-1.3	-1.5	-1.0	0.0	-1.7	-1.4	-1.5
Maternal smoking around birth	1.1	1.6	7.5	0.3	0.8	0.3	2.1	2.7	2.2	1.5	1.5	1.0	0.8	0.8	0.9	0.8	0.7	0.9	0.6	1.0	0.9	-0.1	1.2	0.1	2.5	-0.4	1.0	0.5
Waist circumference	1.1	3.9	15.2	3.9	1.8	1.8	3.0	1.4	2.8	2.5	1.8	1.5	1.8	1.8	1.8	1.8	1.9	1.8	1.8	0.2	1.7	0.5	2.1	2.3	-0.2	1.5	2.2	2.0
Hip circumference	1.1	4.5	9.2	2.2	-2.3	-2.5	-0.5	-1.1	-1.0	0.4	-2.6	-1.4	-2.3	-2.2	-2.2	-2.3	-2.3	-2.2	-2.9	-2.8	-2.3	-3.0	-2.0	-1.0	0.2	-3.0	-2.2	-2.3
Pulse rate	1.1	1.8	7.7	-0.0	-1.3	-1.2	-0.9	0.8	-2.8	-0.4	-1.3	-2.2	-1.3	-1.4	-1.3	-1.5	-1.2	-1.3	-1.3	-1.6	-1.2	-0.6	-1.3	-2.0	-0.1	-0.6	-1.1	-1.3
Medication for cholesterol, blood pressure or diabetes	1.1	1.8	7.2	-2.5	1.2	1.2	-0.6	0.2	-2.7	-1.9	1.3	0.5	1.2	1.2	1.1	0.6	1.2	1.1	1.1	1.6	1.1	1.6	1.1	0.6	1.8	0.6	1.1	1.1
Gout (self-reported)	1.1	1.5	4.0	0.1	-1.2	-1.7	-1.3	-1.2	-1.8	-1.1	-0.9	-0.3	-1.2	-1.3	-1.3	-1.2	-1.2	-1.3	-1.3	-0.8	-1.3	-0.7	-1.2	-0.7	1.4	-2.0	-1.2	-1.4
Migraine (self-reported)	1.1	1.3	3.8	-0.9	1.1	1.7	0.7	0.2	-0.7	-0.2	1.3	-0.6	1.1	1.0	0.9	1.0	1.2	1.0	1.5	1.2	1.1	1.3	1.2	-0.3	-1.8	1.9	1.3	1.3
Pulse rate, automated reading	1.1	3.4	12.2	0.3	-1.9	-1.7	-0.8	-0.1	-3.5	0.0	-1.7	-3.1	-1.9	-2.0	-2.0	-2.8	-1.8	-2.0	-1.3	-2.1	-2.0	-1.4	-1.9	-1.3	-1.2	-1.6	-1.8	-1.7
Arm fat percentage (left)	1.1	4.3	12.1	3.2	-2.1	-2.4	-0.4	-2.0	1.1	0.4	-2.2	-0.4	-2.2	-2.2	-2.1	-1.8	-2.1	-2.1	-2.4	-3.0	-2.3	-3.5	-1.8	0.3	0.2	-2.7	-1.8	-1.9
Friendships satisfaction	1.1	1.4	3.6	-0.2	1.4	1.5	0.3	0.5	0.4	-0.4	1.6	0.1	1.4	1.4	1.4	1.6	1.4	1.4	1.9	1.2	1.5	0.9	1.3	-0.4	-0.8	1.3	1.4	1.0
Prostate Cancer	1.0	1.4	6.3	-0.7	-0.9	-1.3	0.1	1.3	0.0	-0.3	-0.4	1.2	-0.9	-0.9	-1.3	-1.0	-1.0	-1.2	-0.8	1.1	-1.4	-1.2	-0.6	1.8	2.5	-2.2	-0.6	-0.7
Chronotype (morning person)	1.0	2.2	10.4	2.5	1.4	1.4	0.8	-1.6	3.2	2.3	0.4	1.5	1.4	1.4	1.4	2.0	1.5	1.4	0.6	-0.1	1.5	0.6	1.1	0.3	-0.4	1.4	1.0	1.1
Other serious medical condition/disability diagnosed by doctor	1.0	1.3	4.8	1.0	1.0	1.4	0.4	-0.4	-0.4	0.6	0.8	-1.5	1.0	0.6	1.0	0.6	1.3	0.9	1.0	0.6	1.0	1.1	1.1	-0.6	-2.2	2.1	1.5	1.4
Bilateral oophorectomy (both ovaries removed)	1.0	1.2	6.6	1.0	1.0	1.0	-0.6	-2.6	-0.2	-0.4	1.1	0.4	1.0	0.9	1.0	1.1	1.0	1.0	1.2	0.3	1.0	1.2	1.2	0.9	-0.9	1.5	1.2	1.1
Medication: Levothyroxine sodium	1.0	1.7	3.7	0.3	1.5	1.9	0.2	-0.9	-0.0	-0.3	0.9	-0.2	1.6	1.7	1.6	1.5	1.4	1.7	1.5	1.1	1.8	1.7	1.4	-0.4	-0.4	1.9	1.4	1.5
Illnesses of siblings	1.0	1.4	3.2	0.5	1.6	1.3	0.0	-0.4	-1.2	0.1	1.8	0.9	1.5	1.4	1.3	1.3	1.6	1.4	1.2	0.5	1.4	0.7	1.7	1.3	0.8	0.3	1.5	1.2
Depression (self-reported)	1.0	1.2	3.5	0.7	1.2	1.3	1.1	-0.1	1.3	0.3	0.8	0.4	1.2	1.4	1.1	1.8	1.0	1.2	0.8	0.3	1.4	1.6	1.1	0.2	-0.2	1.9	1.3	1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.5	5.3	1.7	1.3	1.1	0.3	-1.3	2.3	1.7	1.3	1.1	1.3	1.3	1.1	1.6	1.2	1.2	0.9	0.2	1.2	0.5	1.2	0.8	0.2	1.0	1.1	1.2
Loud music exposure frequency	1.0	1.1	5.7	-2.2	-0.2	-0.3	-2.2	-0.8	-2.4	-1.7	0.1	0.0	-0.2	-0.3	-0.2	-0.7	-0.1	-0.3	-0.4	0.9	-0.4	-1.0	-0.3	0.3	1.3	-1.7	-0.5	-0.3
Smoking status: Current	1.0	1.6	4.9	0.6	-1.4	-1.6	0.7	0.0	-0.4	0.7	-1.6	-0.7	-1.4	-1.2	-1.3	-1.0	-1.5	-1.3	-1.7	-0.7	-1.3	-1.6	-1.5	-0.1	-0.8	-2.2	-1.6	-1.4
Irritable Bowel Disease (IBD)	0.9	2.1	4.6	1.5	-1.3	-1.8	0.4	1.3	0.3	1.6	-1.9	0.4	-1.4	-1.5	-1.5	-1.6	-1.3	-1.5	-1.9	-1.7	-1.6	-1.8	-1.3	-0.2	1.2	-2.1	-1.4	-1.3
Reaction Time	0.9	1.6	9.8	-0.3	0.2	0.7	-0.9	-2.2	-3.1	-0.8	0.7	-1.6	0.2	0.0	0.2	0.1	0.3	0.2	0.6	-0.7	0.4	3.0	0.3	-1.6	-1.7	2.3	0.5	0.4
Bipolar Disorder (2011)	0.9	0.9	5.3	-0.6	0.4	1.0	1.4	1.6	0.9	1.3	0.6	-1.0	0.4	0.3	0.4	0.3	0.5	0.4	1.2	0.0	0.4	0.7	0.5	0.0	-2.3	1.6	0.7	0.7
HDL Cholesterol	0.9	1.5	5.2	2.0	1.1	0.8	0.4	-2.3	2.2	1.6	1.1	1.9	1.1	1.1	1.0	1.4	1.1	1.0	1.0	0.8	1.0	0.4	1.0	1.1	0.9	0.0	0.8	0.8
Rheumatoid Arthritis	0.9	1.3	3.0	-0.2	1.3	1.4	0.8	0.3	-0.1	0.2	1.6	0.6	1.3	1.1	1.2	1.0	1.4	1.2	1.7	-0.2	1.2	1.5	1.5	0.8	-0.2	1.5	1.4	1.4
Triglycerides	0.9	1.4	3.3	0.3	-1.4	-1.4	-0.7	-0.3	0.2	0.4	-1.8	-0.7	-1.3	-1.1	-1.2	-0.7	-1.4	-1.2	-1.5	-1.8	-1.4	-1.6	-1.3	-1.0	0.1	-1.6	-1.5	-1.4
Hair Pigment	0.9	24.6	58.1	-6.2	-5.0	-4.9	-6.6	-0.8	-7.2	-7.6	-4.1	-4.7	-5.0	-5.0	-5.2	-5.9	-4.9	-5.2	-3.7	-4.9	-5.2	-3.6	-4.6	-2.5	-1.3	-4.2	-4.7	-4.9
Pack years adult smoking proportion	0.9	1.3	4.6	1.9	1.1	1.0	0.4	-0.5	1.4	0.4	1.1	1.5	1.1	1.2	1.1	0.9	1.1	1.1	1.6	0.3	1.0	0.3	1.1	2.1	-0.9	0.5	1.3	1.3
Current tobacco smoking	0.9	1.4	5.7	0.6	-1.2	-1.6	0.8	-0.1	-0.7	0.7	-1.5	-0.5	-1.2	-1.0	-1.1	-0.9	-1.4	-1.1	-1.6	-0.6	-1.2	-1.6	-1.4	0.0	-0.4	-2.4	-1.6	-1.3
Hypothyroidism/myxoedema (self-reported)	0.9	1.8	4.5	0.1	1.4	2.0	-0.1	-1.6	-0.6	-0.5	1.1	-0.9	1.4	1.6	1.4	1.4	1.4	1.5	1.4	0.8	1.6	1.7	1.6	-0.1	-1.2	2.1	1.7	1.7
Health satisfaction	0.9	1.2	2.9	1.7	1.2	1.2	0.8	-1.0	0.7	0.1	1.1	0.6	1.2	1.0	1.3	1.4	1.3	1.2	1.4	0.4	1.2	0.9	1.4	0.0	-0.8	1.1	1.4	1.3
Illnesses of siblings: Diabetes	0.9	1.1	3.6	1.0	0.9	1.1	1.4	0.7	1.9	0.2	1.0	0.4	0.9	0.8	0.9	0.8	1.0	0.8	1.4	1.0	0.9	0.8	1.1	0.3	-1.6	1.5	1.2	1.1
Back pain experienced in last month	0.9	1.3	2.8	0.2	-1.2	-1.0	-1.0	-1.1	-1.4	0.2	-1.3	-1.6	-1.2	-1.1	-1.2	-1.0	-1.2	-1.2	-1.4	-0.9	-1.2	-0.2	-1.2	-1.2	-1.7	-0.4	-1.2	-1.1
Number of treatments/medications taken	0.8	1.4	7.6	1.9	0.5	1.0	1.5	-1.0	2.7	1.8	0.5	-0.4	0.5	0.6	0.5	1.1	0.4	0.5	0.7	-0.6	0.6	0.4	0.6	0.1	-2.8	1.6	0.8	0.8
Eye problems/disorders: Diabetes related eye disease	0.8	0.8	3.6	1.2	-0.7	-0.7	0.9	0.9	-0.4	1.9	-0.9	-1.2	-0.7	-0.7	-0.7	-0.9	-0.8	-0.6	-0.2	-1.0	-0.5	-0.4	-1.0	-1.8	-0.4	-0.1	-1.1	-0.7
Medication: Ramipril	0.8	1.0	8.9	1.8	-0.5	-0.4	1.8	1.9	3.0	0.9	-0.3	-0.3	-0.5	-0.8	-0.6	-0.6	-0.3	-0.6	-0.2	-1.0	-0.5	-1.0	-0.1	0.2	-0.5	0.0	-0.1	0.3
Father’s age at death	0.8	1.0	2.6	0.0	-1.0	-1.1	-0.2	1.0	-0.9	0.3	-1.2	-0.1	-1.1	-1.1	-1.2	-1.3	-1.0	-1.2	-1.6	-0.5	-1.2	-1.1	-0.8	-0.1	0.7	-1.6	-1.1	-1.2
Reason for reducing amount of alcohol drunk: Health precaution	0.8	1.0	3.2	0.3	1.1	1.0	0.6	0.6	0.5	1.8	0.7	1.3	1.1	1.2	0.9	0.9	0.9	1.0	0.6	1.2	1.1	1.6	0.6	1.0	0.7	0.9	0.6	0.9
Overall health rating	0.8	1.7	12.3	3.5	0.7	1.0	1.9	-0.5	2.1	1.9	0.5	0.2	0.7	0.7	0.6	1.0	0.8	0.7	0.9	-0.3	0.7	0.8	0.7	0.6	-2.4	1.7	0.9	1.1
Long-standing illness, disability or infirmity	0.8	1.2	4.0	2.0	0.8	1.1	0.8	-1.5	1.4	1.2	1.0	-0.5	0.8	0.7	0.7	0.8	0.9	0.7	1.0	-0.6	0.9	1.1	0.9	-0.6	-1.2	1.9	0.7	1.1
Allergy or Eczema	0.7	1.8	3.5	-0.3	-1.4	-1.2	-1.3	-0.1	-1.1	-0.3	-1.6	-1.8	-1.4	-1.7	-1.6	-1.9	-1.1	-1.6	-1.5	-1.2	-1.6	-1.4	-1.3	-1.6	-1.0	-1.0	-1.4	-1.1
Arm fat percentage (right)	0.7	2.9	9.7	3.1	-1.6	-2.0	0.1	-1.7	1.5	0.5	-1.7	0.0	-1.6	-1.6	-1.5	-1.2	-1.6	-1.6	-1.9	-2.5	-1.8	-3.0	-1.3	0.6	0.6	-2.4	-1.3	-1.5
Mouth/teeth dental problems: Dentures	0.7	1.2	4.0	1.3	-1.1	-0.9	-0.0	-0.2	-0.5	0.3	-1.2	-2.0	-1.1	-1.2	-1.3	-1.0	-1.0	-1.3	-0.7	-2.0	-1.2	-0.4	-1.0	-0.5	-2.0	-0.1	-0.9	-0.9
Asthma	0.7	1.4	4.0	1.9	-1.2	-1.0	0.4	-1.0	1.7	1.3	-1.2	-0.9	-1.2	-1.1	-1.2	-0.4	-1.2	-1.1	-1.5	-2.0	-1.1	-1.0	-1.2	-0.9	-1.6	-0.1	-0.9	-0.7
Pulse wave reflection index	0.7	0.9	4.9	-0.0	0.7	0.9	1.4	1.5	2.2	0.4	0.5	-0.0	0.6	0.4	0.6	0.7	0.8	0.5	0.3	0.7	0.6	0.4	0.8	0.4	-1.8	1.5	0.9	1.1
Medication: Seretide 50 evohaler	0.7	0.8	4.6	1.9	-0.1	-0.6	1.1	0.6	2.1	1.7	0.1	0.9	-0.1	-0.2	-0.1	-0.1	-0.1	-0.2	-0.6	-1.3	-0.3	-0.9	0.1	0.9	1.4	-0.8	0.3	-0.1
Medication: Gliclazide	0.7	0.8	4.0	1.1	0.7	0.8	1.4	1.2	2.0	1.7	0.6	0.3	0.7	0.8	0.6	0.7	0.6	0.7	0.8	0.2	0.8	0.2	0.4	-0.1	-0.5	1.1	0.4	0.5
Mother’s age at death	0.7	0.8	6.3	-1.4	-0.7	-0.6	-1.3	-0.3	-2.5	-1.1	-0.7	-0.7	-0.7	-0.5	-0.5	-0.9	-0.7	-0.5	-1.2	-0.0	-0.6	-0.3	-0.7	-0.2	0.8	-0.6	-0.7	-0.9
Type 2 Diabetes (T2D) (2012)	0.6	0.7	1.8	-0.0	-1.1	-0.6	-0.3	0.6	0.7	0.2	-1.3	-0.4	-1.1	-0.9	-0.8	-0.8	-1.2	-0.9	-0.9	-1.2	-1.0	-1.3	-1.1	-0.1	-0.2	-0.8	-1.2	-0.8
Tanning	0.6	7.5	12.4	-2.7	-2.8	-3.3	-3.3	-1.5	-3.3	-2.9	-2.6	-1.0	-2.8	-2.8	-2.7	-3.1	-2.8	-2.8	-3.0	-2.0	-2.9	-2.6	-2.8	-1.4	2.2	-3.5	-3.1	-3.0
Supplements: Glucosamine	0.6	0.7	6.1	0.2	0.7	0.4	0.9	2.5	-0.6	0.6	1.0	-0.2	0.7	0.5	0.5	0.3	0.7	0.5	0.5	1.3	0.7	0.0	0.8	-0.6	1.7	0.0	0.7	0.4
Lung cancer (father)	0.6	0.7	2.7	-1.1	-0.8	-0.5	-1.6	-0.1	-1.6	-0.9	-0.6	-1.1	-0.7	-0.5	-0.2	-1.0	-0.9	-0.3	-0.1	-0.9	-0.3	-0.5	-0.8	-1.2	-0.5	-0.4	-0.6	-1.0
Blood clot in the leg (DVT)	0.6	0.8	4.8	-2.2	0.5	0.5	-1.3	0.1	-1.7	-1.8	0.4	0.5	0.5	0.5	0.4	0.3	0.5	0.4	0.5	1.8	0.4	0.2	0.3	1.2	0.5	0.2	0.2	0.3
Leg fat percentage (right)	0.6	2.1	10.3	3.2	-1.3	-1.6	1.0	-0.2	1.0	1.6	-1.2	-0.4	-1.3	-1.4	-1.3	-1.1	-1.3	-1.3	-1.4	-2.8	-1.5	-1.8	-1.1	0.8	0.0	-1.4	-1.0	-1.0
Pulse wave peak to peak time	0.6	0.7	3.3	-0.1	0.7	0.6	-0.8	-1.8	-0.6	0.4	0.7	1.6	0.7	1.0	0.6	0.6	0.5	0.7	0.9	0.9	0.6	0.4	0.6	1.2	1.4	-0.5	0.4	0.3
Had major operations	0.6	0.7	3.6	0.5	0.8	1.0	0.6	-0.7	-0.5	0.4	0.3	-0.8	0.7	0.5	0.7	0.8	0.9	0.7	1.2	-0.9	0.7	1.1	0.5	-0.3	-1.9	1.6	0.8	0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	3.4	-0.1	-0.9	-0.9	0.2	0.5	-0.6	-0.0	-1.0	-1.3	-0.9	-0.8	-0.9	-0.8	-0.9	-0.8	-1.3	-0.7	-0.8	-0.6	-0.9	-1.9	0.1	-0.5	-0.9	-1.0
Financial situation satisfaction	0.6	0.8	3.6	-0.9	0.9	0.9	-0.4	0.0	0.6	-1.3	1.1	0.9	0.9	0.9	0.8	1.0	0.9	0.8	0.7	1.9	0.8	0.3	0.9	1.0	0.0	0.6	0.9	0.9
Tinnitus: Yes, now most or all of the time	0.6	0.7	4.7	1.4	0.4	0.7	0.7	-0.8	-0.9	1.2	0.5	-1.0	0.4	0.3	0.4	0.3	0.6	0.3	0.8	0.4	0.4	0.8	0.7	0.2	-2.2	0.8	0.7	0.6
Leg fat percentage (left)	0.6	2.3	11.7	3.4	-1.4	-1.7	0.7	-0.8	0.8	1.4	-1.3	-0.2	-1.4	-1.5	-1.4	-1.3	-1.3	-1.5	-1.6	-2.9	-1.6	-1.8	-1.1	0.7	0.6	-1.8	-1.2	-1.2
Pack years of smoking	0.6	0.9	3.3	1.5	0.9	0.9	0.2	-0.2	1.2	0.2	1.0	1.2	0.9	1.0	0.9	0.6	0.8	0.9	1.4	0.1	0.8	0.2	1.0	1.8	-1.1	0.5	1.2	1.1
BMI	0.5	2.8	18.8	4.3	1.5	1.4	2.3	0.4	0.9	2.8	1.1	1.1	1.5	1.6	1.6	1.7	1.5	1.6	1.0	-0.3	1.6	0.7	1.7	1.0	-0.4	1.2	1.7	1.4
Hypothyroidism (self reported)	0.5	1.2	4.8	0.2	1.1	1.6	-0.5	-2.2	-1.0	-1.0	0.4	-0.9	1.1	1.3	1.0	1.1	1.0	1.1	1.0	0.7	1.2	1.0	1.1	-0.5	-1.2	1.5	1.3	1.2
Medication: Co-codamol	0.5	0.6	2.2	0.9	0.7	0.8	0.5	-0.6	-0.2	-0.2	0.8	0.3	0.8	0.9	0.8	0.7	0.7	0.8	1.1	0.4	0.7	0.4	0.8	1.5	-1.3	0.1	0.8	0.9
Serious illness, injury or assault to yourself	0.5	0.6	3.6	0.2	0.6	0.8	-0.3	-1.6	0.1	0.3	0.6	0.5	0.6	0.6	0.7	0.9	0.7	0.6	0.9	-0.4	0.7	1.2	0.6	0.5	-1.0	1.9	0.6	0.8
Heart attack	0.5	0.7	1.9	-1.2	0.6	0.7	1.0	1.0	0.6	-0.6	0.7	0.9	0.6	0.6	0.7	0.4	0.6	0.6	1.1	0.7	0.6	0.9	0.6	1.4	-0.3	1.2	0.7	0.9
Arm fat mass (right)	0.5	2.0	8.5	2.9	-1.2	-1.6	0.2	-0.7	0.7	0.7	-1.4	-0.1	-1.2	-1.3	-1.2	-1.1	-1.2	-1.2	-1.6	-2.1	-1.4	-2.6	-1.0	0.5	0.8	-2.1	-1.1	-1.1
Breastfed as a baby	0.5	0.6	2.2	-0.1	-0.8	-0.9	-0.7	0.1	-0.4	0.1	-1.0	-0.3	-0.8	-0.7	-0.9	-0.5	-0.9	-0.8	-1.5	-0.5	-0.8	-0.7	-1.0	-0.7	0.7	-0.8	-0.9	-0.8
Number of children fathered	0.5	0.6	2.3	0.8	0.7	0.8	1.5	1.1	0.2	1.2	0.3	-0.1	0.7	0.6	0.9	0.7	0.8	0.8	0.7	-0.1	0.9	1.2	0.4	0.1	-0.8	1.0	0.6	0.6
Medication: Allopurinol	0.5	0.6	4.7	0.3	-0.5	-1.0	-0.7	-0.6	-0.3	-0.8	-0.2	0.3	-0.5	-0.7	-0.8	-0.5	-0.5	-0.8	-0.5	-0.4	-0.7	-0.5	-0.4	-0.6	2.2	-1.6	-0.5	-0.7
Leg fat mass (right)	0.5	1.9	9.3	3.0	-1.2	-1.6	0.7	-0.2	0.2	1.3	-1.2	-0.4	-1.2	-1.3	-1.2	-1.2	-1.1	-1.2	-1.5	-2.5	-1.3	-2.2	-0.9	0.4	0.6	-1.9	-1.0	-1.1
Medication: Aspirin	0.5	0.6	2.0	0.1	0.5	0.6	0.7	1.0	1.4	0.4	0.5	0.4	0.5	0.7	0.8	0.8	0.4	0.8	0.9	1.2	0.7	0.9	0.5	0.6	-1.0	1.2	0.6	0.7
Asthma (self-reported)	0.5	1.0	2.9	1.5	-1.0	-0.9	0.3	-0.9	1.5	0.9	-1.1	-0.8	-1.0	-0.9	-1.0	-0.3	-1.1	-1.0	-1.4	-1.7	-0.9	-0.9	-1.1	-0.9	-1.2	-0.1	-0.8	-0.6
Osteoarthritis (self-reported)	0.5	0.7	5.2	-1.9	-0.4	-0.4	-1.4	-0.7	-1.1	-2.3	0.0	-0.8	-0.4	-0.5	-0.5	-0.8	-0.4	-0.5	0.1	-0.8	-0.5	-0.3	-0.3	-0.2	-0.8	-0.1	-0.1	-0.3
Arm fat mass (left)	0.5	2.2	8.7	3.0	-1.4	-1.7	-0.1	-1.0	0.7	0.7	-1.5	-0.3	-1.4	-1.5	-1.4	-1.3	-1.3	-1.4	-1.7	-2.3	-1.5	-2.8	-1.1	0.3	0.5	-2.0	-1.2	-1.3
Supplements: Fish oil (including cod liver oil)	0.5	0.6	1.3	-0.0	0.9	0.9	1.1	1.0	0.3	0.9	0.6	-0.1	0.9	0.7	0.7	0.8	1.0	0.7	0.7	1.1	0.8	0.7	0.7	0.6	-0.1	0.5	0.9	1.1
Commuting to job workplace: Cycle	0.5	0.6	4.5	-2.1	-0.7	-0.4	-0.4	0.4	-0.5	-0.9	-0.0	-1.7	-0.7	-0.9	-0.7	-0.8	-0.5	-0.8	-0.6	0.1	-0.8	-1.0	-0.1	-0.9	-0.8	-0.1	-0.1	-0.4
Supplements: Calcium	0.5	0.5	1.6	0.5	0.8	0.8	1.0	0.9	0.4	1.3	0.6	0.0	0.8	0.9	0.7	0.9	0.7	0.8	0.8	0.4	0.9	0.3	0.5	-0.6	0.8	0.4	0.7	0.7
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	4.2	-2.1	0.3	0.2	-1.4	0.0	-1.6	-1.6	0.2	0.4	0.3	0.3	0.1	0.1	0.3	0.1	0.2	1.5	0.1	-0.1	0.1	1.0	0.8	-0.2	-0.0	0.1
Leg fat mass (left)	0.5	1.9	9.4	3.1	-1.1	-1.5	0.5	-0.5	0.1	1.2	-1.2	-0.3	-1.2	-1.3	-1.2	-1.3	-1.0	-1.2	-1.5	-2.4	-1.4	-2.1	-0.8	0.3	0.9	-2.0	-1.0	-1.1
Bipolar Disorder (2018)	0.4	0.6	2.7	1.5	0.6	0.9	-0.2	-0.9	-0.3	1.6	0.4	-0.1	0.6	0.6	0.8	0.8	0.6	0.7	1.3	-0.6	0.9	0.9	0.4	-0.2	-0.3	1.1	0.5	0.6
Ulcerative Colitis (UC)	0.4	0.7	4.1	-0.1	-0.4	-0.8	0.7	1.8	0.1	1.0	-0.6	1.2	-0.4	-0.5	-0.5	-0.6	-0.3	-0.5	-1.2	0.1	-0.6	-0.3	-0.3	0.7	2.0	-1.2	-0.3	-0.4
Ulcerative Colitis	0.4	0.6	3.4	-0.8	-0.7	-0.7	0.1	1.8	-0.5	0.1	-0.7	0.2	-0.7	-0.7	-0.7	-1.0	-0.6	-0.8	-1.1	-0.1	-0.9	-0.7	-0.6	0.5	0.9	-1.2	-0.6	-0.4
Type 2 Diabetes (T2D) (2018)	0.4	0.8	5.1	1.4	0.5	0.6	1.6	2.3	1.4	1.5	0.6	-0.5	0.5	0.5	0.6	0.3	0.4	0.6	1.1	-0.1	0.7	0.1	0.3	-0.7	-1.1	0.8	0.4	0.5
Diabetes (mother)	0.4	0.5	4.7	2.2	-0.2	-0.3	0.7	-0.4	0.7	1.9	-0.3	0.3	-0.2	-0.1	-0.2	0.1	-0.3	-0.1	-0.2	-0.4	-0.2	-0.5	-0.1	-0.2	0.7	-0.8	-0.3	-0.5
Townsend deprivation index at recruitment	0.4	0.6	1.8	1.3	0.7	0.4	1.3	-0.1	0.6	0.5	0.6	1.2	0.7	0.9	0.8	0.9	0.6	0.9	-0.1	1.3	0.9	0.5	0.6	0.6	-0.4	0.1	0.5	0.3
Chronic bronchitis/emphysema (father)	0.4	0.5	2.0	-0.6	-0.7	-0.6	0.2	0.5	-0.4	-1.4	-0.2	-1.2	-0.7	-0.8	-0.7	-0.8	-0.7	-0.7	-0.6	-0.3	-0.7	-0.3	-0.3	-0.7	-0.8	0.1	-0.4	-0.7
Had menopause	0.4	0.5	1.8	-1.1	-0.6	-0.6	-0.2	1.3	-0.9	-0.7	-0.3	-1.2	-0.7	-0.8	-0.6	-0.9	-0.5	-0.7	-0.5	-0.9	-0.6	-0.3	-0.5	0.0	-0.9	-0.3	-0.5	-0.2
Pain all over the body in last month	0.4	0.4	3.3	-0.5	0.2	0.4	-0.2	-1.6	-0.7	-0.5	0.6	-0.9	0.2	0.3	0.3	0.4	0.2	0.3	0.4	-0.5	0.4	0.6	0.5	-0.9	-1.8	0.5	0.4	0.1
Medication: Simvastatin	0.4	0.6	5.8	-0.3	-0.8	-0.3	0.4	0.4	1.0	-0.3	-0.5	-0.7	-0.8	-0.8	-0.7	-0.6	-0.6	-0.8	0.0	-1.4	-0.8	-0.5	-0.6	0.1	-2.4	0.5	-0.5	-0.2
Weight	0.4	2.0	7.5	2.0	-1.2	-1.6	-0.0	0.1	-0.4	0.4	-1.5	-0.7	-1.3	-1.3	-1.2	-1.5	-1.2	-1.3	-1.8	-1.9	-1.4	-2.7	-1.1	-0.4	1.1	-2.4	-1.3	-1.4
Trunk fat-free mass	0.4	2.1	6.1	-0.3	1.9	1.4	0.9	2.2	-1.0	0.4	1.4	1.1	1.8	1.8	1.8	1.1	1.8	1.8	1.0	1.7	1.8	0.5	1.6	0.5	2.5	-0.1	1.4	1.4
Trunk predicted mass	0.4	2.1	6.5	-0.3	1.8	1.3	0.8	2.2	-1.0	0.4	1.4	1.1	1.8	1.7	1.8	1.1	1.8	1.8	0.9	1.7	1.8	0.4	1.6	0.5	2.5	-0.2	1.4	1.4
Exposure to tobacco smoke at home	0.4	0.4	2.2	0.1	0.4	0.3	0.1	-0.3	-0.5	0.3	0.1	1.4	0.4	0.7	0.3	0.6	0.2	0.4	-0.0	1.5	0.5	1.1	0.0	1.0	1.4	0.2	0.2	0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	4.4	-1.0	-0.5	-0.7	-0.1	0.8	-2.1	-1.1	-0.8	0.2	-0.5	-0.4	-0.5	-0.7	-0.6	-0.5	-1.1	0.9	-0.5	-1.1	-0.8	-0.7	1.4	-1.6	-0.9	-0.9
Medication: Aspirin	0.4	0.5	1.7	0.3	0.4	0.5	0.8	0.9	1.3	0.6	0.4	0.1	0.4	0.6	0.6	0.7	0.3	0.6	0.9	0.9	0.6	0.8	0.4	0.4	-1.1	1.2	0.5	0.6
Number of self-reported non-cancer illnesses	0.4	0.6	4.9	0.7	0.2	0.5	0.6	-0.6	2.2	0.2	0.1	-1.0	0.2	0.0	0.1	0.3	0.3	0.1	0.3	-0.6	0.2	-0.0	0.1	-0.5	-1.9	1.4	0.5	0.8
Ever had prostate specific antigen (PSA) test	0.4	0.4	2.0	-1.3	-0.3	-0.5	0.2	0.9	-0.9	-1.1	-0.2	-0.5	-0.3	-0.2	-0.2	-0.5	-0.4	-0.2	-0.9	0.6	-0.2	-0.8	-0.1	0.1	0.8	-1.4	-0.0	-0.7
Unable to work because of sickness or disability	0.4	0.5	2.1	0.4	0.6	0.8	-0.5	-1.4	-0.4	-0.6	0.9	-0.7	0.6	0.4	0.4	0.3	0.7	0.4	0.6	0.5	0.6	0.4	0.8	-0.4	-1.1	0.6	0.8	0.8
Heart attack/myocardial infarction (self-reported)	0.4	0.5	1.4	-1.2	0.5	0.6	0.8	0.6	0.6	-0.6	0.6	0.9	0.5	0.5	0.6	0.4	0.5	0.5	1.0	0.7	0.5	0.8	0.5	1.2	-0.4	1.1	0.6	0.7
Alzheimer’s Disease (in mother)	0.3	0.3	2.3	-1.5	-0.3	-0.2	-0.5	-0.2	-0.6	-1.3	-0.5	-0.6	-0.3	-0.2	-0.2	-0.4	-0.3	-0.2	-0.1	-0.1	-0.2	-0.4	-0.2	-0.5	-1.1	-0.3	-0.1	-0.2
Alzheimer’s Disease (in father)	0.3	0.3	1.4	0.5	-0.5	-0.7	-0.2	-0.0	-0.5	-0.1	-0.8	0.0	-0.5	-0.3	-0.6	-0.8	-0.6	-0.5	-0.6	-0.2	-0.5	-0.6	-0.9	-0.1	0.1	-1.2	-0.9	-0.7
Body Mass Index (BMI) (2010)	0.3	0.4	2.5	0.4	0.5	0.6	0.9	1.6	-0.6	-0.1	0.4	0.2	0.5	0.6	0.5	0.4	0.5	0.5	0.2	0.9	0.6	0.2	0.6	0.3	0.3	0.2	0.6	0.6
HbA1C	0.3	0.4	2.0	-0.2	0.2	0.3	1.4	1.0	0.3	1.2	0.0	-0.2	0.2	0.4	0.3	0.4	0.1	0.4	0.6	-0.9	0.4	-0.0	0.0	-0.3	-1.4	0.4	0.2	0.3
Respiratory disease	0.3	0.7	3.8	0.7	-0.9	-0.7	0.5	-0.1	0.9	0.2	-0.8	-1.2	-0.9	-0.9	-1.0	-0.4	-0.9	-0.9	-1.0	-0.8	-0.9	-0.9	-0.9	-0.7	-1.9	-0.3	-0.6	-0.4
Body mass index (BMI)	0.3	1.2	12.0	3.5	0.7	0.5	1.3	-0.6	0.9	1.4	0.6	0.2	0.6	0.5	0.7	0.6	0.8	0.7	0.6	-1.5	0.6	0.1	0.9	1.1	-0.8	0.8	1.0	0.9
Diabetes (self-reported)	0.3	0.5	2.6	1.3	-0.4	-0.3	0.4	1.1	0.7	0.8	-0.1	-0.9	-0.4	-0.4	-0.5	-0.7	-0.4	-0.4	0.6	-0.4	-0.3	-0.4	-0.5	-1.6	-0.9	-0.0	-0.5	-0.5
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	2.0	1.4	0.6	0.5	1.0	1.0	0.4	1.2	-0.0	0.5	0.7	0.6	0.6	0.4	0.7	0.6	0.3	-0.8	0.6	0.3	0.2	0.0	0.5	0.4	0.4	0.8
Illnesses of mother	0.3	0.3	4.3	-0.7	-0.1	-0.5	0.7	2.1	-0.4	-0.3	0.2	-0.2	-0.2	-0.3	-0.1	-0.3	-0.1	-0.2	-0.1	0.3	-0.1	-0.4	-0.2	-0.6	0.4	-0.7	-0.3	-0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	3.6	1.2	0.1	0.4	0.3	0.4	0.9	1.9	-0.0	0.1	0.1	0.3	-0.0	0.6	0.0	0.1	-0.4	-1.1	0.2	-0.1	0.1	-0.1	-0.7	0.5	0.2	0.1
Knee pain experienced in last month	0.3	0.4	2.9	1.7	0.5	0.5	1.2	0.1	0.8	0.6	0.4	-0.1	0.5	0.5	0.2	0.6	0.5	0.3	0.4	-0.4	0.4	0.6	0.5	0.5	-0.8	0.9	0.6	0.5
Diabetes diagnosed by doctor	0.3	0.5	1.6	1.2	-0.6	-0.5	0.1	0.9	0.6	1.0	-0.2	-1.0	-0.6	-0.5	-0.6	-0.8	-0.6	-0.5	0.6	-0.7	-0.4	-0.6	-0.5	-1.3	-0.7	-0.3	-0.6	-0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	2.1	-1.4	0.3	0.3	0.2	0.8	-0.6	-0.9	0.8	-0.0	0.3	0.3	0.2	0.2	0.3	0.2	0.9	0.4	0.2	0.1	0.5	0.8	-0.5	0.3	0.5	0.4
Wears glasses or contact lenses	0.3	0.4	4.7	-0.1	0.3	0.5	0.6	2.2	0.6	-0.1	0.5	-0.1	0.3	0.3	0.3	-0.0	0.3	0.3	0.7	0.3	0.2	0.1	0.4	0.6	-0.4	0.6	0.8	0.5
Alcohol drinker status: Previous	0.3	0.4	2.4	-1.4	-0.4	-0.1	0.5	1.6	-1.0	-0.6	-0.3	-0.7	-0.4	-0.5	-0.4	-0.7	-0.2	-0.5	-0.3	0.3	-0.4	-0.5	-0.3	0.4	-0.2	0.1	-0.2	0.1
Average weekly spirits intake	0.2	0.2	0.6	0.4	0.4	0.4	0.7	-0.7	-0.1	0.4	0.6	0.4	0.4	0.6	0.3	0.6	0.3	0.4	0.7	0.7	0.4	-0.2	0.6	0.5	-0.3	-0.2	0.4	0.3
Angina	0.2	0.3	3.7	0.1	0.0	-0.1	0.8	-0.1	1.9	0.1	0.1	0.8	0.1	0.2	0.3	0.3	-0.0	0.2	0.5	-0.2	0.2	-0.1	-0.0	0.8	-0.3	0.2	-0.2	0.1
Medication: Metformin	0.2	0.3	1.7	0.9	0.3	0.4	0.4	1.0	0.7	0.3	0.6	-0.3	0.3	0.4	0.3	0.3	0.3	0.4	1.3	0.2	0.5	0.0	0.3	0.1	-0.6	0.6	0.3	0.5
Taking other prescription medications	0.2	0.4	2.7	0.6	0.2	0.3	1.6	1.1	1.6	0.5	0.4	-0.1	0.2	0.3	0.2	0.3	0.2	0.3	0.3	-0.3	0.3	0.2	0.3	0.1	-0.5	0.8	0.5	0.3
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	1.0	-0.6	0.2	-0.0	-0.0	-1.0	0.3	-0.6	0.3	0.4	0.3	0.5	0.2	0.5	0.1	0.3	0.2	0.6	0.2	0.3	0.3	0.4	0.7	-0.3	0.3	0.0
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.3	3.1	1.8	0.2	0.1	1.1	0.2	0.9	0.9	0.1	-0.0	0.2	0.1	0.2	0.0	0.2	0.2	0.6	0.1	0.2	0.1	0.1	0.1	0.1	0.0	0.1	0.3
Medication: Cholesterol lowering	0.2	0.3	2.4	1.1	0.1	0.1	0.2	0.1	1.6	1.2	0.1	0.3	0.1	0.1	0.3	0.4	0.1	0.2	0.3	-0.1	0.2	-0.3	0.1	0.4	-1.0	0.4	0.1	0.0
Length of working week for main job	0.2	0.2	2.4	-0.2	-0.2	-0.4	-0.2	-0.5	-1.5	-0.3	0.0	-0.2	-0.2	-0.4	-0.2	-0.7	-0.0	-0.2	-0.2	0.3	-0.3	-0.6	-0.1	-0.3	0.2	-1.0	-0.2	-0.1
Birth weight	0.2	0.4	2.3	1.5	0.3	0.1	1.0	0.5	1.4	1.3	-0.3	0.3	0.3	0.1	0.1	0.1	0.3	0.1	-0.1	0.4	0.1	-0.7	0.2	-0.2	0.7	-0.4	0.3	0.1
Angina (self-reported)	0.2	0.3	4.8	0.1	-0.0	-0.1	0.9	0.4	2.2	0.1	0.2	0.7	-0.0	0.1	0.2	0.2	-0.1	0.2	0.4	-0.3	0.1	-0.2	-0.0	0.8	-0.5	0.3	-0.1	0.1
Arm predicted mass (right)	0.2	0.8	2.7	0.8	1.1	0.8	0.8	1.6	-1.4	0.7	0.9	0.4	1.1	1.0	1.1	0.4	1.1	1.1	0.4	0.6	1.1	0.1	1.1	0.3	1.4	-0.1	0.8	0.8
Family relationship satisfaction	0.2	0.3	3.1	0.6	0.2	0.5	-0.3	0.3	0.6	0.6	0.2	-0.3	0.2	0.3	0.1	0.6	0.2	0.2	0.5	-0.0	0.2	0.3	0.2	-0.2	-1.8	1.0	0.3	0.1
Whole body fat-free mass	0.2	1.0	4.6	0.2	1.2	0.7	0.5	1.7	-1.3	0.1	0.8	0.7	1.2	1.1	1.2	0.5	1.2	1.2	0.5	1.0	1.1	-0.3	1.1	0.3	2.1	-0.8	0.9	0.8
Commuting to job workplace: Walk	0.2	0.2	0.4	0.5	-0.4	-0.4	-0.4	-0.6	0.1	0.0	-0.6	0.4	-0.4	-0.1	-0.2	0.1	-0.6	-0.2	-0.5	0.1	-0.3	-0.1	-0.6	0.2	0.5	-0.2	-0.6	-0.6
Whole body water mass	0.2	1.1	4.9	0.2	1.3	0.8	0.5	1.6	-1.2	0.1	0.9	0.8	1.3	1.2	1.3	0.6	1.3	1.3	0.6	1.1	1.2	-0.2	1.2	0.4	2.2	-0.6	0.9	0.9
Medication: Atorvastatin	0.2	0.3	2.2	1.5	-0.1	-0.2	0.2	-0.6	1.0	1.4	-0.1	-0.0	-0.1	0.0	0.1	0.5	-0.2	0.1	0.8	-0.2	0.0	-0.0	-0.1	0.5	-0.8	-0.1	0.1	0.0
Arm fat-free mass (left)	0.2	0.8	3.6	1.0	1.0	0.6	0.7	1.5	-1.2	0.6	0.8	0.6	1.0	0.9	1.0	0.4	1.1	1.0	0.4	0.4	1.0	-0.1	1.0	0.6	1.9	-0.5	0.8	0.7
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.8	0.4	-0.0	0.0	-0.3	-0.9	-0.2	-0.6	0.4	-0.9	-0.0	-0.1	-0.0	0.1	-0.0	-0.1	-0.0	-0.5	0.0	0.2	0.2	-0.3	-0.4	0.4	0.4	0.1
Leg fat-free mass (left)	0.1	0.4	2.7	0.5	0.3	-0.1	-0.1	0.6	-1.2	-0.3	0.0	0.2	0.3	0.2	0.3	-0.3	0.3	0.3	-0.2	0.2	0.2	-1.4	0.4	0.2	1.6	-1.5	0.1	0.1
Hayfever, allergic rhinitis or eczema	0.1	0.2	0.8	0.5	-0.2	-0.4	-0.4	0.2	-0.4	0.9	-0.7	-0.1	-0.2	-0.4	-0.3	-0.5	-0.0	-0.3	-0.5	-0.7	-0.4	-0.5	-0.4	-0.5	0.7	-0.6	-0.4	-0.1
Leg predicted mass (left)	0.1	0.4	2.6	0.6	0.3	-0.1	-0.2	0.5	-1.3	-0.3	0.0	0.3	0.3	0.2	0.3	-0.3	0.3	0.3	-0.2	0.2	0.2	-1.5	0.4	0.2	1.6	-1.6	0.1	0.1
Had other major operations	0.1	0.2	0.9	0.4	0.0	0.4	0.1	0.1	0.6	0.6	0.4	-0.8	-0.0	-0.3	-0.1	0.1	0.2	-0.2	0.5	-0.2	-0.1	0.1	0.2	0.1	-0.9	0.9	0.4	0.5
Allergy	0.1	0.2	1.0	-0.8	0.1	0.1	0.4	-0.4	0.1	-0.8	0.8	0.6	0.1	0.2	0.2	0.1	-0.0	0.2	0.4	1.0	0.2	0.3	0.5	0.5	0.8	-0.4	0.2	-0.2
Alcohol intake versus 10 years previously	0.1	0.2	0.9	0.2	-0.2	-0.2	-0.7	-0.9	0.1	-1.0	0.1	0.0	-0.3	-0.2	-0.2	-0.1	-0.3	-0.2	0.2	-0.5	-0.3	-0.3	0.0	0.9	-0.6	0.2	0.2	0.1
Arm fat-free mass (right)	0.1	0.7	3.6	0.4	0.9	0.4	0.6	1.9	-1.7	0.3	0.6	0.4	0.9	0.7	0.8	0.1	0.9	0.8	0.2	0.4	0.8	-0.1	0.8	0.1	1.9	-0.7	0.5	0.5
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.6	-0.1	-0.3	-0.2	-0.3	-0.4	-0.1	-0.2	-0.3	-0.1	-0.3	-0.4	-0.3	-0.6	-0.2	-0.4	0.0	0.4	-0.4	-0.1	-0.2	0.1	-0.7	-0.4	-0.2	-0.0
Leg fat-free mass (right)	0.1	0.5	3.5	0.7	0.5	0.1	-0.2	0.2	-1.3	-0.3	0.2	0.5	0.5	0.4	0.5	-0.2	0.6	0.4	-0.1	0.5	0.4	-1.2	0.6	0.1	1.9	-1.5	0.2	0.2
Leg predicted mass (right)	0.1	0.5	3.5	0.6	0.6	0.2	-0.2	0.2	-1.3	-0.3	0.3	0.5	0.6	0.4	0.5	-0.1	0.6	0.5	-0.0	0.6	0.4	-1.1	0.7	0.1	1.9	-1.5	0.3	0.2
Basal metabolic rate	0.1	0.6	3.8	0.9	0.8	0.3	0.5	1.2	-1.0	0.3	0.4	0.5	0.7	0.6	0.7	0.1	0.8	0.7	0.1	0.4	0.7	-0.9	0.8	0.3	2.0	-1.1	0.5	0.4
Basal cell carcinoma (self-reported)	0.1	0.1	0.8	-0.9	0.1	0.1	0.0	0.3	-0.7	-0.5	0.1	-0.3	0.1	0.1	0.1	-0.0	0.1	0.1	0.3	-0.3	0.2	0.3	-0.2	-0.6	0.0	0.3	-0.0	-0.1
Arm predicted mass (left)	0.1	0.6	3.5	0.9	0.7	0.2	0.7	1.8	-1.4	0.5	0.4	0.3	0.7	0.6	0.7	0.1	0.7	0.7	-0.1	0.2	0.7	-0.5	0.6	0.1	1.9	-0.9	0.3	0.3

Hub : Genes

WNT3

Models

Trait associations